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32 relations: Accelerated approval (FDA), Bladder cancer, Breast cancer, Cancer immunotherapy, CD80, Chemotherapy, Clinical endpoint, Clinical trial, Cytotoxic T cell, Fast track (FDA), Fatigue, Food and Drug Administration, Genentech, Hoffmann-La Roche, Immune checkpoint, Immunoglobulin G, Infection, Isotype (immunology), Melanoma, Monoclonal antibody, Nausea, Neoplasm, Non-small-cell lung carcinoma, PD-L1, Programmed cell death protein 1, Renal cell carcinoma, Response rate (medicine), Reuters, Survival rate, Transitional cell carcinoma, Triple-negative breast cancer, Urinary tract infection.
Accelerated approval (FDA)
The United States Food and Drug Administration (FDA) initiated the FDA Accelerated Approval Program in 1992 to allow faster approval of drugs for serious conditions that fill an unmet medical need.
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Bladder cancer
Bladder cancer is any of several types of cancer arising from the tissues of the urinary bladder.
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Breast cancer
Breast cancer is cancer that develops from breast tissue.
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Cancer immunotherapy
Cancer immunotherapy (sometimes called immuno-oncology, abbreviated IO) is the use of the immune system to treat cancer.
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CD80
Cluster of differentiation 80 (also CD80 and B7-1) is a protein found on dendritic cells, activated B cells and monocytes that provides a costimulatory signal necessary for T cell activation and survival.
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Chemotherapy
Chemotherapy (often abbreviated to chemo and sometimes CTX or CTx) is a type of cancer treatment that uses one or more anti-cancer drugs (chemotherapeutic agents) as part of a standardized chemotherapy regimen.
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Clinical endpoint
In a clinical research trial, a clinical endpoint generally refers to occurrence of a disease, symptom, sign or laboratory abnormality that constitutes one of the target outcomes of the trial, but may also refer to any such disease or sign that strongly motivates the withdrawal of that individual or entity from the trial, then often termed humane (clinical) endpoint.
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Clinical trial
Clinical trials are experiments or observations done in clinical research.
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Cytotoxic T cell
A cytotoxic T cell (also known as TC, cytotoxic T lymphocyte, CTL, T-killer cell, cytolytic T cell, CD8+ T-cell or killer T cell) is a T lymphocyte (a type of white blood cell) that kills cancer cells, cells that are infected (particularly with viruses), or cells that are damaged in other ways.
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Fast track (FDA)
Fast Track is a designation by the United States Food and Drug Administration (FDA) of an investigational drug for expedited review to facilitate development of drugs which treat a serious or life-threatening condition and fill an unmet medical need.
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Fatigue
Fatigue is a subjective feeling of tiredness that has a gradual onset.
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Food and Drug Administration
The Food and Drug Administration (FDA or USFDA) is a federal agency of the United States Department of Health and Human Services, one of the United States federal executive departments.
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Genentech
Genentech, Inc., is a biotechnology corporation which became a subsidiary of Roche in 2009.
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Hoffmann-La Roche
F.
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Immune checkpoint
Immune checkpoints are regulators of the immune system.
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Immunoglobulin G
Immunoglobulin G (IgG) is a type of antibody.
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Infection
Infection is the invasion of an organism's body tissues by disease-causing agents, their multiplication, and the reaction of host tissues to the infectious agents and the toxins they produce.
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Isotype (immunology)
In immunology, the immunoglobulin (Ig) isotype (class) is encoded by the constant region segments of the immunoglobulin gene which form the Fc portion of an antibody.
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Melanoma
Melanoma, also known as malignant melanoma, is a type of cancer that develops from the pigment-containing cells known as melanocytes.
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Monoclonal antibody
Monoclonal antibodies (mAb or moAb) are antibodies that are made by identical immune cells that are all clones of a unique parent cell.
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Nausea
Nausea or queasiness is an unpleasant sense of unease, discomfort, and revulsion towards food.
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Neoplasm
Neoplasia is a type of abnormal and excessive growth of tissue.
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Non-small-cell lung carcinoma
Non-small-cell lung carcinoma (NSCLC) is any type of epithelial lung cancer other than small cell lung carcinoma (SCLC).
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PD-L1
Programmed death-ligand 1 (PD-L1) also known as cluster of differentiation 274 (CD274) or B7 homolog 1 (B7-H1) is a protein that in humans is encoded by the CD274 gene.
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Programmed cell death protein 1
Programmed cell death protein 1, also known as PD-1 and CD279 (cluster of differentiation 279), is a protein found on the surface of cells that has a role in regulating the immune system's response to the cells of the human body by down-regulating the immune system and promoting self tolerance by suppressing T cell inflammatory activity.
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Renal cell carcinoma
Renal cell carcinoma (RCC) is a kidney cancer that originates in the lining of the proximal convoluted tubule, a part of the very small tubes in the kidney that transport primary urine.
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Response rate (medicine)
In medicine, a response rate is the percentage of patients whose cancer shrinks or disappears after treatment.
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Reuters
Reuters is an international news agency headquartered in London, United Kingdom.
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Survival rate
Survival rate is a part of survival analysis.
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Transitional cell carcinoma
Transitional cell carcinoma, also urothelial carcinoma, is a type of cancer that typically occurs in the urinary system.
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Triple-negative breast cancer
Triple-negative breast cancer (sometimes abbreviated TNBC) refers to any breast cancer that does not express the genes for estrogen receptor (ER), progesterone receptor (PR) and Her2/neu.
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Urinary tract infection
A urinary tract infection (UTI) is an infection that affects part of the urinary tract.
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References
[1] https://en.wikipedia.org/wiki/Atezolizumab
