49 relations: Adolf Butenandt, Allosteric modulator, Androgen, Androstane, Androstanediol, Androstanedione, Androstenedione, Androstenol, Androsterone glucuronide, Androsterone sulfate, Animal, Anticonvulsant, Axilla, Biotransformation, Dihydrotestosterone, Endogeny (biology), Epiandrosterone, Epietiocholanolone, Epimer, Estrone, Etiocholanolone, Excretion, GABAA receptor, Glucuronidation, Inhibitory postsynaptic potential, Isomer, List of androgens/anabolic steroids, Metabolic intermediate, Metabolite, Neurosteroid, Pheromone, Pine, Pollen, Potency (pharmacology), Sebaceous gland, Skin, Species, Steroid hormone, Sulfation, Testosterone, Testosterone (medication), Urine, 17β-Hydroxysteroid dehydrogenase, 3α-Androstanediol, 3α-Hydroxysteroid dehydrogenase, 3β-Hydroxysteroid dehydrogenase, 5α-Reductase, 5β-Dihydrotestosterone, 5β-Reductase.
Adolf Friedrich Johann Butenandt (24 March 1903 – 18 January 1995) was a German biochemist.
In biochemistry and pharmacology, an allosteric modulator (allo- from the Greek meaning "other") is a substance which indirectly influences (modulates) the effects of a primary ligand that directly activates or deactivates the function of a target protein.
An androgen (from Greek andr-, the stem of the word meaning "man") is any natural or synthetic steroid hormone which regulates the development and maintenance of male characteristics in vertebrates by binding to androgen receptors.
Androstane is a C19 steroid with a gonane core.
Androstanediol may refer to.
Androstanediones are a pair of isomeric steroids which differ at the 5-position.
Androstenedione, or 4-androstenedione (abbreviated as A4 or Δ4-dione), also known as androst-4-ene-3,17-dione, is an endogenous weak androgen steroid hormone and intermediate in the biosynthesis of estrone and of testosterone from dehydroepiandrosterone (DHEA).
Androstenol, also known as 5α-androst-16-en-3α-ol (shortened to 3α,5α-androstenol or 3α-androstenol), is a steroidal pheromone and neurosteroid in humans and other mammals, notably pigs.
Androsterone glucuronide (ADT-G) is a major circulating and urinary metabolite of testosterone and dihydrotestosterone (DHT).
Androsterone sulfate, also known as 3α-hydroxy-5α-androstan-17-one 3α-sulfate, is an endogenous, naturally occurring steroid and one of the major urinary metabolites of androgens.
Animals are multicellular eukaryotic organisms that form the biological kingdom Animalia.
Anticonvulsants (also commonly known as antiepileptic drugs or as antiseizure drugs) are a diverse group of pharmacological agents used in the treatment of epileptic seizures.
The axilla (also, armpit, underarm or oxter) is the area on the human body directly under the joint where the arm connects to the shoulder.
Biotransformation is the chemical modification (or modifications) made by an organism on a chemical compound.
Dihydrotestosterone (DHT), or 5α-dihydrotestosterone (5α-DHT), also known as androstanolone or stanolone, is an endogenous androgen sex steroid and hormone.
Endogenous substances and processes are those that originate from within an organism, tissue, or cell.
Epiandrosterone, or isoandrosterone, also known as 3β-androsterone, 3β-hydroxy-5α-androstan-17-one, or 5α-androstan-3β-ol-17-one, is a steroid hormone with weak androgenic activity.
Epietiocholanolone, also known as 5β-androstan-3β-ol-17-one or as etiocholan-3β-ol-17-one, is an etiocholane (5β-androstane) steroid as well as an inactive metabolite of testosterone that is formed in the liver.
In stereochemistry, an epimer is one of a pair of stereoisomers.
Estrone (E1), also spelled oestrone, is a steroid, a weak estrogen, and a minor female sex hormone.
Etiocholanolone, also known as 5β-androsterone, as well as 3α-hydroxy-5β-androstan-17-one or etiocholan-3α-ol-17-one, is an etiocholane (5β-androstane) steroid as well as an endogenous 17-ketosteroid that is produced from the metabolism of testosterone.
Excretion is the process by which metabolic waste is eliminated from an organism.
The GABAA receptor (GABAAR) is an ionotropic receptor and ligand-gated ion channel.
Glucuronidation is often involved in drug metabolism of substances such as drugs, pollutants, bilirubin, androgens, estrogens, mineralocorticoids, glucocorticoids, fatty acid derivatives, retinoids, and bile acids.
An inhibitory postsynaptic potential (IPSP) is a kind of synaptic potential that makes a postsynaptic neuron less likely to generate an action potential.
An isomer (from Greek ἰσομερής, isomerès; isos.
This is a list of androgens/anabolic steroids (AAS) or testosterone derivatives.
Metabolic intermediates are molecules which are the precursors or metabolites of biologically significant molecules.
A metabolite is the intermediate end product of metabolism.
Neurosteroids, also known as neuroactive steroids, are endogenous or exogenous steroids that rapidly alter neuronal excitability through interaction with ligand-gated ion channels and other cell surface receptors.
A pheromone (from Ancient Greek φέρω phero "to bear" and hormone, from Ancient Greek ὁρμή "impetus") is a secreted or excreted chemical factor that triggers a social response in members of the same species.
A pine is any conifer in the genus Pinus,, of the family Pinaceae.
Pollen is a fine to coarse powdery substance comprising pollen grains which are male microgametophytes of seed plants, which produce male gametes (sperm cells).
In the field of pharmacology, potency is a measure of drug activity expressed in terms of the amount required to produce an effect of given intensity.
Sebaceous glands are microscopic exocrine glands in the skin that secrete an oily or waxy matter, called sebum, to lubricate and waterproof the skin and hair of mammals.
Skin is the soft outer tissue covering vertebrates.
In biology, a species is the basic unit of classification and a taxonomic rank, as well as a unit of biodiversity, but it has proven difficult to find a satisfactory definition.
A steroid hormone is a steroid that acts as a hormone.
Sulfation or sulfurylation (not to be confused with sulfonation) in biochemistry is the enzyme-catalyzed conjugation of a sulfo group (not a sulfate or sulfuryl group) to another molecule.
Testosterone is the primary male sex hormone and an anabolic steroid.
Testosterone is a medication and naturally occurring steroid hormone.
Urine is a liquid by-product of metabolism in humans and in many animals.
17β-Hydroxysteroid dehydrogenases (17β-HSD, HSD17B), also 17-ketosteroid reductases (17-KSR), are a group of alcohol oxidoreductases which catalyze the reduction of 17-ketosteroids and the dehydrogenation of 17β-hydroxysteroids in steroidogenesis and steroid metabolism.
3α-Androstanediol (often abbreviated as 3α-diol), also known as 5α-androstane-3α,17β-diol, is an endogenous inhibitory androstane neurosteroid and weak androgen, and a major metabolite of dihydrotestosterone (DHT).
3α-hydroxysteroid dehydrogenase (3α-HSD), also known as aldo-keto reductase family 1 member C4, is an enzyme that in humans is encoded by the AKR1C4 gene.
3β-Hydroxysteroid dehydrogenase/Δ5-4 isomerase (3β-HSD) is an enzyme that catalyzes the biosynthesis of progesterone from pregnenolone, 17α-hydroxyprogesterone from 17α-hydroxypregnenolone, and androstenedione from dehydroepiandrosterone (DHEA) in the adrenal gland.
5α-reductases, also known as 3-oxo-5α-steroid 4-dehydrogenases, are enzymes involved in steroid metabolism.
5β-Dihydrotestosterone (5β-DHT), also known as 5β-androstan-17β-ol-3-one or as etiocholan-17β-ol-3-one, is an etiocholane (5β-androstane) steroid as well as an inactive metabolite of testosterone formed by 5β-reductase in the liver and bone marrow and an intermediate in the formation of 3α,5β-androstanediol and 3β,5β-androstanediol (by 3α- and 3β-hydroxysteroid dehydrogenase) and, from them, respectively, etiocholanolone and epietiocholanolone (by 17β-hydroxysteroid dehydrogenase).
5β-Reductase, or Δ4-3-oxosteroid 5β-reductase (3-oxo-Δ4-steroid 5β-reductase, androstenedione 5β-reductase, cholestenone 5β-reductase, cortisone 5β-reductase, cortisone Δ4-5β-reductase, steroid 5β-reductase, testosterone 5β-reductase, Δ4-3-ketosteroid 5β-reductase, Δ4-5β-reductase, Δ4-hydrogenase, 4,5β-dihydrocortisone:NADP+ Δ4-oxidoreductase, 3-oxo-5β-steroid:NADP+ Δ4-oxidoreductase) is an enzyme with systematic name 5β-cholestan-3-one:NADP+ 4,5-oxidoreductase.