110 relations: Aerobic exercise, Alpha-5 beta-1, Alpha-v beta-3, Alpha-v beta-5, Angioblast, Angiogenesis inhibitor, Angiopoietin, Angiopoietin 1, Angiopoietin receptor, ANGPT2, Arteriogenesis, Basement membrane, Basic fibroblast growth factor, Beta-catenin, Bilayer, Blood vessel, Cancer, Capillary, CCL2, CD31, Cell (biology), Cell growth, Cell junction, Cell signaling, CGMP-dependent protein kinase, Circulating tumor cell, Circulatory system, Collagen, Concentration, De novo synthesis, Diet (nutrition), DLL4, Edema, Embryo, Endoglin, Endothelium, Endurance training, Enzyme, Ephrin, Extracellular matrix, FGF1, Fibroblast growth factor, Gene knockout, Granulation tissue, Growth factor, Histamine, Hyperaemia, ID1, ID3 (gene), Infant, ..., Inflammation, Integrin, Ischemia, Judah Folkman, Lumen (anatomy), Lymphocyte, Macular degeneration, Malignancy, Matrix (biology), Matrix metalloproteinase, Mechanism of action, Medication, Mesoderm, Messenger RNA, Metastasis, Microcirculation, Mutation, Myofibroblast, Neoplasm, Neovascularization, Neuroangiogenesis, Neuropilin, Neuropilin 1, Nitric oxide synthase, Notch signaling pathway, Oxygen, Perforation, Perfusion, Pericyte, Phosphorylation, Plasminogen activator, Plasminogen activator inhibitor-1, Platelet-derived growth factor, Platelet-derived growth factor receptor, Presentation, Prostaglandin-endoperoxide synthase 2, Protease, Proteases in angiogenesis, Random42, Receptor (biochemistry), Semaphorin, Smooth muscle tissue, Space, Tandem, TGF beta receptor, The Angiogenesis Foundation, The Proteolysis Map, TIE1, Time, Transdifferentiation, Transforming growth factor beta, Tyrosine kinase, Usage, Vascular endothelial growth factor, Vasculogenesis, Vasculogenic mimicry, VE-cadherin, VEGF receptor, Western world, Wound healing. Expand index (60 more) » « Shrink index
Aerobic exercise (also known as cardio) is physical exercise of low to high intensity that depends primarily on the aerobic energy-generating process.
α5β1 is an integrin that binds to matrix macromolecules and proteinases and thereby stimulates angiogenesis.
αVβ3 is a type of integrin that is a receptor for vitronectin.
αVβ5 is a type of integrin that binds to matrix macromolecules and proteinases and thereby stimulates angiogenesis.
Angioblast (or vasoformative cell) is the embryonic tissue from which blood vessels arise.
An angiogenesis inhibitor is a substance that inhibits the growth of new blood vessels (angiogenesis).
Angiopoietin is part of a family of vascular growth factors that play a role in embryonic and postnatal angiogenesis.
Angiopoietin 1 is a type of angiopoietin and is encoded by the gene ANGPT1.
The angiopoietin receptors are receptors that bind angiopoietin.
Angiopoietin-2 is a protein that in humans is encoded by the ANGPT2 gene.
Arteriogenesis refers to an increase in the diameter of existing arterial vessels.
The basement membrane is a thin, fibrous, extracellular matrix of tissue that separates the lining of an internal or external body surface from underlying connective tissue in metazoans.
FGF2, also known as basic fibroblast growth factor (bFGF) and FGF-β, is a growth factor and signaling protein encoded by the FGF2 gene.
Catenin beta-1, also known as β-catenin, is a protein that in humans is encoded by the CTNNB1 gene.
A bilayer is a double layer of closely packed atoms or molecules.
The blood vessels are the part of the circulatory system, and microcirculation, that transports blood throughout the human body.
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.
A capillary is a small blood vessel from 5 to 10 micrometres (µm) in diameter, and having a wall one endothelial cell thick.
For the ICAO airport code see Candle Lake Airpark, for the diradical compound see Dichlorocarbene. The chemokine (C-C motif) ligand 2 (CCL2) is also referred to as monocyte chemoattractant protein 1 (MCP1) and small inducible cytokine A2.
Platelet endothelial cell adhesion molecule (PECAM-1) also known as cluster of differentiation 31 (CD31) is a protein that in humans is encoded by the PECAM1 gene found on chromosome 17.
The cell (from Latin cella, meaning "small room") is the basic structural, functional, and biological unit of all known living organisms.
The term cell growth is used in the contexts of biological cell development and cell division (reproduction).
A cell junction (or intercellular bridge) is a type of structure that exists within the tissue of some multicellular organisms, such as animals.
Cell signaling (cell signalling in British English) is part of any communication process that governs basic activities of cells and coordinates all cell actions.
cGMP-dependent protein kinase or Protein Kinase G (PKG) is a serine/threonine-specific protein kinase that is activated by cGMP.
Circulating tumor cells (CTCs) are cells that have shed into the vasculature or lymphatics from a primary tumor and are carried around the body in the blood circulation.
The circulatory system, also called the cardiovascular system or the vascular system, is an organ system that permits blood to circulate and transport nutrients (such as amino acids and electrolytes), oxygen, carbon dioxide, hormones, and blood cells to and from the cells in the body to provide nourishment and help in fighting diseases, stabilize temperature and pH, and maintain homeostasis.
Collagen is the main structural protein in the extracellular space in the various connective tissues in animal bodies.
In chemistry, concentration is the abundance of a constituent divided by the total volume of a mixture.
De novo synthesis refers to the synthesis of complex molecules from simple molecules such as sugars or amino acids, as opposed to recycling after partial degradation.
In nutrition, diet is the sum of food consumed by a person or other organism.
Delta-like 4 is a protein that in humans is encoded by the DLL4 gene.
Edema, also spelled oedema or œdema, is an abnormal accumulation of fluid in the interstitium, located beneath the skin and in the cavities of the body, which can cause severe pain.
An embryo is an early stage of development of a multicellular diploid eukaryotic organism.
Endoglin (ENG) is a type I membrane glycoprotein located on cell surfaces and is part of the TGF beta receptor complex.
Endothelium refers to cells that line the interior surface of blood vessels and lymphatic vessels, forming an interface between circulating blood or lymph in the lumen and the rest of the vessel wall.
Endurance training is the act of exercising to increase endurance.
Enzymes are macromolecular biological catalysts.
Ephrins (also known as ephrin ligands or Eph family receptor interacting proteins) are a family of proteins that serve as the ligands of the eph receptor.
In biology, the extracellular matrix (ECM) is a collection of extracellular molecules secreted by support cells that provides structural and biochemical support to the surrounding cells.
FGF1, also known as acidic fibroblast growth factor (aFGF), is a growth factor and signaling protein encoded by the FGF1 gene.
The fibroblast growth factors are a family of cell signalling proteins that are involved in a wide variety of processes, most notably as crucial elements for normal development.
A gene knockout (abbreviation: KO) is a genetic technique in which one of an organism's genes is made inoperative ("knocked out" of the organism).
Granulation tissue is new connective tissue and microscopic blood vessels that form on the surfaces of a wound during the healing process.
A growth factor is a naturally occurring substance capable of stimulating cellular growth, proliferation, healing, and cellular differentiation.
Histamine is an organic nitrogenous compound involved in local immune responses, as well as regulating physiological function in the gut and acting as a neurotransmitter for the brain, spinal cord, and uterus.
Hyperemia, hyperæmia, or hyperaemia (Greek ὑπέρ (hupér, "over") + αἷμα (haîma, “blood”)) is the increase of blood flow to different tissues in the body.
DNA-binding protein inhibitor ID-1 is a protein that in humans is encoded by the ID1 gene.
DNA-binding protein inhibitor ID-3 is a protein that in humans is encoded by the ID3 gene.
An infant (from the Latin word infans, meaning "unable to speak" or "speechless") is the more formal or specialised synonym for "baby", the very young offspring of a human.
Inflammation (from inflammatio) is part of the complex biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or irritants, and is a protective response involving immune cells, blood vessels, and molecular mediators.
Integrins are transmembrane receptors that facilitate cell-extracellular matrix (ECM) adhesion.
Ischemia or ischaemia is a restriction in blood supply to tissues, causing a shortage of oxygen that is needed for cellular metabolism (to keep tissue alive).
Moses Judah Folkman (February 24, 1933 – January 14, 2008) was an American medical scientist best known for his research on tumor angiogenesis, the process by which a tumor attracts blood vessels to nourish itself and sustain its existence.
In biology, a lumen (plural lumina) is the inside space of a tubular structure, such as an artery or intestine.
A lymphocyte is one of the subtypes of white blood cell in a vertebrate's immune system.
Macular degeneration, also known as age-related macular degeneration (AMD or ARMD), is a medical condition which may result in blurred or no vision in the center of the visual field.
Malignancy is the tendency of a medical condition to become progressively worse.
In biology, matrix (plural: matrices) is the material (or tissue) in animal or plant cells, in which more specialized structures are embedded, and a specific part of the mitochondrion.
Matrix metalloproteinases (MMPs), also known as matrixins, are calcium-dependent zinc-containing endopeptidases; other family members are adamalysins, serralysins, and astacins.
In pharmacology, the term mechanism of action (MOA) refers to the specific biochemical interaction through which a drug substance produces its pharmacological effect.
A medication (also referred to as medicine, pharmaceutical drug, or simply drug) is a drug used to diagnose, cure, treat, or prevent disease.
In all bilaterian animals, the mesoderm is one of the three primary germ layers in the very early embryo.
Messenger RNA (mRNA) is a large family of RNA molecules that convey genetic information from DNA to the ribosome, where they specify the amino acid sequence of the protein products of gene expression.
Metastasis is a pathogenic agent's spread from an initial or primary site to a different or secondary site within the host's body; it is typically spoken of as such spread by a cancerous tumor.
Microcirculation is the circulation of the blood in the smallest blood vessels, present within organ tissues.
In biology, a mutation is the permanent alteration of the nucleotide sequence of the genome of an organism, virus, or extrachromosomal DNA or other genetic elements.
A myofibroblast is a cell that is in between a fibroblast and a smooth muscle cell in phenotype.
Neoplasia is a type of abnormal and excessive growth of tissue.
Neovascularization is the natural formation of new blood vessels (neo- + vascular + -ization), usually in the form of functional microvascular networks, capable of perfusion by red blood cells, that form to serve as collateral circulation in response to local poor perfusion or ischemia.
Neuroangiogenesis is a term used to describe the coordinated growth of nerves and blood vessels.
Neuropilin is a protein receptor active in neurons.
Neuropilin-1 is a protein that in humans is encoded by the NRP1 gene.
Nitric oxide synthases (NOSs) are a family of enzymes catalyzing the production of nitric oxide (NO) from L-arginine.
The Notch signaling pathway is a highly conserved cell signaling system present in most multicellular organisms.
Oxygen is a chemical element with symbol O and atomic number 8.
A perforation is a small hole in a thin material or web.
Perfusion is the passage of fluid through the circulatory system or lymphatic system to an organ or a tissue, usually referring to the delivery of blood to a capillary bed in tissue.
Pericytes are contractile cells that wrap around the endothelial cells that line the capillaries and venules throughout the body.
In chemistry, phosphorylation of a molecule is the attachment of a phosphoryl group.
Plasminogen activators are serine proteases that catalyze the activation of plasmin via proteolytic cleavage of its zymogen form plasminogen.
Plasminogen activator inhibitor-1 (PAI-1) also known as endothelial plasminogen activator inhibitor or serpin E1 is a protein that in humans is encoded by the SERPINE1 gene.
Platelet-derived growth factor (PDGF) is one of numerous growth factors that regulate cell growth and division.
Platelet-derived growth factor receptors (PDGF-R) are cell surface tyrosine kinase receptors for members of the platelet-derived growth factor (PDGF) family.
A presentation is the process of presenting a topic to an audience.
Prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (The HUGO official symbol is PTGS2; HGNC ID, HGNC:9605), also known as cyclooxygenase-2 or COX-2, is an enzyme that in humans is encoded by the PTGS2 gene.
A protease (also called a peptidase or proteinase) is an enzyme that performs proteolysis: protein catabolism by hydrolysis of peptide bonds.
Angiogenesis is the process of forming new blood vessels from existing blood vessels.
Random42 is a medical animation studio based in central London.
In biochemistry and pharmacology, a receptor is a protein molecule that receives chemical signals from outside a cell.
Semaphorins are a class of secreted and membrane proteins that were originally identified as axonal growth cone guidance molecules.
Smooth muscle is an involuntary non-striated muscle.
Space is the boundless three-dimensional extent in which objects and events have relative position and direction.
Tandem, or in tandem, is an arrangement in which a team of machines, animals or people are lined up one behind another, all facing in the same direction.
Transforming growth factor beta (TGFβ) receptors are single pass serine/threonine kinase receptors.
The Angiogenesis Foundation, is a United States 501(c)(3) nonprofit organization established in 1994 for the study of angiogenesis.
The Proteolysis MAP (PMAP) is an integrated web resource focused on proteases.
Tyrosine kinase with immunoglobulin-like and EGF-like domains 1 also known as TIE1 is an angiopoietin receptor which in humans is encoded by the TIE1 gene.
Time is the indefinite continued progress of existence and events that occur in apparently irreversible succession from the past through the present to the future.
Transdifferentiation, also known as lineage reprogramming, is a process in which one mature somatic cell transforms into another mature somatic cell without undergoing an intermediate pluripotent state or progenitor cell type.
Transforming growth factor beta (TGF-β) is a multifunctional cytokine belonging to the transforming growth factor superfamily that includes four different isoforms (TGF-β 1 to 4, HGNC symbols TGFB1, TGFB2, TGFB3, TGFB4) and many other signaling proteins produced by all white blood cell lineages.
A tyrosine kinase is an enzyme that can transfer a phosphate group from ATP to a protein in a cell.
Usage is the manner in which written and spoken language is used, the "points of grammar, syntax, style, and the choice of words", and "the way in which a word or phrase is normally and correctly used".
Vascular endothelial growth factor (VEGF), originally known as vascular permeability factor (VPF), is a signal protein produced by cells that stimulates the formation of blood vessels.
Vasculogenesis is the process of blood vessel formation occurring by a de novo production of endothelial cells.
Vasculogenic mimicry is the formation of microvascular channels by aggressive, metastatic and genetically deregulated tumour cells.
Cadherin 5, type 2 or VE-cadherin (vascular endothelial cadherin) also known as CD144 ('''C'''luster of '''D'''ifferentiation 144), is a type of cadherin.
VEGF receptors are receptors for vascular endothelial growth factor (VEGF).
The Western world refers to various nations depending on the context, most often including at least part of Europe and the Americas.
Wound healing is an intricate process in which the skin repairs itself after injury.
Angiogenesis assays, Angiogenesis modulating agents, Angiogenic, Angiogenic protein, Angiogenic proteins, Antiogenesis, Capillary sprout, Capillary sprouts, Neoangiogenesis, Vascularisation, Vascularization, Vascularized.