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Amino acid reuptake inhibitor

Index Amino acid reuptake inhibitor

An amino acid reuptake inhibitor (AARI) is a type of drug which inhibits the reuptake of one or more amino acid neurotransmitters (i.e., glutamate, aspartate, GABA, and/or glycine) by blocking one or more of their respective transporters. [1]

13 relations: Amino acid neurotransmitter, Aspartic acid, Drug, Excitatory amino acid reuptake inhibitor, GABA reuptake inhibitor, Gamma-Aminobutyric acid, Glutamic acid, Glycine, Glycine reuptake inhibitor, Monoamine reuptake inhibitor, Neurotransmitter transporter, Reuptake, Reuptake inhibitor.

Amino acid neurotransmitter

An amino acid neurotransmitter is an amino acid which is able to transmit a nerve message across a synapse.

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Aspartic acid

Aspartic acid (symbol Asp or D; salts known as aspartates), is an α-amino acid that is used in the biosynthesis of proteins.

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Drug

A drug is any substance (other than food that provides nutritional support) that, when inhaled, injected, smoked, consumed, absorbed via a patch on the skin, or dissolved under the tongue causes a temporary physiological (and often psychological) change in the body.

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Excitatory amino acid reuptake inhibitor

An excitatory amino acid reuptake inhibitor (EAARI) is a type of drug which inhibits the reuptake of the excitatory neurotransmitters glutamate and aspartate by blocking one or more of the excitatory amino acid transporters (EAATs).

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GABA reuptake inhibitor

A GABA reuptake inhibitor (GRI) is a type of drug which acts as a reuptake inhibitor for the neurotransmitter gamma-Aminobutyric acid (GABA) by blocking the action of the gamma-Aminobutyric acid transporters (GATs).

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Gamma-Aminobutyric acid

gamma-Aminobutyric acid, or γ-aminobutyric acid, or GABA, is the chief inhibitory neurotransmitter in the mammalian central nervous system.

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Glutamic acid

Glutamic acid (symbol Glu or E) is an α-amino acid with formula.

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Glycine

Glycine (symbol Gly or G) is the amino acid that has a single hydrogen atom as its side chain.

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Glycine reuptake inhibitor

A glycine reuptake inhibitor (GRI) is a type of drug which inhibits the reuptake of the neurotransmitter glycine by blocking one or more of the glycine transporters (GlyTs).

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Monoamine reuptake inhibitor

A monoamine reuptake inhibitor (MRI) is a drug that acts as a reuptake inhibitor of one or more of the three major monoamine neurotransmitters serotonin, norepinephrine, and dopamine by blocking the action of one or more of the respective monoamine transporters (MATs), which include the serotonin transporter (SERT), norepinephrine transporter (NET), and dopamine transporter (DAT).

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Neurotransmitter transporter

Neurotransmitter transporters are a class of membrane transport proteins that span the cellular membranes of neurons.

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Reuptake

Reuptake is the reabsorption of a neurotransmitter by a neurotransmitter transporter located along the plasma membrane of an axon terminal (i.e., the pre-synaptic neuron at a synapse) or glial cell after it has performed its function of transmitting a neural impulse.

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Reuptake inhibitor

A reuptake inhibitor (RI) is a type of drug known as a reuptake modulator that inhibits the plasmalemmal transporter-mediated reuptake of a neurotransmitter from the synapse into the pre-synaptic neuron.

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Redirects here:

Amino acid uptake inhibitor, Inhibitory amino acid reuptake inhibitor, Inhibitory amino acid uptake inhibitor.

References

[1] https://en.wikipedia.org/wiki/Amino_acid_reuptake_inhibitor

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