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36 relations: Abciximab, Adenosine diphosphate receptor inhibitor, Adenosine reuptake inhibitor, Anticoagulant, Artery, Aspirin, Chemotherapy, Cilostazol, Clopidogrel, Dipyridamole, Eptifibatide, Glycoprotein IIb/IIIa inhibitors, Haemophilia, Hemostasis, Immune thrombocytopenic purpura, Kidney failure, Liver disease, Nitrophorin, P2Y receptor, Pharmacology, Phosphodiesterase inhibitor, Placebo, Platelet, Prasugrel, Terutroban, Thrombolysis, Thromboxane, Thromboxane receptor, Thromboxane-A synthase, Thrombus, Ticagrelor, Ticlopidine, Tirofiban, Triflusal, Von Willebrand disease, Vorapaxar.
Abciximab
Abciximab (previously known as c7E3 Fab), a glycoprotein IIb/IIIa receptor antagonist manufactured by Janssen Biologics BV and distributed by Eli Lilly under the trade name ReoPro, is a platelet aggregation inhibitor mainly used during and after coronary artery procedures like angioplasty to prevent platelets from sticking together and causing thrombus (blood clot) formation within the coronary artery.
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Adenosine diphosphate receptor inhibitor
Adenosine diphosphate (ADP) receptor inhibitors are a drug class of antiplatelet agents, used in the treatment of acute coronary syndrome (ACS) or in preventive treatment for patients who are in risk of thromboembolism, myocardial infarction or a stroke.
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Adenosine reuptake inhibitor
An adenosine reuptake inhibitor (AdoRI) is a type of drug which acts as a reuptake inhibitor for the purine nucleoside and neurotransmitter adenosine by blocking the action of one or more of the equilibrative nucleoside transporters (ENTs).
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Anticoagulant
Anticoagulants, commonly referred to as blood thinners, are chemical substances that prevent or reduce coagulation of blood, prolonging the clotting time.
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Artery
An artery (plural arteries) is a blood vessel that takes blood away from the heart to all parts of the body (tissues, lungs, etc).
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Aspirin
Aspirin, also known as acetylsalicylic acid (ASA), is a medication used to treat pain, fever, or inflammation.
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Chemotherapy
Chemotherapy (often abbreviated to chemo and sometimes CTX or CTx) is a type of cancer treatment that uses one or more anti-cancer drugs (chemotherapeutic agents) as part of a standardized chemotherapy regimen.
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Cilostazol
Cilostazol is a quinolinone-derivative medication used in the alleviation of the symptoms of intermittent claudication in individuals with peripheral vascular disease.
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Clopidogrel
Clopidogrel, sold as the brandname Plavix among others, is an antiplatelet medication that is used to reduce the risk of heart disease and stroke in those at high risk.
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Dipyridamole
Dipyridamole (trademarked as Persantine and others) is a medication that inhibits blood clot formation when given chronically and causes blood vessel dilation when given at high doses over a short time.
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Eptifibatide
Eptifibatide (Integrilin, Millennium Pharmaceuticals, also co-promoted by Schering-Plough/Essex), is an antiplatelet drug of the glycoprotein IIb/IIIa inhibitor class.
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Glycoprotein IIb/IIIa inhibitors
In medicine, glycoprotein IIb/IIIa inhibitors, also GpIIb/IIIa inhibitors, is a class of antiplatelet agents.
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Haemophilia
Haemophilia, also spelled hemophilia, is a mostly inherited genetic disorder that impairs the body's ability to make blood clots, a process needed to stop bleeding.
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Hemostasis
Hemostasis or haemostasis is a process which causes bleeding to stop, meaning to keep blood within a damaged blood vessel (the opposite of hemostasis is hemorrhage).
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Immune thrombocytopenic purpura
Immune thrombocytopenia (ITP) is a type of thrombocytopenic purpura defined as isolated low platelet count (thrombocytopenia) with normal bone marrow and the absence of other causes of thrombocytopenia.
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Kidney failure
Kidney failure, also known as end-stage kidney disease, is a medical condition in which the kidneys no longer work.
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Liver disease
Liver disease (also called hepatic disease) is a type of damage to or disease of the liver.
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Nitrophorin
Nitrophorins are hemoproteins found in the saliva of blood-feeding insects.
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P2Y receptor
P2Y receptors are a family of purinergic G protein-coupled receptors, stimulated by nucleotides such as ATP, ADP, UTP, UDP and UDP-glucose.
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Pharmacology
Pharmacology is the branch of biology concerned with the study of drug action, where a drug can be broadly defined as any man-made, natural, or endogenous (from within body) molecule which exerts a biochemical or physiological effect on the cell, tissue, organ, or organism (sometimes the word pharmacon is used as a term to encompass these endogenous and exogenous bioactive species).
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Phosphodiesterase inhibitor
A phosphodiesterase inhibitor is a drug that blocks one or more of the five subtypes of the enzyme phosphodiesterase (PDE), thereby preventing the inactivation of the intracellular second messengers cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP) by the respective PDE subtype(s).
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Placebo
A placebo is a substance or treatment of no intended therapeutic value.
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Platelet
Platelets, also called thrombocytes (from Greek θρόμβος, "clot" and κύτος, "cell"), are a component of blood whose function (along with the coagulation factors) is to react to bleeding from blood vessel injury by clumping, thereby initiating a blood clot.
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Prasugrel
Prasugrel (trade name Effient in the US and India, and Efient in the EU) is a drug used to prevent formation of blood clots.
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Terutroban
Terutroban is an antiplatelet agent developed by Servier Laboratories. It has been tested for the secondary prevention of acute thrombotic complications in the Phase III clinical trial PERFORM (Prevention of cerebrovascular and cardiovascular Events of ischemic origin with teRutroban in patients with a history oF ischemic strOke or tRansient ischeMic attack). The study was prematurely stopped and thus it could not be determined whether terutroban has a better effect than aspirin.
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Thrombolysis
Thrombolysis is the breakdown (lysis) of blood clots formed in blood vessels, using medication.
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Thromboxane
Thromboxane is a member of the family of lipids known as eicosanoids.
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Thromboxane receptor
The thromboxane receptor (TP) also known as the prostanoid TP receptor is a protein that in humans is encoded by the TBXA2R gene, The thromboxane receptor is one among the five classes of prostanoid receptors and was the first eicosanoid receptor cloned.
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Thromboxane-A synthase
Thromboxane A synthase 1 (platelet, cytochrome P450, family 5, subfamily A), also known as TBXAS1, is a cytochrome P450 enzyme that, in humans, is encoded by the TBXAS1 gene.
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Thrombus
A thrombus, colloquially called a blood clot, is the final product of the blood coagulation step in hemostasis.
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Ticagrelor
Ticagrelor (trade name Brilinta, Brilique, and Possia) is a platelet aggregation inhibitor produced by AstraZeneca.
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Ticlopidine
Ticlopidine (trade name Ticlid) is an antiplatelet drug in the thienopyridine family which is an adenosine diphosphate (ADP) receptor inhibitor.
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Tirofiban
Tirofiban (INN, trade name Aggrastat) is an antiplatelet drug.
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Triflusal
Triflusal is a platelet aggregation inhibitor that was discovered and developed in the Uriach Laboratories, and commercialised in Spain since 1981.
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Von Willebrand disease
Von Willebrand disease (vWD) is the most common hereditary blood-clotting disorder in humans.
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Vorapaxar
Vorapaxar (brand name Zontivity, formerly known as SCH 530348) is a thrombin receptor (protease-activated receptor, PAR-1) antagonist based on the natural product himbacine, discovered by Schering-Plough and developed by Merck & Co.
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Anti-platelet, Anti-platelet agent, Anti-platelet drug, Antiaggregant, Antiaggregants, Antiplatelet, Antiplatelet agent, Antiplatelet drugs, Antiplatelet medication, Antiplatelets, Dual antiplatelet therapy, Platelet aggregation inhibitor, Platelet aggregation inhibitors, Platelet inhibitor.
References
[1] https://en.wikipedia.org/wiki/Antiplatelet_drug
