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33 relations: Alzheimer's disease, B cell, CDKN2D, Cell cycle, Colorectal cancer, Gene, Glioblastoma, Hedgehog, Hedgehog signaling pathway, Helix-turn-helix, Hematopoietic stem cell, Mantle cell lymphoma, Murine leukemia virus, N-terminus, Notch signaling pathway, Oncogene, Ovarian cancer, P16, P53, Pancreatic cancer, PHC1, PHC2, Polycomb-group proteins, Prostate cancer, Protein, Protein kinase B, Protein–protein interaction, Receptor tyrosine kinase, RING finger domain, RING1, Skin cancer, Wnt signaling pathway, Zinc finger and BTB domain-containing protein 16.
Alzheimer's disease
Alzheimer's disease (AD), also referred to simply as Alzheimer's, is a chronic neurodegenerative disease that usually starts slowly and worsens over time.
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B cell
B cells, also known as B lymphocytes, are a type of white blood cell of the lymphocyte subtype.
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CDKN2D
Cyclin-dependent kinase 4 inhibitor D is an enzyme that in humans is encoded by the CDKN2D gene.
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Cell cycle
The cell cycle or cell-division cycle is the series of events that take place in a cell leading to its division and duplication of its DNA (DNA replication) to produce two daughter cells.
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Colorectal cancer
Colorectal cancer (CRC), also known as bowel cancer and colon cancer, is the development of cancer from the colon or rectum (parts of the large intestine).
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Gene
In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.
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Glioblastoma
Glioblastoma, also known as glioblastoma multiforme (GBM), is the most aggressive cancer that begins within the brain.
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Hedgehog
A hedgehog is any of the spiny mammals of the subfamily Erinaceinae, in the eulipotyphlan family Erinaceidae.
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Hedgehog signaling pathway
The Hedgehog signaling pathway is a signaling pathway that transmits information to embryonic cells required for proper cell differentiation.
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Helix-turn-helix
In proteins, the helix-turn-helix (HTH) is a major structural motif capable of binding DNA.
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Hematopoietic stem cell
Hematopoietic stem cells (HSCs) are the stem cells that give rise to other blood cells.
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Mantle cell lymphoma
Mantle cell lymphoma (MCL) is a type of non-Hodgkin's lymphoma (NHL), comprising about 6% of NHL cases.
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Murine leukemia virus
The murine leukemia viruses (MLVs or MuLVs) are retroviruses named for their ability to cause cancer in murine (mouse) hosts.
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N-terminus
The N-terminus (also known as the amino-terminus, NH2-terminus, N-terminal end or amine-terminus) is the start of a protein or polypeptide referring to the free amine group (-NH2) located at the end of a polypeptide.
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Notch signaling pathway
The Notch signaling pathway is a highly conserved cell signaling system present in most multicellular organisms.
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Oncogene
An oncogene is a gene that has the potential to cause cancer.
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Ovarian cancer
Ovarian cancer is a cancer that forms in or on an ovary.
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P16
p16 (also known as p16INK4a, cyclin-dependent kinase inhibitor 2A, multiple tumor suppressor 1 and as several other synonyms), is a tumor suppressor protein, that in humans is encoded by the CDKN2A gene.
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P53
Tumor protein p53, also known as p53, cellular tumor antigen p53 (UniProt name), phosphoprotein p53, tumor suppressor p53, antigen NY-CO-13, or transformation-related protein 53 (TRP53), is any isoform of a protein encoded by homologous genes in various organisms, such as TP53 (humans) and Trp53 (mice).
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Pancreatic cancer
Pancreatic cancer arises when cells in the pancreas, a glandular organ behind the stomach, begin to multiply out of control and form a mass.
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PHC1
Polyhomeotic-like protein 1 is a protein that in humans is encoded by the PHC1 gene.
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PHC2
Polyhomeotic-like protein 2 is a protein that in humans is encoded by the PHC2 gene.
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Polycomb-group proteins
Polycomb-group proteins are a family of proteins first discovered in fruit flies that can remodel chromatin such that epigenetic silencing of genes takes place.
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Prostate cancer
Prostate cancer is the development of cancer in the prostate, a gland in the male reproductive system.
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Protein
Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.
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Protein kinase B
Protein kinase B (PKB), also known as Akt, is a serine/threonine-specific protein kinase that plays a key role in multiple cellular processes such as glucose metabolism, apoptosis, cell proliferation, transcription and cell migration.
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Protein–protein interaction
Protein–protein interactions (PPIs) are the physical contacts of high specificity established between two or more protein molecules as a result of biochemical events steered by electrostatic forces including the hydrophobic effect.
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Receptor tyrosine kinase
Receptor tyrosine kinases (RTKs) are the high-affinity cell surface receptors for many polypeptide growth factors, cytokines, and hormones.
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RING finger domain
In molecular biology, a RING (Really Interesting New Gene) finger domain is a protein structural domain of zinc finger type which contains a C3HC4 amino acid motif which binds two zinc cations (seven cysteines and one histidine arranged non-consecutively).
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RING1
E3 ubiquitin-protein ligase RING1 is an enzyme that in humans is encoded by the RING1 gene.
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Skin cancer
Skin cancers are cancers that arise from the skin.
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Wnt signaling pathway
The Wnt signaling pathways are a group of signal transduction pathways made of proteins that pass signals into a cell through cell surface receptors.
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Zinc finger and BTB domain-containing protein 16
Zinc finger and BTB domain-containing protein 16 is a protein that in humans is encoded by the ZBTB16 gene.
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References
[1] https://en.wikipedia.org/wiki/BMI1
