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Binding immunoglobulin protein

Index Binding immunoglobulin protein

Binding immunoglobulin protein (BiP) also known as 78 kDa glucose-regulated protein (GRP-78) or heat shock 70 kDa protein 5 (HSPA5) is a protein that in humans is encoded by the HSPA5 gene. [1]

76 relations: AB5 toxin, Adenosine triphosphate, Adipogenesis, Adipose tissue, Allosteric enzyme, Alpha factor, Alzheimer's disease, Antibiotic, Antimicrobial resistance, ATF6, Atherosclerosis, ATPase, Blood vessel, Chaperone (protein), Chaperone DnaJ, Chemotherapy, Cholesterol, Co-chaperone, Coagulation, Collagen-induced arthritis, Dendritic cell, Diabetes mellitus type 2, Dilated cardiomyopathy, Disulfide, DNA replication, EIF2AK3, Endoplasmic reticulum, Endoplasmic-reticulum-associated protein degradation, Endothelium, ERN1, Foldase, Gene, Gene (journal), Glucose, Glucose-regulated protein, Glutathione, Glycosylation, GPX7, Holdase, Homocysteine, Homology (biology), Hsp70, Infant, Inflammation, Invertase, Ischemia, Lumen (anatomy), Monocyte, Neisseria gonorrhoeae, Nucleotide exchange factor, ..., Obesity, Oligomer, Pancreatitis, Peptide, Post-translational modification, Prokaryote, Proteasome, Proteasome inhibitor, Protein, Protein aggregation, Protein disulfide-isomerase, Protein domain, Protein folding, Protein targeting, RecA, Secretory protein, Shigatoxigenic and verotoxigenic Escherichia coli, Strain (biology), Sulfenic acid, T cell, Temperature-sensitive mutant, Triglyceride, Unfolded protein response, Virulence, Virus, Zygosity. Expand index (26 more) »

AB5 toxin

The AB5 toxins are six-component protein complexes secreted by certain pathogenic bacteria known to cause human diseases such as cholera, dysentery, and hemolytic-uremic syndrome.

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Adenosine triphosphate

Adenosine triphosphate (ATP) is a complex organic chemical that participates in many processes.

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Adipogenesis

Adipogenesis is the process of cell differentiation by which pre-adipocytes become adipocytes.

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Adipose tissue

In biology, adipose tissue, body fat, or simply fat is a loose connective tissue composed mostly of adipocytes.

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Allosteric enzyme

Allosteric enzymes are enzymes that change their conformational ensemble upon binding of an effector, which results in an apparent change in binding affinity at a different ligand binding site.

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Alpha factor

The α-factor is used to predict the solid–liquid interface type of a material during solidification.

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Alzheimer's disease

Alzheimer's disease (AD), also referred to simply as Alzheimer's, is a chronic neurodegenerative disease that usually starts slowly and worsens over time.

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Antibiotic

An antibiotic (from ancient Greek αντιβιοτικά, antibiotiká), also called an antibacterial, is a type of antimicrobial drug used in the treatment and prevention of bacterial infections.

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Antimicrobial resistance

Antimicrobial resistance (AMR or AR) is the ability of a microbe to resist the effects of medication that once could successfully treat the microbe.

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ATF6

Activating transcription factor 6, also known as ATF6, is a protein that, in humans, is encoded by the ATF6 gene and is involved in the unfolded protein response.

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Atherosclerosis

Atherosclerosis is a disease in which the inside of an artery narrows due to the build up of plaque.

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ATPase

ATPases (adenylpyrophosphatase, ATP monophosphatase, triphosphatase, SV40 T-antigen, adenosine 5'-triphosphatase, ATP hydrolase, complex V (mitochondrial electron transport), (Ca2+ + Mg2+)-ATPase, HCO3−-ATPase, adenosine triphosphatase) are a class of enzymes that catalyze the decomposition of ATP into ADP and a free phosphate ion.

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Blood vessel

The blood vessels are the part of the circulatory system, and microcirculation, that transports blood throughout the human body.

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Chaperone (protein)

In molecular biology, molecular chaperones are proteins that assist the covalent folding or unfolding and the assembly or disassembly of other macromolecular structures.

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Chaperone DnaJ

In molecular biology, chaperone DnaJ, also known as Hsp40 (heat shock protein 40 kD), is a molecular chaperone protein.

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Chemotherapy

Chemotherapy (often abbreviated to chemo and sometimes CTX or CTx) is a type of cancer treatment that uses one or more anti-cancer drugs (chemotherapeutic agents) as part of a standardized chemotherapy regimen.

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Cholesterol

Cholesterol (from the Ancient Greek chole- (bile) and stereos (solid), followed by the chemical suffix -ol for an alcohol) is an organic molecule.

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Co-chaperone

Co-chaperones are proteins that assist chaperones in protein folding and other functions.

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Coagulation

Coagulation (also known as clotting) is the process by which blood changes from a liquid to a gel, forming a blood clot.

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Collagen-induced arthritis

Collagen-induced arthritis (CIA) is a condition induced in mice (or rats) to study rheumatoid arthritis.

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Dendritic cell

Dendritic cells (DCs) are antigen-presenting cells (also known as accessory cells) of the mammalian immune system.

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Diabetes mellitus type 2

Diabetes mellitus type 2 (also known as type 2 diabetes) is a long-term metabolic disorder that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.

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Dilated cardiomyopathy

Dilated cardiomyopathy (DCM) is a condition in which the heart becomes enlarged and cannot pump blood effectively.

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Disulfide

In chemistry, a disulfide refers to a functional group with the structure R−S−S−R′.

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DNA replication

In molecular biology, DNA replication is the biological process of producing two identical replicas of DNA from one original DNA molecule.

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EIF2AK3

Eukaryotic translation initiation factor 2-alpha kinase 3, also known as protein kinase R (PKR)-like endoplasmic reticulum kinase (PERK), is an enzyme that in humans is encoded by the EIF2AK3 gene.

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Endoplasmic reticulum

The endoplasmic reticulum (ER) is a type of organelle found in eukaryotic cells that forms an interconnected network of flattened, membrane-enclosed sacs or tube-like structures known as cisternae.

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Endoplasmic-reticulum-associated protein degradation

Endoplasmic-reticulum-associated protein degradation (ERAD) designates a cellular pathway which targets misfolded proteins of the endoplasmic reticulum for ubiquitination and subsequent degradation by a protein-degrading complex, called the proteasome.

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Endothelium

Endothelium refers to cells that line the interior surface of blood vessels and lymphatic vessels, forming an interface between circulating blood or lymph in the lumen and the rest of the vessel wall.

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ERN1

The serine/threonine-protein kinase/endoribonuclease inositol-requiring enzyme 1 (IRE1) is an enzyme that in humans is encoded by the ERN1 gene.

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Foldase

In molecular biology, foldases are a particular kind of molecular chaperones that assist the non-covalent folding of proteins in an ATP-dependent manner.

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Gene

In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.

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Gene (journal)

Gene is a peer-reviewed scientific journal in genetics, focusing on the cloning, structure, and function of genes.

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Glucose

Glucose is a simple sugar with the molecular formula C6H12O6.

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Glucose-regulated protein

Glucose-regulated protein is a protein in the endoplasmic reticulum in the cell.

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Glutathione

Glutathione (GSH) is an important antioxidant in plants, animals, fungi, and some bacteria and archaea.

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Glycosylation

Glycosylation (see also chemical glycosylation) is the reaction in which a carbohydrate, i.e. a glycosyl donor, is attached to a hydroxyl or other functional group of another molecule (a glycosyl acceptor).

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GPX7

Glutathione peroxidase 7 is an enzyme that in humans is encoded by the GPX7 gene.

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Holdase

In molecular biology, holdases are a particular kind of molecular chaperones that assist the non-covalent folding of proteins in an ATP-independent manner.

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Homocysteine

Homocysteine is a non-proteinogenic α-amino acid.

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Homology (biology)

In biology, homology is the existence of shared ancestry between a pair of structures, or genes, in different taxa.

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Hsp70

The 70 kilodalton heat shock proteins (Hsp70s or DnaK) are a family of conserved ubiquitously expressed heat shock proteins.

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Infant

An infant (from the Latin word infans, meaning "unable to speak" or "speechless") is the more formal or specialised synonym for "baby", the very young offspring of a human.

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Inflammation

Inflammation (from inflammatio) is part of the complex biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or irritants, and is a protective response involving immune cells, blood vessels, and molecular mediators.

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Invertase

Invertase is an enzyme that catalyzes the hydrolysis (breakdown) of sucrose (table sugar) into fructose and glucose.

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Ischemia

Ischemia or ischaemia is a restriction in blood supply to tissues, causing a shortage of oxygen that is needed for cellular metabolism (to keep tissue alive).

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Lumen (anatomy)

In biology, a lumen (plural lumina) is the inside space of a tubular structure, such as an artery or intestine.

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Monocyte

Monocytes are a type of leukocyte, or white blood cell.

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Neisseria gonorrhoeae

Neisseria gonorrhoeae, also known as gonococcus (singular), or gonococci (plural) is a species of gram-negative diplococci bacteria isolated by Albert Neisser in 1879.

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Nucleotide exchange factor

Nucleotide exchange factors (NEFs) are proteins that stimulate the exchange (replacement) of nucleoside diphosphates for nucleoside triphosphates bound to other proteins.

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Obesity

Obesity is a medical condition in which excess body fat has accumulated to the extent that it may have a negative effect on health.

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Oligomer

An oligomer (oligo-, "a few" + -mer, "parts") is a molecular complex of chemicals that consists of a few monomer units, in contrast to a polymer, where the number of monomers is, in principle, infinite.

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Pancreatitis

Pancreatitis is inflammation of the pancreas.

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Peptide

Peptides (from Gr.: πεπτός, peptós "digested"; derived from πέσσειν, péssein "to digest") are short chains of amino acid monomers linked by peptide (amide) bonds.

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Post-translational modification

Post-translational modification (PTM) refers to the covalent and generally enzymatic modification of proteins following protein biosynthesis.

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Prokaryote

A prokaryote is a unicellular organism that lacks a membrane-bound nucleus, mitochondria, or any other membrane-bound organelle.

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Proteasome

Proteasomes are protein complexes which degrade unneeded or damaged proteins by proteolysis, a chemical reaction that breaks peptide bonds.

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Proteasome inhibitor

Proteasome inhibitors are drugs that block the action of proteasomes, cellular complexes that break down proteins.

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Protein

Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.

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Protein aggregation

Protein aggregation is a biological phenomenon in which mis-folded proteins aggregate (i.e., accumulate and clump together) either intra- or extracellularly.

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Protein disulfide-isomerase

Protein disulfide isomerase, or PDI, is an enzyme in the endoplasmic reticulum (ER) in eukaryotes and the periplasm of bacteria that catalyzes the formation and breakage of disulfide bonds between cysteine residues within proteins as they fold.

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Protein domain

A protein domain is a conserved part of a given protein sequence and (tertiary) structure that can evolve, function, and exist independently of the rest of the protein chain.

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Protein folding

Protein folding is the physical process by which a protein chain acquires its native 3-dimensional structure, a conformation that is usually biologically functional, in an expeditious and reproducible manner.

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Protein targeting

Protein targeting or protein sorting is the biological mechanism by which proteins are transported to the appropriate destinations in the cell or outside it.

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RecA

RecA is a 38 kilodalton protein essential for the repair and maintenance of DNA.

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Secretory protein

A secretory protein is any protein, whether it be endocrine or exocrine, which is secreted by a cell.

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Shigatoxigenic and verotoxigenic Escherichia coli

Shigatoxigenic Escherichia coli (STEC) and verotoxigenic E. coli (VTEC) are strains of the bacterium Escherichia coli that produce either Shiga toxin or Shiga-like toxin (verotoxin).

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Strain (biology)

In biology, a strain is a low-level taxonomic rank used at the intraspecific level (within a species).

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Sulfenic acid

A sulfenic acid is an organosulfur compound and oxoacid with the general formula RSOH.

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T cell

A T cell, or T lymphocyte, is a type of lymphocyte (a subtype of white blood cell) that plays a central role in cell-mediated immunity.

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Temperature-sensitive mutant

Temperature sensitive mutants are variants of genes that allow normal function of the organism at low temperatures, but altered function at higher temperatures.

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Triglyceride

A triglyceride (TG, triacylglycerol, TAG, or triacylglyceride) is an ester derived from glycerol and three fatty acids (from tri- and glyceride).

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Unfolded protein response

The unfolded protein response (UPR) is a cellular stress response related to the endoplasmic reticulum (ER) stress.

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Virulence

Virulence is a pathogen's or microbe's ability to infect or damage a host.

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Virus

A virus is a small infectious agent that replicates only inside the living cells of other organisms.

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Zygosity

Zygosity is the degree of similarity of the alleles for a trait in an organism.

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Redirects here:

BiP protein, Glucose regulate protein 78, Grp78, HSPA5, HSPA5 (gene), Heat shock 70kDa protein 5.

References

[1] https://en.wikipedia.org/wiki/Binding_immunoglobulin_protein

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