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ATX-II

Index ATX-II

ATX-II, also known as neurotoxin 2, Av2, Anemonia viridis toxin 2 or δ-AITX-Avd1c, is a neurotoxin derived from the venom of the sea anemone Anemonia sulcata. [1]

28 relations: Anemonia sulcata, Anthopleura, BcIII, Bunodosoma, Carcinus maenas, Cardiac muscle, Cardiotoxicity, Cnidocyte, Condylactis aurantiaca, Crayfish, Crustacean, Dissociation constant, Disulfide, EC50, ExPASy, Group A nerve fiber, Myelin, Myocyte, Nav1.1, Nav1.2, Neurotoxicity, Neurotoxin, Scorpion toxin, Sea anemone, Sea anemone neurotoxin, Snakelocks anemone, Sodium channel, Voltage-gated ion channel.

Anemonia sulcata

Anemonia sulcata, or Mediterranean snakelocks sea anemone, is a species of sea anemone in the family Actiniidae.

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Anthopleura

Anthopleura is a genus of sea anemones, of the family Actiniidae.

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BcIII

BcIII is a polypeptide sea anemone neurotoxin isolated from Bunodosoma caissarum.

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Bunodosoma

Bunodosoma is a genus of sea anemones in the family Actiniidae.

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Carcinus maenas

Carcinus maenas is a common littoral crab.

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Cardiac muscle

Cardiac muscle (heart muscle) is one of the three major types of muscle, the others being skeletal and smooth muscle.

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Cardiotoxicity

Cardiotoxicity is the occurrence of heart electrophysiology dysfunction or muscle damage.

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Cnidocyte

A cnidocyte (also known as a cnidoblast or nematocyte) is an explosive cell containing one giant secretory organelle or cnida (plural cnidae) that defines the phylum Cnidaria (corals, sea anemones, hydrae, jellyfish, etc.). Cnidae are used for prey capture and defense from predators.

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Condylactis aurantiaca

Condylactis aurantiaca, common name golden anemone, is a species of sea anemone in the family Actiniidae.

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Crayfish

Crayfish, also known as crawfish, crawdads, crawldads, freshwater lobsters, mountain lobsters, mudbugs or yabbies, are freshwater crustaceans resembling small lobsters, to which they are related; taxonomically, they are members of the superfamilies Astacoidea and Parastacoidea.

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Crustacean

Crustaceans (Crustacea) form a large, diverse arthropod taxon which includes such familiar animals as crabs, lobsters, crayfish, shrimp, krill, woodlice, and barnacles.

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Dissociation constant

In chemistry, biochemistry, and pharmacology, a dissociation constant (K_d) is a specific type of equilibrium constant that measures the propensity of a larger object to separate (dissociate) reversibly into smaller components, as when a complex falls apart into its component molecules, or when a salt splits up into its component ions.

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Disulfide

In chemistry, a disulfide refers to a functional group with the structure R−S−S−R′.

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EC50

Half maximal effective concentration (EC50) refers to the concentration of a drug, antibody or toxicant which induces a response halfway between the baseline and maximum after a specified exposure time.

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ExPASy

ExPASy is a bioinformatics resource portal operated by the SIB Swiss Institute of Bioinformatics and in particular the SIB Web Team.

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Group A nerve fiber

Group A nerve fibers are one of the three classes of nerve fiber as generally classified by Erlanger and Gasser.

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Myelin

Myelin is a lipid-rich substance that surrounds the axon of some nerve cells, forming an electrically insulating layer.

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Myocyte

A myocyte (also known as a muscle cell) is the type of cell found in muscle tissue.

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Nav1.1

Nav1.1, also known as the sodium channel, voltage-gated, type I, alpha subunit (SCN1A), is a protein which in humans is encoded by the SCN1A gene.

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Nav1.2

Navα1.2, also known as the sodium channel, voltage-gated, type II, alpha subunit is a protein that in humans is encoded by the SCN2A gene.

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Neurotoxicity

Neurotoxicity is a form of toxicity in which a biological, chemical, or physical agent produces an adverse effect on the structure or function of the central and/or peripheral nervous system.

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Neurotoxin

Neurotoxins are toxins that are poisonous or destructive to nerve tissue (causing neurotoxicity).

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Scorpion toxin

Scorpion toxins are proteins found in the venom of scorpions.

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Sea anemone

Sea anemones are a group of marine, predatory animals of the order Actiniaria.

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Sea anemone neurotoxin

Sea anemone neurotoxin is the name given to neurotoxins produced by sea anemones with related structure and function.

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Snakelocks anemone

The snakelocks anemone (Anemonia viridis) is a sea anemone found in the eastern Atlantic Ocean to the Mediterranean Sea.

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Sodium channel

Sodium channels are integral membrane proteins that form ion channels, conducting sodium ions (Na+) through a cell's plasma membrane.

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Voltage-gated ion channel

Voltage-gated ion channels are a class of transmembrane proteins that form ion channels that are activated by changes in the electrical membrane potential near the channel.

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Redirects here:

Anemonia viridis toxin 2, Av2, Neurotoxin 2, Δ-AITX-Avd1c.

References

[1] https://en.wikipedia.org/wiki/ATX-II

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