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13 relations: Arachidonate 5-lipoxygenase, Arachidonic acid, Chemotaxis, Leukotriene A4, Leukotriene B4, Leukotriene C4, Leukotriene D4, Leukotriene E4, Lipoxin, Lipoxygenase, Specialized pro-resolving mediators, 5-Hydroxyeicosatetraenoic acid, 5-oxo-eicosatetraenoic acid.
Arachidonate 5-lipoxygenase
Arachidonate 5-lipoxygenase, also known as ALOX5, 5-lipoxygenase, 5-LOX, or 5-LO, is a non-heme iron-containing enzyme (EC 1.13.11.34) that in humans is encoded by the ALOX5 gene.
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Arachidonic acid
Arachidonic acid (AA, sometimes ARA) is a polyunsaturated omega-6 fatty acid 20:4(ω-6).
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Chemotaxis
Chemotaxis (from chemo- + taxis) is the movement of an organism in response to a chemical stimulus.
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Leukotriene A4
Leukotriene A4 is a leukotriene.
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Leukotriene B4
Leukotriene B4 (LTB4) is a leukotriene involved in inflammation.
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Leukotriene C4
Leukotriene C4 (LTC4) is a leukotriene.
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Leukotriene D4
Leukotriene D4 (LTD4) is one of the leukotrienes.
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Leukotriene E4
Leukotriene E4 (LTE4) is a cysteinyl leukotriene involved in inflammation.
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Lipoxin
Lipoxins (LXs or Lxs), an acronym for lipoxygenase interaction products, are bioactive autacoid metabolites of arachidonic acid made by various cell types.
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Lipoxygenase
Lipoxygenases are a family of (non-heme), iron-containing enzymes most of which catalyze the dioxygenation of polyunsaturated fatty acids in lipids containing a cis,cis-1,4- pentadiene into cell signaling agents that serve diverse roles as autocrine signals that regulate the function of their parent cells, paracrine signals that regulate the function of nearby cells, and endocrine signals that regulate the function of distant cells.
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Specialized pro-resolving mediators
Specialized pro-resolving mediators (SPM, also termed specialized proresolving mediators) are a large and growing class of cell signaling molecules formed in cells by the metabolism of polyunsaturated fatty acids (PUFA) by one or a combination of lipoxygenase, cyclooxygenase, and cytochrome P450 monooxygenase enzymes.
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5-Hydroxyeicosatetraenoic acid
5-Hydroxyeicosatetraenoic acid (5-HETE, 5(S)-HETE, or 5S-HETE) is an eicosanoid, i.e. a metabolite of arachidonic acid.
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5-oxo-eicosatetraenoic acid
5-Oxo-eicosatetraenoic acid (i.e. 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid; also termed 5-oxo-ETE and 5-oxoETE) is a Nonclassic eicosanoid metabolite of arachidonic acid and the most potent naturally occurring member of the 5-HETE family of cell signaling agents.
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Redirects here:
5-HPETE, 5-hydroperoxyeicosatetraenoic acid.
References
[1] https://en.wikipedia.org/wiki/Arachidonic_acid_5-hydroperoxide
