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Altogen Labs CRO

Index Altogen Labs CRO

Altogen Labs CRO is a contract research organization (CRO) based in Austin, Texas that is involved in pharmacological discovery and drug development. [1]

40 relations: Austin, Texas, Bacteria, Biodistribution, Bioremediation, Biotechnology, Cancer, Cancer cell, Cell culture, Chemotherapy, Clinical trial, Contract research organization, Cytotoxicity, DNA methylation, Gene expression, Gene therapy, Good laboratory practice, Hexachlorodisilane, High-throughput screening, Immortalised cell line, In vitro, In vivo, Institutional Animal Care and Use Committee, Investigational New Drug, Mechanism of action, Medication, Metastasis, Patient derived xenograft, Pharmacology, Protein production, Pyrosequencing, RNA interference, Semiconductor, Severe combined immunodeficient mice, Small interfering RNA, Toxicology, Transfection, Transparency Market Research, United States, University of Texas at Austin, Xenotransplantation.

Austin, Texas

Austin is the capital of the U.S. state of Texas and the seat of Travis County, with portions extending into Hays and Williamson counties.

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Bacteria

Bacteria (common noun bacteria, singular bacterium) is a type of biological cell.

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Biodistribution

Biodistribution is a method of tracking where compounds of interest travel in an experimental animal or human subject.

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Bioremediation

Bioremediation is a process used to treat contaminated media, including water, soil and subsurface material, by altering environmental conditions to stimulate growth of microorganisms and degrade the target pollutants.

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Biotechnology

Biotechnology is the broad area of science involving living systems and organisms to develop or make products, or "any technological application that uses biological systems, living organisms, or derivatives thereof, to make or modify products or processes for specific use" (UN Convention on Biological Diversity, Art. 2).

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Cancer

Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.

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Cancer cell

Cancer cells are cells that divide relentlessly, forming solid tumors or flooding the blood with abnormal cells.

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Cell culture

Cell culture is the process by which cells are grown under controlled conditions, generally outside their natural environment.

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Chemotherapy

Chemotherapy (often abbreviated to chemo and sometimes CTX or CTx) is a type of cancer treatment that uses one or more anti-cancer drugs (chemotherapeutic agents) as part of a standardized chemotherapy regimen.

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Clinical trial

Clinical trials are experiments or observations done in clinical research.

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Contract research organization

A contract research organization (CRO) is a company that provides support to the pharmaceutical, biotechnology, and medical device industries in the form of research services outsourced on a contract basis.

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Cytotoxicity

Cytotoxicity is the quality of being toxic to cells.

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DNA methylation

DNA methylation is a process by which methyl groups are added to the DNA molecule.

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Gene expression

Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product.

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Gene therapy

In the medicine field, gene therapy (also called human gene transfer) is the therapeutic delivery of nucleic acid into a patient's cells as a drug to treat disease.

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Good laboratory practice

In the experimental (non-clinical) research arena, the phrase good laboratory practice or GLP specifically refers to a quality system of management controls for research laboratories and organizations to ensure the uniformity, consistency, reliability, reproducibility, quality, and integrity of chemical (including pharmaceuticals) non-clinical safety tests; from physio-chemical properties through acute to chronic toxicity tests.

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Hexachlorodisilane

Hexachlorodisilane is the inorganic compound with the chemical formula Si2Cl6,Simmler, W. "Silicon Compounds, Inorganic", Ullmann's Encyclopedia of Industrial Chemistry, Weinheim: Wiley-VCH.

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High-throughput screening

High-throughput screening (HTS) is a method for scientific experimentation especially used in drug discovery and relevant to the fields of biology and chemistry.

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Immortalised cell line

An immortalized cell line is a population of cells from a multicellular organism which would normally not proliferate indefinitely but, due to mutation, have evaded normal cellular senescence and instead can keep undergoing division.

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In vitro

In vitro (meaning: in the glass) studies are performed with microorganisms, cells, or biological molecules outside their normal biological context.

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In vivo

Studies that are in vivo (Latin for "within the living"; often not italicized in English) are those in which the effects of various biological entities are tested on whole, living organisms or cells, usually animals, including humans, and plants, as opposed to a tissue extract or dead organism.

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Institutional Animal Care and Use Committee

Institutional Animal Care and Use Committees (IACUCs) are centrally important in applying laws about animal research in the United States.

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Investigational New Drug

The United States Food and Drug Administration's Investigational New Drug (IND) program is the means by which a pharmaceutical company obtains permission to ship an experimental drug across state lines (usually to clinical investigators) before a marketing application for the drug has been approved.

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Mechanism of action

In pharmacology, the term mechanism of action (MOA) refers to the specific biochemical interaction through which a drug substance produces its pharmacological effect.

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Medication

A medication (also referred to as medicine, pharmaceutical drug, or simply drug) is a drug used to diagnose, cure, treat, or prevent disease.

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Metastasis

Metastasis is a pathogenic agent's spread from an initial or primary site to a different or secondary site within the host's body; it is typically spoken of as such spread by a cancerous tumor.

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Patient derived xenograft

Patient derived xenografts (PDX) are models of cancer where the tissue or cells from a patient's tumor are implanted into an immunodeficient or humanized mouse.

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Pharmacology

Pharmacology is the branch of biology concerned with the study of drug action, where a drug can be broadly defined as any man-made, natural, or endogenous (from within body) molecule which exerts a biochemical or physiological effect on the cell, tissue, organ, or organism (sometimes the word pharmacon is used as a term to encompass these endogenous and exogenous bioactive species).

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Protein production

Protein production is the biotechnological process of generating a specific protein.

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Pyrosequencing

Pyrosequencing is a method of DNA sequencing (determining the order of nucleotides in DNA) based on the "sequencing by synthesis" principle, in which the sequencing is performed by detecting the nucleotide incorporated by a DNA polymerase.

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RNA interference

RNA interference (RNAi) is a biological process in which RNA molecules inhibit gene expression or translation, by neutralizing targeted mRNA molecules.

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Semiconductor

A semiconductor material has an electrical conductivity value falling between that of a conductor – such as copper, gold etc.

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Severe combined immunodeficient mice

Mice with severe combined immunodeficiency (SCIDs) are often used in the research of human disease.

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Small interfering RNA

Small interfering RNA (siRNA), sometimes known as short interfering RNA or silencing RNA, is a class of double-stranded RNA molecules, 20-25 base pairs in length, similar to miRNA, and operating within the RNA interference (RNAi) pathway.

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Toxicology

Toxicology is a discipline, overlapping with biology, chemistry, pharmacology, and medicine, that involves the study of the adverse effects of chemical substances on living organisms and the practice of diagnosing and treating exposures to toxins and toxicants.

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Transfection

Transfection is the process of deliberately introducing naked or purified nucleic acids into eukaryotic cells.

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Transparency Market Research

Transparency Market Research (TMR) is a global market research, analysis, and intelligence firm with offices in India and the U.S. The company was founded in 2011 and registered as a private limited company in India in 2013.

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United States

The United States of America (USA), commonly known as the United States (U.S.) or America, is a federal republic composed of 50 states, a federal district, five major self-governing territories, and various possessions.

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University of Texas at Austin

The University of Texas at Austin (UT, UT Austin, or Texas) is a public research university and the flagship institution of the University of Texas System.

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Xenotransplantation

Xenotransplantation (xenos- from the Greek meaning "foreign"), is the transplantation of living cells, tissues or organs from one species to another.

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References

[1] https://en.wikipedia.org/wiki/Altogen_Labs_CRO

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