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16 relations: Angiogenesis inhibitor, Apoptosis, Caspase 8, Cluster of differentiation, Dendritic cell, Etaracizumab, Integrin, Integrin alpha V, Integrin beta 3, Macrophage, Phagocytosis, Platelet, Proteases in angiogenesis, Receptor (biochemistry), Vitaxin, Vitronectin.
Angiogenesis inhibitor
An angiogenesis inhibitor is a substance that inhibits the growth of new blood vessels (angiogenesis).
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Apoptosis
Apoptosis (from Ancient Greek ἀπόπτωσις "falling off") is a process of programmed cell death that occurs in multicellular organisms.
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Caspase 8
Caspase-8 is a caspase protein, encoded by the CASP8 gene.
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Cluster of differentiation
The cluster of differentiation (also known as cluster of designation or classification determinant and often abbreviated as CD) is a protocol used for the identification and investigation of cell surface molecules providing targets for immunophenotyping of cells.
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Dendritic cell
Dendritic cells (DCs) are antigen-presenting cells (also known as accessory cells) of the mammalian immune system.
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Etaracizumab
Etaracizumab (also known as etaratuzumab, MEDI-522, trade name Abegrin) is a humanized monoclonal antibody which is being investigated for the treatment of metastatic melanoma, prostate cancer, ovarian cancer and various other types of cancer.
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Integrin
Integrins are transmembrane receptors that facilitate cell-extracellular matrix (ECM) adhesion.
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Integrin alpha V
Integrin alpha-V is a protein that in humans is encoded by the ITGAV gene.
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Integrin beta 3
Integrin beta-3 (β3) or CD61 is a protein that in humans is encoded by the ITGB3 gene.
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Macrophage
Macrophages (big eaters, from Greek μακρός (makrós).
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Phagocytosis
In cell biology, phagocytosis is the process by which a cell—often a phagocyte or a protist—engulfs a solid particle to form an internal compartment known as a phagosome.
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Platelet
Platelets, also called thrombocytes (from Greek θρόμβος, "clot" and κύτος, "cell"), are a component of blood whose function (along with the coagulation factors) is to react to bleeding from blood vessel injury by clumping, thereby initiating a blood clot.
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Proteases in angiogenesis
Angiogenesis is the process of forming new blood vessels from existing blood vessels.
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Receptor (biochemistry)
In biochemistry and pharmacology, a receptor is a protein molecule that receives chemical signals from outside a cell.
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Vitaxin
Vitaxin is a humanized monoclonal antibody against the vascular integrin alpha-v beta-3.
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Vitronectin
Vitronectin (VTN or VN) is a glycoprotein of the hemopexin family which is abundantly found in serum, the extracellular matrix and bone.
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Alpha-V beta-3, Vibronectin, Vitronectin receptor, ΑVβ3, Αvβ3.
