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267 relations: Abiraterone acetate, Acne, Adrenal gland, Adrenal insufficiency, Alfatradiol, Allylestrenol, Alternative splicing, Amenorrhea, Aminoglutethimide, Anabolic steroid, Androgen, Androgen deprivation therapy, Androgen insensitivity syndrome, Androgen receptor, Androgen-dependent condition, Androstenedione, Androvax, Anemia, Antiandrogens in the environment, Antibiotic, Antibody, Antiestrogen, Antigonadotropin, Antimineralocorticoid, Antiprogestogen, Apalutamide, Benign prostatic hyperplasia, Benorterone, Benzoyl peroxide, Bicalutamide, Bifluranol, Bioassay, Biological activity, Biosynthesis, Birth control, Bisphenol A diglycidyl ether, Body fat percentage, Body hair, Body shape, BOMT, Brain, Breast cancer, Breast development, Breast enlargement, Breast pain, Camille G. Wermuth, Castration, Cell division, Cell growth, Cetrorelix, ..., Chemical structure, Chemotherapy, Chlormadinone acetate, Cholesterol, Cholesterol side-chain cleavage enzyme, Cioteronel, Combined oral contraceptive pill, Complete androgen insensitivity syndrome, Congenital adrenal hyperplasia, Conjugated estrogens, Cortexolone 17α-propionate, Covalent bond, Cutaneous condition, CYP17A1 inhibitor, Cyproterone, Cyproterone acetate, Delmadinone acetate, Depression (mood), Dienogest, Diethylstilbestrol, Dihydrotestosterone, Dimethylcurcumin, DIMP (antiandrogen), Downregulation and upregulation, Drospirenone, Drug, Dutasteride, Efficacy, Enzalutamide, Enzyme, Enzyme inhibitor, EPI-001, Epileptic seizure, Epristeride, Erectile dysfunction, Erection, Estradiol (medication), Estradiol undecylate, Estradiol valerate, Estrogen, Estrogen (medication), Ethinylestradiol, Fatigue, Fecundity, Female, Femininity, Feminization (biology), Fertility, Fetus, Finasteride, Flutamide, Follicle-stimulating hormone, Fulvestrant, Function (biology), Gene expression, Gestonorone caproate, Glucocorticoid, Gonad, Gonadotropin, Gonadotropin-releasing hormone, Gonadotropin-releasing hormone agonist, Gonadotropin-releasing hormone analogue, Gonadotropin-releasing hormone antagonist, Goserelin, Growth factor, Gynecomastia, Gynoid fat distribution, Hair disease, Hair follicle, Hepatotoxicity, Hidradenitis suppurativa, High-dose estrogen, Hirsutism, Homosexuality, Hormone receptor positive breast tumor, Hot flash, Human penis size, Hydroxyflutamide, Hyperandrogenism, Hyperkalemia, Hypersexuality, Hypoestrogenism, Hypothalamic–pituitary–gonadal axis, Immunogen, Infertility, Inocoterone acetate, Intersex, Irregular menstruation, Irreversible antagonist, Italy, Karyotype, Ketoconazole, Lean body mass, Leuprorelin, Levonorgestrel, Libido, Ligand (biochemistry), List of antiandrogens, List of estrogen esters, List of steroidal antiandrogens, Liver, Luteinizing hormone, Maximum androgen blockade, Medrogestone, Medroxyprogesterone acetate, Megestrol acetate, Membrane androgen receptor, Menopause, Metabolite, Metribolone, Mineralocorticoid, Muscle, Mutation, N-Terminal domain antiandrogen, N-terminus, Nandrolone, Negative feedback, Neurosteroid, Nilutamide, Nomegestrol acetate, Nonsteroidal, Nonsteroidal antiandrogen, Norethisterone, Nuclear receptor, Off-target activity, Oral contraceptive pill, Orchiectomy, Osaterone acetate, Osteoporosis, Ovandrotone albumin, Ovulation, Oxendolone, Paraphilia, Partial agonist, Pathophysiology, Pattern hair loss, Pedophilia, Penis, Peptide hormone, Phenotype, Physical strength, Pituitary gland, Polycystic ovary syndrome, Polyestradiol phosphate, Precocious puberty, Prednisone, Pregnancy, Pregnane, Pregnenolone, Preventive healthcare, Priapism, Progesterone, Progestin, Progestogen, Progonadotropin, Promegestone, Prostate, Prostate cancer, Protein–protein interaction, Puberty, Puberty blocker, Ralaniten, Ralaniten acetate, Receptor antagonist, Recidivism, Rosterolone, RU-22930, RU-58642, RU-58841, Saw palmetto extract, Seborrhoeic dermatitis, Secondary sex characteristic, Secretion, Selective androgen receptor degrader, Selective androgen receptor modulator, Selective estrogen receptor degrader, Serenoa, Seviteronel, Sex hormone-binding globulin, Sex offender, Sex organ, Sex reassignment surgery, Sex steroid, Sex-hormonal agent, Sexual differentiation, Sexual dysfunction, Side effect, Skin, Spironolactone, Steroid, Steroid hormone, Steroidal antiandrogen, Steroidogenesis inhibitor, Teratology, Testicle, Testosterone, Thalidomide, Tissue selectivity, Tolerability, Topical medication, Topilutamide, Topterone, Toxicity, Trans woman, Transcription (biology), Transgender hormone therapy (male-to-female), Transgender youth, Trimegestone, Trimethyltrienolone, United States Department of Health and Human Services, Vaccine, Vagina, Veterinary medicine, Virilization, Voice change, 5α-Reductase, 5α-Reductase inhibitor. Expand index (217 more) »
Abiraterone acetate
Abiraterone acetate, sold under the brand name Zytiga among others, is an antiandrogen medication which is used in the treatment of prostate cancer.
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Acne
Acne, also known as acne vulgaris, is a long-term skin disease that occurs when hair follicles are clogged with dead skin cells and oil from the skin.
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Adrenal gland
The adrenal glands (also known as suprarenal glands) are endocrine glands that produce a variety of hormones including adrenaline and the steroids aldosterone and cortisol.
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Adrenal insufficiency
Adrenal insufficiency is a condition in which the adrenal glands do not produce adequate amounts of steroid hormones, primarily cortisol; but may also include impaired production of aldosterone (a mineralocorticoid), which regulates sodium conservation, potassium secretion, and water retention.
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Alfatradiol
Alfatradiol, also known as 17α-estradiol and sold under the brand names Avicis, Avixis, Ell-Cranell Alpha, and Pantostin, is a weak estrogen and a 5α-reductase inhibitor which is used as a topical medication in the treatment of androgenic alopecia (pattern hair loss) in men and women.
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Allylestrenol
Allylestrenol, sold under the brand names Gestanin and Turinal among others, is a progestin medication which is used to treat recurrent and threatened miscarriage and to prevent premature labor in pregnant women.
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Alternative splicing
Alternative splicing, or differential splicing, is a regulated process during gene expression that results in a single gene coding for multiple proteins.
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Amenorrhea
Amenorrhoea is the absence of a menstrual period in a woman of reproductive age.
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Aminoglutethimide
Aminoglutethimide is an anti-steroid drug marketed under the tradename Cytadren by Novartis around the world.
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Anabolic steroid
Anabolic steroids, also known more properly as anabolic–androgenic steroids (AAS), are steroidal androgens that include natural androgens like testosterone as well as synthetic androgens that are structurally related and have similar effects to testosterone.
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Androgen
An androgen (from Greek andr-, the stem of the word meaning "man") is any natural or synthetic steroid hormone which regulates the development and maintenance of male characteristics in vertebrates by binding to androgen receptors.
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Androgen deprivation therapy
Androgen deprivation therapy (ADT), also called androgen suppression therapy, is an antihormone therapy whose main use is in treating prostate cancer.
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Androgen insensitivity syndrome
Androgen insensitivity syndrome (AIS) is an intersex condition in which there is a partial or complete inability of many cells in the affected genetic male to respond to androgenic hormones.
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Androgen receptor
The androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor that is activated by binding any of the androgenic hormones, including testosterone and dihydrotestosterone in the cytoplasm and then translocating into the nucleus.
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Androgen-dependent condition
An androgen-dependent condition, disease, disorder, or syndrome, is a medical condition that is, in part or full, dependent on, or is sensitive to, the presence of androgenic activity in the body.
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Androstenedione
Androstenedione, or 4-androstenedione (abbreviated as A4 or Δ4-dione), also known as androst-4-ene-3,17-dione, is an endogenous weak androgen steroid hormone and intermediate in the biosynthesis of estrone and of testosterone from dehydroepiandrosterone (DHEA).
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Androvax
Androvax, also known as androstenedione:human serum albumin conjugate, is an immunogen and vaccine against androstenedione that is used in veterinary medicine to increase the ovulation rate and number of lambs born to ewes.
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Anemia
Anemia is a decrease in the total amount of red blood cells (RBCs) or hemoglobin in the blood, or a lowered ability of the blood to carry oxygen.
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Antiandrogens in the environment
Antiandrogens in the environment have become a topic of concern.
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Antibiotic
An antibiotic (from ancient Greek αντιβιοτικά, antibiotiká), also called an antibacterial, is a type of antimicrobial drug used in the treatment and prevention of bacterial infections.
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Antibody
An antibody (Ab), also known as an immunoglobulin (Ig), is a large, Y-shaped protein produced mainly by plasma cells that is used by the immune system to neutralize pathogens such as pathogenic bacteria and viruses.
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Antiestrogen
Antiestrogens, also known as estrogen antagonists or estrogen blockers, are a class of drugs which prevent estrogens like estradiol from mediating their biological effects in the body.
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Antigonadotropin
An antigonadotropin is a drug which suppresses the activity and/or downstream effects of one or both of the gonadotropins, follicle-stimulating hormone (FSH) and luteinizing hormone (LH).
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Antimineralocorticoid
An antimineralocorticoid, MCRA, or an aldosterone antagonist, is a diuretic drug which antagonizes the action of aldosterone at mineralocorticoid receptors.
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Antiprogestogen
Antiprogestogens, or antiprogestins, also known as progesterone antagonists or progesterone blockers, are a class of drugs which prevent progestogens like progesterone from mediating their biological effects in the body.
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Apalutamide
Apalutamide, sold under the brand name Erleada, is a nonsteroidal antiandrogen (NSAA) medication which is used in the treatment of prostate cancer.
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Benign prostatic hyperplasia
Benign prostatic hyperplasia (BPH), also called prostate enlargement, is a noncancerous increase in size of the prostate.
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Benorterone
Benorterone, also known by its developmental code name SKF-7690 and as 17α-methyl-B-nortestosterone, is an steroidal antiandrogen which was studied for potential medical use but was never marketed.
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Benzoyl peroxide
Benzoyl peroxide (BPO) is a medication and industrial chemical.
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Bicalutamide
Bicalutamide, sold under the brand name Casodex among others, is an antiandrogen medication that is primarily used to treat prostate cancer.
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Bifluranol
Bifluranol (brand name Prostarex; former developmental code name BX-341) is a synthetic nonsteroidal estrogen of the stilbestrol group related to diethylstilbestrol that has been used as an antiandrogen in the United Kingdom in the treatment of benign prostatic hyperplasia.
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Bioassay
A bioassay is an analytical method to determine concentration or potency of a substance by its effect on living cells or tissues.
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Biological activity
In pharmacology, biological activity or pharmacological activity describes the beneficial or adverse effects of a drug on living matter.
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Biosynthesis
Biosynthesis (also called anabolism) is a multi-step, enzyme-catalyzed process where substrates are converted into more complex products in living organisms.
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Birth control
Birth control, also known as contraception and fertility control, is a method or device used to prevent pregnancy.
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Bisphenol A diglycidyl ether
Bisphenol A diglycidyl ether (commonly abbreviated BADGE or DGEBA) is an organic compound used as constituent of epoxy resins.
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Body fat percentage
The body fat percentage (BFP) of a human or other living being is the total mass of fat divided by total body mass, times 100; body fat includes essential body fat and storage body fat.
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Body hair
Body hair, or androgenic hair, is the terminal hair that develops on the human body during and after puberty.
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Body shape
Human body shape is a complex phenomenon with sophisticated detail and function.
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BOMT
BOMT, also known by its developmental code name Ro 7-2340 and as 6α-bromo-4-oxa-17α-methyl-5α-dihydrotestosterone, is a synthetic steroidal antiandrogen which was first developed in 1970 and was never marketed for medical use.
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Brain
The brain is an organ that serves as the center of the nervous system in all vertebrate and most invertebrate animals.
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Breast cancer
Breast cancer is cancer that develops from breast tissue.
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Breast development
Breast development, also known as mammogenesis, is a complex biological process in primates that takes place throughout a female's life.
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Breast enlargement
Breast enlargement is the enlargement of the breasts.
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Breast pain
Breast pain is a medical symptom that is most often associated with a developing disease or condition of the breast.
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Camille G. Wermuth
Camille Georges Wermuth (died September 2015) was a chemist in the Laboratoire de Pharmacochimie Moleculaire at the Universite Louis Pasteur in Illkirch, France.
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Castration
Castration (also known as gonadectomy) is any action, surgical, chemical, or otherwise, by which an individual loses use of the testicles.
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Cell division
Cell division is the process by which a parent cell divides into two or more daughter cells.
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Cell growth
The term cell growth is used in the contexts of biological cell development and cell division (reproduction).
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Cetrorelix
Cetrorelix, or cetrorelix acetate, sold under the brand name Cetrotide, is an injectable gonadotropin-releasing hormone (GnRH) antagonist.
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Chemical structure
A chemical structure determination includes a chemist's specifying the molecular geometry and, when feasible and necessary, the electronic structure of the target molecule or other solid.
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Chemotherapy
Chemotherapy (often abbreviated to chemo and sometimes CTX or CTx) is a type of cancer treatment that uses one or more anti-cancer drugs (chemotherapeutic agents) as part of a standardized chemotherapy regimen.
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Chlormadinone acetate
Chlormadinone acetate (CMA), sold under the brand names Belara, Lutéran, and Prostal among others, is a progestin and antiandrogen medication which is used in birth control pills to prevent pregnancy, as a component of menopausal hormone therapy, and in the treatment of gynecological disorders as well as androgen-dependent conditions like enlarged prostate and prostate cancer in men and acne and hirsutism in women.
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Cholesterol
Cholesterol (from the Ancient Greek chole- (bile) and stereos (solid), followed by the chemical suffix -ol for an alcohol) is an organic molecule.
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Cholesterol side-chain cleavage enzyme
Cholesterol side-chain cleavage enzyme is commonly referred to as P450scc, where "scc" is an acronym for side-chain cleavage.
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Cioteronel
Cioteronel (developmental code name CPC-10997; former tentative brand names Cyoctol, Ethocyn, X-Andron) is a nonsteroidal antiandrogen (NSAA) that was never marketed.
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Combined oral contraceptive pill
The combined oral contraceptive pill (COCP), often referred to as the birth control pill or colloquially as "the pill", is a type of birth control that is designed to be taken orally by women.
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Complete androgen insensitivity syndrome
Complete androgen insensitivity syndrome (CAIS) is a condition that results in the complete inability of the cell to respond to androgens.
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Congenital adrenal hyperplasia
Congenital adrenal hyperplasia (CAH) are any of several autosomal recessive diseases resulting from mutations of genes for enzymes mediating the biochemical steps of production of mineralocorticoids, glucocorticoids or sex steroids from cholesterol by the adrenal glands (steroidogenesis).
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Conjugated estrogens
Conjugated estrogens (CEs), or conjugated equine estrogens (CEEs), sold under the brand name Premarin (a contraction of "pregnant mares' urine") among others, is an estrogen medication which is used in menopausal hormone therapy and for various other indications.
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Cortexolone 17α-propionate
Cortexolone 17α-propionate (developmental code name CB-03-01; tentative brand names Breezula (for acne), Winlevi (for androgenic alopecia)), or 11-deoxycortisol 17α-propionate, is a synthetic steroidal antiandrogen – specifically, an androgen receptor antagonist – that is under development by Cassiopea and Intrepid Therapeutics for use as a topical medication in the treatment of androgen-dependent conditions including acne vulgaris and androgenic alopecia (male-pattern hair loss).
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Covalent bond
A covalent bond, also called a molecular bond, is a chemical bond that involves the sharing of electron pairs between atoms.
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Cutaneous condition
A cutaneous condition is any medical condition that affects the integumentary system—the organ system that encloses the body and includes skin, hair, nails, and related muscle and glands.
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CYP17A1 inhibitor
A CYP17A1 inhibitor is a type of drug which inhibits the enzyme CYP17A1.
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Cyproterone
Cyproterone, also known by its developmental code name SH-80881, is a steroidal antiandrogen which was studied in the 1960s and 1970s but was never introduced for medical use.
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Cyproterone acetate
Cyproterone acetate (CPA), sold alone under the brand name Androcur or with ethinylestradiol (EE) under the brand names Diane or Diane-35 among others, is an antiandrogen and progestogen which is used in the treatment of androgen-dependent conditions like acne, excessive hair growth, early puberty, and prostate cancer, as a component of feminizing hormone therapy for transgender women, and in birth control pills.
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Delmadinone acetate
Delmadinone acetate (DMA), sold under the brand name Tardak among others, is a progestin and antiandrogen which is used in veterinary medicine to treat androgen-dependent conditions such as benign prostatic hyperplasia.
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Depression (mood)
Depression is a state of low mood and aversion to activity that can affect a person's thoughts, behavior, tendencies, feelings, and sense of well-being.
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Dienogest
Dienogest, sold under the brand names Natazia and Qlaira among others, is a progestin medication which is used in birth control pills and in the treatment of endometriosis.
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Diethylstilbestrol
Diethylstilbestrol (DES), also known as stilbestrol or stilboestrol, is an estrogen medication which is mostly no longer used.
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Dihydrotestosterone
Dihydrotestosterone (DHT), or 5α-dihydrotestosterone (5α-DHT), also known as androstanolone or stanolone, is an endogenous androgen sex steroid and hormone.
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Dimethylcurcumin
Dimethylcurcumin (developmental code name ASC-J9) is a nonsteroidal antiandrogen and a synthetic curcuminoid which is under development by AndroScience Corporation as a topical medication for the treatment of acne vulgaris.
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DIMP (antiandrogen)
DIMP (developmental code name Ro 7-8117), or N-(3,5-dimethyl-4-isoxazolylmethyl)phthalimide, is a nonsteroidal antiandrogen (NSAA) structurally related to thalidomide (which also binds to and antagonizes the androgen receptor (AR)) that was first described in 1973 and was never marketed.
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Downregulation and upregulation
In the biological context of organisms' production of gene products, downregulation is the process by which a cell decreases the quantity of a cellular component, such as RNA or protein, in response to an external stimulus.
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Drospirenone
Drospirenone, sold under the brand names Yasmin and Angeliq among others, is a progestin medication which is used in birth control pills and in menopausal hormone therapy. The medication is available only in combination with an estrogen. It is taken by mouth. Drospirenone is a progestin, or a synthetic progestogen, and hence is an agonist of the progesterone receptor, the biological target of progestogens like progesterone. It has additional antimineralocorticoid and antiandrogenic activity and no other important hormonal activity. Drospirenone was introduced for medical use in 2000. It is available widely throughout the world. The medication is sometimes referred to as a "fourth-generation" progestin. It is available as a generic medication.https://www.drugs.com/availability/generic-yasmin.html.
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Drug
A drug is any substance (other than food that provides nutritional support) that, when inhaled, injected, smoked, consumed, absorbed via a patch on the skin, or dissolved under the tongue causes a temporary physiological (and often psychological) change in the body.
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Dutasteride
Dutasteride, sold under the brand name Avodart among others, is a medication used primarily to treat enlarged prostate in men.
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Efficacy
Efficacy is the ability to get a job done satisfactorily.
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Enzalutamide
Enzalutamide, sold under the brand name Xtandi, is a nonsteroidal antiandrogen (NSAA) medication which is used in the treatment of prostate cancer.
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Enzyme
Enzymes are macromolecular biological catalysts.
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Enzyme inhibitor
4QI9) An enzyme inhibitor is a molecule that binds to an enzyme and decreases its activity.
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EPI-001
EPI-001 is a novel experimental nonsteroidal antiandrogen (NSAA) that is under investigation for the treatment of prostate cancer.
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Epileptic seizure
An epileptic seizure is a brief episode of signs or symptoms due to abnormally excessive or synchronous neuronal activity in the brain.
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Epristeride
Epristeride, sold under the brand names Aipuliete and Chuanliu, is a medication which is used in the treatment of enlarged prostate in China.
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Erectile dysfunction
Erectile dysfunction (ED), also known as impotence, is a type of sexual dysfunction characterized by the inability to develop or maintain an erection of the penis during sexual activity.
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Erection
An erection (clinically: penile erection or penile tumescence) is a physiological phenomenon in which the penis becomes firm, engorged, and enlarged.
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Estradiol (medication)
Estradiol, also spelled oestradiol, is a medication and naturally occurring steroid hormone.
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Estradiol undecylate
Estradiol undecylate, or estradiol undecanoate, sold under the brand name Progynon Depot 100 among others, is a medication which has been used in the treatment of prostate cancer in men.
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Estradiol valerate
Estradiol valerate, sold under the brand names Progynova, Progynon Depot, and Delestrogen among others, is a medication which is used in hormone therapy such as for menopausal symptoms and in hormonal birth control.
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Estrogen
Estrogen, or oestrogen, is the primary female sex hormone.
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Estrogen (medication)
An estrogen is a type of medication which is used most commonly in hormonal birth control and menopausal hormone therapy.
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Ethinylestradiol
Ethinylestradiol (EE) is an estrogen medication which is used widely in birth control pills in combination with progestins.
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Fatigue
Fatigue is a subjective feeling of tiredness that has a gradual onset.
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Fecundity
In human demography and population biology, fecundity is the potential for reproduction of an organism or population, measured by the number of gametes (eggs), seed set, or asexual propagules.
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Female
Female (♀) is the sex of an organism, or a part of an organism, that produces non-mobile ova (egg cells).
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Femininity
Femininity (also called girlishness, womanliness or womanhood) is a set of attributes, behaviors, and roles generally associated with girls and women.
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Feminization (biology)
In biology and medicine, feminization is the development in an organism of physical characteristics that are usually unique to the female of the species.
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Fertility
Fertility is the natural capability to produce offspring.
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Fetus
A fetus is a stage in the prenatal development of viviparous organisms.
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Finasteride
Finasteride, sold under the brand names Proscar and Propecia among others, is a medication used mainly to treat an enlarged prostate or scalp hair loss in men.
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Flutamide
Flutamide, sold under the brand name Eulexin among others, is a nonsteroidal antiandrogen (NSAA) which is used primarily to treat prostate cancer.
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Follicle-stimulating hormone
Follicle-stimulating hormone (FSH) is a gonadotropin, a glycoprotein polypeptide hormone.
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Fulvestrant
Fulvestrant, sold under the brand name Faslodex among others, is a medication used to treat hormone receptor (HR)-positive metastatic breast cancer in postmenopausal women with disease progression as well as HR-positive, HER2-negative advanced breast cancer in combination with palbociclib in women with disease progression after endocrine therapy.
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Function (biology)
In biology, function has been defined in many ways.
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Gene expression
Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product.
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Gestonorone caproate
Gestonorone caproate, also known as gestronol hexanoate or norhydroxyprogesterone caproate and sold under the brand names Depostat and Primostat, is a progestin medication which is used in the treatment of enlarged prostate and endometrial cancer.
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Glucocorticoid
Glucocorticoids are a class of corticosteroids, which are a class of steroid hormones.
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Gonad
A gonad or sex gland or reproductive gland is a mixed gland that produces the gametes (sex cells) and sex hormones of an organism.
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Gonadotropin
Gonadotropins are glycoprotein polypeptide hormones secreted by gonadotrope cells of the anterior pituitary of vertebrates.
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Gonadotropin-releasing hormone
Gonadotropin-releasing hormone (GnRH) also known as gonadoliberin, and by various other names in its endogenous form and as gonadorelin in its pharmaceutical form, is a releasing hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary.
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Gonadotropin-releasing hormone agonist
A gonadotropin-releasing hormone agonist (GnRH agonist) is a type of medication which affects gonadotropins and sex hormones.
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Gonadotropin-releasing hormone analogue
A gonadotropin-releasing hormone analogue (GnRH analogue or analog), also known as a luteinizing hormone releasing hormone agonist (LHRH agonist) or LHRH analogue is a synthetic peptide drug modeled after the human hypothalamic gonadotropin-releasing hormone (GnRH).
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Gonadotropin-releasing hormone antagonist
Gonadotropin-releasing hormone antagonists (GnRH antagonists) are a class of medications that antagonize the gonadotropin-releasing hormone receptor (GnRH receptor) and thus the action of gonadotropin-releasing hormone (GnRH).
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Goserelin
Goserelin, or goserelin acetate, sold under the brand name Zoladex (by AstraZeneca) among others, is a medication which is used to suppress production of the sex hormones (testosterone and estrogen), particularly in the treatment of breast and prostate cancer.
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Growth factor
A growth factor is a naturally occurring substance capable of stimulating cellular growth, proliferation, healing, and cellular differentiation.
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Gynecomastia
Gynecomastia is an endocrine system disorder in which a noncancerous increase in the size of male breast tissue occurs.
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Gynoid fat distribution
Gynoid fat refers to the body fat that forms around the hips, breasts and thighs.
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Hair disease
Hair diseases are disorders primarily associated with the follicles of the hair.
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Hair follicle
The hair follicle is a dynamic organ found in mammalian skin.
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Hepatotoxicity
Hepatotoxicity (from hepatic toxicity) implies chemical-driven liver damage.
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Hidradenitis suppurativa
Hidradenitis suppurativa (HS), also known as acne inversa, is a long term skin disease characterized by the occurrence of inflamed and swollen lumps.
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High-dose estrogen
High-dose estrogen (HDE) is a type of hormone therapy in which high doses of estrogens are given.
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Hirsutism
Hirsutism is excessive body hair in men and women on parts of the body where hair is normally absent or minimal, such as on the chin or chest in particular, or the face or body in general.
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Homosexuality
Homosexuality is romantic attraction, sexual attraction or sexual behavior between members of the same sex or gender.
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Hormone receptor positive breast tumor
A hormone-receptor-positive tumor is a tumor which consists of cells that express receptors for certain hormones.
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Hot flash
Hot flashes (American English) or hot flushes (British English) are a form of flushing due to reduced levels of estradiol.
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Human penis size
The most accurate measurement of the size of a human penis can be derived from several readings at different times since there is natural minor variability in size depending upon arousal level, time of day, room temperature, frequency of sexual activity, and reliability of measurement.
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Hydroxyflutamide
Hydroxyflutamide (HF, OHF) (developmental code name SCH-16423), or 2-hydroxyflutamide, is a nonsteroidal antiandrogen (NSAA) and the major active metabolite of flutamide, which is considered to be a a prodrug of hydroxyflutamide as the active form.
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Hyperandrogenism
Hyperandrogenism, also known as androgen excess, is a medical condition characterized by excessive levels of androgens (male sex hormones such as testosterone) in the female body and the associated effects of the elevated androgen levels.
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Hyperkalemia
Hyperkalemia, also spelled hyperkalaemia, is an elevated level of potassium (K+) in the blood serum.
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Hypersexuality
Hypersexuality is a clinical diagnosis used by mental healthcare professionals to describe extremely frequent or suddenly increased libido.
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Hypoestrogenism
Hypoestrogenism, or estrogen deficiency, refers to a lower than normal level of estrogen, the primary sex hormone in women.
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Hypothalamic–pituitary–gonadal axis
The hypothalamic–pituitary–gonadal axis (HPG axis) refers to the hypothalamus, pituitary gland, and gonadal glands as if these individual endocrine glands were a single entity.
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Immunogen
An immunogen is an antigen or any substance that may be specifically bound by components of the immune system (antibody, lymphocytes).
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Infertility
Infertility is the inability of a person, animal or plant to reproduce by natural means.
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Inocoterone acetate
Inocoterone acetate (developmental code names RU-38882, RU-882) is a steroid-like nonsteroidal antiandrogen (NSAA) that was developed for topical administration to treat acne but was never marketed.
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Intersex
Intersex people are born with any of several variations in sex characteristics including chromosomes, gonads, sex hormones, or genitals that, according to the UN Office of the High Commissioner for Human Rights, "do not fit the typical definitions for male or female bodies".
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Irregular menstruation
Irregular menstruation is a menstrual disorder whose manifestations include irregular cycle lengths as well as metrorrhagia (vaginal bleeding between expected periods).
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Irreversible antagonist
An irreversible antagonist is a type of antagonist that binds permanently to a receptor, either by forming a covalent bond to the active site, or alternatively just by binding so tightly that the rate of dissociation is effectively zero at relevant time scales.
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Italy
Italy (Italia), officially the Italian Republic (Repubblica Italiana), is a sovereign state in Europe.
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Karyotype
A karyotype is the number and appearance of chromosomes in the nucleus of a eukaryotic cell.
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Ketoconazole
Ketoconazole is a synthetic imidazole antifungal drug used primarily to treat fungal infections.
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Lean body mass
Lean body mass is a component of body composition, calculated by subtracting body fat weight from total body weight: total body weight is lean plus fat.
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Leuprorelin
Leuprorelin, also known as leuprolide, is a manufactured version of a hormone used to treat prostate cancer, breast cancer, endometriosis, uterine fibroids, and early puberty.
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Levonorgestrel
Levonorgestrel is a hormonal medication which is used in a number of birth control methods.
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Libido
Libido, colloquially known as sex drive, is a person's overall sexual drive or desire for sexual activity.
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Ligand (biochemistry)
In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose.
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List of antiandrogens
This is a list of antiandrogens, or drugs that prevent the effects of androgens like testosterone and dihydrotestosterone (DHT).
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List of estrogen esters
This is a list of estrogen esters, or ester prodrugs of estrogens.
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List of steroidal antiandrogens
This is a list of steroidal antiandrogens.
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Liver
The liver, an organ only found in vertebrates, detoxifies various metabolites, synthesizes proteins, and produces biochemicals necessary for digestion.
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Luteinizing hormone
Luteinizing hormone (LH, also known as lutropin and sometimes lutrophin) is a hormone produced by gonadotropic cells in the anterior pituitary gland.
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Maximum androgen blockade
Maximum or maximal androgen blockade (MAB) or complete or combined androgen blockade (CAB) is a medical treatment involving the combination of both androgen receptor (AR) antagonism and inhibition or suppression of androgen production to attain maximal effectiveness in androgen deprivation therapy (ADT).
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Medrogestone
Medrogestone, sold under the brand name Colprone among others, is a progestin medication which has been used in menopausal hormone therapy and in the treatment of gynecological disorders.
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Medroxyprogesterone acetate
Medroxyprogesterone acetate (MPA), sold under the brand name Depo-Provera among others, is a hormonal medication of the progestin type.
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Megestrol acetate
Megestrol acetate (MGA), sold under the brand name Megace among others, is a progestin medication which is used mainly as an appetite stimulant to treat wasting syndromes such as cachexia.
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Membrane androgen receptor
Membrane androgen receptors (mARs) are a group of G protein-coupled receptors (GPCRs) which bind and are activated by testosterone and/or other androgens.
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Menopause
Menopause, also known as the climacteric, is the time in most women's lives when menstrual periods stop permanently, and they are no longer able to bear children.
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Metabolite
A metabolite is the intermediate end product of metabolism.
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Metribolone
Metribolone (developmental code name R1881), also known as methyltrienolone, is a synthetic and orally active anabolic–androgenic steroid (AAS) and a 17α-alkylated nandrolone (19-nortestosterone) derivative which was never marketed for medical use but has been widely used in scientific research as a hot ligand in androgen receptor (AR) ligand binding assays (LBAs) and as a photoaffinity label for the AR.
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Mineralocorticoid
Mineralocorticoids are a class of corticosteroids, which in turn are a class of steroid hormones.
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Muscle
Muscle is a soft tissue found in most animals.
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Mutation
In biology, a mutation is the permanent alteration of the nucleotide sequence of the genome of an organism, virus, or extrachromosomal DNA or other genetic elements.
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N-Terminal domain antiandrogen
N-Terminal domain antiandrogens are a novel type of antiandrogen that bind to the ''N''-terminal domain of the androgen receptor (AR) instead of the ligand-binding domain (where all currently-available antiandrogens bind) and disrupt interactions between the AR and its coregulatory binding partners, thereby blocking AR-mediated gene transcription.
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N-terminus
The N-terminus (also known as the amino-terminus, NH2-terminus, N-terminal end or amine-terminus) is the start of a protein or polypeptide referring to the free amine group (-NH2) located at the end of a polypeptide.
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Nandrolone
Nandrolone, also known as 19-nortestosterone, is an androgen and anabolic steroid (AAS) which is used in the form of esters such as nandrolone decanoate (brand name Deca-Durabolin) and nandrolone phenylpropionate (brand name Durabolin).
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Negative feedback
Negative feedback (or balancing feedback) occurs when some function of the output of a system, process, or mechanism is fed back in a manner that tends to reduce the fluctuations in the output, whether caused by changes in the input or by other disturbances.
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Neurosteroid
Neurosteroids, also known as neuroactive steroids, are endogenous or exogenous steroids that rapidly alter neuronal excitability through interaction with ligand-gated ion channels and other cell surface receptors.
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Nilutamide
Nilutamide, sold under the brand names Nilandron and Anandron, is a nonsteroidal antiandrogen (NSAA) which is used in the treatment of prostate cancer.
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Nomegestrol acetate
Nomegestrol acetate (NOMAC), sold under the brand names Lutenyl and Zoely among others, is a progestin medication which is used in birth control pills, menopausal hormone therapy, and for the treatment of gynecological disorders.
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Nonsteroidal
Nonsteroidal is a term which is used to describe a compound that is not a steroid.
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Nonsteroidal antiandrogen
A nonsteroidal antiandrogen (NSAA) is an antiandrogen with a nonsteroidal chemical structure.
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Norethisterone
Norethisterone, also known as norethindrone and sold under the brand names Aygestin and Primolut N among many others, is a progestin medication which is used in birth control pills, menopausal hormone therapy, and for the treatment of gynecological disorders.
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Nuclear receptor
In the field of molecular biology, nuclear receptors are a class of proteins found within cells that are responsible for sensing steroid and thyroid hormones and certain other molecules.
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Off-target activity
Off-target activity is biological activity of a drug that is different from and not at that of its intended biological target.
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Oral contraceptive pill
Oral contraceptives, abbreviated OCPs, also known as birth control pills, are medications taken by mouth for the purpose of birth control.
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Orchiectomy
Orchiectomy (also named orchidectomy, and sometimes shortened as orchi) is a surgical procedure in which one or both testicles are removed.
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Osaterone acetate
Osaterone acetate, sold under the brand name Ypozane, is a medication which is used in veterinary medicine in Europe in the treatment of enlarged prostate in dogs.
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Osteoporosis
Osteoporosis is a disease where increased bone weakness increases the risk of a broken bone.
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Ovandrotone albumin
Ovandrotone albumin (brand names Fecundin, Ovastim), also known as polyandroalbumin, as well as ovandrotone:human serum albumin conjugate, is an immunogen and vaccine against androstenedione that is used in veterinary medicine to increase the ovulation rate and number of lambs born to ewes.
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Ovulation
Ovulation is the release of eggs from the ovaries.
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Oxendolone
Oxendolone, sold under the brand names Prostetin and Roxenone, is an antiandrogen and progestin medication which is used in Japan in the treatment of enlarged prostate.
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Paraphilia
Paraphilia (previously known as sexual perversion and sexual deviation) is the experience of intense sexual arousal to atypical objects, situations, fantasies, behaviors, or individuals.
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Partial agonist
In pharmacology, partial agonists are drugs that bind to and activate a given receptor, but have only partial efficacy at the receptor relative to a full agonist.
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Pathophysiology
Pathophysiology or physiopathology is a convergence of pathology with physiology.
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Pattern hair loss
Pattern hair loss, known as male-pattern hair loss (MPHL) when it affects males and female-pattern hair loss (FPHL) when it affects females, is hair loss that primarily affects the top and front of the scalp.
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Pedophilia
Pedophilia, or paedophilia, is a psychiatric disorder in which an adult or older adolescent experiences a primary or exclusive sexual attraction to prepubescent children.
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Penis
A penis (plural penises or penes) is the primary sexual organ that male animals use to inseminate sexually receptive mates (usually females and hermaphrodites) during copulation.
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Peptide hormone
Peptide hormones or protein hormones are hormones whose molecules are peptides or proteins, respectively.
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Phenotype
A phenotype is the composite of an organism's observable characteristics or traits, such as its morphology, development, biochemical or physiological properties, behavior, and products of behavior (such as a bird's nest).
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Physical strength
Physical strength is the measure of an animal's exertion of force on physical objects.
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Pituitary gland
An explanation of the development of the pituitary gland (Hypophysis cerebri) & the congenital anomalies. In vertebrate anatomy, the pituitary gland, or hypophysis, is an endocrine gland about the size of a pea and weighing in humans.
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Polycystic ovary syndrome
Polycystic ovary syndrome (PCOS) is a set of symptoms due to elevated androgens (male hormones) in females.
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Polyestradiol phosphate
Polyestradiol phosphate (PEP), sold under the brand name Estradurin, is a medication which is used primarily in the treatment of prostate cancer in men.
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Precocious puberty
In medicine, precocious puberty is puberty occurring at an unusually early age.
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Prednisone
Prednisone is a synthetic glucocorticoid drug that is mostly used to suppress the immune system.
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Pregnancy
Pregnancy, also known as gestation, is the time during which one or more offspring develops inside a woman.
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Pregnane
Pregnane is a C21 steroid and, indirectly, a parent of progesterone.
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Pregnenolone
Pregnenolone (P5), or pregn-5-en-3β-ol-20-one, is an endogenous steroid and precursor/metabolic intermediate in the biosynthesis of most of the steroid hormones, including the progestogens, androgens, estrogens, glucocorticoids, and mineralocorticoids.
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Preventive healthcare
Preventive healthcare (alternately preventive medicine, preventative healthcare/medicine, or prophylaxis) consists of measures taken for disease prevention, as opposed to disease treatment.
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Priapism
Priapism is a condition in which a penis remains erect for hours in the absence of stimulation or after stimulation has ended.
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Progesterone
Progesterone (P4) is an endogenous steroid and progestogen sex hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species.
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Progestin
A progestin is a type of medication which is used most commonly in hormonal birth control and menopausal hormone therapy.
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Progestogen
Progestogens, also sometimes spelled progestagens or gestagens, are a class of steroid hormones that bind to and activate the progesterone receptor (PR).
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Progonadotropin
A progonadotropin, or hypergonadotropin, also known as a gonad stimulant, is a type of drug which increases the secretion of one or both of the major gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH).
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Promegestone
Promegestone, sold under the brand name Surgestone, is a progestin medication which is used in menopausal hormone therapy and in the treatment of gynecological disorders.
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Prostate
The prostate (from Ancient Greek προστάτης, prostates, literally "one who stands before", "protector", "guardian") is a compound tubuloalveolar exocrine gland of the male reproductive system in most mammals.
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Prostate cancer
Prostate cancer is the development of cancer in the prostate, a gland in the male reproductive system.
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Protein–protein interaction
Protein–protein interactions (PPIs) are the physical contacts of high specificity established between two or more protein molecules as a result of biochemical events steered by electrostatic forces including the hydrophobic effect.
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Puberty
Puberty is the process of physical changes through which a child's body matures into an adult body capable of sexual reproduction.
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Puberty blocker
Puberty blockers, also called puberty inhibitors, puberty suppressors, or hormone suppressors, are a group of medications used to inhibit puberty.
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Ralaniten
Ralaniten (developmental code name EPI-002) is an N-terminal domain antiandrogen which was never marketed.
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Ralaniten acetate
Ralaniten acetate (developmental code name EPI-506) is an experimental nonsteroidal antiandrogen (NSAA) which was developed by ESSA Pharmaceuticals and was under investigation for the treatment of prostate cancer.
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Receptor antagonist
A receptor antagonist is a type of receptor ligand or drug that blocks or dampens a biological response by binding to and blocking a receptor rather than activating it like an agonist.
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Recidivism
Recidivism (from recidive and ism, from Latin recidīvus "recurring", from re- "back" and cadō "I fall") is the act of a person repeating an undesirable behavior after they have either experienced negative consequences of that behavior, or have been trained to extinguish that behavior.
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Rosterolone
Rosterolone (developmental code name SH-434), also known as 17α-propylmesterolone or 1α-methyl-17α-propyl-5α-androstan-17β-ol-3-one, is a steroidal antiandrogen which was first described in 1984 and was developed for topical administration but was never marketed.
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RU-22930
RU-22930 is a nonsteroidal antiandrogen (NSAA) related to the NSAAs flutamide and nilutamide (RU-23908) and was developed by Roussel Uclaf but was never marketed.
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RU-58642
RU-58642 is a nonsteroidal antiandrogen (NSAA) derived from nilutamide with very high affinity and selectivity for the androgen receptor (AR), which made it among the most potent and efficacious antiandrogens known at the time of its discovery.
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RU-58841
RU-58841, also known as PSK-3841 or HMR-3841, is a nonsteroidal antiandrogen (NSAA) which was formerly under investigation by ProStrakan (previously ProSkelia and Strakan) for potential use as a topical treatment for androgen-dependent conditions including acne, pattern hair loss, and excessive hair growth.
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Saw palmetto extract
Saw palmetto extract is an extract of the fruit of the saw palmetto.
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Seborrhoeic dermatitis
Seborrhoeic dermatitis, also known as seborrhoea, is a long-term skin disorder.
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Secondary sex characteristic
Secondary sex characteristics are features that appear during puberty in humans, and at sexual maturity in other animals.
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Secretion
Secretion is the movement of material from one point to another, e.g. secreted chemical substance from a cell or gland.
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Selective androgen receptor degrader
A selective androgen receptor degrader or downregulator (SARD) is a type of drug which interacts with the androgen receptor (AR) such that it causes the AR to be degraded and thus downregulated.
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Selective androgen receptor modulator
Selective androgen receptor modulators or SARMs are a novel class of androgen receptor ligands.
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Selective estrogen receptor degrader
A selective estrogen receptor degrader or downregulator (SERD) is a type of drug which binds to the estrogen receptor (ER) and, in the process of doing so, causes the ER to be degraded and thus downregulated.
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Serenoa
Serenoa repens, commonly known as saw palmetto, is the sole species currently classified in the genus Serenoa.
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Seviteronel
Seviteronel (developmental codes VT-464 and, formerly, INO-464) is an experimental cancer medication which is under development by Viamet Pharmaceuticals and Innocrin Pharmaceuticals for the treatment of prostate cancer and breast cancer.
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Sex hormone-binding globulin
Sex hormone-binding globulin (SHBG) or sex steroid-binding globulin (SSBG) is a glycoprotein that binds to the two sex hormones: androgen and estrogen.
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Sex offender
A sex offender (sexual offender, sex abuser, or sexual abuser) is a person who has committed a sex crime.
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Sex organ
A sex organ (or reproductive organ) is any part of an animal's body that is involved in sexual reproduction.
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Sex reassignment surgery
Sex reassignment surgery or SRS (also known as gender reassignment surgery, gender confirmation surgery, genital reconstruction surgery, gender-affirming surgery, or sex realignment surgery) is the surgical procedure (or procedures) by which a transgender person's physical appearance and function of their existing sexual characteristics are altered to resemble that socially associated with their identified gender.
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Sex steroid
Sex steroids, also known as gonadocorticoids and gonadal steroids, are steroid hormones that interact with vertebrate androgen or estrogen receptors.
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Sex-hormonal agent
A sex-hormonal agent, also known as a sex-hormone receptor modulator, is a type of hormonal agent which specifically modulates the effects of sex hormones and of their biological targets, the sex hormone receptors.
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Sexual differentiation
Sexual differentiation is the process of development of the differences between males and females from an undifferentiated zygote.
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Sexual dysfunction
Sexual dysfunction (or sexual malfunction or sexual disorder) is difficulty experienced by an individual or a couple during any stage of a normal sexual activity, including physical pleasure, desire, preference, arousal or orgasm.
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Side effect
In medicine, a side effect is an effect, whether therapeutic or adverse, that is secondary to the one intended; although the term is predominantly employed to describe adverse effects, it can also apply to beneficial, but unintended, consequences of the use of a drug.
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Skin
Skin is the soft outer tissue covering vertebrates.
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Spironolactone
Spironolactone, sold under the brand name Aldactone among others, is a medication that is primarily used to treat fluid build-up due to heart failure, liver scarring, or kidney disease.
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Steroid
A steroid is a biologically active organic compound with four rings arranged in a specific molecular configuration.
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Steroid hormone
A steroid hormone is a steroid that acts as a hormone.
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Steroidal antiandrogen
A steroidal antiandrogen (SAA) is an antiandrogen with a steroidal chemical structure.
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Steroidogenesis inhibitor
A steroidogenesis inhibitor, also known as a steroid biosynthesis inhibitor, is a type of drug which inhibits one or more of the enzymes that are involved in the process of steroidogenesis, the biosynthesis of endogenous steroids and steroid hormones.
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Teratology
Teratology is the study of abnormalities of physiological development.
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Testicle
The testicle or testis is the male reproductive gland in all animals, including humans.
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Testosterone
Testosterone is the primary male sex hormone and an anabolic steroid.
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Thalidomide
Thalidomide, sold under the brand name Immunoprin, among others, is an immunomodulatory drug and the prototype of the thalidomide class of drugs.
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Tissue selectivity
Tissue selectivity is a topic in distribution (pharmacology) and a property of some drugs.
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Tolerability
Tolerability refers to the degree to which overt adverse effects of a drug can be tolerated by a patient.
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Topical medication
A topical medication is a medication that is applied to a particular place on or in the body.
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Topilutamide
Topilutamide, known more commonly as fluridil and sold under the brand name Eucapil, is a topical nonsteroidal antiandrogen (NSAA) related to flutamide and bicalutamide which is marketed by Interpharma Praha and used in certain European countries for the treatment of androgenic alopecia (pattern hair loss or baldness).
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Topterone
Topterone (developmental code name WIN-17665), also known as 17α-propyltestosterone (or simply propyltestosterone) or as 17α-propylandrost-4-en-17β-ol-3-one, is a steroidal antiandrogen that was first reported in 1978 and was developed for topical administration but, due to poor effectiveness, was never marketed.
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Toxicity
Toxicity is the degree to which a chemical substance or a particular mixture of substances can damage an organism.
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Trans woman
A trans woman (sometimes trans-woman or transwoman) is a woman who was assigned male at birth.
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Transcription (biology)
Transcription is the first step of gene expression, in which a particular segment of DNA is copied into RNA (especially mRNA) by the enzyme RNA polymerase.
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Transgender hormone therapy (male-to-female)
Transgender hormone therapy of the male-to-female (MTF) type, also known as feminizing hormone therapy, is a form of hormone replacement therapy (HRT) and sex reassignment therapy which is used to change the secondary sexual characteristics of transgender people from masculine (or androgynous) to feminine.
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Transgender youth
Transgender youth are children and adolescents who are transgender and/or transsexual.
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Trimegestone
Trimegestone, sold under the brand names Ondeva and Totelle among others, is a progestin medication which is used in menopausal hormone therapy and in the prevention of postmenopausal osteoporosis.
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Trimethyltrienolone
Trimethyltrienolone (TMT), also known by its developmental code name R-2956 or RU-2956, is an antiandrogen medication which was never introduced for medical use but has been used in scientific research.
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United States Department of Health and Human Services
The United States Department of Health and Human Services (HHS), also known as the Health Department, is a cabinet-level department of the U.S. federal government with the goal of protecting the health of all Americans and providing essential human services.
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Vaccine
A vaccine is a biological preparation that provides active acquired immunity to a particular disease.
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Vagina
In mammals, the vagina is the elastic, muscular part of the female genital tract.
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Veterinary medicine
Veterinary medicine is the branch of medicine that deals with the prevention, diagnosis and treatment of disease, disorder and injury in non-human animals.
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Virilization
Virilization or masculinization is the biological development of sex differences, changes that make a male body different from a female body.
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Voice change
A voice change or voice mutation, sometimes referred to as a voice break, commonly refers to the deepening of the voice of people as they reach puberty.
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5α-Reductase
5α-reductases, also known as 3-oxo-5α-steroid 4-dehydrogenases, are enzymes involved in steroid metabolism.
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5α-Reductase inhibitor
5α-Reductase inhibitors (5-ARIs), also known as dihydrotestosterone (DHT) blockers, are a class of medications with antiandrogenic effects which are used primarily in the treatment of enlarged prostate and scalp hair loss.
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Redirects here:
AR antagonist, AR antagonists, AR blocker, AR blockers, Androgen antagonist, Androgen antagonists, Androgen biosynthesis inhibitor, Androgen biosynthesis inhibitors, Androgen blocker, Androgen blockers, Androgen production inhibitor, Androgen production inhibitors, Androgen receptor antagonist, Androgen receptor antagonists, Androgen receptor blocker, Androgen receptor blockers, Androgen steroidogenesis inhibitor, Androgen steroidogenesis inhibitors, Androgen synthesis inhibitor, Androgen synthesis inhibitors, Anti-androgen, Anti-androgenic, Anti-androgens, Antiandrogen therapy, Antiandrogenic, Antiandrogens, Antigonadotropic anti-androgen, Antigonadotropic anti-androgens, Antigonadotropic antiandrogen, Antigonadotropic antiandrogens, Pure anti-androgen, Pure anti-androgens, Pure antiandrogen, Pure antiandrogens, Testosterone antagonist, Testosterone antagonists, Testosterone biosynthesis inhibitor, Testosterone biosynthesis inhibitors, Testosterone blocker, Testosterone blockers, Testosterone synthesis inhibitor, Testosterone synthesis inhibitors.
References
[1] https://en.wikipedia.org/wiki/Antiandrogen
