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18 relations: Alan Fersht, Amino acid, Bacillus amyloliquefaciens, Barstar, Biomolecular structure, Dissociation constant, Disulfide, Hydrolysis, Phi value analysis, Portmanteau, Protein, Protein folding, Protein–protein interaction, Ribonuclease, RNA, Toxin-antitoxin system, Transesterification, Transition state.
Alan Fersht
Sir Alan Roy Fersht, FRS, FMedSci (born 21 April 1943) is a British chemist at the Laboratory of Molecular Biology and an Emeritus Professor in the Department of Chemistry at the University of Cambridge.
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Amino acid
Amino acids are organic compounds containing amine (-NH2) and carboxyl (-COOH) functional groups, along with a side chain (R group) specific to each amino acid.
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Bacillus amyloliquefaciens
Bacillus amyloliquefaciens is a species of bacterium in the genus Bacillus that is the source of the BamH1 restriction enzyme.
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Barstar
Barstar is a small protein synthesized by the bacterium Bacillus amyloliquefaciens.
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Biomolecular structure
Biomolecular structure is the intricate folded, three-dimensional shape that is formed by a molecule of protein, DNA, or RNA, and that is important to its function.
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Dissociation constant
In chemistry, biochemistry, and pharmacology, a dissociation constant (K_d) is a specific type of equilibrium constant that measures the propensity of a larger object to separate (dissociate) reversibly into smaller components, as when a complex falls apart into its component molecules, or when a salt splits up into its component ions.
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Disulfide
In chemistry, a disulfide refers to a functional group with the structure R−S−S−R′.
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Hydrolysis
Hydrolysis is a term used for both an electro-chemical process and a biological one.
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Phi value analysis
Phi value analysis, \phi analysis, or \phi-value analysis is an experimental protein engineering technique for studying the structure of the folding transition state of small protein domains that fold in a two-state manner.
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Portmanteau
A portmanteau or portmanteau word is a linguistic blend of words,, p. 644 in which parts of multiple words or their phones (sounds) are combined into a new word, as in smog, coined by blending smoke and fog, or motel, from motor and hotel.
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Protein
Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.
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Protein folding
Protein folding is the physical process by which a protein chain acquires its native 3-dimensional structure, a conformation that is usually biologically functional, in an expeditious and reproducible manner.
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Protein–protein interaction
Protein–protein interactions (PPIs) are the physical contacts of high specificity established between two or more protein molecules as a result of biochemical events steered by electrostatic forces including the hydrophobic effect.
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Ribonuclease
Ribonuclease (commonly abbreviated RNase) is a type of nuclease that catalyzes the degradation of RNA into smaller components.
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RNA
Ribonucleic acid (RNA) is a polymeric molecule essential in various biological roles in coding, decoding, regulation, and expression of genes.
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Toxin-antitoxin system
A toxin-antitoxin system is a set of two or more closely linked genes that together encode both a protein 'poison' and a corresponding 'antidote'.
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Transesterification
In organic chemistry, transesterfication is the process of exchanging the organic group R″ of an ester with the organic group R′ of an alcohol.
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Transition state
The transition state of a chemical reaction is a particular configuration along the reaction coordinate.
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