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Table of Contents

1. 305 relations: Acetylcholine receptor, Acta Psychiatrica Scandinavica, Active placebo, Addiction, Adverse effect, Advertising, Agomelatine, Agoraphobia, Akathisia, Alcohol dependence, Alpha-1 adrenergic receptor, American Psychiatric Association, Amineptine, Amitriptyline, Amotivational syndrome, Amphetamine, Amphetamine type stimulant, Anorexia nervosa, Anorgasmia, Anticonvulsant, Antidepressant, Antidepressant discontinuation syndrome, Antidepressants in Japan, Antihistamine, Antipsychotic, Anxiety, Anxiety disorder, Anxiolytic, Apathy, Aripiprazole, Arrhythmia, Attention deficit hyperactivity disorder, Atypical antidepressant, Atypical antipsychotic, Atypical depression, Augmentation (pharmacology), Avoidant personality disorder, Ayahuasca, Binge eating disorder, Biology of depression, Bipolar disorder, Blinded experiment, Body dysmorphic disorder, Borderline personality disorder, British Journal of Pharmacology, Bryan Molloy, Bulimia nervosa, Bupropion, Cardiac arrest, Cardiovascular disease, ... Expand index (255 more) » « Shrink index

2. Anaphrodisia
3. Drug classes defined by psychological effects
4. Major depressive disorder

Acetylcholine receptor

An acetylcholine receptor (abbreviated AChR) or a cholinergic receptor is an integral membrane protein that responds to the binding of acetylcholine, a neurotransmitter.

See Antidepressant and Acetylcholine receptor

Acta Psychiatrica Scandinavica

The Acta Psychiatrica Scandinavica is a Scandinavian peer-reviewed medical journal containing original research, systematic reviews etc.

See Antidepressant and Acta Psychiatrica Scandinavica

Active placebo

An active placebo is a placebo that produces noticeable side effects that may convince the person being treated that they are receiving a legitimate treatment, rather than an inert placebo.

See Antidepressant and Active placebo

Addiction

Addiction is a neuropsychological disorder characterized by a persistent and intense urge to use a drug or engage in a behavior that produces natural reward, despite substantial harm and other negative consequences.

See Antidepressant and Addiction

Adverse effect

An adverse effect is an undesired harmful effect resulting from a medication or other intervention, such as surgery.

See Antidepressant and Adverse effect

Advertising

Advertising is the practice and techniques employed to bring attention to a product or service.

See Antidepressant and Advertising

Agomelatine

Agomelatine, sold under the brand names Valdoxan and Thymanax, among others, is an atypical antidepressant most commonly used to treat major depressive disorder and generalized anxiety disorder. Antidepressant and Agomelatine are antidepressants.

See Antidepressant and Agomelatine

Agoraphobia

Agoraphobia is a mental and behavioral disorder, specifically an anxiety disorder characterized by symptoms of anxiety in situations where the person perceives their environment to be unsafe with no easy way to escape.

See Antidepressant and Agoraphobia

Akathisia

Akathisia (IPA: /æ.kə.ˈθɪ.si.ə/) is a movement disorder characterized by a subjective feeling of inner restlessness accompanied by mental distress and an inability to sit still.

See Antidepressant and Akathisia

Alcohol dependence

Alcohol dependence is a previous (DSM-IV and ICD-10) psychiatric diagnosis in which an individual is physically or psychologically dependent upon alcohol (also chemically known as ethanol).

See Antidepressant and Alcohol dependence

Alpha-1 adrenergic receptor

alpha-1 (α1) adrenergic receptors are G protein-coupled receptors (GPCRs) associated with the Gq heterotrimeric G protein.

See Antidepressant and Alpha-1 adrenergic receptor

American Psychiatric Association

The American Psychiatric Association (APA) is the main professional organization of psychiatrists and trainee psychiatrists in the United States, and the largest psychiatric organization in the world.

See Antidepressant and American Psychiatric Association

Amineptine

Amineptine, formerly sold under the brand name Survector among others, is an atypical antidepressant of the tricyclic antidepressant (TCA) family.

See Antidepressant and Amineptine

Amitriptyline

Amitriptyline, sold under the brand name Elavil among others, is a tricyclic antidepressant primarily used to treat major depressive disorder, and a variety of pain syndromes such as neuropathic pain, fibromyalgia, migraine and tension headaches.

See Antidepressant and Amitriptyline

Amotivational syndrome

Amotivational syndrome is a chronic psychiatric disorder characterized by signs that are linked to cognitive and emotional states such as detachment, blunted emotion and drives, executive functions like memory and attention, disinterest, passivity, apathy, and a general lack of motivation.

See Antidepressant and Amotivational syndrome

Amphetamine

Amphetamine (contracted from alpha-methylphenethylamine) is a central nervous system (CNS) stimulant that is used in the treatment of attention deficit hyperactivity disorder (ADHD), narcolepsy, and obesity.

See Antidepressant and Amphetamine

Amphetamine type stimulant

Amphetamine type stimulants (ATS) are a group of synthetic drugs that are chemical derivatives of the parent compound alpha-methylphenethylamine, also known as amphetamine.

See Antidepressant and Amphetamine type stimulant

Anorexia nervosa

Anorexia nervosa (AN), often referred to simply as anorexia, is an eating disorder characterized by food restriction, body image disturbance, fear of gaining weight, and an overpowering desire to be thin.

See Antidepressant and Anorexia nervosa

Anorgasmia

Anorgasmia is a type of sexual dysfunction in which a person cannot achieve orgasm despite adequate sexual stimulation.

See Antidepressant and Anorgasmia

Anticonvulsant

Anticonvulsants (also known as antiepileptic drugs, antiseizure drugs, or anti-seizure medications (ASM)) are a diverse group of pharmacological agents used in the treatment of epileptic seizures.

See Antidepressant and Anticonvulsant

Antidepressant

Antidepressants are a class of medications used to treat major depressive disorder, anxiety disorders, chronic pain, and addiction. Antidepressant and Antidepressant are Anaphrodisia, antidepressants, drug classes defined by psychological effects and major depressive disorder.

See Antidepressant and Antidepressant

Antidepressant discontinuation syndrome

Antidepressant discontinuation syndrome, also called antidepressant withdrawal syndrome, is a condition that can occur following the interruption, reduction, or discontinuation of antidepressant medication following its continuous use of at least a month. Antidepressant and antidepressant discontinuation syndrome are antidepressants.

See Antidepressant and Antidepressant discontinuation syndrome

Antidepressants in Japan

The number of new psychiatric drugs, and especially antidepressants on the market in Japan, is significantly less than Western countries. Antidepressant and antidepressants in Japan are antidepressants.

See Antidepressant and Antidepressants in Japan

Antihistamine

Antihistamines are drugs which treat allergic rhinitis, common cold, influenza, and other allergies.

See Antidepressant and Antihistamine

Antipsychotic

Antipsychotics, previously known as neuroleptics and major tranquilizers, are a class of psychotropic medication primarily used to manage psychosis (including delusions, hallucinations, paranoia or disordered thought), principally in schizophrenia but also in a range of other psychotic disorders. Antidepressant and Antipsychotic are drug classes defined by psychological effects.

See Antidepressant and Antipsychotic

Anxiety

Anxiety is an emotion which is characterised by an unpleasant state of inner turmoil and includes feelings of dread over anticipated events.

See Antidepressant and Anxiety

Anxiety disorder

Anxiety disorders are a group of mental disorders characterized by significant and uncontrollable feelings of anxiety and fear such that a person's social, occupational, and personal functions are significantly impaired.

See Antidepressant and Anxiety disorder

Anxiolytic

An anxiolytic (also antipanic or anti-anxiety agent) is a medication or other intervention that reduces anxiety. Antidepressant and anxiolytic are drug classes defined by psychological effects.

See Antidepressant and Anxiolytic

Apathy

Apathy, also referred to as indifference, is a lack of feeling, emotion, interest, or concern about something.

See Antidepressant and Apathy

Aripiprazole

Aripiprazole, sold under the brand names Abilify and Aristada, among others, is an atypical antipsychotic. It is primarily used in the treatment of schizophrenia and bipolar disorder; other uses include as an add-on treatment in major depressive disorder and obsessive compulsive disorder (OCD), tic disorders, and irritability associated with autism.

See Antidepressant and Aripiprazole

Arrhythmia

Arrhythmias, also known as cardiac arrhythmias, are irregularities in the heartbeat, including when it is too fast or too slow.

See Antidepressant and Arrhythmia

Attention deficit hyperactivity disorder

Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterised by executive dysfunction occasioning symptoms of inattention, hyperactivity, impulsivity and emotional dysregulation that are excessive and pervasive, impairing in multiple contexts, and otherwise age-inappropriate.

See Antidepressant and Attention deficit hyperactivity disorder

Atypical antidepressant

An atypical antidepressant is any antidepressant medication that acts in a manner that is different from that of most other antidepressants. Antidepressant and atypical antidepressant are antidepressants.

See Antidepressant and Atypical antidepressant

Atypical antipsychotic

The atypical antipsychotics (AAP), also known as second generation antipsychotics (SGAs) and serotonin–dopamine antagonists (SDAs), are a group of antipsychotic drugs (antipsychotic drugs in general are also known as tranquilizers and neuroleptics, although the latter is usually reserved for the typical antipsychotics) largely introduced after the 1970s and used to treat psychiatric conditions.

See Antidepressant and Atypical antipsychotic

Atypical depression

Atypical depression is defined in the DSM-IV as depression that shares many of the typical symptoms of major depressive disorder or dysthymia but is characterized by improved mood in response to positive events. Antidepressant and Atypical depression are major depressive disorder.

See Antidepressant and Atypical depression

Augmentation (pharmacology)

Augmentation, in the context of the pharmacological management of psychiatry, refers to the combination of two or more drugs to achieve better treatment results.

See Antidepressant and Augmentation (pharmacology)

Avoidant personality disorder

Avoidant personality disorder (AvPD) or anxious personality disorder is a Cluster C personality disorder characterized by excessive social anxiety and inhibition, fear of intimacy (despite an intense desire for it), severe feelings of inadequacy and inferiority, and an overreliance on avoidance of feared stimuli (e.g.

See Antidepressant and Avoidant personality disorder

Ayahuasca

AyahuascaPronounced as in the UK and in the US.

See Antidepressant and Ayahuasca

Binge eating disorder

Binge eating disorder (BED) is an eating disorder characterized by frequent and recurrent binge eating episodes with associated negative psychological and social problems, but without the compensatory behaviors common to bulimia nervosa, OSFED, or the binge-purge subtype of anorexia nervosa.

See Antidepressant and Binge eating disorder

Biology of depression

Scientific studies have found that different brain areas show altered activity in humans with major depressive disorder (MDD), and this has encouraged advocates of various theories that seek to identify a biochemical origin of the disease, as opposed to theories that emphasize psychological or situational causes. Antidepressant and Biology of depression are major depressive disorder.

See Antidepressant and Biology of depression

Bipolar disorder

Bipolar disorder, previously known as manic depression, is a mental disorder characterized by periods of depression and periods of abnormally elevated mood that each last from days to weeks.

See Antidepressant and Bipolar disorder

Blinded experiment

In a blind or blinded experiment, information which may influence the participants of the experiment is withheld until after the experiment is complete.

See Antidepressant and Blinded experiment

Body dysmorphic disorder

Body dysmorphic disorder (BDD), also known in some contexts as dysmorphophobia, is a mental disorder defined by an overwhelming preoccupation with a perceived flaw in one's physical appearance.

See Antidepressant and Body dysmorphic disorder

Borderline personality disorder

Borderline personality disorder (BPD), also known as emotionally unstable personality disorder (EUPD), is a personality disorder characterized by a pervasive, long-term pattern of significant interpersonal relationship instability, a distorted sense of self, and intense emotional responses.

See Antidepressant and Borderline personality disorder

British Journal of Pharmacology

The British Journal of Pharmacology is a biweekly peer-reviewed medical journal covering all aspects of experimental pharmacology.

See Antidepressant and British Journal of Pharmacology

Bryan Molloy

Bryan Barnet Molloy (30 March 1939 – 20 May 2004) was a Scottish chemist, known notably for helping to invent the antidepressant Prozac, a name for fluoxetine.

See Antidepressant and Bryan Molloy

Bulimia nervosa

Bulimia nervosa, also known as simply bulimia, is an eating disorder characterized by binge eating followed by purging or fasting, and excessive concern with body shape and weight.

See Antidepressant and Bulimia nervosa

Bupropion

Bupropion, formerly called amfebutamone, and sold under the brand name Wellbutrin among others, is an atypical antidepressant primarily used to treat major depressive disorder and to support smoking cessation. Antidepressant and Bupropion are antidepressants.

See Antidepressant and Bupropion

Cardiac arrest

Cardiac arrest, also known as sudden cardiac arrest, is when the heart suddenly and unexpectedly stops beating.

See Antidepressant and Cardiac arrest

Cardiovascular disease

Cardiovascular disease (CVD) is any disease involving the heart or blood vessels.

See Antidepressant and Cardiovascular disease

Centers for Disease Control and Prevention

The Centers for Disease Control and Prevention (CDC) is the national public health agency of the United States.

See Antidepressant and Centers for Disease Control and Prevention

Chemical structure

A chemical structure of a molecule is a spatial arrangement of its atoms and their chemical bonds.

See Antidepressant and Chemical structure

Chemical synapse

Chemical synapses are biological junctions through which neurons' signals can be sent to each other and to non-neuronal cells such as those in muscles or glands.

See Antidepressant and Chemical synapse

Child and adolescent psychiatry

Child and adolescent psychiatry (or pediatric psychiatry) is a branch of psychiatry that focuses on the diagnosis, treatment, and prevention of mental disorders in children, adolescents, and their families.

See Antidepressant and Child and adolescent psychiatry

Chlorpromazine

Chlorpromazine (CPZ), marketed under the brand names Thorazine and Largactil among others, is an antipsychotic medication.

See Antidepressant and Chlorpromazine

Chronic pain

Chronic pain or chronic pain syndrome is a type of pain that is also known by other titles such as gradual burning pain, electrical pain, throbbing pain, and nauseating pain.

See Antidepressant and Chronic pain

Citalopram

Citalopram, sold under the brand name Celexa among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. Antidepressant and Citalopram are antidepressants.

See Antidepressant and Citalopram

Clinical significance

In medicine and psychology, clinical significance is the practical importance of a treatment effect—whether it has a real genuine, palpable, noticeable effect on daily life.

See Antidepressant and Clinical significance

Clinical trial

Clinical trials are prospective biomedical or behavioral research studies on human participants designed to answer specific questions about biomedical or behavioral interventions, including new treatments (such as novel vaccines, drugs, dietary choices, dietary supplements, and medical devices) and known interventions that warrant further study and comparison.

See Antidepressant and Clinical trial

Clomipramine

Clomipramine, sold under the brand name Anafranil among others, is a tricyclic antidepressant (TCA).

See Antidepressant and Clomipramine

CNS Drugs (journal)

CNS Drugs is a monthly peer-reviewed medical journal published by Adis International (Springer Nature) that covers drug treatment of psychiatric and neurological disorders.

See Antidepressant and CNS Drugs (journal)

Cochrane (organisation)

Cochrane is a British international charitable organisation formed to synthesize medical research findings to facilitate evidence-based choices about health interventions involving health professionals, patients and policy makers.

See Antidepressant and Cochrane (organisation)

Cognitive behavioral therapy

Cognitive behavioral therapy (CBT) is a form of psychotherapy that aims to reduce symptoms of various mental health conditions, primarily depression and anxiety disorders.

See Antidepressant and Cognitive behavioral therapy

Cohort study

A cohort study is a particular form of longitudinal study that samples a cohort (a group of people who share a defining characteristic, typically those who experienced a common event in a selected period, such as birth or graduation), performing a cross-section at intervals through time.

See Antidepressant and Cohort study

Cortisol

Cortisol is a steroid hormone in the glucocorticoid class of hormones and a stress hormone.

See Antidepressant and Cortisol

Cyclic compound

A cyclic compound (or ring compound) is a term for a compound in the field of chemistry in which one or more series of atoms in the compound is connected to form a ring.

See Antidepressant and Cyclic compound

David T. Wong

David T. Wong (born 1935 in Hong Kong) is a Hong Kong-born American neuroscientist.

See Antidepressant and David T. Wong

Dementia

Dementia is a syndrome associated with many neurodegenerative diseases, characterized by a general decline in cognitive abilities that affects a person's ability to perform everyday activities.

See Antidepressant and Dementia

Depression (mood)

Depression is a mental state of low mood and aversion to activity.

See Antidepressant and Depression (mood)

Depression in childhood and adolescence

Major depressive disorder, often simply referred to as depression, is a mental disorder characterized by prolonged unhappiness or irritability.

See Antidepressant and Depression in childhood and adolescence

Desvenlafaxine

Desvenlafaxine, sold under the brand name Pristiq among others, is a medication used to treat depression. Antidepressant and Desvenlafaxine are antidepressants.

See Antidepressant and Desvenlafaxine

Dextroamphetamine

Dextroamphetamine (INN:dexamfetamine) is a potent central nervous system (CNS) stimulant and enantiomer of amphetamine that is prescribed for the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy.

See Antidepressant and Dextroamphetamine

Dextromethorphan

Dextromethorphan (DXM), sold under the trade name Robitussin among others, is a cough suppressant used in many cough and cold medicines.

See Antidepressant and Dextromethorphan

Dextromethorphan/bupropion

Dextromethorphan/bupropion (DXM/BUP), sold under the brand name Auvelity, is a combination medication for the treatment of major depressive disorder (MDD). Antidepressant and Dextromethorphan/bupropion are antidepressants.

See Antidepressant and Dextromethorphan/bupropion

Diabetes

Diabetes mellitus, often known simply as diabetes, is a group of common endocrine diseases characterized by sustained high blood sugar levels.

See Antidepressant and Diabetes

Diabetic neuropathy

Diabetic neuropathy is various types of nerve damage associated with diabetes mellitus.

See Antidepressant and Diabetic neuropathy

Diamine oxidase

Diamine oxidase (DAO), also known "amine oxidase, copper-containing, 1" (AOC1), formerly called histaminase, is an enzyme involved in the metabolism, oxidation, and inactivation of histamine and other polyamines such as putrescine or spermidine.

See Antidepressant and Diamine oxidase

Dizziness

Dizziness is an imprecise term that can refer to a sense of disorientation in space, vertigo, or lightheadedness.

See Antidepressant and Dizziness

Dopamine

Dopamine (DA, a contraction of 3,4-dihydroxyphenethylamine) is a neuromodulatory molecule that plays several important roles in cells.

See Antidepressant and Dopamine

Dopamine agonist

A dopamine agonist is a compound that activates dopamine receptors.

See Antidepressant and Dopamine agonist

Dopamine reuptake inhibitor

A dopamine reuptake inhibitor (DRI) is a class of drug which acts as a reuptake inhibitor of the monoamine neurotransmitter dopamine by blocking the action of the dopamine transporter (DAT).

See Antidepressant and Dopamine reuptake inhibitor

Dopamine transporter

The dopamine transporter (DAT, also sodium-dependent dopamine transporter) is a membrane-spanning protein coded for in humans by the SLC6A3 gene (also known as DAT1), that pumps the neurotransmitter dopamine out of the synaptic cleft back into cytosol.

See Antidepressant and Dopamine transporter

Dopaminergic cell groups

Dopaminergic cell groups, DA cell groups, or dopaminergic nuclei are collections of neurons in the central nervous system that synthesize the neurotransmitter dopamine.

See Antidepressant and Dopaminergic cell groups

Dose–response relationship

The dose–response relationship, or exposure–response relationship, describes the magnitude of the response of an organism, as a function of exposure (or doses) to a stimulus or stressor (usually a chemical) after a certain exposure time.

See Antidepressant and Dose–response relationship

Drug

A drug is any chemical substance other than a nutrient or an essential dietary ingredient, which, when administered to a living organism, produces a biological effect.

See Antidepressant and Drug

Drug design

Drug design, often referred to as rational drug design or simply rational design, is the inventive process of finding new medications based on the knowledge of a biological target.

See Antidepressant and Drug design

Drug withdrawal

Drug withdrawal, drug withdrawal syndrome, or substance withdrawal syndrome, is the group of symptoms that occur upon the abrupt discontinuation or decrease in the intake of pharmaceutical or recreational drugs.

See Antidepressant and Drug withdrawal

Drug-induced QT prolongation

QT prolongation is a measure of delayed ventricular repolarisation, which means the heart muscle takes longer than normal to recharge between beats.

See Antidepressant and Drug-induced QT prolongation

Duloxetine

Duloxetine, sold under the brand name Cymbalta among others, is a medication used to treat major depressive disorder, generalized anxiety disorder, obsessive-compulsive disorder, fibromyalgia, neuropathic pain and central sensitization. Antidepressant and Duloxetine are antidepressants.

See Antidepressant and Duloxetine

Effect size

In statistics, an effect size is a value measuring the strength of the relationship between two variables in a population, or a sample-based estimate of that quantity.

See Antidepressant and Effect size

Electroconvulsive therapy

Electroconvulsive therapy (ECT) or electroshock therapy (EST) is a psychiatric treatment where a generalized seizure (without muscular convulsions) is electrically induced to manage refractory mental disorders.

See Antidepressant and Electroconvulsive therapy

Eli Lilly and Company

Eli Lilly and Company is an American pharmaceutical company headquartered in Indianapolis, Indiana, with offices in 18 countries.

See Antidepressant and Eli Lilly and Company

Emotional lability

In medicine and psychology, emotional lability is a sign or symptom typified by exaggerated changes in mood or affect in quick succession.

See Antidepressant and Emotional lability

Endogeny (biology)

Endogenous substances and processes are those that originate from within a living system such as an organism, tissue, or cell.

See Antidepressant and Endogeny (biology)

Epigenetics

In biology, epigenetics is the study of heritable traits, or a stable change of cell function, that happen without changes to the DNA sequence.

See Antidepressant and Epigenetics

Erectile dysfunction

Erectile dysfunction (ED), also referred to as impotence, is a form of sexual dysfunction in males characterized by the persistent or recurring inability to achieve or maintain a penile erection with sufficient rigidity and duration for satisfactory sexual activity.

See Antidepressant and Erectile dysfunction

Escitalopram

Escitalopram, sold under the brand names Lexapro and Cipralex, among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. Antidepressant and Escitalopram are antidepressants.

See Antidepressant and Escitalopram

Esketamine

Esketamine, sold under the brand names Spravato (for depression) and Ketanest (for anesthesia) among others, is the S(+) enantiomer of ketamine. Antidepressant and Esketamine are antidepressants.

See Antidepressant and Esketamine

Fibromyalgia

Fibromyalgia is a medical syndrome which causes chronic widespread pain, accompanied by fatigue, waking unrefreshed, and cognitive symptoms.

See Antidepressant and Fibromyalgia

Fluoxetine

Fluoxetine, sold under the brand name Prozac, among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. Antidepressant and Fluoxetine are antidepressants.

See Antidepressant and Fluoxetine

Fluvoxamine

Fluvoxamine, sold under the brand name Luvox among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. Antidepressant and Fluvoxamine are antidepressants.

See Antidepressant and Fluvoxamine

Food and Drug Administration

The United States Food and Drug Administration (FDA or US FDA) is a federal agency of the Department of Health and Human Services.

See Antidepressant and Food and Drug Administration

Frank Ayd

Frank Joseph Ayd Jr. (October 14, 1920 – March 21, 2008) was an American psychiatrist known for introducing the first antipsychotic medications into US clinical practice, being granted the first permit from the Food and Drug Administration to use Thorazine for schizophrenia.

See Antidepressant and Frank Ayd

Generalized anxiety disorder

Generalized anxiety disorder (GAD) is a mental and behavioral disorder, specifically an anxiety disorder characterized by excessive, uncontrollable and often irrational worry about events or activities.

See Antidepressant and Generalized anxiety disorder

Germany

Germany, officially the Federal Republic of Germany (FRG), is a country in Central Europe.

See Antidepressant and Germany

Ghostwriter

A ghostwriter is a person hired to write literary or journalistic works, speeches, or other texts that are putatively credited to another person as the author.

See Antidepressant and Ghostwriter

Glossary of biology

This glossary of biology terms is a list of definitions of fundamental terms and concepts used in biology, the study of life and of living organisms.

See Antidepressant and Glossary of biology

Glucocorticoid

Glucocorticoids (or, less commonly, glucocorticosteroids) are a class of corticosteroids, which are a class of steroid hormones.

See Antidepressant and Glucocorticoid

Glucuronide

A glucuronide, also known as glucuronoside, is any substance produced by linking glucuronic acid to another substance via a glycosidic bond.

See Antidepressant and Glucuronide

Glutamic acid

Glutamic acid (symbol Glu or E; the anionic form is known as glutamate) is an α-amino acid that is used by almost all living beings in the biosynthesis of proteins.

See Antidepressant and Glutamic acid

Half-life

Half-life (symbol) is the time required for a quantity (of substance) to reduce to half of its initial value.

See Antidepressant and Half-life

Hamilton Rating Scale for Depression

The Hamilton Rating Scale for Depression (HRSD), also called the Hamilton Depression Rating Scale (HDRS), sometimes also abbreviated as HAM-D, is a multiple-item questionnaire used to provide an indication of depression, and as a guide to evaluate recovery.

See Antidepressant and Hamilton Rating Scale for Depression

Headache

Headache, also known as cephalalgia, is the symptom of pain in the face, head, or neck.

See Antidepressant and Headache

Hepatotoxicity

Hepatotoxicity (from hepatic toxicity) implies chemical-driven liver damage.

See Antidepressant and Hepatotoxicity

Histamine

Histamine is an organic nitrogenous compound involved in local immune responses communication, as well as regulating physiological functions in the gut and acting as a neurotransmitter for the brain, spinal cord, and uterus.

See Antidepressant and Histamine

Histamine H1 receptor

The H1 receptor is a histamine receptor belonging to the family of rhodopsin-like G-protein-coupled receptors.

See Antidepressant and Histamine H1 receptor

Hydrazine

Hydrazine is an inorganic compound with the chemical formula.

See Antidepressant and Hydrazine

Hyperforin

Hyperforin is a phytochemical produced by some of the members of the plant genus Hypericum, notably Hypericum perforatum (St John's wort). Antidepressant and Hyperforin are antidepressants.

See Antidepressant and Hyperforin

Hypericum

Hypericum is a genus of flowering plants in the family Hypericaceae (formerly considered a subfamily of Clusiaceae).

See Antidepressant and Hypericum

Hypericum perforatum

Hypericum perforatum, commonly known as St John's wort (sometimes perforate St John's wort or common St John's wort), is a flowering plant in the family Hypericaceae. Antidepressant and Hypericum perforatum are antidepressants.

See Antidepressant and Hypericum perforatum

Hypertensive crisis

Severely elevated blood pressure (equal to or greater than 180 mmHg systolic or 120 mmHg diastolic) is referred to as a hypertensive crisis (sometimes termed malignant or accelerated hypertension), due to the high risk of complications.

See Antidepressant and Hypertensive crisis

Hypnotic

Hypnotic (from Greek Hypnos, sleep), or soporific drugs, commonly known as sleeping pills, are a class of (and umbrella term for) psychoactive drugs whose primary function is to induce sleep (or surgical anesthesiaWhen used in anesthesia to produce and maintain unconsciousness, "sleep" is metaphorical as there are no regular sleep stages or cyclical natural states; patients rarely recover from anesthesia feeling refreshed and with renewed energy.

See Antidepressant and Hypnotic

Hypomania

Hypomania (literally "under mania" or "less than mania") is a mental and behavioral disorder, characterised essentially by an apparently non-contextual elevation of mood (euphoria) that contributes to persistently disinhibited behavior.

See Antidepressant and Hypomania

Imipramine

Imipramine, sold under the brand name Tofranil, among others, is a tricyclic antidepressant (TCA) mainly used in the treatment of depression.

See Antidepressant and Imipramine

Indalpine

Indalpine (INN, BAN; brand name Upstène; developmental code name LM-5008) is a selective serotonin reuptake inhibitor (SSRI) class drug that was briefly marketed. Antidepressant and Indalpine are antidepressants.

See Antidepressant and Indalpine

Infant

An infant or baby is the very young offspring of human beings.

See Antidepressant and Infant

Inflammation

Inflammation (from inflammatio) is part of the biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or irritants.

See Antidepressant and Inflammation

Influenza-like illness

Influenza-like illness (ILI), also known as flu-like syndrome or flu-like symptoms, is a medical diagnosis of possible influenza or other illness causing a set of common symptoms.

See Antidepressant and Influenza-like illness

Intellectual disability

Intellectual disability (ID), also known as general learning disability (in the United Kingdom) and formerly mental retardation (in the United States),Rosa's Law, Pub.

See Antidepressant and Intellectual disability

International Review of Psychiatry

The International Review of Psychiatry is a bimonthly peer-reviewed medical journal published by Taylor & Francis on behalf of the Institute of Psychiatry (King's College London).

See Antidepressant and International Review of Psychiatry

Ionotropic glutamate receptor

Ionotropic glutamate receptors (iGluRs) are ligand-gated ion channels that are activated by the neurotransmitter glutamate.

See Antidepressant and Ionotropic glutamate receptor

Iproniazid

Iproniazid (Marsilid, Rivivol, Euphozid, Iprazid, Ipronid, Ipronin) is a non-selective, irreversible monoamine oxidase inhibitor (MAOI) of the hydrazine class.

See Antidepressant and Iproniazid

Irving Kirsch

Irving Kirsch (born March 7, 1943) is an American psychologist and academic.

See Antidepressant and Irving Kirsch

Irving Selikoff

Irving J. Selikoff (January 15, 1915 – May 20, 1992) was a medical researcher who in the 1960s established a link between the inhalation of asbestos particles and lung-related ailments.

See Antidepressant and Irving Selikoff

Isoniazid

Isoniazid, also known as isonicotinic acid hydrazide (INH), is an antibiotic used for the treatment of tuberculosis. Antidepressant and Isoniazid are antidepressants.

See Antidepressant and Isoniazid

Jean Delay

Jean Delay (14 November 1907, Bayonne – 29 May 1987, Paris) was a French psychiatrist, neurologist, writer, and a member of the Académie française (Chair 17).

See Antidepressant and Jean Delay

Joanna Moncrieff

Joanna Moncrieff is a British psychiatrist and academic.

See Antidepressant and Joanna Moncrieff

Ketamine

Ketamine is a dissociative anesthetic used medically for induction and maintenance of anesthesia. Antidepressant and Ketamine are antidepressants.

See Antidepressant and Ketamine

Klaus Schmiegel

Klaus Schmiegel (born June 28, 1939), is a German chemist best known for his work in organic chemistry, which led to the invention of Prozac, a widely used antidepressant.

See Antidepressant and Klaus Schmiegel

Libido

In psychology, libido (from the Latin, 'desire') is psychic drive or energy, usually conceived as sexual in nature, but sometimes conceived as including other forms of desire.

See Antidepressant and Libido

Ligand (biochemistry)

In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose.

See Antidepressant and Ligand (biochemistry)

Light therapy

Light therapy, also called phototherapy or bright light therapy is the exposure to direct sunlight or artificial light at controlled wavelengths in order to treat a variety of medical disorders, including seasonal affective disorder (SAD), circadian rhythm sleep-wake disorders, cancers, and skin wound infections.

See Antidepressant and Light therapy

List of antidepressants

This is a complete list of clinically approved prescription antidepressants throughout the world, as well as clinically approved prescription drugs used to augment antidepressants or mood stabilizers, by pharmacological and/or structural classification. Antidepressant and list of antidepressants are antidepressants.

See Antidepressant and List of antidepressants

List of investigational antidepressants

This is a list of investigational antidepressants, or antidepressants that are currently under development for clinical use in the treatment of mood disorders but are not yet approved.

See Antidepressant and List of investigational antidepressants

Lithium (medication)

Certain lithium compounds, also known as lithium salts, are used as psychiatric medication, primarily for bipolar disorder and for major depressive disorder.

See Antidepressant and Lithium (medication)

Los Angeles Times

The Los Angeles Times is a regional American daily newspaper that began publishing in Los Angeles, California in 1881.

See Antidepressant and Los Angeles Times

Maintenance therapy

Maintenance therapy is a medical therapy that is designed to help a primary treatment succeed.

See Antidepressant and Maintenance therapy

Major depressive disorder

Major depressive disorder (MDD), also known as clinical depression, is a mental disorder characterized by at least two weeks of pervasive low mood, low self-esteem, and loss of interest or pleasure in normally enjoyable activities.

See Antidepressant and Major depressive disorder

Management of depression

Management of depression is the treatment of depression that may involve a number of different therapies: medications, behavior therapy, psychotherapy, and medical devices.

See Antidepressant and Management of depression

Management of tuberculosis

Management of tuberculosis refers to techniques and procedures utilized for treating tuberculosis (TB), or simply a treatment plan for TB.

See Antidepressant and Management of tuberculosis

Mania

Mania, also known as manic syndrome, is a mental and behavioral disorder defined as a state of abnormally elevated arousal, affect, and energy level, or "a state of heightened overall activation with enhanced affective expression together with lability of affect." During a manic episode, an individual will experience rapidly changing emotions and moods, highly influenced by surrounding stimuli.

See Antidepressant and Mania

Mechanism of action

In pharmacology, the term mechanism of action (MOA) refers to the specific biochemical interaction through which a drug substance produces its pharmacological effect.

See Antidepressant and Mechanism of action

Medical prescription

A prescription, often abbreviated or Rx, is a formal communication from a physician or other registered healthcare professional to a pharmacist, authorizing them to dispense a specific prescription drug for a specific patient.

See Antidepressant and Medical prescription

Medication

A medication (also called medicament, medicine, pharmaceutical drug, medicinal drug or simply drug) is a drug used to diagnose, cure, treat, or prevent disease.

See Antidepressant and Medication

Medication discontinuation

Medication discontinuation is the ceasing of a medication treatment for a patient by either the clinician or the patient themself.

See Antidepressant and Medication discontinuation

Melancholia

Melancholia or melancholy (from µέλαινα χολή.,Burton, Bk. I, p. 147 meaning black bile) is a concept found throughout ancient, medieval, and premodern medicine in Europe that describes a condition characterized by markedly depressed mood, bodily complaints, and sometimes hallucinations and delusions.

See Antidepressant and Melancholia

Membrane protein

Membrane proteins are common proteins that are part of, or interact with, biological membranes.

See Antidepressant and Membrane protein

Menopause

Menopause, also known as the climacteric, is the time when menstrual periods permanently stop, marking the end of reproduction.

See Antidepressant and Menopause

Mesolimbic pathway

The mesolimbic pathway, sometimes referred to as the reward pathway, is a dopaminergic pathway in the brain.

See Antidepressant and Mesolimbic pathway

Meta-analysis

Meta-analysis is the statistical combination of the results of multiple studies addressing a similar research question.

See Antidepressant and Meta-analysis

Methodology

In its most common sense, methodology is the study of research methods.

See Antidepressant and Methodology

Michael P. Hengartner

Michael Pascal Hengartner is an academic psychologist at the Zurich University of Applied Sciences who has published on the subject of antidepressants and in other areas.

See Antidepressant and Michael P. Hengartner

Migraine

Migraine is a genetically influenced complex neurological disorder characterized by episodes of moderate-to-severe headache, most often unilateral and generally associated with nausea and light and sound sensitivity.

See Antidepressant and Migraine

Milnacipran

Milnacipran (trade names Ixel, Savella, Dalcipran, Toledomin) is a serotonin–norepinephrine reuptake inhibitor (SNRI) used in the clinical treatment of fibromyalgia. It is not approved for the clinical treatment of major depressive disorder in the US, but it is in other countries.

See Antidepressant and Milnacipran

Mindfulness-based cognitive therapy

Mindfulness-based cognitive therapy (MBCT) is an approach to psychotherapy that uses cognitive behavioral therapy (CBT) methods in conjunction with mindfulness meditative practices and similar psychological strategies.

See Antidepressant and Mindfulness-based cognitive therapy

Mirtazapine

Mirtazapine, sold under the brand name Remeron among others, is an atypical tetracyclic antidepressant, and as such is used primarily to treat depression.

See Antidepressant and Mirtazapine

Moclobemide

Moclobemide, sold under the brand names Amira, Aurorix, Clobemix, Depnil and Manerix among others, is a reversible inhibitor of monoamine oxidase A (RIMA) drug primarily used to treat depression and social anxiety. It is not approved for use in the United States, but is approved in other Western countries such as Canada, the UK and Australia.

See Antidepressant and Moclobemide

Modafinil

Modafinil, sold under the brand name Provigil among others, is a wakefulness-promoting medication used primarily to treat narcolepsy, a sleep disorder characterized by excessive daytime sleepiness and sudden sleep attacks.

See Antidepressant and Modafinil

Monoamine neurotransmitter

Monoamine neurotransmitters are neurotransmitters and neuromodulators that contain one amino group connected to an aromatic ring by a two-carbon chain (such as -CH2-CH2-). Examples are dopamine, norepinephrine and serotonin.

See Antidepressant and Monoamine neurotransmitter

Monoamine oxidase

Monoamine oxidases (MAO) are a family of enzymes that catalyze the oxidation of monoamines, employing oxygen to clip off their amine group.

See Antidepressant and Monoamine oxidase

Monoamine oxidase A

Monoamine oxidase A, also known as MAO-A, is an enzyme (E.C. 1.4.3.4) that in humans is encoded by the MAOA gene.

See Antidepressant and Monoamine oxidase A

Monoamine oxidase inhibitor

Monoamine oxidase inhibitors (MAOIs) are a class of drugs that inhibit the activity of one or both monoamine oxidase enzymes: monoamine oxidase A (MAO-A) and monoamine oxidase B (MAO-B). Antidepressant and monoamine oxidase inhibitor are antidepressants.

See Antidepressant and Monoamine oxidase inhibitor

Monoamine receptor

A monoamine receptor is a receptor for the monoamine neurotransmitters and/or trace amines, endogenous small-molecule signaling molecules with a monoamine structure.

See Antidepressant and Monoamine receptor

Monoamine transporter

Monoamine transporters (MATs) are proteins that function as integral plasma-membrane transporters to regulate concentrations of extracellular monoamine neurotransmitters.

See Antidepressant and Monoamine transporter

Monoaminergic

Monoaminergic means "working on monoamine neurotransmitters", which include serotonin, dopamine, norepinephrine, epinephrine, and histamine.

See Antidepressant and Monoaminergic

Montgomery–Åsberg Depression Rating Scale

The Montgomery–Åsberg Depression Rating Scale (MADRS) is a ten-item diagnostic questionnaire which mental health professionals use to measure the severity of depressive episodes in patients with mood disorders.

See Antidepressant and Montgomery–Åsberg Depression Rating Scale

Mortality rate

Mortality rate, or death rate, is a measure of the number of deaths (in general, or due to a specific cause) in a particular population, scaled to the size of that population, per unit of time.

See Antidepressant and Mortality rate

Muscarinic acetylcholine receptor

Muscarinic acetylcholine receptors, or mAChRs, are acetylcholine receptors that form G protein-coupled receptor complexes in the cell membranes of certain neurons and other cells.

See Antidepressant and Muscarinic acetylcholine receptor

Narcolepsy

Narcolepsy is a chronic neurological disorder that impairs the ability to regulate sleep–wake cycles, and specifically impacts REM (rapid eye movement) sleep.

See Antidepressant and Narcolepsy

Nathan S. Kline

Nathan Schellenberg Kline, M.D. (March 22, 1916 – February 11, 1983) was an American scientist, researcher in the field of psychology and psychiatrist best known for his work with psychopharmacologic drugs.

See Antidepressant and Nathan S. Kline

National Health Service

The National Health Service (NHS) is the umbrella term for the publicly funded healthcare systems of the United Kingdom, comprising the NHS in England, NHS Scotland and NHS Wales.

See Antidepressant and National Health Service

National Institute for Health and Care Excellence

The National Institute for Health and Care Excellence (NICE) is an executive non-departmental public body, in England, of the Department of Health and Social Care, that publishes guidelines in four areas.

See Antidepressant and National Institute for Health and Care Excellence

Nefazodone

Nefazodone, sold formerly under the brand names Serzone, Dutonin, and Nefadar among others, is an atypical antidepressant medication which is used in the treatment of depression and for other uses. Antidepressant and Nefazodone are antidepressants.

See Antidepressant and Nefazodone

Neurogenesis

Neurogenesis is the process by which nervous system cells, the neurons, are produced by neural stem cells (NSCs). This occurs in all species of animals except the porifera (sponges) and placozoans. Types of NSCs include neuroepithelial cells (NECs), radial glial cells (RGCs), basal progenitors (BPs), intermediate neuronal precursors (INPs), subventricular zone astrocytes, and subgranular zone radial astrocytes, among others.

See Antidepressant and Neurogenesis

Neuropathic pain

Neuropathic pain is pain caused by a lesion or disease of the somatosensory nervous system.

See Antidepressant and Neuropathic pain

Neurotransmission

Neurotransmission (Latin: transmissio "passage, crossing" from transmittere "send, let through") is the process by which signaling molecules called neurotransmitters are released by the axon terminal of a neuron (the presynaptic neuron), and bind to and react with the receptors on the dendrites of another neuron (the postsynaptic neuron) a short distance away.

See Antidepressant and Neurotransmission

Neurotransmitter

A neurotransmitter is a signaling molecule secreted by a neuron to affect another cell across a synapse.

See Antidepressant and Neurotransmitter

Neurotransmitter receptor

A neurotransmitter receptor (also known as a neuroreceptor) is a membrane receptor protein that is activated by a neurotransmitter.

See Antidepressant and Neurotransmitter receptor

Nitric oxide synthase

Nitric oxide synthases (NOSs) are a family of enzymes catalyzing the production of nitric oxide (NO) from L-arginine.

See Antidepressant and Nitric oxide synthase

NMDA receptor

The N-methyl-D-aspartate receptor (also known as the NMDA receptor or NMDAR), is a glutamate receptor and predominantly Ca2+ ion channel found in neurons.

See Antidepressant and NMDA receptor

NMDA receptor antagonist

NMDA receptor antagonists are a class of drugs that work to antagonize, or inhibit the action of, the ''N''-Methyl-D-aspartate receptor (NMDAR).

See Antidepressant and NMDA receptor antagonist

Non-pharmacological intervention

non-pharmacological intervention (NPI) is any type of healthcare intervention which is not primarily based on medication.

See Antidepressant and Non-pharmacological intervention

Norepinephrine

Norepinephrine (NE), also called noradrenaline (NA) or noradrenalin, is an organic chemical in the catecholamine family that functions in the brain and body as a hormone, neurotransmitter and neuromodulator.

See Antidepressant and Norepinephrine

Norepinephrine reuptake inhibitor

A norepinephrine reuptake inhibitor (NRI, NERI) or noradrenaline reuptake inhibitor or adrenergic reuptake inhibitor (ARI), is a type of drug that acts as a reuptake inhibitor for the neurotransmitters norepinephrine (noradrenaline) and epinephrine (adrenaline) by blocking the action of the norepinephrine transporter (NET).

See Antidepressant and Norepinephrine reuptake inhibitor

Norepinephrine transporter

The norepinephrine transporter (NET), also known as noradrenaline transporter (NAT), is a protein that in humans is encoded by the solute carrier family 6 member 2 (SLC6A2) gene.

See Antidepressant and Norepinephrine transporter

Norepinephrine–dopamine reuptake inhibitor

A norepinephrine–dopamine reuptake inhibitor (NDRI) is a drug used for the treatment of clinical depression, attention deficit hyperactivity disorder (ADHD), narcolepsy, and the management of Parkinson's disease.

See Antidepressant and Norepinephrine–dopamine reuptake inhibitor

Nortriptyline

Nortriptyline, sold under the brand name Aventyl, among others, is a tricyclic antidepressant.

See Antidepressant and Nortriptyline

Novartis

Novartis AG is a Swiss multinational pharmaceutical corporation based in Basel, Switzerland.

See Antidepressant and Novartis

Obsessive–compulsive disorder

Obsessive–compulsive disorder (OCD) is a mental and behavioral disorder in which an individual has intrusive thoughts (an obsession) and feels the need to perform certain routines (compulsions) repeatedly to relieve the distress caused by the obsession, to the extent where it impairs general function.

See Antidepressant and Obsessive–compulsive disorder

Odds ratio

An odds ratio (OR) is a statistic that quantifies the strength of the association between two events, A and B. The odds ratio is defined as the ratio of the odds of event A taking place in the presence of B, the and odds of A in the absence of B. Due to symmetry, odds ratio reciprocally calculates the ratio of the odds of B occurring in the presence of A, and the odds of B in the absence of A.

See Antidepressant and Odds ratio

Off-label use

Off-label use is the use of pharmaceutical drugs for an unapproved indication or in an unapproved age group, dosage, or route of administration.

See Antidepressant and Off-label use

Olanzapine

Olanzapine, sold under the brand name Zyprexa among others, is an atypical antipsychotic primarily used to treat schizophrenia and bipolar disorder.

See Antidepressant and Olanzapine

Opioid

Opioids are a class of drugs that derive from, or mimic, natural substances found in the opium poppy plant. Antidepressant and Opioid are Anaphrodisia.

See Antidepressant and Opioid

Over-the-counter drug

Over-the-counter (OTC) drugs are medicines sold directly to a consumer without a requirement for a prescription from a healthcare professional, as opposed to prescription drugs, which may be supplied only to consumers possessing a valid prescription.

See Antidepressant and Over-the-counter drug

Panic disorder

Panic disorder is a mental and behavioral disorder, specifically an anxiety disorder characterized by reoccurring unexpected panic attacks.

See Antidepressant and Panic disorder

Parkinson's disease

Parkinson's disease (PD), or simply Parkinson's, is a long-term neurodegenerative disease of mainly the central nervous system that affects both the motor and non-motor systems of the body.

See Antidepressant and Parkinson's disease

Paroxetine

Paroxetine, sold under the brand names Paxil and Seroxat among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It is used to treat major depressive disorder, obsessive-compulsive disorder, panic disorder, social anxiety disorder, post-traumatic stress disorder, generalized anxiety disorder, and premenstrual dysphoric disorder. Antidepressant and Paroxetine are antidepressants.

See Antidepressant and Paroxetine

Partial agonist

In pharmacology, partial agonists are drugs that bind to and activate a given receptor, but have only partial efficacy at the receptor relative to a full agonist.

See Antidepressant and Partial agonist

Pharmaceutical industry

The pharmaceutical industry is an industry involved in medicine that discovers, develops, produces, and markets pharmaceutical goods for use as drugs that function by being administered to (or self-administered by) patients using such medications with the goal of curing and/or preventing disease (as well as possibly alleviating symptoms of illness and/or injury).

See Antidepressant and Pharmaceutical industry

Pharmacotherapy

Pharmacotherapy, also known as pharmacological therapy or drug therapy, is defined as medical treatment that utilizes one or more pharmaceutical drugs to improve ongoing symptoms (symptomatic relief), treat the underlying condition, or act as a prevention for other diseases (prophylaxis).

See Antidepressant and Pharmacotherapy

Phenelzine

Phenelzine, sold under the brand name Nardil, among others, is a non-selective and irreversible monoamine oxidase inhibitor (MAOI) of the hydrazine class which is primarily used as an antidepressant and anxiolytic.

See Antidepressant and Phenelzine

Phenylpiperazine

1-Phenylpiperazine is a simple chemical compound featuring a phenyl group bound to a piperazine ring.

See Antidepressant and Phenylpiperazine

Pirlindole

Pirlindole (Lifril, Pyrazidol) is mainly a reversible inhibitor of monoamine oxidase A (RIMA) and secondly a SNRI which was developed and is used in Russia as an antidepressant. Antidepressant and Pirlindole are antidepressants.

See Antidepressant and Pirlindole

Placebo

A placebo is a substance or treatment which is designed to have no therapeutic value.

See Antidepressant and Placebo

Post-traumatic stress disorder

Post-traumatic stress disorder (PTSD) is a mental and behavioral disorder that develops from experiencing a traumatic event, such as sexual assault, warfare, traffic collisions, child abuse, domestic violence, or other threats on a person's life or well-being.

See Antidepressant and Post-traumatic stress disorder

Pre-eclampsia

Pre-eclampsia is a multi-system disorder specific to pregnancy, characterized by the onset of high blood pressure and often a significant amount of protein in the urine.

See Antidepressant and Pre-eclampsia

Prescription drug

A prescription drug (also prescription medication, prescription medicine or prescription-only medication) is a pharmaceutical drug that is permitted to be dispensed only to those with a medical prescription.

See Antidepressant and Prescription drug

Preventive healthcare

Preventive healthcare, or prophylaxis, is the application of healthcare measures to prevent diseases.

See Antidepressant and Preventive healthcare

Prognosis

Prognosis (Greek: πρόγνωσις "fore-knowing, foreseeing";: prognoses) is a medical term for predicting the likelihood or expected development of a disease, including whether the signs and symptoms will improve or worsen (and how quickly) or remain stable over time; expectations of quality of life, such as the ability to carry out daily activities; the potential for complications and associated health issues; and the likelihood of survival (including life expectancy).

See Antidepressant and Prognosis

Prolactin

Prolactin (PRL), also known as lactotropin and mammotropin, is a protein best known for its role in enabling mammals to produce milk.

See Antidepressant and Prolactin

Psilocybin

Psilocybin is a naturally occurring psychedelic prodrug compound produced by more than 200 species of fungi.

See Antidepressant and Psilocybin

Psychiatric hospital

Psychiatric hospitals, also known as mental health hospitals, or behavioral health hospitals are hospitals or wards specializing in the treatment of severe mental disorders, including schizophrenia, bipolar disorder, eating disorders, major depressive disorder, and others.

See Antidepressant and Psychiatric hospital

Psychiatric Times

Psychiatric Times is a medical trade publication written for an audience involved in the profession of psychiatry.

See Antidepressant and Psychiatric Times

Psychoactive drug

A psychoactive drug, mind-altering drug, or consciousness-altering drug is a chemical substance that changes brain function and results in alterations in perception, mood, consciousness, cognition, or behavior.

See Antidepressant and Psychoactive drug

Psychosis

Psychosis is a condition of the mind or psyche that results in difficulties determining what is real and what is not real.

See Antidepressant and Psychosis

Psychotherapy

Psychotherapy (also psychological therapy, talk therapy, or talking therapy) is the use of psychological methods, particularly when based on regular personal interaction, to help a person change behavior, increase happiness, and overcome problems.

See Antidepressant and Psychotherapy

Publication bias

In published academic research, publication bias occurs when the outcome of an experiment or research study biases the decision to publish or otherwise distribute it.

See Antidepressant and Publication bias

Pulmonology

Pulmonology (from Latin pulmō, -ōnis "lung" and the Greek suffix -λογία "study of"), pneumology (built on Greek πνεύμων "lung") or pneumonology is a medical specialty that deals with diseases involving the respiratory tract.

See Antidepressant and Pulmonology

Quality of life

Quality of life (QOL) is defined by the World Health Organization as "an individual's perception of their position in life in the context of the culture and value systems in which they live and in relation to their goals, expectations, standards and concerns".

See Antidepressant and Quality of life

Quetiapine

Quetiapine, sold under the brand name Seroquel among others, is an atypical antipsychotic medication used for the treatment of schizophrenia, bipolar disorder, and major depressive disorder. Antidepressant and Quetiapine are antidepressants.

See Antidepressant and Quetiapine

Randomized controlled trial

A randomized controlled trial (or randomized control trial; RCT) is a form of scientific experiment used to control factors not under direct experimental control.

See Antidepressant and Randomized controlled trial

Rating scales for depression

A depression rating scale is a psychometric instrument (tool), usually a questionnaire whose wording has been validated with experimental evidence, having descriptive words and phrases that indicate the severity of depression for a time period.

See Antidepressant and Rating scales for depression

Receptor antagonist

A receptor antagonist is a type of receptor ligand or drug that blocks or dampens a biological response by binding to and blocking a receptor rather than activating it like an agonist.

See Antidepressant and Receptor antagonist

Receptor modulator

A receptor modulator, or receptor ligand, is a general term for a substance, endogenous or exogenous, that binds to and regulates the activity of chemical receptors.

See Antidepressant and Receptor modulator

Reduced affect display

Reduced affect display, sometimes referred to as emotional blunting or emotional numbing, is a condition of reduced emotional reactivity in an individual.

See Antidepressant and Reduced affect display

Regression toward the mean

In statistics, regression toward the mean (also called regression to the mean, reversion to the mean, and reversion to mediocrity) is the phenomenon where if one sample of a random variable is extreme, the next sampling of the same random variable is likely to be closer to its mean.

See Antidepressant and Regression toward the mean

Relapse

In internal medicine, relapse or recidivism is a recurrence of a past (typically medical) condition.

See Antidepressant and Relapse

Relapse prevention

Relapse prevention (RP) is a cognitive-behavioral approach to relapse with the goal of identifying and preventing high-risk situations such as unhealthy substance use, obsessive-compulsive behavior, sexual offending, obesity, and depression.

See Antidepressant and Relapse prevention

Remission (medicine)

Remission is either the reduction or disappearance of the signs and symptoms of a disease.

See Antidepressant and Remission (medicine)

Reserpine

Reserpine is a drug that is used for the treatment of high blood pressure, usually in combination with a thiazide diuretic or vasodilator.

See Antidepressant and Reserpine

Reuptake

Reuptake is the reabsorption of a neurotransmitter by a neurotransmitter transporter located along the plasma membrane of an axon terminal (i.e., the pre-synaptic neuron at a synapse) or glial cell after it has performed its function of transmitting a neural impulse.

See Antidepressant and Reuptake

Reuptake inhibitor

Reuptake inhibitors (RIs) are a type of reuptake modulators.

See Antidepressant and Reuptake inhibitor

Rheumatoid arthritis

Rheumatoid arthritis (RA) is a long-term autoimmune disorder that primarily affects joints.

See Antidepressant and Rheumatoid arthritis

Risperidone

Risperidone, sold under the brand name Risperdal among others, is an atypical antipsychotic used to treat schizophrenia and bipolar disorder.

See Antidepressant and Risperidone

Rockland Psychiatric Center

The Rockland Psychiatric Center, originally Rockland State Hospital, in Orangeburg, New York, is a psychiatric facility for adults operated by the New York State Office of Mental Health.

See Antidepressant and Rockland Psychiatric Center

Roland Kuhn

Roland Kuhn (4 March 1912 – 10 October 2005) was a Swiss psychiatrist who discovered that the drug imipramine had antidepressant properties.

See Antidepressant and Roland Kuhn

Scientific theory

A scientific theory is an explanation of an aspect of the natural world and universe that can be (or a fortiori, that has been) repeatedly tested and corroborated in accordance with the scientific method, using accepted protocols of observation, measurement, and evaluation of results.

See Antidepressant and Scientific theory

Seaview Hospital

Seaview Hospital is a historic hospital complex in Willowbrook on Staten Island, New York.

See Antidepressant and Seaview Hospital

Secretion

Secretion is the movement of material from one point to another, such as a secreted chemical substance from a cell or gland.

See Antidepressant and Secretion

Sedative

A sedative or tranquilliser is a substance that induces sedation by reducing irritability or excitement.

See Antidepressant and Sedative

Selective serotonin reuptake inhibitor

Selective serotonin reuptake inhibitors (SSRIs) are a class of drugs that are typically used as antidepressants in the treatment of major depressive disorder, anxiety disorders, and other psychological conditions.

See Antidepressant and Selective serotonin reuptake inhibitor

Serotonin

Serotonin or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter.

See Antidepressant and Serotonin

Serotonin antagonist and reuptake inhibitor

Serotonin antagonist and reuptake inhibitors (SARIs) are a class of drugs used mainly as antidepressants, but also as anxiolytics and hypnotics. Antidepressant and Serotonin antagonist and reuptake inhibitor are antidepressants.

See Antidepressant and Serotonin antagonist and reuptake inhibitor

Serotonin modulator and stimulator

A serotonin modulator and stimulator (SMS), sometimes referred to more simply as a serotonin modulator, is a type of drug with a multimodal action specific to the serotonin neurotransmitter system. Antidepressant and serotonin modulator and stimulator are antidepressants.

See Antidepressant and Serotonin modulator and stimulator

Serotonin reuptake inhibitor

A serotonin reuptake inhibitor (SRI) is a type of drug which acts as a reuptake inhibitor of the neurotransmitter serotonin (5-hydroxytryptamine, or 5-HT) by blocking the action of the serotonin transporter (SERT).

See Antidepressant and Serotonin reuptake inhibitor

Serotonin syndrome

Serotonin syndrome (SS) is a group of symptoms that may occur with the use of certain serotonergic medications or drugs.

See Antidepressant and Serotonin syndrome

Serotonin transporter

The serotonin transporter (SERT or 5-HTT) also known as the sodium-dependent serotonin transporter and solute carrier family 6 member 4 is a protein that in humans is encoded by the SLC6A4 gene.

See Antidepressant and Serotonin transporter

Serotonin–norepinephrine reuptake inhibitor

Serotonin–norepinephrine reuptake inhibitors (SNRIs) are a class of antidepressant medications used to treat major depressive disorder (MDD), anxiety disorders, social phobia, chronic neuropathic pain, fibromyalgia syndrome (FMS), and menopausal symptoms.

See Antidepressant and Serotonin–norepinephrine reuptake inhibitor

Sertraline

Sertraline, sold under the brand name Zoloft among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. Antidepressant and Sertraline are antidepressants.

See Antidepressant and Sertraline

Sex hormone

Sex hormones, also known as sex steroids, gonadocorticoids and gonadal steroids, are steroid hormones that interact with vertebrate steroid hormone receptors.

See Antidepressant and Sex hormone

Sexual dysfunction

Sexual dysfunction is difficulty experienced by an individual or partners during any stage of normal sexual activity, including physical pleasure, desire, preference, arousal, or orgasm.

See Antidepressant and Sexual dysfunction

Side effect

In medicine, a side effect is an effect, whether therapeutic or adverse, that is unintended; although the term is predominantly employed to describe adverse effects, it can also apply to beneficial, but unintended, consequences of the use of a drug.

See Antidepressant and Side effect

Sigma receptor

Sigma receptors (σ-receptors) are protein receptors that bind ligands such as 4-PPBP (4-phenyl-1-(4-phenylbutyl) piperidine), SA 4503 (cutamesine), ditolylguanidine, dimethyltryptamine, and siramesine.

See Antidepressant and Sigma receptor

Smoking cessation

Smoking cessation, usually called quitting smoking or stopping smoking, is the process of discontinuing tobacco smoking.

See Antidepressant and Smoking cessation

Social anxiety

Social anxiety is the anxiety and fear specifically linked to being in social settings (i.e., interacting with others).

See Antidepressant and Social anxiety

Social anxiety disorder

Social anxiety disorder (SAD), also known as social phobia, is an anxiety disorder characterized by sentiments of fear and anxiety in social situations, causing considerable distress and impairing ability to function in at least some aspects of daily life.

See Antidepressant and Social anxiety disorder

Social stigma

Social stigma is the disapproval of, or discrimination against, an individual or group based on perceived characteristics that serve to distinguish them from other members of a society.

See Antidepressant and Social stigma

Spontaneous remission

Spontaneous remission, also called spontaneous healing or spontaneous regression, is an unexpected improvement or cure from a disease that usually progresses.

See Antidepressant and Spontaneous remission

STAR*D

Sequenced Treatment Alternatives to Relieve Depression (STAR*D) was a collaborative study on the treatment of depression, funded by the National Institute of Mental Health.

See Antidepressant and STAR*D

Staten Island

Staten Island is the southernmost borough of New York City, coextensive with Richmond County and situated at the southernmost point of New York.

See Antidepressant and Staten Island

Statistical significance

In statistical hypothesis testing, a result has statistical significance when a result at least as "extreme" would be very infrequent if the null hypothesis were true.

See Antidepressant and Statistical significance

Stimulant

Stimulants (also known as central nervous system stimulants, or psychostimulants, or colloquially as uppers) are a class of drugs that increase the activity of the brain. Antidepressant and stimulant are drug classes defined by psychological effects.

See Antidepressant and Stimulant

Suicidal ideation

Suicidal ideation, or suicidal thoughts, is the thought process of having ideas, or ruminations about the possibility of completing suicide. Antidepressant and suicidal ideation are major depressive disorder.

See Antidepressant and Suicidal ideation

Suicide

Suicide is the act of intentionally causing one's own death.

See Antidepressant and Suicide

Synapse

In the nervous system, a synapse is a structure that permits a neuron (or nerve cell) to pass an electrical or chemical signal to another neuron or to the target effector cell.

See Antidepressant and Synapse

Systematic review

A systematic review is a scholarly synthesis of the evidence on a clearly presented topic using critical methods to identify, define and assess research on the topic.

See Antidepressant and Systematic review

Tetracyclic antidepressant

Tetracyclic antidepressants (TeCAs) are a class of antidepressants that were first introduced in the 1970s.

See Antidepressant and Tetracyclic antidepressant

The Lancet

The Lancet is a weekly peer-reviewed general medical journal and one of the oldest of its kind.

See Antidepressant and The Lancet

Therapy

A therapy or medical treatment is the attempted remediation of a health problem, usually following a medical diagnosis.

See Antidepressant and Therapy

Thomas d'Urfey

Thomas d'Urfey (26 February 1723) was an English writer and playwright.

See Antidepressant and Thomas d'Urfey

Thyroid

The thyroid, or thyroid gland, is an endocrine gland in vertebrates.

See Antidepressant and Thyroid

Torsades de pointes

Torsades de pointes, torsade de pointes or torsades des pointes (TdP; also called torsades) (translated as "twisting of peaks") is a specific type of abnormal heart rhythm that can lead to sudden cardiac death.

See Antidepressant and Torsades de pointes

Transcranial magnetic stimulation

Transcranial magnetic stimulation (TMS) is a noninvasive form of brain stimulation in which a changing magnetic field is used to induce an electric current at a specific area of the brain through electromagnetic induction.

See Antidepressant and Transcranial magnetic stimulation

Trazodone

Trazodone, sold under many brand names, is an antidepressant medication. Antidepressant and Trazodone are antidepressants.

See Antidepressant and Trazodone

Treatment-resistant depression

Treatment-resistant depression (TRD) is a form of major depressive disorder (MDD) in which an affected person does not respond adequately to a course of appropriate antidepressant medication. Antidepressant and Treatment-resistant depression are major depressive disorder.

See Antidepressant and Treatment-resistant depression

Trichotillomania

Trichotillomania (TTM), also known as hair-pulling disorder or compulsive hair pulling, is a mental disorder characterized by a long-term urge that results in the pulling out of one's own hair.

See Antidepressant and Trichotillomania

Tricyclic antidepressant

Tricyclic antidepressants (TCAs) are a class of medications that are used primarily as antidepressants.

See Antidepressant and Tricyclic antidepressant

Triiodothyronine

Triiodothyronine, also known as T3, is a thyroid hormone.

See Antidepressant and Triiodothyronine

Tuberculosis

Tuberculosis (TB), also known colloquially as the "white death", or historically as consumption, is an infectious disease usually caused by Mycobacterium tuberculosis (MTB) bacteria.

See Antidepressant and Tuberculosis

Tyramine

Tyramine (also spelled tyramin), also known under several other names, is a naturally occurring trace amine derived from the amino acid tyrosine.

See Antidepressant and Tyramine

Umbrella review

In medical research, an umbrella review is a review of systematic reviews or meta-analyses.

See Antidepressant and Umbrella review

Venlafaxine

Venlafaxine, sold under the brand name Effexor among others, is an antidepressant medication of the serotonin–norepinephrine reuptake inhibitor (SNRI) class. Antidepressant and Venlafaxine are antidepressants.

See Antidepressant and Venlafaxine

Vilazodone

Vilazodone, sold under the brand name Viibryd among others, is a medication used to treat major depressive disorder. Antidepressant and Vilazodone are antidepressants.

See Antidepressant and Vilazodone

Vortioxetine

Vortioxetine, sold under the brand name Brintellix among others, is an antidepressant of the serotonin modulator and stimulator (SMS) class. Antidepressant and Vortioxetine are antidepressants.

See Antidepressant and Vortioxetine

Weight gain

Weight gain is an increase in body weight.

See Antidepressant and Weight gain

Wit and Mirth, or Pills to Purge Melancholy

Wit and Mirth: Or Pills to Purge Melancholy is the title of a large collection of songs by Thomas d'Urfey, published between 1698 and 1720, which in its final, six-volume edition held over 1,000 songs and poems.

See Antidepressant and Wit and Mirth, or Pills to Purge Melancholy

Xerostomia

Xerostomia, also known as dry mouth, is a subjective complaint of dryness in the mouth, which may be associated with a change in the composition of saliva, or reduced salivary flow, or have no identifiable cause.

See Antidepressant and Xerostomia

Zimelidine

Zimelidine (INN, BAN; brand names Zimeldine, Normud, Zelmid) was one of the first selective serotonin reuptake inhibitor (SSRI) antidepressants to be marketed. Antidepressant and Zimelidine are antidepressants.

See Antidepressant and Zimelidine

2007–2008 financial crisis

The 2007–2008 financial crisis, or the global financial crisis (GFC), was the most severe worldwide economic crisis since the Great Depression.

See Antidepressant and 2007–2008 financial crisis

5-HT receptor

5-HT receptors, 5-hydroxytryptamine receptors, or serotonin receptors, are a group of G protein-coupled receptor and ligand-gated ion channels found in the central and peripheral nervous systems.

See Antidepressant and 5-HT receptor

5-HT1A receptor

The serotonin 1A receptor (or 5-HT1A receptor) is a subtype of serotonin receptors, or 5-HT receptors, that binds serotonin, also known as 5-HT, a neurotransmitter.

See Antidepressant and 5-HT1A receptor

5-HT2 receptor

The 5-HT2 receptors are a subfamily of 5-HT receptors that bind the endogenous neurotransmitter serotonin (5-hydroxytryptamine, 5-HT).

See Antidepressant and 5-HT2 receptor

5-HT2A receptor

The 5-HT2A receptor is a subtype of the 5-HT2 receptor that belongs to the serotonin receptor family and is a G protein-coupled receptor (GPCR).

See Antidepressant and 5-HT2A receptor

5-HT3 receptor

The 5-HT3 receptor belongs to the Cys-loop superfamily of ligand-gated ion channels (LGICs) and therefore differs structurally and functionally from all other 5-HT receptors (5-hydroxytryptamine, or serotonin receptors) which are G protein-coupled receptors.

See Antidepressant and 5-HT3 receptor

5-HT7 receptor

The 5-HT7 receptor is a member of the GPCR superfamily of cell surface receptors and is activated by the neurotransmitter serotonin (5-hydroxytryptamine, 5-HT).

See Antidepressant and 5-HT7 receptor

See also

Anaphrodisia

• Alcohol (drug)
• Anaphrodisiac
• Antiandrogen
• Antidepressant
• Opioid
• Pharmacology of ethanol
• Tobacco
• Tropaeolum tuberosum
• Vitex agnus-castus

Drug classes defined by psychological effects

• Anaphrodisiac
• Antidepressant
• Antipsychotic
• Anxiogenic
• Anxiolytic
• Aphrodisiac
• Deliriant
• Dissociative
• Entheogen
• Eugeroic
• Hallucinogen
• History of entheogenic drugs
• Mood stabilizer
• Nootropic
• Psychedelic drug
• Psycholeptic
• Psychotomimetism
• Stimulant

Major depressive disorder

• Anhedonia
• Animal models of depression
• Antenatal depression
• Antidepressant
• Anxiety and Depression Association of America
• Anxiety/aggression-driven depression
• Atypical depression
• Biology of depression
• Catatonic depression
• Differential diagnoses of depression
• Double depression
• Endogenous depression
• Epidemiology of depression
• Epigenetics of depression
• Evolutionary approaches to postpartum depression
• History of depression
• Kindling hypothesis of depression
• Late life depression
• Major depressive disorder
• Major depressive episode
• Melancholic depression
• Neurogenesis hypothesis of depression
• Neurotrophic hypothesis of depression
• Post-stroke depression
• Psychotic depression
• Seasonal affective disorder
• Self-criticism
• Social predictors of depression
• Suicidal ideation
• Treatment-resistant depression

References

[1] https://en.wikipedia.org/wiki/Antidepressant

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