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119 relations: Action potential, Adenosine triphosphate, Afterhyperpolarization, Agonist, Alcoholism, Alternative splicing, American Journal of Psychiatry, Angiotensin, Arachidonic acid, Asparagine, Aspartic acid, Asthma, Astrocyte, Atherosclerosis, Autism spectrum, Binding site, Blood pressure, Brain, Bristol-Myers Squibb, C-terminus, Calcium, Calcium-activated potassium channel, Calcium-activated potassium channel subunit alpha-1, Cancer, Carbon monoxide, Carbonyl group, Cell cycle, Cell membrane, Central nervous system, Cerebellum, Chronic pain, Circadian rhythm, Circulatory system, Cognition, Conformational change, Coronary circulation, Dendrite, Diabetes mellitus, Dyskinesia, Electrostatics, Endocrine system, Epilepsy, Epileptic seizure, Estrogen, Fetus, FMR1, Fragile X syndrome, Gaseous signaling molecules, Gene, Glucose, ..., Glutamine, Goodwin & Company, Hearing, Hypertension, Hypoxia (medical), Intracellular, Ionic conductivity (solid state), Ischemia, KCNMB1, KCNMB2, KCNMB3, KCNMB4, Kidney, Knockout mouse, Ligand, Ligand-gated ion channel, Magnesium, Major depressive disorder, Membrane potential, Memory, Messenger RNA, Methionine sulfoxide, Microglia, Modulation, Monomer, Motor coordination, Mouse, Mutation, Neoplasm, Neuron, Neurotransmission, Neurotransmitter, Organ transplantation, Orphanet Journal of Rare Diseases, Overactive bladder, Overexcitability, Oxidative stress, Oxygen, Pathophysiology, Pharmacology, Phosphorylation, Physiology, Placebo, Potassium, Potassium channel, Properties of water, Protein, Protein kinase C, Protein phosphatase 1, Pulmonary hypertension, Purkinje cell, Repolarization, Resting potential, Schizophrenia, Sensor, Side chain, Smooth muscle tissue, Stroke, Suprachiasmatic nucleus, Synergy, Temporal lobe, Tetrameric protein, Transmembrane domain, Transmembrane protein, Uterus, Vascular resistance, Voltage-gated ion channel, Voltage-gated potassium channel, X-ray crystallography. Expand index (69 more) »
Action potential
In physiology, an action potential occurs when the membrane potential of a specific axon location rapidly rises and falls: this depolarisation then causes adjacent locations to similarly depolarise.
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Adenosine triphosphate
Adenosine triphosphate (ATP) is a complex organic chemical that participates in many processes.
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Afterhyperpolarization
Afterhyperpolarization, or AHP, is the hyperpolarizing phase of a neuron's action potential where the cell's membrane potential falls below the normal resting potential.
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Agonist
An agonist is a chemical that binds to a receptor and activates the receptor to produce a biological response.
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Alcoholism
Alcoholism, also known as alcohol use disorder (AUD), is a broad term for any drinking of alcohol that results in mental or physical health problems.
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Alternative splicing
Alternative splicing, or differential splicing, is a regulated process during gene expression that results in a single gene coding for multiple proteins.
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American Journal of Psychiatry
The American Journal of Psychiatry is a monthly peer-reviewed medical journal covering all aspects of psychiatry and the official journal of the American Psychiatric Association.
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Angiotensin
Angiotensin is a peptide hormone that causes vasoconstriction and an increase in blood pressure.
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Arachidonic acid
Arachidonic acid (AA, sometimes ARA) is a polyunsaturated omega-6 fatty acid 20:4(ω-6).
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Asparagine
Asparagine (symbol Asn or N), is an α-amino acid that is used in the biosynthesis of proteins.
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Aspartic acid
Aspartic acid (symbol Asp or D; salts known as aspartates), is an α-amino acid that is used in the biosynthesis of proteins.
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Asthma
Asthma is a common long-term inflammatory disease of the airways of the lungs.
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Astrocyte
Astrocytes (Astro from Greek astron.
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Atherosclerosis
Atherosclerosis is a disease in which the inside of an artery narrows due to the build up of plaque.
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Autism spectrum
Autism spectrum, also known as autism spectrum disorder (ASD), is a range of conditions classified as neurodevelopmental disorders.
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Binding site
In biochemistry, a binding site is a region on a protein or piece of DNA or RNA to which ligands (specific molecules and/or ions) may form a chemical bond.
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Blood pressure
Blood pressure (BP) is the pressure of circulating blood on the walls of blood vessels.
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Brain
The brain is an organ that serves as the center of the nervous system in all vertebrate and most invertebrate animals.
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Bristol-Myers Squibb
Bristol-Myers Squibb (BMS) is an American pharmaceutical company, headquartered in New York City.
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C-terminus
The C-terminus (also known as the carboxyl-terminus, carboxy-terminus, C-terminal tail, C-terminal end, or COOH-terminus) is the end of an amino acid chain (protein or polypeptide), terminated by a free carboxyl group (-COOH).
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Calcium
Calcium is a chemical element with symbol Ca and atomic number 20.
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Calcium-activated potassium channel
Calcium-activated potassium channels are potassium channels gated by calcium, or that are structurally or phylogenetically related to calcium gated channels.
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Calcium-activated potassium channel subunit alpha-1
Calcium-activated potassium channel subunit alpha-1 also known as large conductance calcium-activated potassium channel, subfamily M, alpha member 1 (KCa1.1), or BK for short, is a voltage gated potassium channel encoded by the KCNMA1 gene and characterized by their large conductance of potassium ions (K+) through cell membranes.
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Cancer
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.
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Carbon monoxide
Carbon monoxide (CO) is a colorless, odorless, and tasteless gas that is slightly less dense than air.
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Carbonyl group
In organic chemistry, a carbonyl group is a functional group composed of a carbon atom double-bonded to an oxygen atom: C.
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Cell cycle
The cell cycle or cell-division cycle is the series of events that take place in a cell leading to its division and duplication of its DNA (DNA replication) to produce two daughter cells.
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Cell membrane
The cell membrane (also known as the plasma membrane or cytoplasmic membrane, and historically referred to as the plasmalemma) is a biological membrane that separates the interior of all cells from the outside environment (the extracellular space).
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Central nervous system
The central nervous system (CNS) is the part of the nervous system consisting of the brain and spinal cord.
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Cerebellum
The cerebellum (Latin for "little brain") is a major feature of the hindbrain of all vertebrates.
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Chronic pain
Chronic pain is pain that lasts a long time.
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Circadian rhythm
A circadian rhythm is any biological process that displays an endogenous, entrainable oscillation of about 24 hours.
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Circulatory system
The circulatory system, also called the cardiovascular system or the vascular system, is an organ system that permits blood to circulate and transport nutrients (such as amino acids and electrolytes), oxygen, carbon dioxide, hormones, and blood cells to and from the cells in the body to provide nourishment and help in fighting diseases, stabilize temperature and pH, and maintain homeostasis.
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Cognition
Cognition is "the mental action or process of acquiring knowledge and understanding through thought, experience, and the senses".
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Conformational change
In biochemistry, a conformational change is a change in the shape of a macromolecule, often induced by environmental factors.
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Coronary circulation
Coronary circulation is the circulation of blood in the blood vessels of the heart muscle (myocardium).
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Dendrite
Dendrites (from Greek δένδρον déndron, "tree"), also dendrons, are branched protoplasmic extensions of a nerve cell that propagate the electrochemical stimulation received from other neural cells to the cell body, or soma, of the neuron from which the dendrites project.
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Diabetes mellitus
Diabetes mellitus (DM), commonly referred to as diabetes, is a group of metabolic disorders in which there are high blood sugar levels over a prolonged period.
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Dyskinesia
Dyskinesia refers to a category of movement disorders that are characterized by involuntary muscle movements, including movements similar to tics or chorea and diminished voluntary movements.
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Electrostatics
Electrostatics is a branch of physics that studies electric charges at rest.
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Endocrine system
The endocrine system is a chemical messenger system consisting of hormones, the group of glands of an organism that carry those hormones directly into the circulatory system to be carried towards distant target organs, and the feedback loops of homeostasis that the hormones drive.
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Epilepsy
Epilepsy is a group of neurological disorders characterized by epileptic seizures.
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Epileptic seizure
An epileptic seizure is a brief episode of signs or symptoms due to abnormally excessive or synchronous neuronal activity in the brain.
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Estrogen
Estrogen, or oestrogen, is the primary female sex hormone.
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Fetus
A fetus is a stage in the prenatal development of viviparous organisms.
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FMR1
FMR1 (fragile X mental retardation 1) is a human gene that codes for a protein called fragile X mental retardation protein, or FMRP.
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Fragile X syndrome
Fragile X syndrome (FXS) is a genetic disorder.
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Gaseous signaling molecules
Gaseous signaling molecules are gaseous molecules that are either synthesised internally (endogenously) in the organism, tissue or cell or are received by the organism, tissue or cell from outside (say, from the atmosphere or hydrosphere, as in the case of oxygen) and that are used to transmit chemical signals which induce certain physiological or biochemical changes in the organism, tissue or cell.
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Gene
In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.
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Glucose
Glucose is a simple sugar with the molecular formula C6H12O6.
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Glutamine
Glutamine (symbol Gln or Q) is an α-amino acid that is used in the biosynthesis of proteins.
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Goodwin & Company
Goodwin & Company was an American tobacco manufacturer from New York City.
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Hearing
Hearing, or auditory perception, is the ability to perceive sounds by detecting vibrations, changes in the pressure of the surrounding medium through time, through an organ such as the ear.
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Hypertension
Hypertension (HTN or HT), also known as high blood pressure (HBP), is a long-term medical condition in which the blood pressure in the arteries is persistently elevated.
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Hypoxia (medical)
Hypoxia is a condition in which the body or a region of the body is deprived of adequate oxygen supply at the tissue level.
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Intracellular
In cell biology, molecular biology and related fields, the word intracellular means "inside the cell".
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Ionic conductivity (solid state)
Ionic conduction (denoted by -lambda) is the movement of an ion from one site to another through defects in the crystal lattice of a solid or aqueous solution.
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Ischemia
Ischemia or ischaemia is a restriction in blood supply to tissues, causing a shortage of oxygen that is needed for cellular metabolism (to keep tissue alive).
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KCNMB1
Calcium-activated potassium channel subunit beta-1 is a protein that in humans is encoded by the KCNMB1 gene.
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KCNMB2
Calcium-activated potassium channel subunit beta-2 is a protein that in humans is encoded by the KCNMB2 gene.
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KCNMB3
Calcium-activated potassium channel subunit beta-3 is a protein that in humans is encoded by the KCNMB3 gene.
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KCNMB4
Calcium-activated potassium channel subunit beta-4 is a protein that in humans is encoded by the KCNMB4 gene.
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Kidney
The kidneys are two bean-shaped organs present in left and right sides of the body in vertebrates.
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Knockout mouse
A knockout mouse or knock-out mouse is a genetically modified mouse (Mus musculus) in which researchers have inactivated, or "knocked out", an existing gene by replacing it or disrupting it with an artificial piece of DNA.
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Ligand
In coordination chemistry, a ligand is an ion or molecule (functional group) that binds to a central metal atom to form a coordination complex.
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Ligand-gated ion channel
Ligand-gated ion channels (LICs, LGIC), also commonly referred as ionotropic receptors, are a group of transmembrane ion-channel proteins which open to allow ions such as Na+, K+, Ca2+, and/or Cl− to pass through the membrane in response to the binding of a chemical messenger (i.e. a ligand), such as a neurotransmitter.
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Magnesium
Magnesium is a chemical element with symbol Mg and atomic number 12.
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Major depressive disorder
Major depressive disorder (MDD), also known simply as depression, is a mental disorder characterized by at least two weeks of low mood that is present across most situations.
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Membrane potential
The term "membrane potential" may refer to one of three kinds of membrane potential.
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Memory
Memory is the faculty of the mind by which information is encoded, stored, and retrieved.
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Messenger RNA
Messenger RNA (mRNA) is a large family of RNA molecules that convey genetic information from DNA to the ribosome, where they specify the amino acid sequence of the protein products of gene expression.
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Methionine sulfoxide
Methionine sulfoxide is the organic compound with the formula CH3S(O)CH2CH2CH(NH2)CO2H.
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Microglia
Microglia are a type of neuroglia (glial cell) located throughout the brain and spinal cord.
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Modulation
In electronics and telecommunications, modulation is the process of varying one or more properties of a periodic waveform, called the carrier signal, with a modulating signal that typically contains information to be transmitted.
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Monomer
A monomer (mono-, "one" + -mer, "part") is a molecule that "can undergo polymerization thereby contributing constitutional units to the essential structure of a macromolecule".
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Motor coordination
Motor coordination is the combination of body movements created with the kinematic (such as spatial direction) and kinetic (force) parameters that result in intended actions.
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Mouse
A mouse (Mus), plural mice, is a small rodent characteristically having a pointed snout, small rounded ears, a body-length scaly tail and a high breeding rate.
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Mutation
In biology, a mutation is the permanent alteration of the nucleotide sequence of the genome of an organism, virus, or extrachromosomal DNA or other genetic elements.
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Neoplasm
Neoplasia is a type of abnormal and excessive growth of tissue.
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Neuron
A neuron, also known as a neurone (British spelling) and nerve cell, is an electrically excitable cell that receives, processes, and transmits information through electrical and chemical signals.
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Neurotransmission
Neurotransmission (Latin: transmissio "passage, crossing" from transmittere "send, let through"), also called synaptic transmission, is the process by which signaling molecules called neurotransmitters are released by the axon terminal of a neuron (the presynaptic neuron), and bind to and activate the receptors on the dendrites of another neuron (the postsynaptic neuron).
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Neurotransmitter
Neurotransmitters are endogenous chemicals that enable neurotransmission.
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Organ transplantation
Organ transplantation is a medical procedure in which an organ is removed from one body and placed in the body of a recipient, to replace a damaged or missing organ.
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Orphanet Journal of Rare Diseases
The Orphanet Journal of Rare Diseases is a peer-reviewed open access medical journal covering research on rare diseases.
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Overactive bladder
Overactive bladder (OAB) is a condition where there is a frequent feeling of needing to urinate to a degree that it negatively affects a person's life.
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Overexcitability
Overexcitability is a term introduced to current psychology by Kazimirz Dabrowski as part of his theory of positive disintegration (TPD).
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Oxidative stress
Oxidative stress reflects an imbalance between the systemic manifestation of reactive oxygen species and a biological system's ability to readily detoxify the reactive intermediates or to repair the resulting damage.
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Oxygen
Oxygen is a chemical element with symbol O and atomic number 8.
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Pathophysiology
Pathophysiology or physiopathology is a convergence of pathology with physiology.
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Pharmacology
Pharmacology is the branch of biology concerned with the study of drug action, where a drug can be broadly defined as any man-made, natural, or endogenous (from within body) molecule which exerts a biochemical or physiological effect on the cell, tissue, organ, or organism (sometimes the word pharmacon is used as a term to encompass these endogenous and exogenous bioactive species).
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Phosphorylation
In chemistry, phosphorylation of a molecule is the attachment of a phosphoryl group.
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Physiology
Physiology is the scientific study of normal mechanisms, and their interactions, which work within a living system.
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Placebo
A placebo is a substance or treatment of no intended therapeutic value.
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Potassium
Potassium is a chemical element with symbol K (from Neo-Latin kalium) and atomic number 19.
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Potassium channel
Potassium channels are the most widely distributed type of ion channel and are found in virtually all living organisms.
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Properties of water
Water is a polar inorganic compound that is at room temperature a tasteless and odorless liquid, which is nearly colorless apart from an inherent hint of blue. It is by far the most studied chemical compound and is described as the "universal solvent" and the "solvent of life". It is the most abundant substance on Earth and the only common substance to exist as a solid, liquid, and gas on Earth's surface. It is also the third most abundant molecule in the universe. Water molecules form hydrogen bonds with each other and are strongly polar. This polarity allows it to separate ions in salts and strongly bond to other polar substances such as alcohols and acids, thus dissolving them. Its hydrogen bonding causes its many unique properties, such as having a solid form less dense than its liquid form, a relatively high boiling point of 100 °C for its molar mass, and a high heat capacity. Water is amphoteric, meaning that it is both an acid and a base—it produces + and - ions by self-ionization.
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Protein
Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.
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Protein kinase C
Protein kinase C, commonly abbreviated to PKC (EC 2.7.11.13), is a family of protein kinase enzymes that are involved in controlling the function of other proteins through the phosphorylation of hydroxyl groups of serine and threonine amino acid residues on these proteins, or a member of this family.
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Protein phosphatase 1
Protein phosphatase 1 (PP1) belongs to a certain class of phosphatases known as protein serine/threonine phosphatases.
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Pulmonary hypertension
Pulmonary hypertension (PH or PHTN) is a condition of increased blood pressure within the arteries of the lungs.
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Purkinje cell
Purkinje cells, or Purkinje neurons, are a class of GABAergic neurons located in the cerebellum.
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Repolarization
In neuroscience, repolarization refers to the change in membrane potential that returns it to a negative value just after the depolarization phase of an action potential has changed the membrane potential to a positive value.
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Resting potential
The relatively static membrane potential of quiescent cells is called the resting membrane potential (or resting voltage), as opposed to the specific dynamic electrochemical phenomena called action potential and graded membrane potential.
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Schizophrenia
Schizophrenia is a mental disorder characterized by abnormal social behavior and failure to understand reality.
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Sensor
In the broadest definition, a sensor is a device, module, or subsystem whose purpose is to detect events or changes in its environment and send the information to other electronics, frequently a computer processor.
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Side chain
In organic chemistry and biochemistry, a side chain is a chemical group that is attached to a core part of the molecule called "main chain" or backbone.
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Smooth muscle tissue
Smooth muscle is an involuntary non-striated muscle.
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Stroke
A stroke is a medical condition in which poor blood flow to the brain results in cell death.
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Suprachiasmatic nucleus
The suprachiasmatic nucleus or nuclei (SCN) is a tiny region of the brain in the hypothalamus, situated directly above the optic chiasm.
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Synergy
Synergy is the creation of a whole that is greater than the simple sum of its parts.
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Temporal lobe
The temporal lobe is one of the four major lobes of the cerebral cortex in the brain of mammals.
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Tetrameric protein
A tetrameric protein is a protein with a quaternary structure of four subunits (tetrameric).
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Transmembrane domain
Transmembrane domain usually denotes a transmembrane segment of single alpha helix of a transmembrane protein.
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Transmembrane protein
A transmembrane protein (TP) is a type of integral membrane protein that spans the entirety of the biological membrane to which it is permanently attached.
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Uterus
The uterus (from Latin "uterus", plural uteri) or womb is a major female hormone-responsive secondary sex organ of the reproductive system in humans and most other mammals.
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Vascular resistance
Vascular resistance is the resistance that must be overcome to push blood through the circulatory system and create flow.
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Voltage-gated ion channel
Voltage-gated ion channels are a class of transmembrane proteins that form ion channels that are activated by changes in the electrical membrane potential near the channel.
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Voltage-gated potassium channel
Voltage-gated potassium channels (VGKCs) are transmembrane channels specific for potassium and sensitive to voltage changes in the cell's membrane potential.
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X-ray crystallography
X-ray crystallography is a technique used for determining the atomic and molecular structure of a crystal, in which the crystalline atoms cause a beam of incident X-rays to diffract into many specific directions.
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Redirects here:
Bk channel, Large-conductance calcium-activated potassium channel alpha subunits, Large-conductance calcium-activated potassium channel beta subunits, Large-conductance calcium-activated potassium channels, Maxi-K channel.
References
[1] https://en.wikipedia.org/wiki/BK_channel
