108 relations: Abdominal pain, ACE inhibitor, Adrenal gland, Adrenaline, Aliskiren, Aliskiren/amlodipine, Aliskiren/amlodipine/hydrochlorothiazide, Amine, Amlodipine/benazepril, Amlodipine/valsartan, Angina, Angiotensin, Angiotensin II receptor blocker, Angiotensin-converting enzyme, Antihypotensive agent, Antimineralocorticoid, Aorta, Aortic stenosis, Atorvastatin/amlodipine, Atrium (heart), Benazepril, Benzenesulfonic acid, Blood, Breastfeeding, Calcium channel blocker, Cardiac muscle cell, Cardiogenic shock, Cav1.3, Chronic kidney disease, Ciclosporin, Clarithromycin, Contraindication, Coronary arteries, Coronary artery disease, CYP3A4, Dihydropyridine, Diltiazem, Dizziness, Edema, Electrocardiography, Erectile dysfunction, Essential hypertension, Ester, Extracellular fluid, Fatigue, Fluid replacement, Flushing (physiology), Generic drug, Gingival enlargement, Health system, ..., Heart failure, Hepatitis, Hydrochlorothiazide, Hydrolysis, Hypertension, Hypotension, Inotrope, Insomnia, Jaundice, Kidney disease, L-type calcium channel, Lipid-lowering agent, Liver, Major depressive disorder, Maleic acid, Mesylate, Mineralocorticoid receptor, Mitral insufficiency, Myocardial infarction, Myopathy, Nausea, Olmesartan, Oral administration, Palpitations, Patent, Perindopril, Peripheral edema, Peripheral neuropathy, Pfizer, Pharmacodynamics, Pregnancy, Pulmonary edema, Pyridine, Racemic mixture, Rate pressure product, Receptor antagonist, Renin, Renin inhibitor, Renin–angiotensin system, Serotonin, Sildenafil, Simvastatin, Somnolence, Tachycardia, Tacrolimus, Telmisartan, Thromboxane A2, Urine, Valsartan, Variant angina, Vascular resistance, Vascular smooth muscle, Vasodilation, Vasospasm, Ventricle (heart), Ventricular septal defect, WHO Model List of Essential Medicines, Zona glomerulosa. Expand index (58 more) »
Abdominal pain
Abdominal pain, also known as a stomach ache, is a symptom associated with both non-serious and serious medical issues.
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ACE inhibitor
An angiotensin-converting-enzyme inhibitor (ACE inhibitor) is a pharmaceutical drug used primarily for the treatment of hypertension (elevated blood pressure) and congestive heart failure.
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Adrenal gland
The adrenal glands (also known as suprarenal glands) are endocrine glands that produce a variety of hormones including adrenaline and the steroids aldosterone and cortisol.
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Adrenaline
Adrenaline, also known as adrenalin or epinephrine, is a hormone, neurotransmitter, and medication.
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Aliskiren
Aliskiren (trade names Tekturna and Rasilez) is the first in a class of drugs called direct renin inhibitors.
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Aliskiren/amlodipine
The drug combination aliskiren/amlodipine (INNs, trade name Tekamlo) is an antihypertensive.
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Aliskiren/amlodipine/hydrochlorothiazide
The drug combination aliskiren/amlodipine/hydrochlorothiazide (INNs, trade name Amturnide) is an antihypertensive approved by the U.S. Food and Drug Administration (FDA) on December 21, 2010.
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Amine
In organic chemistry, amines are compounds and functional groups that contain a basic nitrogen atom with a lone pair.
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Amlodipine/benazepril
Amlodipine/benazepril, marketed in the U.S. as Lotrel by Novartis and manufactured as a generic drug by Teva and Sandoz, is an antihypertensive medication which combines a calcium channel blocker (amlodipine besilate) with an angiotensin converting enzyme inhibitor (benazepril).
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Amlodipine/valsartan
Amlodipine/valsartan is of an oral blood pressure lowering combination drug which combines two medications in a film-coated tablet.
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Angina
Angina, also known as angina pectoris, is chest pain or pressure, usually due to not enough blood flow to the heart muscle.
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Angiotensin
Angiotensin is a peptide hormone that causes vasoconstriction and an increase in blood pressure.
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Angiotensin II receptor blocker
Angiotensin II receptor blockers (ARBs), also known as angiotensin II receptor antagonists, AT1 receptor antagonists or sartans, are a group of pharmaceuticals that modulate the renin–angiotensin system.
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Angiotensin-converting enzyme
Angiotensin-converting enzyme, or ACE, is a central component of the renin–angiotensin system (RAS), which controls blood pressure by regulating the volume of fluids in the body.
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Antihypotensive agent
An antihypotensive agent, also known as a vasopressor agent or pressor, is any medication that tends to raise reduced blood pressure.
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Antimineralocorticoid
An antimineralocorticoid, MCRA, or an aldosterone antagonist, is a diuretic drug which antagonizes the action of aldosterone at mineralocorticoid receptors.
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Aorta
The aorta is the main artery in the human body, originating from the left ventricle of the heart and extending down to the abdomen, where it splits into two smaller arteries (the common iliac arteries).
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Aortic stenosis
Aortic stenosis (AS or AoS) is the narrowing of the exit of the left ventricle of the heart (where the aorta begins), such that problems result.
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Atorvastatin/amlodipine
The drug combination atorvastatin/amlodipine (trade names Caduet in the US, Australia and Russia, and Envacar elsewhere) is a medication approved by the Food and Drug Administration (FDA) for the treatment of high cholesterol and high blood pressure.
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Atrium (heart)
The atrium is the upper chamber in which blood enters the heart.
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Benazepril
Benazepril, brand name Lotensin (Novartis), is an ACE inhibitor used primarily in treatment of hypertension, congestive heart failure, and heart attacks, and also in preventing the renal and retinal complications of diabetes.
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Benzenesulfonic acid
Benzenesulfonic acid (conjugate base benzenesulfonate) is an organosulfur compound with the formula C6H5SO3H.
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Blood
Blood is a body fluid in humans and other animals that delivers necessary substances such as nutrients and oxygen to the cells and transports metabolic waste products away from those same cells.
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Breastfeeding
Breastfeeding, also known as nursing, is the feeding of babies and young children with milk from a woman's breast.
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Calcium channel blocker
Calcium channel blockers (CCB), calcium channel antagonists or calcium antagonists are several medications that disrupt the movement of calcium through calcium channels.
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Cardiac muscle cell
Cardiac muscle cells or cardiomyocytes (also known as myocardiocytes or cardiac myocytes) are the muscle cells (myocytes) that make up the cardiac muscle (heart muscle).
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Cardiogenic shock
Cardiogenic shock is a medical emergency resulting from inadequate blood flow due to the dysfunction of the ventricles of the heart.
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Cav1.3
Calcium channel, voltage-dependent, L type, alpha 1D subunit (also known as Cav1.3) is a protein that in humans is encoded by the CACNA1D gene.
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Chronic kidney disease
Chronic kidney disease (CKD) is a type of kidney disease in which there is gradual loss of kidney function over a period of months or years.
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Ciclosporin
Ciclosporin, also spelled cyclosporine and cyclosporin, is an immunosuppressant medication and natural product.
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Clarithromycin
Clarithromycin, sold under the brand name Biaxin among others, is an antibiotic used to treat various bacterial infections.
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Contraindication
In medicine, a contraindication is a condition or factor that serves as a reason to withhold a certain medical treatment due to the harm that it would cause the patient.
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Coronary arteries
The coronary arteries are the arteries of the coronary circulation that transport blood into and out of the cardiac muscle.
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Coronary artery disease
Coronary artery disease (CAD), also known as ischemic heart disease (IHD), refers to a group of diseases which includes stable angina, unstable angina, myocardial infarction, and sudden cardiac death.
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CYP3A4
Cytochrome P450 3A4 (abbreviated CYP3A4) is an important enzyme in the body, mainly found in the liver and in the intestine.
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Dihydropyridine
Dihydropyridine is a molecule based upon pyridine, and the parent of a class of molecules that have been semi-saturated with two substituents replacing one double bond.
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Diltiazem
Diltiazem (INN) is a nondihydropyridine (non-DHP) calcium channel blocker used in the treatment of hypertension, angina pectoris, and some types of arrhythmia.
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Dizziness
Dizziness is an impairment in spatial perception and stability.
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Edema
Edema, also spelled oedema or œdema, is an abnormal accumulation of fluid in the interstitium, located beneath the skin and in the cavities of the body, which can cause severe pain.
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Electrocardiography
Electrocardiography (ECG or EKG) is the process of recording the electrical activity of the heart over a period of time using electrodes placed on the skin.
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Erectile dysfunction
Erectile dysfunction (ED), also known as impotence, is a type of sexual dysfunction characterized by the inability to develop or maintain an erection of the penis during sexual activity.
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Essential hypertension
Essential hypertension (also called primary hypertension or idiopathic hypertension) is the form of hypertension that by definition has no identifiable cause.
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Ester
In chemistry, an ester is a chemical compound derived from an acid (organic or inorganic) in which at least one –OH (hydroxyl) group is replaced by an –O–alkyl (alkoxy) group.
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Extracellular fluid
Extracellular fluid (ECF) denotes all body fluid outside the cells.
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Fatigue
Fatigue is a subjective feeling of tiredness that has a gradual onset.
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Fluid replacement
Fluid replacement or fluid resuscitation is the medical practice of replenishing bodily fluid lost through sweating, bleeding, fluid shifts or other pathologic processes.
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Flushing (physiology)
For a person to flush is to become markedly red in the face and often other areas of the skin, from various physiological conditions.
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Generic drug
A generic drug is a pharmaceutical drug that is equivalent to a brand-name product in dosage, strength, route of administration, quality, performance, and intended use, but does not carry the brand name.
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Gingival enlargement
Gingival enlargement, (also termed gingival overgrowth, hypertrophic gingivitis, gingival hyperplasia, or gingival hypertrophy, and sometimes abbreviated to GO), is an increase in the size of the gingiva (gums).
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Health system
A health system, also sometimes referred to as health care system or as healthcare system, is the organization of people, institutions, and resources that deliver health care services to meet the health needs of target populations.
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Heart failure
Heart failure (HF), often referred to as congestive heart failure (CHF), is when the heart is unable to pump sufficiently to maintain blood flow to meet the body's needs.
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Hepatitis
Hepatitis is inflammation of the liver tissue.
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Hydrochlorothiazide
Hydrochlorothiazide (HCTZ or HCT) is a diuretic medication often used to treat high blood pressure and swelling due to fluid build up.
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Hydrolysis
Hydrolysis is a term used for both an electro-chemical process and a biological one.
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Hypertension
Hypertension (HTN or HT), also known as high blood pressure (HBP), is a long-term medical condition in which the blood pressure in the arteries is persistently elevated.
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Hypotension
Hypotension is low blood pressure, especially in the arteries of the systemic circulation.
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Inotrope
An inotrope is an agent that alters the force or energy of muscular contractions.
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Insomnia
Insomnia, also known as sleeplessness, is a sleep disorder where people have trouble sleeping.
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Jaundice
Jaundice, also known as icterus, is a yellowish or greenish pigmentation of the skin and whites of the eyes due to high bilirubin levels.
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Kidney disease
Kidney disease, or renal disease, also known as nephropathy, is damage to or disease of a kidney.
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L-type calcium channel
The L-type calcium channel (also known as the dihydropyridine channel, or DHP channel) is part of the high-voltage activated family of voltage-dependent calcium channel.
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Lipid-lowering agent
Hypolipidemic agents, or antihyperlipidemic agents, are a diverse group of pharmaceuticals that are used in the treatment of high levels of fats (lipids), such as cholesterol, in the blood (hyperlipidemia).
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Liver
The liver, an organ only found in vertebrates, detoxifies various metabolites, synthesizes proteins, and produces biochemicals necessary for digestion.
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Major depressive disorder
Major depressive disorder (MDD), also known simply as depression, is a mental disorder characterized by at least two weeks of low mood that is present across most situations.
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Maleic acid
Maleic acid or cis-butenedioic acid is an organic compound that is a dicarboxylic acid, a molecule with two carboxyl groups.
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Mesylate
In chemistry, a mesylate is any salt or ester of methanesulfonic acid (CH3SO3H).
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Mineralocorticoid receptor
The mineralocorticoid receptor (or MR, MLR, MCR), also known as the aldosterone receptor or nuclear receptor subfamily 3, group C, member 2, (NR3C2) is a protein that in humans is encoded by the NR3C2 gene that is located on chromosome 4q31.1-31.2.
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Mitral insufficiency
Mitral insufficiency (MI), mitral regurgitation or mitral incompetence is a disorder of the heart in which the mitral valve does not close properly when the heart pumps out blood.
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Myocardial infarction
Myocardial infarction (MI), commonly known as a heart attack, occurs when blood flow decreases or stops to a part of the heart, causing damage to the heart muscle.
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Myopathy
Myopathy is a disease of the muscle in which the muscle fibers do not function properly.
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Nausea
Nausea or queasiness is an unpleasant sense of unease, discomfort, and revulsion towards food.
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Olmesartan
Olmesartan medoxomil is an angiotensin II receptor antagonist which is used for the treatment of high blood pressure.
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Oral administration
| name.
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Palpitations
Palpitations are the perceived abnormality of the heartbeat characterized by awareness of cardiac muscle contractions in the chest: hard, fast and/or irregular beats.
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Patent
A patent is a set of exclusive rights granted by a sovereign state or intergovernmental organization to an inventor or assignee for a limited period of time in exchange for detailed public disclosure of an invention.
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Perindopril
Perindopril is a long-acting ACE inhibitor used to treat high blood pressure, heart failure, or stable coronary artery disease in form of perindopril arginine (trade names include Coversyl, Coversum) or perindopril erbumine (Aceon).
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Peripheral edema
Peripheral edema is edema (accumulation of fluid causing swelling) in tissues perfused by the peripheral vascular system, usually in the lower limbs.
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Peripheral neuropathy
Peripheral neuropathy (PN) is damage to or disease affecting nerves, which may impair sensation, movement, gland or organ function, or other aspects of health, depending on the type of nerve affected.
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Pfizer
Pfizer Inc. is an American pharmaceutical conglomerate headquartered in New York City, with its research headquarters in Groton, Connecticut.
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Pharmacodynamics
Pharmacodynamics is the study of the biochemical and physiologic effects of drugs (especially pharmaceutical drugs).
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Pregnancy
Pregnancy, also known as gestation, is the time during which one or more offspring develops inside a woman.
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Pulmonary edema
Pulmonary edema is fluid accumulation in the tissue and air spaces of the lungs.
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Pyridine
Pyridine is a basic heterocyclic organic compound with the chemical formula C5H5N.
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Racemic mixture
In chemistry, a racemic mixture, or racemate, is one that has equal amounts of left- and right-handed enantiomers of a chiral molecule.
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Rate pressure product
Pressure rate product, also known as Cardiovascular Product or Double Product, is used in cardiology and exercise physiology to determine the myocardial workload.
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Receptor antagonist
A receptor antagonist is a type of receptor ligand or drug that blocks or dampens a biological response by binding to and blocking a receptor rather than activating it like an agonist.
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Renin
Renin (etymology and pronunciation), also known as an angiotensinogenase, is an aspartic protease protein and enzyme secreted by the kidneys that participates in the body's renin–angiotensin–aldosterone system (RAAS)—also known as the renin–angiotensin–aldosterone axis—that mediates the volume of extracellular fluid (blood plasma, lymph and interstitial fluid), and arterial vasoconstriction.
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Renin inhibitor
Renin inhibitors are a group of pharmaceutical drugs used primarily in treatment of essential hypertension (high blood pressure).
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Renin–angiotensin system
The renin–angiotensin system (RAS) or the renin–angiotensin–aldosterone system (RAAS) is a hormone system that regulates blood pressure and fluid balance.
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Serotonin
Serotonin or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter.
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Sildenafil
Sildenafil, sold as the brand name Viagra among others, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension.
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Simvastatin
Simvastatin, marketed under the trade name Zocor among others, is a lipid-lowering medication.
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Somnolence
Somnolence (alternatively "sleepiness" or "drowsiness") is a state of strong desire for sleep, or sleeping for unusually long periods (compare hypersomnia).
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Tachycardia
Tachycardia, also called tachyarrhythmia, is a heart rate that exceeds the normal resting rate.
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Tacrolimus
No description.
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Telmisartan
Telmisartan (INN) is an angiotensin II receptor antagonist (angiotensin receptor blocker, ARB) used in the management of hypertension.
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Thromboxane A2
Thromboxane A2 (TXA2) is a type of thromboxane that is produced by activated platelets and has prothrombotic properties: it stimulates activation of new platelets as well as increases platelet aggregation.
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Urine
Urine is a liquid by-product of metabolism in humans and in many animals.
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Valsartan
Valsartan (trade name Diovan) is mainly used for treatment of high blood pressure, congestive heart failure, and to increase the chances of living longer after a heart attack.
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Variant angina
Variant angina, often termed Prinzmetal's angina, Prinzmetal angina, and less commonly vasospastic angina, angina inversa, coronary vessel spasm, or coronary artery vasospasm, is a syndrome typically consisting of angina (cardiac chest pain) that unlike classical angina, which is triggered by exertion or exercise, commonly occurs in individuals at rest or even asleep.
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Vascular resistance
Vascular resistance is the resistance that must be overcome to push blood through the circulatory system and create flow.
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Vascular smooth muscle
Vascular smooth muscle refers to the particular type of smooth muscle found within, and composing the majority of the wall of blood vessels.
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Vasodilation
Vasodilation is the widening of blood vessels.
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Vasospasm
Vasospasm refers to a condition in which an arterial spasm leads to vasoconstriction.
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Ventricle (heart)
A ventricle is one of two large chambers in the heart that collect and expel blood received from an atrium towards the peripheral beds within the body and lungs.
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Ventricular septal defect
A ventricular septal defect (VSD) is a defect in the ventricular septum, the wall dividing the left and right ventricles of the heart.
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WHO Model List of Essential Medicines
The WHO Model List of Essential Medicines (EML), published by the World Health Organization (WHO), contains the medications considered to be most effective and safe to meet the most important needs in a health system.
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Zona glomerulosa
The zona glomerulosa of the adrenal gland is the most superficial layer of the adrenal cortex, lying directly beneath the renal capsule.
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Redirects here:
ATC code C08CA01, ATCvet code QC08CA01, Amlocard, Amlodin, Amlodipine besylate, Amlodipine maleate, Amlodis, Amlodopine, Amloratio, Amvaz, Coroval, Lipinox, Norvasc.
References
[1] https://en.wikipedia.org/wiki/Amlodipine