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Altanserin

Index Altanserin

Altanserin is a compound that binds to the 5-HT2A receptor (5-Hydroxytryptamine (serotonin) 2A receptor). [1]

79 relations: Ageing, Alzheimer's disease, American Journal of Psychiatry, Amygdala, Anorexia nervosa, Anterior cingulate cortex, At risk mental state, Autoradiograph, Biological Psychiatry (journal), Body mass index, Borderline personality disorder, Brain, Brain Research, Brain Structure and Function, British Journal of Psychiatry, Brodmann area 25, Bulimia nervosa, Caudate nucleus, Cerebellum, Cerebral cortex, DASB, Deuterium, European Journal of Nuclear Medicine and Molecular Imaging, Fluorine-18, Gender, Hippocampus, Immunoassay, In vitro, Insular cortex, Isothiocyanate, Isotope, Isotopes of carbon, Journal of Cerebral Blood Flow & Metabolism, Ketanserin, Major depressive disorder, Mental disorder, Mild cognitive impairment, Molecular binding, Motor cortex, Neocortex, Neurobiology of Aging, NeuroImage, Neuroimaging, Neuropsychopharmacology (journal), Neuroscience Letters, Neuroticism, Neurotransmitter receptor, Obsessive–compulsive disorder, Occipital lobe, Orbitofrontal cortex, ..., Parietal lobe, Positron emission tomography, Prefrontal cortex, Psychiatry Research, Psychopharmacology (journal), Purkinje cell, Radioligand, Rat, Receptor antagonist, Reproducibility, Revised NEO Personality Inventory, Schizophrenia, Science (journal), Serotonin, Setoperone, Single-photon emission computed tomography, Synapse (journal), The International Journal of Neuropsychopharmacology, The Journal of Nuclear Medicine, Thioketone, Thiophosgene, Tourette syndrome, Trait theory, Tritium, Twin, Volinanserin, WAY-100635, 5-HT2A receptor, 5-I-R91150. Expand index (29 more) »

Ageing

Ageing or aging (see spelling differences) is the process of becoming older.

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Alzheimer's disease

Alzheimer's disease (AD), also referred to simply as Alzheimer's, is a chronic neurodegenerative disease that usually starts slowly and worsens over time.

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American Journal of Psychiatry

The American Journal of Psychiatry is a monthly peer-reviewed medical journal covering all aspects of psychiatry and the official journal of the American Psychiatric Association.

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Amygdala

The amygdala (plural: amygdalae; also corpus amygdaloideum; Latin from Greek, ἀμυγδαλή, amygdalē, 'Almond', 'tonsil') is one of two almond-shaped groups of nuclei located deep and medially within the temporal lobes of the brain in complex vertebrates, including humans.

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Anorexia nervosa

Anorexia nervosa, often referred to simply as anorexia, is an eating disorder characterized by low weight, fear of gaining weight, and a strong desire to be thin, resulting in food restriction.

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Anterior cingulate cortex

The anterior cingulate cortex (ACC) is the frontal part of the cingulate cortex that resembles a "collar" surrounding the frontal part of the corpus callosum.

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At risk mental state

At risk mental state is the clinical presentation of those considered at risk of developing psychosis or schizophrenia.

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Autoradiograph

An autoradiograph is an image on an x-ray film or nuclear emulsion produced by the pattern of decay emissions (e.g., beta particles or gamma rays) from a distribution of a radioactive substance.

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Biological Psychiatry (journal)

Biological Psychiatry is a biweekly, peer-reviewed, scientific journal of psychiatric neuroscience and therapeutics, published by Elsevier since 1985 on behalf of the Society of Biological Psychiatry, of which it is the official journal.

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Body mass index

The body mass index (BMI) or Quetelet index is a value derived from the mass (weight) and height of an individual.

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Borderline personality disorder

Borderline personality disorder (BPD), also known as emotionally unstable personality disorder (EUPD), is a long-term pattern of abnormal behavior characterized by unstable relationships with other people, unstable sense of self, and unstable emotions.

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Brain

The brain is an organ that serves as the center of the nervous system in all vertebrate and most invertebrate animals.

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Brain Research

Brain Research is a peer-reviewed scientific journal focusing on several aspects of neuroscience.

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Brain Structure and Function

Brain Structure and Function is a bimonthly peer-reviewed scientific journal covering research on brain structure-function relationships.

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British Journal of Psychiatry

The British Journal of Psychiatry is a peer-reviewed medical journal published monthly by the Royal College of Psychiatrists containing original research, systematic reviews, commentaries on contentious articles, short reports, a comprehensive book review section, and a correspondence column relating to all aspects of psychiatry.

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Brodmann area 25

Brodmann area 25 (BA25) is an area in the cerebral cortex of the brain and delineated based on its cytoarchitectonic characteristics.

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Bulimia nervosa

Bulimia nervosa, also known as simply bulimia, is an eating disorder characterized by binge eating followed by purging.

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Caudate nucleus

The caudate nucleus is one of the structures that make up the dorsal striatum, which is a component of the basal ganglia.

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Cerebellum

The cerebellum (Latin for "little brain") is a major feature of the hindbrain of all vertebrates.

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Cerebral cortex

The cerebral cortex is the largest region of the cerebrum in the mammalian brain and plays a key role in memory, attention, perception, cognition, awareness, thought, language, and consciousness.

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DASB

DASB, 3-amino-4-(2-dimethylaminomethylphenylsulfanyl)-benzonitrile, is a compound that binds to the serotonin transporter.

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Deuterium

Deuterium (or hydrogen-2, symbol or, also known as heavy hydrogen) is one of two stable isotopes of hydrogen (the other being protium, or hydrogen-1).

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European Journal of Nuclear Medicine and Molecular Imaging

The European Journal of Nuclear Medicine and Molecular Imaging (EJNMMI) is a peer-reviewed medical journal published by Springer.

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Fluorine-18

Fluorine-18 (18F) is a fluorine radioisotope which is an important source of positrons.

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Gender

Gender is the range of characteristics pertaining to, and differentiating between, masculinity and femininity.

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Hippocampus

The hippocampus (named after its resemblance to the seahorse, from the Greek ἱππόκαμπος, "seahorse" from ἵππος hippos, "horse" and κάμπος kampos, "sea monster") is a major component of the brains of humans and other vertebrates.

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Immunoassay

An immunoassay is a biochemical test that measures the presence or concentration of a macromolecule or a small molecule in a solution through the use of an antibody (usually) or an antigen (sometimes).

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In vitro

In vitro (meaning: in the glass) studies are performed with microorganisms, cells, or biological molecules outside their normal biological context.

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Insular cortex

In each hemisphere of the mammalian brain the insular cortex (also insula and insular lobe) is a portion of the cerebral cortex folded deep within the lateral sulcus (the fissure separating the temporal lobe from the parietal and frontal lobes).

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Isothiocyanate

Isothiocyanate is the chemical group –N.

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Isotope

Isotopes are variants of a particular chemical element which differ in neutron number.

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Isotopes of carbon

Carbon (6C) has 15 known isotopes, from 8C to 22C, of which 12C and 13C are stable.

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Journal of Cerebral Blood Flow & Metabolism

The Journal of Cerebral Blood Flow & Metabolism is a monthly peer-reviewed medical journal the official journal of the International Society for Cerebral Blood Flow & Metabolism and publishes peer-reviewed research and review papers.

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Ketanserin

Ketanserin (INN, USAN, BAN) (brand name Sufrexal; former developmental code name R41468) is a drug used clinically as an antihypertensive agent and in scientific research to study the serotonin system; specifically, the 5-HT2 receptor family.

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Major depressive disorder

Major depressive disorder (MDD), also known simply as depression, is a mental disorder characterized by at least two weeks of low mood that is present across most situations.

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Mental disorder

A mental disorder, also called a mental illness or psychiatric disorder, is a behavioral or mental pattern that causes significant distress or impairment of personal functioning.

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Mild cognitive impairment

Mild cognitive impairment (MCI), also known as incipient dementia and isolated memory impairment, is a neurological disorder that occurs in older adults which involves cognitive impairments with minimal impairment in instrumental activities of daily living.

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Molecular binding

Molecular binding is an attractive interaction between two molecules that results in a stable association in which the molecules are in close proximity to each other.

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Motor cortex

The motor cortex is the region of the cerebral cortex involved in the planning, control, and execution of voluntary movements.

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Neocortex

The neocortex, also called the neopallium and isocortex, is the part of the mammalian brain involved in higher-order brain functions such as sensory perception, cognition, generation of motor commands, spatial reasoning and language.

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Neurobiology of Aging

Neurobiology of Aging is a peer-reviewed monthly scientific journal published by Elsevier.

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NeuroImage

NeuroImage is a peer-reviewed scientific journal covering research on neuroimaging, including functional neuroimaging and functional human brain mapping.

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Neuroimaging

Neuroimaging or brain imaging is the use of various techniques to either directly or indirectly image the structure, function/pharmacology of the nervous system.

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Neuropsychopharmacology (journal)

Neuropsychopharmacology is a peer-reviewed scientific journal published by the Nature Publishing Group.

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Neuroscience Letters

Neuroscience Letters is a biweekly rapid-publication scientific journal for short articles covering all aspects of neuroscience.

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Neuroticism

Neuroticism is one of the Big Five higher-order personality traits in the study of psychology.

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Neurotransmitter receptor

A neurotransmitter receptor (also known as a neuroreceptor) is a membrane receptor protein that is activated by a neurotransmitter.

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Obsessive–compulsive disorder

Obsessive–compulsive disorder (OCD) is a mental disorder where people feel the need to check things repeatedly, perform certain routines repeatedly (called "rituals"), or have certain thoughts repeatedly (called "obsessions").

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Occipital lobe

The occipital lobe is one of the four major lobes of the cerebral cortex in the brain of mammals.

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Orbitofrontal cortex

The orbitofrontal cortex (OFC) is a prefrontal cortex region in the frontal lobes in the brain which is involved in the cognitive processing of decision-making.

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Parietal lobe

The parietal lobe is one of the four major lobes of the cerebral cortex in the brain of mammals. The parietal lobe is positioned above the temporal lobe and behind the frontal lobe and central sulcus. The parietal lobe integrates sensory information among various modalities, including spatial sense and navigation (proprioception), the main sensory receptive area for the sense of touch (mechanoreception) in the somatosensory cortex which is just posterior to the central sulcus in the postcentral gyrus, and the dorsal stream of the visual system. The major sensory inputs from the skin (touch, temperature, and pain receptors), relay through the thalamus to the parietal lobe. Several areas of the parietal lobe are important in language processing. The somatosensory cortex can be illustrated as a distorted figure – the homunculus (Latin: "little man"), in which the body parts are rendered according to how much of the somatosensory cortex is devoted to them.Schacter, D. L., Gilbert, D. L. & Wegner, D. M. (2009). Psychology. (2nd ed.). New York (NY): Worth Publishers. The superior parietal lobule and inferior parietal lobule are the primary areas of body or spacial awareness. A lesion commonly in the right superior or inferior parietal lobule leads to hemineglect. The name comes from the parietal bone, which is named from the Latin paries-, meaning "wall".

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Positron emission tomography

Positron-emission tomography (PET) is a nuclear medicine functional imaging technique that is used to observe metabolic processes in the body as an aid to the diagnosis of disease.

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Prefrontal cortex

In mammalian brain anatomy, the prefrontal cortex (PFC) is the cerebral cortex which covers the front part of the frontal lobe.

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Psychiatry Research

Psychiatry Research is a peer-reviewed medical journal covering psychiatry.

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Psychopharmacology (journal)

Psychopharmacology is a peer-reviewed scientific journal covering psychopharmacology that is published by Springer Science+Business Media.

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Purkinje cell

Purkinje cells, or Purkinje neurons, are a class of GABAergic neurons located in the cerebellum.

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Radioligand

A radioligand is a radioactive biochemical substance (in particular, a ligand that is radiolabeled) that is used for diagnosis or for research-oriented study of the receptor systems of the body.

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Rat

Rats are various medium-sized, long-tailed rodents in the superfamily Muroidea.

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Receptor antagonist

A receptor antagonist is a type of receptor ligand or drug that blocks or dampens a biological response by binding to and blocking a receptor rather than activating it like an agonist.

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Reproducibility

Reproducibility is the closeness of the agreement between the results of measurements of the same measurand carried out under changed conditions of measurement.

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Revised NEO Personality Inventory

The Revised NEO Personality Inventory (NEO PI-R) is a personality inventory that examines a person's Big Five personality traits (openness to experience, conscientiousness, extraversion, agreeableness, and neuroticism).

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Schizophrenia

Schizophrenia is a mental disorder characterized by abnormal social behavior and failure to understand reality.

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Science (journal)

Science, also widely referred to as Science Magazine, is the peer-reviewed academic journal of the American Association for the Advancement of Science (AAAS) and one of the world's top academic journals.

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Serotonin

Serotonin or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter.

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Setoperone

Setoperone is a compound that is a ligand to the 5-HT2A receptor.

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Single-photon emission computed tomography

Single-photon emission computed tomography (SPECT, or less commonly, SPET) is a nuclear medicine tomographic imaging technique using gamma rays.

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Synapse (journal)

Synapse is a peer-reviewed scientific journal of neuroscience published in New York City by Wiley-Liss to address basic science topics on synaptic function and structure.

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The International Journal of Neuropsychopharmacology

The International Journal of Neuropsychopharmacology is a peer-reviewed scientific journal published by Oxford University Press.

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The Journal of Nuclear Medicine

The Journal of Nuclear Medicine is a monthly peer-reviewed medical journal published by Society of Nuclear Medicine and Molecular Imaging that covers research on all aspects of nuclear medicine, including molecular imaging.

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Thioketone

Thioketones (also known as thiones or thiocarbonyls) are organosulfur compounds related to conventional ketones.

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Thiophosgene

Thiophosgene is a red liquid with the formula CSCl2.

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Tourette syndrome

Tourette syndrome (TS or simply Tourette's) is a common neuropsychiatric disorder with onset in childhood, characterized by multiple motor tics and at least one vocal (phonic) tic.

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Trait theory

In psychology, trait theory (also called dispositional theory) is an approach to the study of human personality.

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Tritium

Tritium (or; symbol or, also known as hydrogen-3) is a radioactive isotope of hydrogen.

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Twin

Twins are two offspring produced by the same pregnancy.

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Volinanserin

Volinanserin (INN) (developmental code name MDL-100,907) is a highly selective 5-HT2A receptor antagonist that is frequently used in scientific research to investigate the function of the 5-HT2A receptor.

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WAY-100635

WAY-100635 is a piperazine drug and research chemical widely used in scientific studies.

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5-HT2A receptor

The mammalian 5-HT2A receptor is a subtype of the 5-HT2 receptor that belongs to the serotonin receptor family and is a G protein-coupled receptor (GPCR).

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5-I-R91150

5-I-R91150 (or R93274) is a compound that acts as a potent and selective antagonist of 5-HT2A receptors.

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References

[1] https://en.wikipedia.org/wiki/Altanserin

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