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Furylfuramide

Index Furylfuramide

Furylfuramide (also known as AF-2) is a synthetic nitrofuran derivative which was widely used as a food preservative in Japan since at least 1965, but withdrawn from the market in 1974 when it was observed to be mutagenic to bacteria in vitro and thus suspected of carcinogenicity. [1]

19 relations: Animal testing, Bacteria, Benignity, Cancer, Carcinogen, CRC Press, Esophagus, Food preservation, In vitro, International Agency for Research on Cancer, Japan, Lung, Mammary gland, Mutagen, Nitrofuran, Rodent, Sex, Stomach, World Health Organization.

Animal testing

Animal testing, also known as animal experimentation, animal research and in vivo testing, is the use of non-human animals in experiments that seek to control the variables that affect the behavior or biological system under study.

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Bacteria

Bacteria (common noun bacteria, singular bacterium) is a type of biological cell.

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Benignity

Benignity (from Latin benignus "kind, good", itself deriving from bonus "good" and genus "origin") is any condition that is harmless in the long run.

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Cancer

Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.

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Carcinogen

A carcinogen is any substance, radionuclide, or radiation that promotes carcinogenesis, the formation of cancer.

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CRC Press

The CRC Press, LLC is a publishing group based in the United States that specializes in producing technical books.

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Esophagus

The esophagus (American English) or oesophagus (British English), commonly known as the food pipe or gullet (gut), is an organ in vertebrates through which food passes, aided by peristaltic contractions, from the pharynx to the stomach.

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Food preservation

Food preservation prevents the growth of microorganisms (such as yeasts), or other microorganisms (although some methods work by introducing benign bacteria or fungi to the food), as well as slowing the oxidation of fats that cause rancidity.

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In vitro

In vitro (meaning: in the glass) studies are performed with microorganisms, cells, or biological molecules outside their normal biological context.

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International Agency for Research on Cancer

The International Agency for Research on Cancer (IARC; Centre International de Recherche sur le Cancer, CIRC) is an intergovernmental agency forming part of the World Health Organization of the United Nations.

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Japan

Japan (日本; Nippon or Nihon; formally 日本国 or Nihon-koku, lit. "State of Japan") is a sovereign island country in East Asia.

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Lung

The lungs are the primary organs of the respiratory system in humans and many other animals including a few fish and some snails.

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Mammary gland

A mammary gland is an exocrine gland in mammals that produces milk to feed young offspring.

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Mutagen

In genetics, a mutagen is a physical or chemical agent that changes the genetic material, usually DNA, of an organism and thus increases the frequency of mutations above the natural background level.

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Nitrofuran

Nitrofurans are a class of drugs typically used as antibiotics or antimicrobials.

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Rodent

Rodents (from Latin rodere, "to gnaw") are mammals of the order Rodentia, which are characterized by a single pair of continuously growing incisors in each of the upper and lower jaws.

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Sex

Organisms of many species are specialized into male and female varieties, each known as a sex. Sexual reproduction involves the combining and mixing of genetic traits: specialized cells known as gametes combine to form offspring that inherit traits from each parent.

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Stomach

The stomach (from ancient Greek στόμαχος, stomachos, stoma means mouth) is a muscular, hollow organ in the gastrointestinal tract of humans and many other animals, including several invertebrates.

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World Health Organization

The World Health Organization (WHO; French: Organisation mondiale de la santé) is a specialized agency of the United Nations that is concerned with international public health.

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Redirects here:

2-(2-furyl)-3-(5-nitro-2-furyl) acrylamide, 2-(2-furyl)-3-(5-nitro-2-furyl)acrylic acid amide, 2-furanacetamide, A-(furyl)-b-(5-nitro-2-furyl)acrylic amide, Alpha-2-furyl-5-nitro-2-furanacrylamide, C11H8N2O5, Tofuron, Trans-2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide.

References

[1] https://en.wikipedia.org/wiki/Furylfuramide

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