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Bcl-xL

Index Bcl-xL

B-cell lymphoma-extra large (Bcl-xL), encoded by the BCL2-like 1 gene, is a transmembrane molecule in the mitochondria. [1]

16 relations: Apoptosis, Bcl-2, Bcl-2 family, Bcl-2 homologous antagonist killer, Bcl-2-associated X protein, BCL2-like 1 (gene), BCL2L11, BCL2L2, Caspase, Cytochrome c, Doxorubicin, GATA1, MCL1, Mitochondrion, P53, Polycythemia vera.

Apoptosis

Apoptosis (from Ancient Greek ἀπόπτωσις "falling off") is a process of programmed cell death that occurs in multicellular organisms.

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Bcl-2

Bcl-2 (B-cell lymphoma 2), encoded in humans by the BCL2 gene, is the founding member of the Bcl-2 family of regulator proteins that regulate cell death (apoptosis), by either inducing (pro-apoptotic) or inhibiting (anti-apoptotic) apoptosis.

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Bcl-2 family

The Bcl-2 Family consists of a number of evolutionarily-conserved proteins that share Bcl-2 homology (BH) domains.

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Bcl-2 homologous antagonist killer

Bcl-2 homologous antagonist/killer is a protein that in humans is encoded by the BAK1 gene on chromosome 6.

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Bcl-2-associated X protein

Apoptosis regulator BAX, also known as bcl-2-like protein 4, is a protein that in humans is encoded by the BAX gene.

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BCL2-like 1 (gene)

Bcl-2-like 1 or BCL2L1 is a human gene.

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BCL2L11

Bcl-2-like protein 11, commonly called BIM, is a protein that in humans is encoded by the BCL2L11 gene.

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BCL2L2

Bcl-2-like protein 2 is a protein that in humans is encoded by the BCL2L2 gene.

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Caspase

Caspases (cysteine-aspartic proteases, cysteine aspartases or cysteine-dependent aspartate-directed proteases) are a family of protease enzymes playing essential roles in programmed cell death (including apoptosis, pyroptosis and necroptosis) and inflammation.

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Cytochrome c

The cytochrome complex, or cyt c is a small hemeprotein found loosely associated with the inner membrane of the mitochondrion.

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Doxorubicin

Doxorubicin, sold under the trade names Adriamycin among others, is a chemotherapy medication used to treat cancer.

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GATA1

GATA-binding factor 1 or GATA-1 (also termed Erythroid transcription factor) is the founding member of the GATA family of transcription factors.

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MCL1

Induced myeloid leukemia cell differentiation protein Mcl-1 is a protein that in humans is encoded by the MCL1 gene.

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Mitochondrion

The mitochondrion (plural mitochondria) is a double-membrane-bound organelle found in most eukaryotic organisms.

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P53

Tumor protein p53, also known as p53, cellular tumor antigen p53 (UniProt name), phosphoprotein p53, tumor suppressor p53, antigen NY-CO-13, or transformation-related protein 53 (TRP53), is any isoform of a protein encoded by homologous genes in various organisms, such as TP53 (humans) and Trp53 (mice).

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Polycythemia vera

Polycythemia vera is an uncommon neoplasm in which the bone marrow makes too many red blood cells.

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Redirects here:

Bcl-Xl, Bcl-xl.

References

[1] https://en.wikipedia.org/wiki/Bcl-xL

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