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Binding selectivity

Index Binding selectivity

Binding selectivity is defined with respect to the binding of ligands to a substrate forming a complex. [1]

63 relations: Absorbance, Agonist, Analyte, Antagonist, Antibiotic, Biochemistry, Blood transfusion, Calcium, Cascade (chemical engineering), Cell membrane, Chelation, Cimetidine, Concentration, Coordination complex, Copper, Countercurrent exchange, Cytoplasm, Deferasirox, Deferiprone, Deferoxamine, Equilibrium constant, Ethylenediaminetetraacetic acid, Functional selectivity, Gas chromatography, H2 antagonist, Hormone, Hydrogen bond, Ion selective electrode, Iron overload, Kerosene, Lanthanide, Lead, Ligand (biochemistry), Luminescence, Magnesium, Mercury (element), Molecular binding, Monazite, Neurotransmitter, Non-covalent interactions, Oxidation state, Partition coefficient, Penicillamine, Peptic ulcer disease, Peptide, Periodic table, Potassium, Protein, Quantitative structure–activity relationship, Ranitidine, ..., Retardation factor, Separation process, Siderophore, Stability constants of complexes, Stoichiometry, Streptomyces pilosus, Thalassemia, Theoretical plate, Thermodynamic activity, Tributyl phosphate, Valinomycin, Van der Waals force, Wilson's disease. Expand index (13 more) »

Absorbance

In chemistry, absorbance or decadic absorbance is the common logarithm of the ratio of incident to transmitted radiant power through a material, and spectral absorbance or spectral decadic absorbance is the common logarithm of the ratio of incident to transmitted spectral radiant power through a material.

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Agonist

An agonist is a chemical that binds to a receptor and activates the receptor to produce a biological response.

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Analyte

An analyte, component (in clinical chemistry), or chemical species is a substance or chemical constituent that is of interest in an analytical procedure.

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Antagonist

An antagonist is a character, group of characters, institution or concept that stands in or represents opposition against which the protagonist(s) must contend.

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Antibiotic

An antibiotic (from ancient Greek αντιβιοτικά, antibiotiká), also called an antibacterial, is a type of antimicrobial drug used in the treatment and prevention of bacterial infections.

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Biochemistry

Biochemistry, sometimes called biological chemistry, is the study of chemical processes within and relating to living organisms.

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Blood transfusion

Blood transfusion is generally the process of receiving blood or blood products into one's circulation intravenously.

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Calcium

Calcium is a chemical element with symbol Ca and atomic number 20.

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Cascade (chemical engineering)

In chemical engineering, a cascade is a plant consisting of several similar stages with each processing the output from the previous stage.

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Cell membrane

The cell membrane (also known as the plasma membrane or cytoplasmic membrane, and historically referred to as the plasmalemma) is a biological membrane that separates the interior of all cells from the outside environment (the extracellular space).

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Chelation

Chelation is a type of bonding of ions and molecules to metal ions.

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Cimetidine

Cimetidine, sold under the brand name Tagamet among others, is a histamine H2 receptor antagonist that inhibits stomach acid production.

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Concentration

In chemistry, concentration is the abundance of a constituent divided by the total volume of a mixture.

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Coordination complex

In chemistry, a coordination complex consists of a central atom or ion, which is usually metallic and is called the coordination centre, and a surrounding array of bound molecules or ions, that are in turn known as ligands or complexing agents.

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Copper

Copper is a chemical element with symbol Cu (from cuprum) and atomic number 29.

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Countercurrent exchange

Countercurrent exchange is a mechanism occurring in nature and mimicked in industry and engineering, in which there is a crossover of some property, usually heat or some component, between two flowing bodies flowing in opposite directions to each other.

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Cytoplasm

In cell biology, the cytoplasm is the material within a living cell, excluding the cell nucleus.

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Deferasirox

Deferasirox (marketed as Exjade, Desirox, Defrijet, Desifer, Rasiroxpine and Jadenu) is an oral iron chelator.

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Deferiprone

Deferiprone (tradenames include Ferriprox) is a drug that chelates iron and is used to treat iron overload in thalassaemia major.

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Deferoxamine

Deferoxamine (DFOA), sold under the brand name Desferal, is a medication that binds iron and aluminium.

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Equilibrium constant

The equilibrium constant of a chemical reaction is the value of its reaction quotient at chemical equilibrium, a state approached by a dynamic chemical system after sufficient time has elapsed at which its composition has no measurable tendency towards further change.

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Ethylenediaminetetraacetic acid

Ethylenediaminetetraacetic acid (EDTA), also known by several other names, is a chemical originating in multiseasonal plants with dormancy stages as a lipidopreservative which helps to develop the stem, currently used for both industrial and medical purposes.

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Functional selectivity

Functional selectivity (or “agonist trafficking”, “biased agonism”, “biased signalling”, "ligand bias" and “differential engagement”) is the ligand-dependent selectivity for certain signal transduction pathways relative to a reference ligand (often the endogenous hormone or peptide) at the same receptor.

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Gas chromatography

Gas chromatography (GC) is a common type of chromatography used in analytical chemistry for separating and analyzing compounds that can be vaporized without decomposition.

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H2 antagonist

H2 antagonists, sometimes referred to as H2RA and also called H2 blockers, are a class of medications that block the action of histamine at the histamine H2 receptors of the parietal cells in the stomach.

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Hormone

A hormone (from the Greek participle “ὁρμῶ”, "to set in motion, urge on") is any member of a class of signaling molecules produced by glands in multicellular organisms that are transported by the circulatory system to target distant organs to regulate physiology and behaviour.

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Hydrogen bond

A hydrogen bond is a partially electrostatic attraction between a hydrogen (H) which is bound to a more electronegative atom such as nitrogen (N), oxygen (O), or fluorine (F), and another adjacent atom bearing a lone pair of electrons.

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Ion selective electrode

An ion-selective electrode (ISE), also known as a specific ion electrode (SIE), is a transducer (or sensor) that converts the activity of a specific ion dissolved in a solution into an electrical potential.

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Iron overload

Iron overload (variously known as haemochromatosis, hemochromatosis, hemochromocytosis, Celtic curse, Irish illness, British gene, Scottish sickness and bronzing diabetes) indicates accumulation of iron in the body from any cause.

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Kerosene

Kerosene, also known as paraffin, lamp oil, and coal oil (an obsolete term), is a combustible hydrocarbon liquid which is derived from petroleum.

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Lanthanide

The lanthanide or lanthanoid series of chemical elements comprises the 15 metallic chemical elements with atomic numbers 57 through 71, from lanthanum through lutetium.

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Lead

Lead is a chemical element with symbol Pb (from the Latin plumbum) and atomic number 82.

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Ligand (biochemistry)

In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose.

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Luminescence

Luminescence is emission of light by a substance not resulting from heat; it is thus a form of cold-body radiation.

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Magnesium

Magnesium is a chemical element with symbol Mg and atomic number 12.

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Mercury (element)

Mercury is a chemical element with symbol Hg and atomic number 80.

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Molecular binding

Molecular binding is an attractive interaction between two molecules that results in a stable association in which the molecules are in close proximity to each other.

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Monazite

Monazite is a reddish-brown phosphate mineral containing rare-earth metals.

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Neurotransmitter

Neurotransmitters are endogenous chemicals that enable neurotransmission.

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Non-covalent interactions

A non-covalent interaction differs from a covalent bond in that it does not involve the sharing of electrons, but rather involves more dispersed variations of electromagnetic interactions between molecules or within a molecule.

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Oxidation state

The oxidation state, sometimes referred to as oxidation number, describes degree of oxidation (loss of electrons) of an atom in a chemical compound.

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Partition coefficient

In the physical sciences, a partition-coefficient (P) or distribution-coefficient (D) is the ratio of concentrations of a compound in a mixture of two immiscible phases at equilibrium.

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Penicillamine

Penicillamine, sold under the trade names of Cuprimine among others, is a medication primarily used for the treatment of Wilson's disease.

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Peptic ulcer disease

Peptic ulcer disease (PUD) is a break in the lining of the stomach, first part of the small intestine or occasionally the lower esophagus.

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Peptide

Peptides (from Gr.: πεπτός, peptós "digested"; derived from πέσσειν, péssein "to digest") are short chains of amino acid monomers linked by peptide (amide) bonds.

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Periodic table

The periodic table is a tabular arrangement of the chemical elements, ordered by their atomic number, electron configuration, and recurring chemical properties, whose structure shows periodic trends.

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Potassium

Potassium is a chemical element with symbol K (from Neo-Latin kalium) and atomic number 19.

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Protein

Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.

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Quantitative structure–activity relationship

Quantitative structure–activity relationship models (QSAR models) are regression or classification models used in the chemical and biological sciences and engineering.

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Ranitidine

Ranitidine, sold under the trade name Zantac among others, is a medication which decreases stomach acid production.

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Retardation factor

In chromatography, the retardation factor (R) is the fraction of an analyte in the mobile phase of a chromatographic system.

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Separation process

A separation process is a method that converts a mixture or solution of chemical substances into two or more distinct product mixtures.

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Siderophore

Siderophores (Greek: "iron carrier") are small, high-affinity iron-chelating compounds secreted by microorganisms such as bacteria and fungi and serving to transport iron across cell membranes.

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Stability constants of complexes

A stability constant (formation constant, binding constant) is an equilibrium constant for the formation of a complex in solution.

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Stoichiometry

Stoichiometry is the calculation of reactants and products in chemical reactions.

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Streptomyces pilosus

Streptomyces pilosus is a bacterium species from the genus of Streptomyces which has been isolated from soil in Rome in Italy.

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Thalassemia

Thalassemias are inherited blood disorders characterized by abnormal hemoglobin production.

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Theoretical plate

A theoretical plate in many separation processes is a hypothetical zone or stage in which two phases, such as the liquid and vapor phases of a substance, establish an equilibrium with each other.

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Thermodynamic activity

In chemical thermodynamics, activity (symbol) is a measure of the "effective concentration" of a species in a mixture, in the sense that the species' chemical potential depends on the activity of a real solution in the same way that it would depend on concentration for an ideal solution.

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Tributyl phosphate

Tributyl phosphate, known commonly as TBP, is an organophosphorus compound with the chemical formula (CH3CH2CH2CH2O)3PO.

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Valinomycin

Valinomycin is a naturally occurring dodecadepsipeptide used in the transport of potassium and as an antibiotic.

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Van der Waals force

In molecular physics, the van der Waals forces, named after Dutch scientist Johannes Diderik van der Waals, are distance-dependent interactions between atoms or molecules.

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Wilson's disease

Wilson's disease is a genetic disorder in which copper builds up in the body.

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Redirects here:

Protein selectivity, Receptor selectivity, Selectivity (pharmacology).

References

[1] https://en.wikipedia.org/wiki/Binding_selectivity

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