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Anterior segment mesenchymal dysgenesis

Index Anterior segment mesenchymal dysgenesis

Anterior segment mesenchymal dysgenesis, or simply anterior segment dysgenesis (ASD), is a failure of the normal development of the tissues of the anterior segment of the eye. [1]

20 relations: Anterior chamber of eyeball, Anterior segment of eyeball, Autism spectrum, Cornea, Corneal endothelium, Descemet's membrane, Dominance (genetics), Forkhead box C1, Gene dosage, Glaucoma, Iris (anatomy), Lens (anatomy), Mesenchymal stem cell, Mesenchyme, Neural crest, Optic cup (embryology), PITX2, Regulation of gene expression, Stroma of cornea, Transcription factor.

Anterior chamber of eyeball

The anterior chamber (AC) is the fluid-filled space inside the eye between the iris and the cornea's innermost surface, the endothelium.

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Anterior segment of eyeball

The anterior segment or anterior cavity is the front third of the eye that includes the structures in front of the vitreous humour: the cornea, iris, ciliary body, and lens.

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Autism spectrum

Autism spectrum, also known as autism spectrum disorder (ASD), is a range of conditions classified as neurodevelopmental disorders.

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Cornea

The cornea is the transparent front part of the eye that covers the iris, pupil, and anterior chamber.

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Corneal endothelium

The corneal endothelium is a single layer of cells on the inner surface of the cornea.

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Descemet's membrane

Descemet's membrane (or the Descemet membrane) is the basement membrane that lies between the corneal proper substance, also called stroma, and the endothelial layer of the cornea.

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Dominance (genetics)

Dominance in genetics is a relationship between alleles of one gene, in which the effect on phenotype of one allele masks the contribution of a second allele at the same locus.

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Forkhead box C1

Forkhead box C1, also known as FOXC1, is a protein which in humans is encoded by the FOXC1 gene.

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Gene dosage

Gene dosage is the number of copies of a particular gene present in a genome.

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Glaucoma

Glaucoma is a group of eye diseases which result in damage to the optic nerve and vision loss.

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Iris (anatomy)

In humans and most mammals and birds, the iris (plural: irides or irises) is a thin, circular structure in the eye, responsible for controlling the diameter and size of the pupil and thus the amount of light reaching the retina.

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Lens (anatomy)

The lens is a transparent, biconvex structure in the eye that, along with the cornea, helps to refract light to be focused on the retina.

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Mesenchymal stem cell

Mesenchymal stem cells are multipotent stromal cells that can differentiate into a variety of cell types, including osteoblasts (bone cells), chondrocytes (cartilage cells), myocytes (muscle cells) and adipocytes (fat cells which give rise to marrow adipose tissue).

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Mesenchyme

Mesenchyme, in vertebrate embryology, is a type of connective tissue found mostly during the development of the embryo.

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Neural crest

Neural crest cells are a temporary group of cells unique to chordates of the group Cristozoa that arise from the embryonic ectoderm cell layer, and in turn give rise to a diverse cell lineage—including melanocytes, craniofacial cartilage and bone, smooth muscle, peripheral and enteric neurons and glia.

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Optic cup (embryology)

During embryonic development of the eye, the outer wall of the bulb of the optic vesicles becomes thickened and invaginated, and the bulb is thus converted into a cup, the optic cup (or ophthalmic cup), consisting of two strata of cells.

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PITX2

Paired-like homeodomain transcription factor 2 also known as pituitary homeobox 2 is a protein that in humans is encoded by the PITX2 gene.

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Regulation of gene expression

Regulation of gene expression includes a wide range of mechanisms that are used by cells to increase or decrease the production of specific gene products (protein or RNA), and is informally termed gene regulation.

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Stroma of cornea

The substantia propria (or stroma of cornea) is fibrous, tough, unyielding, and perfectly transparent.

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Transcription factor

In molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription of genetic information from DNA to messenger RNA, by binding to a specific DNA sequence.

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Redirects here:

Anterior Segment Dysgenesis, Anterior chamber cleavage syndrome, Anterior segment dysgenesis, Mesodermal dysgenesis of cornea, Peter's anomaly, Peters anomaly, Peters' anomaly.

References

[1] https://en.wikipedia.org/wiki/Anterior_segment_mesenchymal_dysgenesis

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