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Beta-2 microglobulin

Index Beta-2 microglobulin

β2 microglobulin also known as B2M is a component of MHC class I molecules, MHC class I molecules have α1, α2, and α3 proteins which are present on all nucleated cells (excludes red blood cells). [1]

21 relations: Alloimmunity, Amyloid, CD1, CD8, Enterocyte, Ferroportin, Gene, Haemodialysis-associated amyloidosis, Hemodialysis, Hepcidin, HFE (gene), Iron overload, Liver, Lymphoma, Macrophage, MHC class I, Monoclonal gammopathy of undetermined significance, Multiple myeloma, Protein, Red blood cell, Transmembrane protein.

Alloimmunity

Alloimmunity (sometimes called isoimmunity) is an immune response to nonself antigens from members of the same species, which are called alloantigens or isoantigens.

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Amyloid

Amyloids are aggregates of proteins that become folded into a shape that allows many copies of that protein to stick together forming fibrils.

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CD1

CD1 (cluster of differentiation 1) is a family of glycoproteins expressed on the surface of various human antigen-presenting cells.

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CD8

CD8 (cluster of differentiation 8) is a transmembrane glycoprotein that serves as a co-receptor for the T cell receptor (TCR).

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Enterocyte

Enterocytes, or intestinal absorptive cells, are simple columnar epithelial cells found in the small intestine.

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Ferroportin

Ferroportin-1, also known as solute carrier family 40 member 1 (SLC40A1) or iron-regulated transporter 1 (IREG1), is a protein that in humans is encoded by the SLC40A1 gene, and is part of the Ferroportin (Fpn) Family.

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Gene

In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.

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Haemodialysis-associated amyloidosis

Haemodialysis-associated amyloidosis is a form of systemic amyloidosis associated with chronic kidney failure.

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Hemodialysis

Hemodialysis, also spelled haemodialysis, commonly called kidney dialysis or simply dialysis, is a process of purifying the blood of a person whose kidneys are not working normally.

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Hepcidin

Hepcidin is a protein that in humans is encoded by the HAMP gene.

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HFE (gene)

Human hemochromatosis protein also known as the HFE protein is a protein which in humans is encoded by the HFE gene.

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Iron overload

Iron overload (variously known as haemochromatosis, hemochromatosis, hemochromocytosis, Celtic curse, Irish illness, British gene, Scottish sickness and bronzing diabetes) indicates accumulation of iron in the body from any cause.

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Liver

The liver, an organ only found in vertebrates, detoxifies various metabolites, synthesizes proteins, and produces biochemicals necessary for digestion.

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Lymphoma

Lymphoma is a group of blood cancers that develop from lymphocytes (a type of white blood cell).

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Macrophage

Macrophages (big eaters, from Greek μακρός (makrós).

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MHC class I

MHC class I molecules are one of two primary classes of major histocompatibility complex (MHC) molecules (the other being MHC class II) and are found on the cell surface of all nucleated cells in the bodies of jawed vertebrates.

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Monoclonal gammopathy of undetermined significance

Monoclonal gammopathy of undetermined significance (MGUS, unknown or uncertain may be substituted for undetermined), formerly benign monoclonal gammopathy, is a condition in which an abnormal immunoglobin protein (known as a paraprotein) is found in the blood during standard laboratory blood tests.

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Multiple myeloma

Multiple myeloma, also known as plasma cell myeloma, is a cancer of plasma cells, a type of white blood cell normally responsible for producing antibodies.

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Protein

Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.

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Red blood cell

Red blood cells-- also known as RBCs, red cells, red blood corpuscles, haematids, erythroid cells or erythrocytes (from Greek erythros for "red" and kytos for "hollow vessel", with -cyte translated as "cell" in modern usage), are the most common type of blood cell and the vertebrate's principal means of delivering oxygen (O2) to the body tissues—via blood flow through the circulatory system.

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Transmembrane protein

A transmembrane protein (TP) is a type of integral membrane protein that spans the entirety of the biological membrane to which it is permanently attached.

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Redirects here:

B2 microglobulin, B2M (gene), Beta 2 microglobulin, Beta 2-microglobulin, Beta-2-microglobulin, Beta-microglobulin, Beta2 microglobulin, Β2 microglobulin, Β2-Microglobulin.

References

[1] https://en.wikipedia.org/wiki/Beta-2_microglobulin

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