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Bioconjugation

Index Bioconjugation

Bioconjugation is a chemical strategy to form a stable covalent link between two molecules, at least one of which is a biomolecule. [1]

Table of Contents

  1. 131 relations: Acid, Acid dissociation constant, Acylation, Aldehyde, Alkyne, Amide, Amine, Ammonium, Aniline, Antibody–drug conjugate, Aqueous solution, Aromaticity, Aspartic acid, Azide, Azide-alkyne Huisgen cycloaddition, Azo coupling, Benzoyl group, Bioconjugate Chemistry, Biodistribution, Biomarker, Biomolecular engineering, Biomolecule, Bioorthogonal chemistry, Biotin, Biotinylation, Brentuximab vedotin, C-terminus, Carbon nanotube, Carbonyl group, Carolyn Bertozzi, Cell membrane, Chemical synthesis, Chemoselectivity, Click chemistry, Condensation reaction, Covalent bond, Cross-coupling reaction, Cyclooctyne, Cysteine, Dehydration reaction, Deprotonation, Dialkylbiaryl phosphine ligands, Diazonium compound, Disulfide, Electron-withdrawing group, Electrophile, Electrophilic aromatic substitution, Enzyme, Ester, Exogeny, ... Expand index (81 more) »

Acid

An acid is a molecule or ion capable of either donating a proton (i.e. hydrogen ion, H+), known as a Brønsted–Lowry acid, or forming a covalent bond with an electron pair, known as a Lewis acid.

See Bioconjugation and Acid

Acid dissociation constant

In chemistry, an acid dissociation constant (also known as acidity constant, or acid-ionization constant; denoted) is a quantitative measure of the strength of an acid in solution.

See Bioconjugation and Acid dissociation constant

Acylation

In chemistry, acylation is a broad class of chemical reactions in which an acyl group is added to a substrate.

See Bioconjugation and Acylation

Aldehyde

In organic chemistry, an aldehyde is an organic compound containing a functional group with the structure.

See Bioconjugation and Aldehyde

Alkyne

\ce \ce Acetylene \ce \ce \ce Propyne \ce \ce \ce \ce 1-Butyne In organic chemistry, an alkyne is an unsaturated hydrocarbon containing at least one carbon—carbon triple bond.

See Bioconjugation and Alkyne

Amide

In organic chemistry, an amide, also known as an organic amide or a carboxamide, is a compound with the general formula, where R, R', and R″ represent any group, typically organyl groups or hydrogen atoms.

See Bioconjugation and Amide

Amine

In chemistry, amines are compounds and functional groups that contain a basic nitrogen atom with a lone pair.

See Bioconjugation and Amine

Ammonium

Ammonium is a modified form of ammonia that has an extra hydrogen atom.

See Bioconjugation and Ammonium

Aniline

Aniline (and -ine indicating a derived substance) is an organic compound with the formula.

See Bioconjugation and Aniline

Antibody–drug conjugate

Antibody–drug conjugates or ADCs are a class of biopharmaceutical drugs designed as a targeted therapy for treating cancer.

See Bioconjugation and Antibody–drug conjugate

Aqueous solution

An aqueous solution is a solution in which the solvent is water.

See Bioconjugation and Aqueous solution

Aromaticity

In organic chemistry, aromaticity is a chemical property describing the way in which a conjugated ring of unsaturated bonds, lone pairs, or empty orbitals exhibits a stabilization stronger than would be expected by the stabilization of conjugation alone.

See Bioconjugation and Aromaticity

Aspartic acid

Aspartic acid (symbol Asp or D; the ionic form is known as aspartate), is an α-amino acid that is used in the biosynthesis of proteins.

See Bioconjugation and Aspartic acid

Azide

In chemistry, azide is a linear, polyatomic anion with the formula and structure.

See Bioconjugation and Azide

Azide-alkyne Huisgen cycloaddition

The azide-alkyne Huisgen cycloaddition is a 1,3-dipolar cycloaddition between an azide and a terminal or internal alkyne to give a 1,2,3-triazole.

See Bioconjugation and Azide-alkyne Huisgen cycloaddition

Azo coupling

In organic chemistry, an azo coupling is an reaction between a diazonium compound and another aromatic compound that produces an azo compound.

See Bioconjugation and Azo coupling

Benzoyl group

In organic chemistry, benzoyl is the functional group with the formula and structure.

See Bioconjugation and Benzoyl group

Bioconjugate Chemistry

Bioconjugate Chemistry is a monthly peer-reviewed scientific journal covering research in bioconjugation and the interface between man-made and biological materials.

See Bioconjugation and Bioconjugate Chemistry

Biodistribution

Biodistribution is a method of tracking where compounds of interest travel in an experimental animal or human subject.

See Bioconjugation and Biodistribution

Biomarker

In biomedical contexts, a biomarker, or biological marker, is a measurable indicator of some biological state or condition.

See Bioconjugation and Biomarker

Biomolecular engineering

Biomolecular engineering is the application of engineering principles and practices to the purposeful manipulation of molecules of biological origin.

See Bioconjugation and Biomolecular engineering

Biomolecule

A biomolecule or biological molecule is loosely defined as a molecule produced by a living organism and essential to one or more typically biological processes. Bioconjugation and biomolecule are biochemistry.

See Bioconjugation and Biomolecule

Bioorthogonal chemistry

The term bioorthogonal chemistry refers to any chemical reaction that can occur inside of living systems without interfering with native biochemical processes.

See Bioconjugation and Bioorthogonal chemistry

Biotin

Biotin (also known as vitamin B7 or vitamin H) is one of the B vitamins.

See Bioconjugation and Biotin

Biotinylation

In biochemistry, biotinylation is the process of covalently attaching biotin to a protein, nucleic acid or other molecule.

See Bioconjugation and Biotinylation

Brentuximab vedotin

Brentuximab vedotin, sold under the brand name Adcetris, is an antibody-drug conjugate medication used to treat relapsed or refractory Hodgkin lymphoma (HL) and systemic anaplastic large cell lymphoma (ALCL), a type of T cell non-Hodgkin lymphoma.

See Bioconjugation and Brentuximab vedotin

C-terminus

The C-terminus (also known as the carboxyl-terminus, carboxy-terminus, C-terminal tail, carboxy tail, C-terminal end, or COOH-terminus) is the end of an amino acid chain (protein or polypeptide), terminated by a free carboxyl group (-COOH).

See Bioconjugation and C-terminus

Carbon nanotube

A scanning tunneling microscopy image of a single-walled carbon nanotube Rotating single-walled zigzag carbon nanotube A carbon nanotube (CNT) is a tube made of carbon with a diameter in the nanometre range (nanoscale).

See Bioconjugation and Carbon nanotube

Carbonyl group

For organic chemistry, a carbonyl group is a functional group with the formula, composed of a carbon atom double-bonded to an oxygen atom, and it is divalent at the C atom.

See Bioconjugation and Carbonyl group

Carolyn Bertozzi

Carolyn Ruth Bertozzi (born October 10, 1966) is an American chemist and Nobel laureate, known for her wide-ranging work spanning both chemistry and biology.

See Bioconjugation and Carolyn Bertozzi

Cell membrane

The cell membrane (also known as the plasma membrane or cytoplasmic membrane, and historically referred to as the plasmalemma) is a biological membrane that separates and protects the interior of a cell from the outside environment (the extracellular space).

See Bioconjugation and Cell membrane

Chemical synthesis

Chemical synthesis (chemical combination) is the artificial execution of chemical reactions to obtain one or several products.

See Bioconjugation and Chemical synthesis

Chemoselectivity

Chemoselectivity is the preferential reaction of a chemical reagent with one of two or more different functional groups.

See Bioconjugation and Chemoselectivity

Click chemistry

In chemical synthesis, click chemistry is a class of simple, atom-economy reactions commonly used for joining two molecular entities of choice.

See Bioconjugation and Click chemistry

Condensation reaction

In organic chemistry, a condensation reaction is a type of chemical reaction in which two molecules are combined to form a single molecule, usually with the loss of a small molecule such as water.

See Bioconjugation and Condensation reaction

Covalent bond

A covalent bond is a chemical bond that involves the sharing of electrons to form electron pairs between atoms. Bioconjugation and covalent bond are chemical bonding.

See Bioconjugation and Covalent bond

Cross-coupling reaction

In organic chemistry, a cross-coupling reaction is a reaction where two different fragments are joined.

See Bioconjugation and Cross-coupling reaction

Cyclooctyne

Cyclooctyne is the cycloalkyne with a formula.

See Bioconjugation and Cyclooctyne

Cysteine

Cysteine (symbol Cys or C) is a semiessential proteinogenic amino acid with the formula.

See Bioconjugation and Cysteine

Dehydration reaction

In chemistry, a dehydration reaction is a chemical reaction that involves the loss of water from the reacting molecule or ion.

See Bioconjugation and Dehydration reaction

Deprotonation

Deprotonation (or dehydronation) is the removal (transfer) of a proton (or hydron, or hydrogen cation), (H+) from a Brønsted–Lowry acid in an acid–base reaction.

See Bioconjugation and Deprotonation

Dialkylbiaryl phosphine ligands

Dialkylbiaryl phosphine ligands are phosphine ligands that are used in homogeneous catalysis.

See Bioconjugation and Dialkylbiaryl phosphine ligands

Diazonium compound

Diazonium compounds or diazonium salts are a group of organic compounds sharing a common functional group where R can be any organic group, such as an alkyl or an aryl, and X is an inorganic or organic anion, such as a halide.

See Bioconjugation and Diazonium compound

Disulfide

In chemistry, a disulfide (or disulphide in British English) is a compound containing a functional group or the anion.

See Bioconjugation and Disulfide

Electron-withdrawing group

An electron-withdrawing group (EWG) is a group or atom that has the ability to draw electron density toward itself and away from other adjacent atoms. Bioconjugation and electron-withdrawing group are chemical bonding.

See Bioconjugation and Electron-withdrawing group

Electrophile

In chemistry, an electrophile is a chemical species that forms bonds with nucleophiles by accepting an electron pair.

See Bioconjugation and Electrophile

Electrophilic aromatic substitution

Electrophilic aromatic substitution (SEAr) is an organic reaction in which an atom that is attached to an aromatic system (usually hydrogen) is replaced by an electrophile.

See Bioconjugation and Electrophilic aromatic substitution

Enzyme

Enzymes are proteins that act as biological catalysts by accelerating chemical reactions.

See Bioconjugation and Enzyme

Ester

In chemistry, an ester is a functional group derived from an acid (organic or inorganic) in which the hydrogen atom (H) of at least one acidic hydroxyl group of that acid is replaced by an organyl group.

See Bioconjugation and Ester

Exogeny

In a variety of contexts, exogeny or exogeneity is the fact of an action or object originating externally.

See Bioconjugation and Exogeny

Expanded genetic code

An expanded genetic code is an artificially modified genetic code in which one or more specific codons have been re-allocated to encode an amino acid that is not among the 22 common naturally-encoded proteinogenic amino acids.

See Bioconjugation and Expanded genetic code

Fluorine

Fluorine is a chemical element; it has symbol F and atomic number 9.

See Bioconjugation and Fluorine

Fluorophore

A fluorophore (or fluorochrome, similarly to a chromophore) is a fluorescent chemical compound that can re-emit light upon light excitation.

See Bioconjugation and Fluorophore

Functional group

In organic chemistry, a functional group is a substituent or moiety in a molecule that causes the molecule's characteristic chemical reactions.

See Bioconjugation and Functional group

Gemtuzumab ozogamicin

Gemtuzumab ozogamicin, sold under the brand name Mylotarg, is an antibody-drug conjugate (a drug-linked monoclonal antibody) that is used to treat acute myeloid leukemia.

See Bioconjugation and Gemtuzumab ozogamicin

Glycine

Glycine (symbol Gly or G) is an amino acid that has a single hydrogen atom as its side chain.

See Bioconjugation and Glycine

Heck reaction

The Heck reaction (also called the Mizoroki–Heck reaction) is the chemical reaction of an unsaturated halide (or triflate) with an alkene in the presence of a base and a palladium catalyst to form a substituted alkene.

See Bioconjugation and Heck reaction

Hydrazine

Hydrazine is an inorganic compound with the chemical formula.

See Bioconjugation and Hydrazine

Hydrazone

Hydrazones are a class of organic compounds with the structure.

See Bioconjugation and Hydrazone

Hydroxy group

In chemistry, a hydroxy or hydroxyl group is a functional group with the chemical formula and composed of one oxygen atom covalently bonded to one hydrogen atom.

See Bioconjugation and Hydroxy group

Imaging

Imaging is the representation or reproduction of an object's form; especially a visual representation (i.e., the formation of an image).

See Bioconjugation and Imaging

Iminophosphorane

Iminophosphorane is a kind of organophosphorus compound with the formula.

See Bioconjugation and Iminophosphorane

Immunofluorescence

Immunofluorescence (IF) is a light microscopy-based technique that allows detection and localization of a wide variety of target biomolecules within a cell or tissue at a quantitative level.

See Bioconjugation and Immunofluorescence

In situ cyclization of proteins

The in situ cyclization of proteins (INCYPRO) is a protein engineering technology that increases the durability of proteins and enzymes for biotechnological and biomedical applications.

See Bioconjugation and In situ cyclization of proteins

Iodoacetamide

Iodoacetamide (IAA) is an organic compound with the chemical formula.

See Bioconjugation and Iodoacetamide

Isocyanate

In organic chemistry, isocyanate is the functional group with the formula.

See Bioconjugation and Isocyanate

Isothiocyanate

In organic chemistry, isothiocyanate is a functional group as found in compounds with the formula.

See Bioconjugation and Isothiocyanate

Karl Barry Sharpless

Karl Barry Sharpless (born April 28, 1941) is an American stereochemist.

See Bioconjugation and Karl Barry Sharpless

Ketone

In organic chemistry, a ketone is an organic compound with the structure, where R and R' can be a variety of carbon-containing substituents.

See Bioconjugation and Ketone

List of synthetic polymers

Some familiar household synthetic polymers include: Nylons in textiles and fabrics, Teflon in non-stick pans, Bakelite for electrical switches, polyvinyl chloride (PVC) in pipes, etc.

See Bioconjugation and List of synthetic polymers

Lysine

Lysine (symbol Lys or K) is an α-amino acid that is a precursor to many proteins.

See Bioconjugation and Lysine

Maleimide

Maleimide is a chemical compound with the formula H2C2(CO)2NH (see diagram).

See Bioconjugation and Maleimide

Mannich reaction

In organic chemistry, the Mannich reaction is a three-component organic reaction that involves the amino alkylation of an acidic proton next to a carbonyl functional group by formaldehyde and a primary or secondary amine or ammonia.

See Bioconjugation and Mannich reaction

Medication

A medication (also called medicament, medicine, pharmaceutical drug, medicinal drug or simply drug) is a drug used to diagnose, cure, treat, or prevent disease.

See Bioconjugation and Medication

Metal-phosphine complex

A metal-phosphine complex is a coordination complex containing one or more phosphine ligands.

See Bioconjugation and Metal-phosphine complex

N-Hydroxysuccinimide

N-Hydroxysuccinimide (NHS) is an organic compound with the formula (CH2CO)2NOH.

See Bioconjugation and N-Hydroxysuccinimide

N-terminus

The N-terminus (also known as the amino-terminus, NH2-terminus, N-terminal end or amine-terminus) is the start of a protein or polypeptide, referring to the free amine group (-NH2) located at the end of a polypeptide.

See Bioconjugation and N-terminus

Nanotechnology

Nanotechnology is the manipulation of matter with at least one dimension sized from 1 to 100 nanometers (nm).

See Bioconjugation and Nanotechnology

Nanotechnology (journal)

Nanotechnology is a peer-reviewed scientific journal published by IOP Publishing.

See Bioconjugation and Nanotechnology (journal)

Native chemical ligation

Native Chemical Ligation (NCL) is an important extension of the chemical ligation concept for constructing a larger polypeptide chain by the covalent condensation of two or more unprotected peptides segments.

See Bioconjugation and Native chemical ligation

Non-proteinogenic amino acids

In biochemistry, non-coded or non-proteinogenic amino acids are distinct from the 22 proteinogenic amino acids (21 in eukaryotesplus formylmethionine in eukaryotes with prokaryote organelles like mitochondria), which are naturally encoded in the genome of organisms for the assembly of proteins.

See Bioconjugation and Non-proteinogenic amino acids

Nucleic acid

Nucleic acids are large biomolecules that are crucial in all cells and viruses.

See Bioconjugation and Nucleic acid

Nucleophile

In chemistry, a nucleophile is a chemical species that forms bonds by donating an electron pair.

See Bioconjugation and Nucleophile

Olefin metathesis

In organic chemistry, olefin metathesis is an organic reaction that entails the redistribution of fragments of alkenes (olefins) by the scission and regeneration of carbon-carbon double bonds.

See Bioconjugation and Olefin metathesis

Oligosaccharide

An oligosaccharide is a saccharide polymer containing a small number (typically three to ten) of monosaccharides (simple sugars).

See Bioconjugation and Oligosaccharide

Organic azide

An organic azide is an organic compound that contains an azide (–) functional group.

See Bioconjugation and Organic azide

Organometallic chemistry

Organometallic chemistry is the study of organometallic compounds, chemical compounds containing at least one chemical bond between a carbon atom of an organic molecule and a metal, including alkali, alkaline earth, and transition metals, and sometimes broadened to include metalloids like boron, silicon, and selenium, as well.

See Bioconjugation and Organometallic chemistry

Organosulfur chemistry

Organosulfur chemistry is the study of the properties and synthesis of organosulfur compounds, which are organic compounds that contain sulfur.

See Bioconjugation and Organosulfur chemistry

Oxidative addition

Oxidative addition and reductive elimination are two important and related classes of reactions in organometallic chemistry.

See Bioconjugation and Oxidative addition

Oxime

In organic chemistry, an oxime is an organic compound belonging to the imines, with the general formula, where R is an organic side-chain and R' may be hydrogen, forming an aldoxime, or another organic group, forming a ketoxime.

See Bioconjugation and Oxime

Peptide synthesis

In organic chemistry, peptide synthesis is the production of peptides, compounds where multiple amino acids are linked via amide bonds, also known as peptide bonds. Bioconjugation and peptide synthesis are biochemistry.

See Bioconjugation and Peptide synthesis

PH

In chemistry, pH, also referred to as acidity or basicity, historically denotes "potential of hydrogen" (or "power of hydrogen").

See Bioconjugation and PH

Phenols

In organic chemistry, phenols, sometimes called phenolics, are a class of chemical compounds consisting of one or more hydroxyl groups (−O H) bonded directly to an aromatic hydrocarbon group.

See Bioconjugation and Phenols

Polyethylene glycol

Polyethylene glycol (PEG) is a polyether compound derived from petroleum with many applications, from industrial manufacturing to medicine.

See Bioconjugation and Polyethylene glycol

Preclinical imaging

Preclinical imaging is the visualization of living animals for research purposes, such as drug development.

See Bioconjugation and Preclinical imaging

Protein

Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues.

See Bioconjugation and Protein

Protein structure

Protein structure is the three-dimensional arrangement of atoms in an amino acid-chain molecule.

See Bioconjugation and Protein structure

Pyridoxal phosphate

Pyridoxal phosphate (PLP, pyridoxal 5'-phosphate, P5P), the active form of vitamin B6, is a coenzyme in a variety of enzymatic reactions.

See Bioconjugation and Pyridoxal phosphate

Quantum dot

Quantum dots (QDs) or semiconductor nanocrystals are semiconductor particles a few nanometres in size with optical and electronic properties that differ from those of larger particles via quantum mechanical effects.

See Bioconjugation and Quantum dot

Rate equation

In chemistry, the rate equation (also known as the rate law or empirical differential rate equation) is an empirical differential mathematical expression for the reaction rate of a given reaction in terms of concentrations of chemical species and constant parameters (normally rate coefficients and partial orders of reaction) only.

See Bioconjugation and Rate equation

Rate-determining step

In chemical kinetics, the overall rate of a reaction is often approximately determined by the slowest step, known as the rate-determining step (RDS or RD-step or r/d step) or rate-limiting step.

See Bioconjugation and Rate-determining step

Reaction rate

The reaction rate or rate of reaction is the speed at which a chemical reaction takes place, defined as proportional to the increase in the concentration of a product per unit time and to the decrease in the concentration of a reactant per unit time.

See Bioconjugation and Reaction rate

Redox

Redox (reduction–oxidation or oxidation–reduction) is a type of chemical reaction in which the oxidation states of the reactants change.

See Bioconjugation and Redox

Reducing agent

In chemistry, a reducing agent (also known as a reductant, reducer, or electron donor) is a chemical species that "donates" an electron to an (called the,,, or). Examples of substances that are common reducing agents include hydrogen, the alkali metals, formic acid, oxalic acid, and sulfite compounds.

See Bioconjugation and Reducing agent

Room temperature

Room temperature, colloquially, denotes the range of air temperatures most people find comfortable indoors while dressed in typical clothing.

See Bioconjugation and Room temperature

Schiff base

In organic chemistry, a Schiff base (named after Hugo Schiff) is a compound with the general structure (.

See Bioconjugation and Schiff base

Serine

Serine (symbol Ser or S) is an α-amino acid that is used in the biosynthesis of proteins.

See Bioconjugation and Serine

Solubility

In chemistry, solubility is the ability of a substance, the solute, to form a solution with another substance, the solvent.

See Bioconjugation and Solubility

Sonogashira coupling

The Sonogashira reaction is a cross-coupling reaction used in organic synthesis to form carbon–carbon bonds.

See Bioconjugation and Sonogashira coupling

SpyCatcher

The SpyTag/SpyCatcher system is a technology for irreversible conjugation of recombinant proteins.

See Bioconjugation and SpyCatcher

Staudinger reaction

The Staudinger reaction is a chemical reaction of an organic azide with a phosphine or phosphite produces an iminophosphorane.

See Bioconjugation and Staudinger reaction

Structural isomer

In chemistry, a structural isomer (or constitutional isomer in the IUPAC nomenclature) of a compound is another compound whose molecule has the same number of atoms of each element, but with logically distinct bonds between them.

See Bioconjugation and Structural isomer

Substrate (chemistry)

In chemistry, the term substrate is highly context-dependent.

See Bioconjugation and Substrate (chemistry)

Suzuki reaction

The Suzuki reaction or Suzuki coupling is an organic reaction that uses a palladium complex catalyst to cross-couple a boronic acid to an organohalide.

See Bioconjugation and Suzuki reaction

Tetrahedral carbonyl addition compound

A tetrahedral intermediate is a reaction intermediate in which the bond arrangement around an initially double-bonded carbon atom has been transformed from trigonal to tetrahedral.

See Bioconjugation and Tetrahedral carbonyl addition compound

Thermodynamic potential

A thermodynamic potential (or more accurately, a thermodynamic potential energy)ISO/IEC 80000-5, Quantities an units, Part 5 - Thermodynamics, item 5-20.4 Helmholtz energy, Helmholtz functionISO/IEC 80000-5, Quantities an units, Part 5 - Thermodynamics, item 5-20.5, Gibbs energy, Gibbs function is a scalar quantity used to represent the thermodynamic state of a system.

See Bioconjugation and Thermodynamic potential

Thiazolidine

Thiazolidine is a heterocyclic organic compound with the formula (CH2)3(NH)S.

See Bioconjugation and Thiazolidine

Thioester

In organic chemistry, thioesters are organosulfur compounds with the molecular structure.

See Bioconjugation and Thioester

Thiol

In organic chemistry, a thiol, or thiol derivative, is any organosulfur compound of the form, where R represents an alkyl or other organic substituent.

See Bioconjugation and Thiol

Threonine

Threonine (symbol Thr or T) is an amino acid that is used in the biosynthesis of proteins.

See Bioconjugation and Threonine

Toxicity

Toxicity is the degree to which a chemical substance or a particular mixture of substances can damage an organism.

See Bioconjugation and Toxicity

Transamination

Transamination is a chemical reaction that transfers an amino group to a ketoacid to form new amino acids.This pathway is responsible for the deamination of most amino acids.

See Bioconjugation and Transamination

Transition metal

In chemistry, a transition metal (or transition element) is a chemical element in the d-block of the periodic table (groups 3 to 12), though the elements of group 12 (and less often group 3) are sometimes excluded.

See Bioconjugation and Transition metal

Transition state

In chemistry, the transition state of a chemical reaction is a particular configuration along the reaction coordinate.

See Bioconjugation and Transition state

Triazole

A triazole is a heterocyclic compound featuring a five-membered ring of two carbon atoms and three nitrogen atoms with molecular formula C2H3N3.

See Bioconjugation and Triazole

Triphenylphosphine

Triphenylphosphine (IUPAC name: triphenylphosphane) is a common organophosphorus compound with the formula P(C6H5)3 and often abbreviated to PPh3 or Ph3P.

See Bioconjugation and Triphenylphosphine

Tryptophan

Tryptophan (symbol Trp or W) is an α-amino acid that is used in the biosynthesis of proteins.

See Bioconjugation and Tryptophan

Tyrosine

-Tyrosine or tyrosine (symbol Tyr or Y) or 4-hydroxyphenylalanine is one of the 20 standard amino acids that are used by cells to synthesize proteins.

See Bioconjugation and Tyrosine

Ylide

An ylide or ylid is a neutral dipolar molecule containing a formally negatively charged atom (usually a carbanion) directly attached to a heteroatom with a formal positive charge (usually nitrogen, phosphorus or sulfur), and in which both atoms have full octets of electrons.

See Bioconjugation and Ylide

3-Arylpropiolonitriles

3-Arylpropiolonitriles (APN) belong to a class of electron-deficient alkyne derivatives substituted by two electron-withdrawing groups – a nitrile and an aryl moieties.

See Bioconjugation and 3-Arylpropiolonitriles

4-Phenyl-1,2,4-triazole-3,5-dione

4-Phenyl-1,2,4-triazoline-3,5-dione (PTAD) is an azodicarbonyl compound.

See Bioconjugation and 4-Phenyl-1,2,4-triazole-3,5-dione

References

[1] https://en.wikipedia.org/wiki/Bioconjugation

Also known as Bioconjugate, Conjugation (biochemistry).

, Expanded genetic code, Fluorine, Fluorophore, Functional group, Gemtuzumab ozogamicin, Glycine, Heck reaction, Hydrazine, Hydrazone, Hydroxy group, Imaging, Iminophosphorane, Immunofluorescence, In situ cyclization of proteins, Iodoacetamide, Isocyanate, Isothiocyanate, Karl Barry Sharpless, Ketone, List of synthetic polymers, Lysine, Maleimide, Mannich reaction, Medication, Metal-phosphine complex, N-Hydroxysuccinimide, N-terminus, Nanotechnology, Nanotechnology (journal), Native chemical ligation, Non-proteinogenic amino acids, Nucleic acid, Nucleophile, Olefin metathesis, Oligosaccharide, Organic azide, Organometallic chemistry, Organosulfur chemistry, Oxidative addition, Oxime, Peptide synthesis, PH, Phenols, Polyethylene glycol, Preclinical imaging, Protein, Protein structure, Pyridoxal phosphate, Quantum dot, Rate equation, Rate-determining step, Reaction rate, Redox, Reducing agent, Room temperature, Schiff base, Serine, Solubility, Sonogashira coupling, SpyCatcher, Staudinger reaction, Structural isomer, Substrate (chemistry), Suzuki reaction, Tetrahedral carbonyl addition compound, Thermodynamic potential, Thiazolidine, Thioester, Thiol, Threonine, Toxicity, Transamination, Transition metal, Transition state, Triazole, Triphenylphosphine, Tryptophan, Tyrosine, Ylide, 3-Arylpropiolonitriles, 4-Phenyl-1,2,4-triazole-3,5-dione.