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32 relations: Adaptive immune system, Antigen, Antigen presentation, Antigen processing, Artificial antigen presenting cells, Autoimmune disease, B cell, Beta-2 microglobulin, Cancer, CD1, CD28, CD40 (protein), Cell (biology), Cross-presentation, Cytotoxic T cell, Dendritic cell, Epitope, IMP321, Lipid, Lymph node, Lymphatic vessel, Macrophage, Major histocompatibility complex, Natural killer cell, Pattern recognition receptor, Peripheral tolerance, Phagocytosis, Receptor-mediated endocytosis, T cell, T helper cell, T-cell receptor, The Proteolysis Map.
Adaptive immune system
The adaptive immune system, also known as the acquired immune system or, more rarely, as the specific immune system, is a subsystem of the overall immune system that is composed of highly specialized, systemic cells and processes that eliminate pathogens or prevent their growth.
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Antigen
In immunology, an antigen is a molecule capable of inducing an immune response (to produce an antibody) in the host organism.
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Antigen presentation
Antigen presentation describes a vital immune process which is essential for T cell immune response triggering.
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Antigen processing
Antigen processing is an immunological process that prepares antigens for presentation to special cells of the immune system called T lymphocytes.
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Artificial antigen presenting cells
Artificial antigen presenting cells (aAPCs) are a new technology and approach to cancer immunotherapy.
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Autoimmune disease
An autoimmune disease is a condition arising from an abnormal immune response to a normal body part.
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B cell
B cells, also known as B lymphocytes, are a type of white blood cell of the lymphocyte subtype.
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Beta-2 microglobulin
β2 microglobulin also known as B2M is a component of MHC class I molecules, MHC class I molecules have α1, α2, and α3 proteins which are present on all nucleated cells (excludes red blood cells).
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Cancer
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.
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CD1
CD1 (cluster of differentiation 1) is a family of glycoproteins expressed on the surface of various human antigen-presenting cells.
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CD28
CD28 (Cluster of Differentiation 28) is one of the proteins expressed on T cells that provide co-stimulatory signals required for T cell activation and survival.
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CD40 (protein)
Cluster of differentiation 40, CD40 is a costimulatory protein found on antigen presenting cells and is required for their activation.
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Cell (biology)
The cell (from Latin cella, meaning "small room") is the basic structural, functional, and biological unit of all known living organisms.
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Cross-presentation
Cross-presentation is the ability of certain antigen-presenting cells to take up, process and present extracellular antigens with MHC class I molecules to CD8 T cells (cytotoxic T cells).
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Cytotoxic T cell
A cytotoxic T cell (also known as TC, cytotoxic T lymphocyte, CTL, T-killer cell, cytolytic T cell, CD8+ T-cell or killer T cell) is a T lymphocyte (a type of white blood cell) that kills cancer cells, cells that are infected (particularly with viruses), or cells that are damaged in other ways.
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Dendritic cell
Dendritic cells (DCs) are antigen-presenting cells (also known as accessory cells) of the mammalian immune system.
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Epitope
An epitope, also known as antigenic determinant, is the part of an antigen that is recognized by the immune system, specifically by antibodies, B cells, or T cells.
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IMP321
IMP321 is a large molecule cancer drug being developed by the clinical stage biotechnology company Prima BioMed (Nasdaq: IMMP).
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Lipid
In biology and biochemistry, a lipid is a biomolecule that is soluble in nonpolar solvents.
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Lymph node
A lymph node or lymph gland is an ovoid or kidney-shaped organ of the lymphatic system, and of the adaptive immune system, that is widely present throughout the body.
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Lymphatic vessel
The lymphatic vessels (or lymph vessels or lymphatics) are thin-walled vessels structured like blood vessels, that carry lymph.
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Macrophage
Macrophages (big eaters, from Greek μακρός (makrós).
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Major histocompatibility complex
The major histocompatibility complex (MHC) is a set of cell surface proteins essential for the acquired immune system to recognize foreign molecules in vertebrates, which in turn determines histocompatibility.
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Natural killer cell
Natural killer cells or NK cells are a type of cytotoxic lymphocyte critical to the innate immune system.
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Pattern recognition receptor
Pattern recognition receptors (PRRs) play a crucial role in the proper function of the innate immune system.
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Peripheral tolerance
Peripheral tolerance is the second branch of immunological tolerance, after central tolerance.
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Phagocytosis
In cell biology, phagocytosis is the process by which a cell—often a phagocyte or a protist—engulfs a solid particle to form an internal compartment known as a phagosome.
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Receptor-mediated endocytosis
Receptor-mediated endocytosis (RME), also called clathrin-mediated endocytosis, is a process by which cells absorb metabolites, hormones, other proteins – and in some cases viruses – by the inward budding of plasma membrane vesicles containing proteins with receptor sites specific to the molecules being absorbed (endocytosis).
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T cell
A T cell, or T lymphocyte, is a type of lymphocyte (a subtype of white blood cell) that plays a central role in cell-mediated immunity.
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T helper cell
The T helper cells (Th cells) are a type of T cell that play an important role in the immune system, particularly in the adaptive immune system.
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T-cell receptor
The T-cell receptor, or TCR, is a molecule found on the surface of T cells, or T lymphocytes, that is responsible for recognizing fragments of antigen as peptides bound to major histocompatibility complex (MHC) molecules.
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The Proteolysis Map
The Proteolysis MAP (PMAP) is an integrated web resource focused on proteases.
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References
[1] https://en.wikipedia.org/wiki/Antigen-presenting_cell
