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Biological functions of nitric oxide

Index Biological functions of nitric oxide

Nitric oxide (nitrogen monoxide) is a molecule and chemical compound with chemical formula of NO. [1]

134 relations: Acetylcholine, Aconitase, Acute respiratory distress syndrome, American Journal of Physiology, Amputation, Amyl nitrite, Angina, Antianginal, AoB Plants, Apoptosis, Arginine, Asthma, Atherosclerosis, Auxin, Bed bug, Beetroot, Biofilm, BioMetals (journal), Blood gas tension, Breakthrough of the Year, Breath test, Calcium, Calmodulin, Cardiac muscle, Cell signaling, CGMP-dependent protein kinase, CGMP-specific phosphodiesterase type 5, Chemical compound, Chemical formula, Chloroplast, Citrulline, Clinical Chemistry (journal), Clinical Pharmacology & Therapeutics, Clitoris, Current Pharmaceutical Design, Cyclic guanosine monophosphate, Cysteine, Cytokine, Cytokinin, DASH diet, Deinococcus radiodurans, Denitrification, Diabetes mellitus, Dinitrosyl iron complex, Encyclopedia of Earth, Endothelial NOS, Environmental Health (journal), Erectile tissue, Erection, Eruca sativa, ..., Exhaled nitric oxide, Extracorporeal membrane oxygenation, Gastrointestinal tract, Guanidine, Guanosine monophosphate, Heart failure, Heart rate, Homeostasis, Hypertension, Hypotension, Immune response, Immunology, Infant, Interferon gamma, Interleukin, Ischemia, Leishmania, Macrophage, Malaria, Metal nitrosyl complex, Metalloprotein, Methemoglobin, Minoxidil, Mitochondrion, Molecule, Monocyte, National Council for Science and the Environment, Nature Medicine, Nature Reviews Drug Discovery, Necrosis, Neuroscience, Neurotransmitter, Neutrophil, NF-κB, Nitrate, Nitrate reductase, Nitric oxide, Nitric Oxide (journal), Nitric oxide synthase, Nitrogen, Nitrogen fixation, Nitroglycerin, Nitroglycerin (drug), Nitrophorin, Nitrosation, Organelle, Oxidative stress, Oxygen, Paraquat, Penis, Peripheral neuropathy, Peroxisome, Peroxynitrite, Physiology, Plant hormone, Plant nutrition, Plant pathology, Platelet, Proceedings of the National Academy of Sciences of the United States of America, Protein isoform, Pulmonary embolism, Pulmonary hypertension, Reperfusion injury, Respiratory tract, Ribonucleotide reductase, Root, Root hair, Root nodule, Saliva testing, Salvage therapy, Shear stress, Sildenafil, Smooth muscle tissue, Specialized pro-resolving mediators, Spinach, Stoma, Superoxide, Thiol, Transforming growth factor beta, Triatominae, Tumor necrosis factor superfamily, Unpaired electron, Vascular plant, Vasodilation. Expand index (84 more) »

Acetylcholine

Acetylcholine (ACh) is an organic chemical that functions in the brain and body of many types of animals, including humans, as a neurotransmitter—a chemical message released by nerve cells to send signals to other cells.

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Aconitase

Aconitase (aconitate hydratase) is an enzyme that catalyses the stereo-specific isomerization of citrate to isocitrate via cis-aconitate in the tricarboxylic acid cycle, a non-redox-active process.

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Acute respiratory distress syndrome

Acute respiratory distress syndrome (ARDS) is a medical condition occurring in critically ill or critically wounded patients characterized by widespread inflammation in the lungs.

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American Journal of Physiology

The American Journal of Physiology is a peer-reviewed scientific journal on physiology published by the American Physiological Society.

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Amputation

Amputation is the removal of a limb by trauma, medical illness, or surgery.

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Amyl nitrite

Amyl nitrite is a chemical compound with the formula C5H11ONO.

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Angina

Angina, also known as angina pectoris, is chest pain or pressure, usually due to not enough blood flow to the heart muscle.

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Antianginal

An antianginal is any drug used in the treatment of angina pectoris, a symptom of ischaemic heart disease.

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AoB Plants

AoB Plants is a peer-reviewed open-access non-profit scientific journal established in 2009 and published by Oxford University Press.

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Apoptosis

Apoptosis (from Ancient Greek ἀπόπτωσις "falling off") is a process of programmed cell death that occurs in multicellular organisms.

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Arginine

Arginine (symbol Arg or R) is an α-amino acid that is used in the biosynthesis of proteins.

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Asthma

Asthma is a common long-term inflammatory disease of the airways of the lungs.

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Atherosclerosis

Atherosclerosis is a disease in which the inside of an artery narrows due to the build up of plaque.

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Auxin

Auxins (plural of auxin) are a class of plant hormones (or plant growth regulators) with some morphogen-like characteristics.

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Bed bug

Bed bugs are parasitic insects in the genus Cimex that feed exclusively on blood.

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Beetroot

The beetroot is the taproot portion of the beet plant, usually known in North America as the beet, also table beet, garden beet, red beet, or golden beet.

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Biofilm

A biofilm comprises any group of microorganisms in which cells stick to each other and often also to a surface.

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BioMetals (journal)

BioMetals is a bimonthly peer-reviewed scientific journal covering the role of metal ions in biological systems.

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Blood gas tension

Blood gas tension refers to the partial pressure of gases in blood.

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Breakthrough of the Year

The Breakthrough of the Year is an annual award made by the AAAS journal, Science, for the most significant development in scientific research.

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Breath test

A breath test is a type of test performed on air generated from the act of exhalation.

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Calcium

Calcium is a chemical element with symbol Ca and atomic number 20.

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Calmodulin

Calmodulin (CaM) (an abbreviation for calcium-modulated protein) is a multifunctional intermediate calcium-binding messenger protein expressed in all eukaryotic cells.

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Cardiac muscle

Cardiac muscle (heart muscle) is one of the three major types of muscle, the others being skeletal and smooth muscle.

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Cell signaling

Cell signaling (cell signalling in British English) is part of any communication process that governs basic activities of cells and coordinates all cell actions.

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CGMP-dependent protein kinase

cGMP-dependent protein kinase or Protein Kinase G (PKG) is a serine/threonine-specific protein kinase that is activated by cGMP.

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CGMP-specific phosphodiesterase type 5

cGMP-specific phosphodiesterase type 5 is an enzyme from the phosphodiesterase class.

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Chemical compound

A chemical compound is a chemical substance composed of many identical molecules (or molecular entities) composed of atoms from more than one element held together by chemical bonds.

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Chemical formula

A chemical formula is a way of presenting information about the chemical proportions of atoms that constitute a particular chemical compound or molecule, using chemical element symbols, numbers, and sometimes also other symbols, such as parentheses, dashes, brackets, commas and plus (+) and minus (−) signs.

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Chloroplast

Chloroplasts are organelles, specialized compartments, in plant and algal cells.

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Citrulline

The organic compound citrulline is an α-amino acid.

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Clinical Chemistry (journal)

Clinical Chemistry is a peer-reviewed medical journal covering the field of clinical chemistry.

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Clinical Pharmacology & Therapeutics

Clinical Pharmacology & Therapeutics is a monthly peer-reviewed medical journal which covers research on the nature, action, efficacy, and evaluation of therapeutics.

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Clitoris

The clitoris is a female sex organ present in mammals, ostriches and a limited number of other animals.

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Current Pharmaceutical Design

Current Pharmaceutical Design is a peer-reviewed medical journal which covers issues related to pharmacology and medicinal chemistry.

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Cyclic guanosine monophosphate

Cyclic guanosine monophosphate (cGMP) is a cyclic nucleotide derived from guanosine triphosphate (GTP).

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Cysteine

Cysteine (symbol Cys or C) is a semi-essential proteinogenic amino acid with the formula HO2CCH(NH2)CH2SH.

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Cytokine

Cytokines are a broad and loose category of small proteins (~5–20 kDa) that are important in cell signaling.

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Cytokinin

Cytokinins (CK) are a class of plant growth substances (phytohormones) that promote cell division, or cytokinesis, in plant roots and shoots.

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DASH diet

The DASH diet (Dietary Approaches to Stop Hypertension) is a dietary pattern promoted by the U.S.-based National Heart, Lung, and Blood Institute (part of the National Institutes of Health (NIH), an agency of the United States Department of Health and Human Services) to prevent and control hypertension.

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Deinococcus radiodurans

Deinococcus radiodurans is an extremophilic bacterium, one of the most radiation-resistant organisms known.

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Denitrification

Denitrification is a microbially facilitated process where nitrate is reduced and ultimately produces molecular nitrogen (N2) through a series of intermediate gaseous nitrogen oxide products.

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Diabetes mellitus

Diabetes mellitus (DM), commonly referred to as diabetes, is a group of metabolic disorders in which there are high blood sugar levels over a prolonged period.

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Dinitrosyl iron complex

In biochemistry, dinitrosyl iron complexes (DNIC's) are coordination complexes with the formula −. Together with Roussin esters (Fe2(NO)4(SR)2), they result from the degradation of iron-sulfur proteins by nitric oxide.

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Encyclopedia of Earth

The Encyclopedia of Earth (abbreviated EoE) is an electronic reference about the Earth, its natural environments, and their interaction with society.

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Endothelial NOS

Endothelial NOS (eNOS), also known as nitric oxide synthase 3 (NOS3) or constitutive NOS (cNOS), is an enzyme that in humans is encoded by the NOS3 gene located in the 7q35-7q36 region of chromosome 7.

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Environmental Health (journal)

Environmental Health is a peer-reviewed medical journal established in 2002 and published by BioMed Central.

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Erectile tissue

Erectile tissue is tissue in the body with numerous vascular spaces that may become engorged with blood.

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Erection

An erection (clinically: penile erection or penile tumescence) is a physiological phenomenon in which the penis becomes firm, engorged, and enlarged.

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Eruca sativa

Arugula or rocket (Eruca sativa; syns. E. vesicaria subsp. sativa (Miller) Thell., Brassica eruca L.) is an edible annual plant in the Brassicaceae family used as a leaf vegetable for its fresh peppery flavor.

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Exhaled nitric oxide

In medicine, exhaled nitric oxide (eNO) can be measured in a breath test for asthma or other conditions characterized by airway inflammation.

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Extracorporeal membrane oxygenation

Extracorporeal membrane oxygenation (ECMO), also known as extracorporeal life support (ECLS), is an extracorporeal technique of providing prolonged cardiac and respiratory support to persons whose heart and lungs are unable to provide an adequate amount of gas exchange or perfusion to sustain life.

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Gastrointestinal tract

The gastrointestinal tract (digestive tract, digestional tract, GI tract, GIT, gut, or alimentary canal) is an organ system within humans and other animals which takes in food, digests it to extract and absorb energy and nutrients, and expels the remaining waste as feces.

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Guanidine

Guanidine is the compound with the formula HNC(NH2)2.

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Guanosine monophosphate

Guanosine monophosphate (GMP), also known as 5'-guanidylic acid or guanylic acid (conjugate base guanylate), is a nucleotide that is used as a monomer in RNA.

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Heart failure

Heart failure (HF), often referred to as congestive heart failure (CHF), is when the heart is unable to pump sufficiently to maintain blood flow to meet the body's needs.

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Heart rate

Heart rate is the speed of the heartbeat measured by the number of contractions of the heart per minute (bpm).

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Homeostasis

Homeostasis is the tendency of organisms to auto-regulate and maintain their internal environment in a stable state.

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Hypertension

Hypertension (HTN or HT), also known as high blood pressure (HBP), is a long-term medical condition in which the blood pressure in the arteries is persistently elevated.

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Hypotension

Hypotension is low blood pressure, especially in the arteries of the systemic circulation.

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Immune response

The Immune response is the body's response caused by its immune system being activated by antigens.

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Immunology

Immunology is a branch of biology that covers the study of immune systems in all organisms.

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Infant

An infant (from the Latin word infans, meaning "unable to speak" or "speechless") is the more formal or specialised synonym for "baby", the very young offspring of a human.

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Interferon gamma

Interferon gamma (IFNγ) is a dimerized soluble cytokine that is the only member of the type II class of interferons.

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Interleukin

Interleukins (ILs) are a group of cytokines (secreted proteins and signal molecules) that were first seen to be expressed by white blood cells (leukocytes).

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Ischemia

Ischemia or ischaemia is a restriction in blood supply to tissues, causing a shortage of oxygen that is needed for cellular metabolism (to keep tissue alive).

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Leishmania

Leishmania is a genus of trypanosomes that are responsible for the disease leishmaniasis.

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Macrophage

Macrophages (big eaters, from Greek μακρός (makrós).

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Malaria

Malaria is a mosquito-borne infectious disease affecting humans and other animals caused by parasitic protozoans (a group of single-celled microorganisms) belonging to the Plasmodium type.

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Metal nitrosyl complex

Sodium nitroprusside, a medicinally significant metal nitrosyl compound. Metal nitrosyl complexes are complexes that contain nitric oxide, NO, bonded to a transition metal.

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Metalloprotein

Metalloprotein is a generic term for a protein that contains a metal ion cofactor.

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Methemoglobin

Methemoglobin (English: methaemoglobin) (pronounced "met-hemoglobin") is a form of the oxygen-carrying metalloprotein hemoglobin, in which the iron in the heme group is in the Fe3+ (ferric) state, not the Fe2+ (ferrous) of normal hemoglobin.

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Minoxidil

No description.

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Mitochondrion

The mitochondrion (plural mitochondria) is a double-membrane-bound organelle found in most eukaryotic organisms.

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Molecule

A molecule is an electrically neutral group of two or more atoms held together by chemical bonds.

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Monocyte

Monocytes are a type of leukocyte, or white blood cell.

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National Council for Science and the Environment

The National Council for Science and the Environment (NCSE) is a U.S.-based non-profit organization which has a mission to improve the scientific basis for environmental decision-making.

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Nature Medicine

Nature Medicine is a monthly peer-reviewed medical journal publishing research articles, reviews, news and commentaries in the biomedical area, including both basic research and early-phase clinical research covering all aspects of medicine.

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Nature Reviews Drug Discovery

Nature Reviews Drug Discovery is a peer-reviewed review journal covering drug discovery and development.

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Necrosis

Necrosis (from the Greek νέκρωσις "death, the stage of dying, the act of killing" from νεκρός "dead") is a form of cell injury which results in the premature death of cells in living tissue by autolysis.

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Neuroscience

Neuroscience (or neurobiology) is the scientific study of the nervous system.

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Neurotransmitter

Neurotransmitters are endogenous chemicals that enable neurotransmission.

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Neutrophil

Neutrophils (also known as neutrocytes) are the most abundant type of granulocytes and the most abundant (40% to 70%) type of white blood cells in most mammals.

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NF-κB

NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) is a protein complex that controls transcription of DNA, cytokine production and cell survival.

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Nitrate

Nitrate is a polyatomic ion with the molecular formula and a molecular mass of 62.0049 u.

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Nitrate reductase

Nitrate reductases are molybdoenzymes that reduce nitrate (NO) to nitrite (NO).

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Nitric oxide

Nitric oxide (nitrogen oxide or nitrogen monoxide) is a colorless gas with the formula NO.

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Nitric Oxide (journal)

Nitric Oxide is a peer-reviewed scientific journal and official journal of the Nitric Oxide Society.

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Nitric oxide synthase

Nitric oxide synthases (NOSs) are a family of enzymes catalyzing the production of nitric oxide (NO) from L-arginine.

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Nitrogen

Nitrogen is a chemical element with symbol N and atomic number 7.

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Nitrogen fixation

Nitrogen fixation is a process by which nitrogen in the Earth's atmosphere is converted into ammonia (NH3) or other molecules available to living organisms.

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Nitroglycerin

Nitroglycerin (NG), also known as nitroglycerine, trinitroglycerin (TNG), trinitroglycerine, nitro, glyceryl trinitrate (GTN), or 1,2,3-trinitroxypropane, is a heavy, colorless, oily, explosive liquid most commonly produced by nitrating glycerol with white fuming nitric acid under conditions appropriate to the formation of the nitric acid ester.

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Nitroglycerin (drug)

Nitroglycerin, also known as glyceryl trinitrate (GTN), is a medication used for heart failure, high blood pressure, and to treat and prevent chest pain from not enough blood flow to the heart (angina) or due to cocaine.

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Nitrophorin

Nitrophorins are hemoproteins found in the saliva of blood-feeding insects.

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Nitrosation

Nitrosation is a process of converting organic compounds into nitroso derivatives, i.e. compounds containing the R-NO functionality.

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Organelle

In cell biology, an organelle is a specialized subunit within a cell that has a specific function, in which their function is vital for the cell to live.

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Oxidative stress

Oxidative stress reflects an imbalance between the systemic manifestation of reactive oxygen species and a biological system's ability to readily detoxify the reactive intermediates or to repair the resulting damage.

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Oxygen

Oxygen is a chemical element with symbol O and atomic number 8.

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Paraquat

Paraquat (trivial name) or N,N′-dimethyl-4,4′-bipyridinium dichloride (systematic name) is an organic compound with the chemical formula Cl2.

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Penis

A penis (plural penises or penes) is the primary sexual organ that male animals use to inseminate sexually receptive mates (usually females and hermaphrodites) during copulation.

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Peripheral neuropathy

Peripheral neuropathy (PN) is damage to or disease affecting nerves, which may impair sensation, movement, gland or organ function, or other aspects of health, depending on the type of nerve affected.

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Peroxisome

A peroxisome is a type of organelle known as a microbody, found in virtually all eukaryotic cells.

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Peroxynitrite

Peroxynitrite (sometimes called peroxonitrite) is an ion with the formula ONOO−.

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Physiology

Physiology is the scientific study of normal mechanisms, and their interactions, which work within a living system.

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Plant hormone

Plant hormones (also known as phytohormones) are chemicals that regulate plant growth.

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Plant nutrition

Plant nutrition is the study of the chemical elements and compounds necessary for plant growth, plant metabolism and their external supply.

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Plant pathology

Plant pathology (also phytopathology) is the scientific study of diseases in plants caused by pathogens (infectious organisms) and environmental conditions (physiological factors).

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Platelet

Platelets, also called thrombocytes (from Greek θρόμβος, "clot" and κύτος, "cell"), are a component of blood whose function (along with the coagulation factors) is to react to bleeding from blood vessel injury by clumping, thereby initiating a blood clot.

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Proceedings of the National Academy of Sciences of the United States of America

Proceedings of the National Academy of Sciences of the United States of America (PNAS) is the official scientific journal of the National Academy of Sciences, published since 1915.

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Protein isoform

A protein isoform, or "protein variant" is a member of a set of highly similar proteins that originate from a single gene or gene family and are the result of genetic differences.

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Pulmonary embolism

Pulmonary embolism (PE) is a blockage of an artery in the lungs by a substance that has moved from elsewhere in the body through the bloodstream (embolism).

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Pulmonary hypertension

Pulmonary hypertension (PH or PHTN) is a condition of increased blood pressure within the arteries of the lungs.

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Reperfusion injury

Reperfusion injury or reperfusion insult, sometimes called ischemia-reperfusion injury (IRI) or reoxygenation injury, is the tissue damage caused when blood supply returns to tissue (re- + perfusion) after a period of ischemia or lack of oxygen (anoxia or hypoxia).

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Respiratory tract

In humans, the respiratory tract is the part of the anatomy of the respiratory system involved with the process of respiration.

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Ribonucleotide reductase

Ribonucleotide reductase (RNR), also known as ribonucleoside diphosphate reductase (rNDP), is an enzyme that catalyzes the formation of deoxyribonucleotides from ribonucleotides.

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Root

In vascular plants, the root is the organ of a plant that typically lies below the surface of the soil.

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Root hair

A root hair, or absorbent hair, the rhizoid of a vascular plant, is a tubular outgrowth of a trichoblast, a hair-forming cell on the epidermis of a plant root.

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Root nodule

Root nodules occur on the roots of plants (primarily Fabaceae) that associate with symbiotic nitrogen-fixing bacteria.

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Saliva testing

Saliva testing is a diagnostic technique that involves laboratory analysis of saliva to identify markers of endocrine, immunologic, inflammatory, infectious, and other types of conditions.

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Salvage therapy

Salvage therapy, also known as rescue therapy, is a form of therapy given after an ailment does not respond to standard therapy.

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Shear stress

A shear stress, often denoted by (Greek: tau), is the component of stress coplanar with a material cross section.

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Sildenafil

Sildenafil, sold as the brand name Viagra among others, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension.

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Smooth muscle tissue

Smooth muscle is an involuntary non-striated muscle.

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Specialized pro-resolving mediators

Specialized pro-resolving mediators (SPM, also termed specialized proresolving mediators) are a large and growing class of cell signaling molecules formed in cells by the metabolism of polyunsaturated fatty acids (PUFA) by one or a combination of lipoxygenase, cyclooxygenase, and cytochrome P450 monooxygenase enzymes.

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Spinach

Spinach (Spinacia oleracea) is an edible flowering plant in the family Amaranthaceae native to central and western Asia.

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Stoma

In botany, a stoma (plural "stomata"), also called a stomata (plural "stomates") (from Greek στόμα, "mouth"), is a pore, found in the epidermis of leaves, stems, and other organs, that facilitates gas exchange.

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Superoxide

A superoxide is a compound that contains the superoxide anion, which has the chemical formula.

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Thiol

Thiol is an organosulfur compound that contains a carbon-bonded sulfhydryl (R–SH) group (where R represents an alkyl or other organic substituent).

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Transforming growth factor beta

Transforming growth factor beta (TGF-β) is a multifunctional cytokine belonging to the transforming growth factor superfamily that includes four different isoforms (TGF-β 1 to 4, HGNC symbols TGFB1, TGFB2, TGFB3, TGFB4) and many other signaling proteins produced by all white blood cell lineages.

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Triatominae

The members of Triatominae, a subfamily of Reduviidae, are also known as conenose bugs, kissing bugs (so called from their habit of feeding on the lips of human victims),https://en.wiktionary.org/wiki/kissing_bug assassin bugs, or vampire bugs.

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Tumor necrosis factor superfamily

The tumor necrosis factor (TNF) superfamily is a protein superfamily of type II transmembrane proteins containing TNF homology domain and forming trimers.

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Unpaired electron

In chemistry, an unpaired electron is an electron that occupies an orbital of an atom singly, rather than as part of an electron pair.

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Vascular plant

Vascular plants (from Latin vasculum: duct), also known as tracheophytes (from the equivalent Greek term trachea) and also higher plants, form a large group of plants (c. 308,312 accepted known species) that are defined as those land plants that have lignified tissues (the xylem) for conducting water and minerals throughout the plant.

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Vasodilation

Vasodilation is the widening of blood vessels.

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Redirects here:

Metabolism of nitric oxide.

References

[1] https://en.wikipedia.org/wiki/Biological_functions_of_nitric_oxide

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