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100 relations: Alkaline phosphatase, Allergic inflammation, Amino acid, Apoptosis, Artery, Aspartic acid, Asthma, Atheroma, Autoimmune hepatitis, B cell, Base pair, Bone, Bone marrow, Bone remodeling, Bone sialoprotein, Brain, Breast cancer, Bronchial hyperresponsiveness, Bronchoalveolar lavage, Calciphylaxis, Calcitriol, Cancer, Carbohydrate, Cell (biology), Cell adhesion, Cell adhesion molecule, Chemotaxis, Chondrocyte, Chromosome 4, Colorectal cancer, Crohn's disease, Cytokine, Decidua, Deficiency (medicine), Degranulation, Dendritic cell, Duchenne muscular dystrophy, Ear, Ectopic calcification, Endothelium, Epitope, Exon, Extracellular matrix, Fibroblast, Gene expression, Glomerulonephritis, Glutamic acid, Glycoprotein, Golgi apparatus, Hydroxylapatite, ..., In vitro, Inflammatory bowel disease, Interferon gamma, Interleukin 12, Interleukin 17, Interstitial nephritis, Kidney, Kidney stone disease, Locus (genetics), Lung cancer, Macrophage, Mast cell, Melanoma, Multiple sclerosis, Myocyte, Neutrophil, Odontoblast, Organic compound, Osteoblast, Osteocalcin, Osteoclast, Osteocyte, Osteonectin, Osteoporosis, Osteoprotegerin, Ovarian cancer, Oxalate, PHEX, Phosphorylation, Phosphoserine, Placenta, Pleural cavity, Post-translational modification, Protein, Rheumatoid arthritis, Sialic acid, SIBLING proteins, Signal transduction, Skeletal muscle, Smooth muscle tissue, Sputum, Stomach cancer, T cell, Thrombin, Type I collagen, Ulcerative colitis, Urine, VDRE, White blood cell, Wound healing. Expand index (50 more) »
Alkaline phosphatase
Alkaline phosphatase (ALP, ALKP, ALPase, Alk Phos) or basic phosphatase is a homodimeric protein enzyme of 86 kilodaltons.
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Allergic inflammation
Allergic inflammation is an important pathophysiological feature of several disabilities or medical conditions including allergic asthma, atopic dermatitis, allergic rhinitis and several ocular allergic diseases.
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Amino acid
Amino acids are organic compounds containing amine (-NH2) and carboxyl (-COOH) functional groups, along with a side chain (R group) specific to each amino acid.
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Apoptosis
Apoptosis (from Ancient Greek ἀπόπτωσις "falling off") is a process of programmed cell death that occurs in multicellular organisms.
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Artery
An artery (plural arteries) is a blood vessel that takes blood away from the heart to all parts of the body (tissues, lungs, etc).
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Aspartic acid
Aspartic acid (symbol Asp or D; salts known as aspartates), is an α-amino acid that is used in the biosynthesis of proteins.
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Asthma
Asthma is a common long-term inflammatory disease of the airways of the lungs.
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Atheroma
An atheroma is a reversible accumulation of degenerative material in the inner layer of an artery wall.
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Autoimmune hepatitis
Autoimmune hepatitis, formerly called lupoid hepatitis, is a chronic, autoimmune disease of the liver that occurs when the body's immune system attacks liver cells causing the liver to be inflamed.
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B cell
B cells, also known as B lymphocytes, are a type of white blood cell of the lymphocyte subtype.
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Base pair
A base pair (bp) is a unit consisting of two nucleobases bound to each other by hydrogen bonds.
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Bone
A bone is a rigid organ that constitutes part of the vertebrate skeleton.
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Bone marrow
Bone marrow is a semi-solid tissue which may be found within the spongy or cancellous portions of bones.
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Bone remodeling
Bone remodeling (or bone metabolism) is a lifelong process where mature bone tissue is removed from the skeleton (a process called bone resorption) and new bone tissue is formed (a process called ossification or new bone formation).
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Bone sialoprotein
Bone sialoprotein (BSP) is a component of mineralized tissues such as bone, dentin, cementum and calcified cartilage.
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Brain
The brain is an organ that serves as the center of the nervous system in all vertebrate and most invertebrate animals.
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Breast cancer
Breast cancer is cancer that develops from breast tissue.
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Bronchial hyperresponsiveness
Bronchial hyperresponsiveness (or other combinations with airway or hyperreactivity) is a state characterised by easily triggered bronchospasm (contraction of the bronchioles or small airways).
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Bronchoalveolar lavage
Bronchoalveolar lavage (BAL; informally, "bronchoalveolar washing") is a medical procedure in which a bronchoscope is passed through the mouth or nose into the lungs and fluid is squirted into a small part of the lung and then collected for examination.
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Calciphylaxis
Calciphylaxis, also known as calcific uremic arteriolopathy (CUA), is a rare painful syndrome of calcification of the small blood vessels located within the fatty tissue and deeper layers of the skin, blood clots, and the death of skin cells due to too little blood flow.
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Calcitriol
Calcitriol (INN), also called 1,25-dihydroxycholecalciferol, or 1alpha,25-dihydroxyvitamin D3, 1,25-dihydroxyvitamin D3 and other variants, is the hormonally active metabolite of vitamin D which has three hydroxyl groups.
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Cancer
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.
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Carbohydrate
A carbohydrate is a biomolecule consisting of carbon (C), hydrogen (H) and oxygen (O) atoms, usually with a hydrogen–oxygen atom ratio of 2:1 (as in water); in other words, with the empirical formula (where m may be different from n).
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Cell (biology)
The cell (from Latin cella, meaning "small room") is the basic structural, functional, and biological unit of all known living organisms.
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Cell adhesion
Cell adhesion is the process by which cells interact and attach to neighbouring cells through specialised molecules of the cell surface.
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Cell adhesion molecule
Cell adhesion molecules (CAMs) are proteins located on the cell surface involved in binding with other cells or with the extracellular matrix (ECM) in the process called cell adhesion.
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Chemotaxis
Chemotaxis (from chemo- + taxis) is the movement of an organism in response to a chemical stimulus.
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Chondrocyte
Chondrocytes (from Greek χόνδρος, chondros.
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Chromosome 4
Chromosome 4 is one of the 23 pairs of chromosomes in humans.
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Colorectal cancer
Colorectal cancer (CRC), also known as bowel cancer and colon cancer, is the development of cancer from the colon or rectum (parts of the large intestine).
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Crohn's disease
Crohn's disease is a type of inflammatory bowel disease (IBD) that may affect any part of the gastrointestinal tract from mouth to anus.
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Cytokine
Cytokines are a broad and loose category of small proteins (~5–20 kDa) that are important in cell signaling.
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Decidua
The decidua is the uterine lining (endometrium) during a pregnancy, which forms the maternal part of the placenta.
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Deficiency (medicine)
In medicine, a deficiency is a lack or shortage of a functional entity, by less than normal or necessary supply or function.
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Degranulation
Degranulation is a cellular process that releases antimicrobial cytotoxic or other molecules from secretory vesicles called granules found inside some cells.
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Dendritic cell
Dendritic cells (DCs) are antigen-presenting cells (also known as accessory cells) of the mammalian immune system.
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Duchenne muscular dystrophy
Duchenne muscular dystrophy (DMD) is a severe type of muscular dystrophy.
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Ear
The ear is the organ of hearing and, in mammals, balance.
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Ectopic calcification
Ectopic calcification is a pathologic deposition of calcium salts in tissues or bone growth in soft tissues.
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Endothelium
Endothelium refers to cells that line the interior surface of blood vessels and lymphatic vessels, forming an interface between circulating blood or lymph in the lumen and the rest of the vessel wall.
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Epitope
An epitope, also known as antigenic determinant, is the part of an antigen that is recognized by the immune system, specifically by antibodies, B cells, or T cells.
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Exon
An exon is any part of a gene that will encode a part of the final mature RNA produced by that gene after introns have been removed by RNA splicing.
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Extracellular matrix
In biology, the extracellular matrix (ECM) is a collection of extracellular molecules secreted by support cells that provides structural and biochemical support to the surrounding cells.
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Fibroblast
A fibroblast is a type of biological cell that synthesizes the extracellular matrix and collagen, the structural framework (stroma) for animal tissues, and plays a critical role in wound healing.
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Gene expression
Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product.
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Glomerulonephritis
Glomerulonephritis (GN), also known as glomerular nephritis, is a term used to refer to several kidney diseases (usually affecting both kidneys).
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Glutamic acid
Glutamic acid (symbol Glu or E) is an α-amino acid with formula.
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Glycoprotein
Glycoproteins are proteins that contain oligosaccharide chains (glycans) covalently attached to amino acid side-chains.
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Golgi apparatus
The Golgi apparatus, also known as the Golgi complex, Golgi body, or simply the Golgi, is an organelle found in most eukaryotic cells.
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Hydroxylapatite
Hydroxylapatite, also called hydroxyapatite (HA), is a naturally occurring mineral form of calcium apatite with the formula Ca5(PO4)3(OH), but is usually written Ca10(PO4)6(OH)2 to denote that the crystal unit cell comprises two entities.
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In vitro
In vitro (meaning: in the glass) studies are performed with microorganisms, cells, or biological molecules outside their normal biological context.
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Inflammatory bowel disease
Inflammatory bowel disease (IBD) is a group of inflammatory conditions of the colon and small intestine.
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Interferon gamma
Interferon gamma (IFNγ) is a dimerized soluble cytokine that is the only member of the type II class of interferons.
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Interleukin 12
Interleukin 12 (IL-12) is an interleukin that is naturally produced by dendritic cells, macrophages, neutrophils, and human B-lymphoblastoid cells (NC-37) in response to antigenic stimulation.
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Interleukin 17
Interleukin 17A (IL-17 or IL-17A) is a pro-inflammatory cytokine.
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Interstitial nephritis
Interstitial nephritis (or tubulo-interstitial nephritis) is a form of nephritis affecting the interstitium of the kidneys surrounding the tubules, i.e., is inflammation of the spaces between renal tubules.
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Kidney
The kidneys are two bean-shaped organs present in left and right sides of the body in vertebrates.
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Kidney stone disease
Kidney stone disease, also known as urolithiasis, is when a solid piece of material (kidney stone) occurs in the urinary tract.
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Locus (genetics)
A locus (plural loci) in genetics is a fixed position on a chromosome, like the position of a gene or a marker (genetic marker).
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Lung cancer
Lung cancer, also known as lung carcinoma, is a malignant lung tumor characterized by uncontrolled cell growth in tissues of the lung.
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Macrophage
Macrophages (big eaters, from Greek μακρός (makrós).
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Mast cell
A mast cell (also known as a mastocyte or a labrocyte) is a type of white blood cell.
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Melanoma
Melanoma, also known as malignant melanoma, is a type of cancer that develops from the pigment-containing cells known as melanocytes.
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Multiple sclerosis
Multiple sclerosis (MS) is a demyelinating disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged.
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Myocyte
A myocyte (also known as a muscle cell) is the type of cell found in muscle tissue.
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Neutrophil
Neutrophils (also known as neutrocytes) are the most abundant type of granulocytes and the most abundant (40% to 70%) type of white blood cells in most mammals.
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Odontoblast
In vertebrates, an odontoblast is a cell of neural crest origin that is part of the outer surface of the dental pulp, and whose biological function is dentinogenesis, which is the formation of dentin, the substance beneath the tooth enamel on the crown and the cementum on the root.
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Organic compound
In chemistry, an organic compound is generally any chemical compound that contains carbon.
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Osteoblast
Osteoblasts (from the Greek combining forms for "bone", ὀστέο-, osteo- and βλαστάνω, blastanō "germinate") are cells with a single nucleus that synthesize bone.
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Osteocalcin
Osteocalcin, also known as bone gamma-carboxyglutamic acid-containing protein (BGLAP), is a noncollagenous protein hormone found in bone and dentin.
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Osteoclast
An osteoclast is a type of bone cell that breaks down bone tissue.
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Osteocyte
An osteocyte, a star-shaped type of bone cell, is the most commonly found cell in mature bone tissue, and can live as long as the organism itself.
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Osteonectin
Osteonectin (ON) also known as secreted protein acidic and rich in cysteine (SPARC) or basement-membrane protein 40 (BM-40) is a protein that in humans is encoded by the SPARC gene.
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Osteoporosis
Osteoporosis is a disease where increased bone weakness increases the risk of a broken bone.
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Osteoprotegerin
Osteoprotegerin (OPG), also known as osteoclastogenesis inhibitory factor (OCIF) or tumour necrosis factor receptor superfamily member 11B (TNFRSF11B), is a cytokine receptor of the tumour necrosis factor (TNF) receptor superfamily encoded by the TNFRSF11B gene.
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Ovarian cancer
Ovarian cancer is a cancer that forms in or on an ovary.
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Oxalate
Oxalate (IUPAC: ethanedioate) is the dianion with the formula, also written.
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PHEX
Phosphate-regulating neutral endopeptidase, X-linked also known as phosphate-regulating gene with homologies to endopeptidases on the X chromosome or metalloendopeptidase homolog PEX is an enzyme that in humans is encoded by the PHEX gene.
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Phosphorylation
In chemistry, phosphorylation of a molecule is the attachment of a phosphoryl group.
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Phosphoserine
Phosphoserine (abbreviated as SEP or J) is an ester of serine and phosphoric acid.
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Placenta
The placenta is an organ that connects the developing fetus to the uterine wall to allow nutrient uptake, thermo-regulation, waste elimination, and gas exchange via the mother's blood supply; to fight against internal infection; and to produce hormones which support pregnancy.
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Pleural cavity
The pleural cavity is the thin fluid-filled space between the two pulmonary pleurae (known as visceral and parietal) of each lung.
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Post-translational modification
Post-translational modification (PTM) refers to the covalent and generally enzymatic modification of proteins following protein biosynthesis.
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Protein
Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.
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Rheumatoid arthritis
Rheumatoid arthritis (RA) is a long-term autoimmune disorder that primarily affects joints.
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Sialic acid
Sialic acid is a generic term for the N- or O-substituted derivatives of neuraminic acid, a monosaccharide with a nine-carbon backbone.
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SIBLING proteins
The family of non-collagenous proteins known as SIBLING proteins, standing for small integrin-binding ligand, N-linked glycoprotein, are components of the extracellular matrix of bone and dentin.
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Signal transduction
Signal transduction is the process by which a chemical or physical signal is transmitted through a cell as a series of molecular events, most commonly protein phosphorylation catalyzed by protein kinases, which ultimately results in a cellular response.
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Skeletal muscle
Skeletal muscle is one of three major muscle types, the others being cardiac muscle and smooth muscle.
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Smooth muscle tissue
Smooth muscle is an involuntary non-striated muscle.
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Sputum
Sputum is mucus and is the name used for the coughed-up material (phlegm) from the lower airways (trachea and bronchi).
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Stomach cancer
Stomach cancer, also known as gastric cancer, is cancer developing from the lining of the stomach.
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T cell
A T cell, or T lymphocyte, is a type of lymphocyte (a subtype of white blood cell) that plays a central role in cell-mediated immunity.
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Thrombin
Thrombin (fibrinogenase, thrombase, thrombofort, topical, thrombin-C, tropostasin, activated blood-coagulation factor II, blood-coagulation factor IIa, factor IIa, E thrombin, beta-thrombin, gamma-thrombin) is a serine protease, an enzyme that, in humans, is encoded by the F2 gene.
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Type I collagen
Type I collagen is the most abundant collagen of the human body which forms large, eosinophilic fibers known as collagen fibers.
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Ulcerative colitis
Ulcerative colitis (UC) is a long-term condition that results in inflammation and ulcers of the colon and rectum.
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Urine
Urine is a liquid by-product of metabolism in humans and in many animals.
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VDRE
Vitamin D response element (VDRE) is a DNA sequence that is found in the promoter region of vitamin D regulated genes.
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White blood cell
White blood cells (WBCs), also called leukocytes or leucocytes, are the cells of the immune system that are involved in protecting the body against both infectious disease and foreign invaders.
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Wound healing
Wound healing is an intricate process in which the skin repairs itself after injury.
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Redirects here:
BNSP, BSPI, Bnsp, Bspi, ETA-1, Eta-1, SPP1 (gene), Secreted phosphoprotein 1.
References
[1] https://en.wikipedia.org/wiki/Osteopontin
