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Buprenorphine

Index Buprenorphine

Buprenorphine, sold under the brand name Subutex among others, is an opioid used to treat opioid use disorder, acute pain, and chronic pain. [1]

Table of Contents

  1. 113 relations: Active metabolite, Adrenal insufficiency, Adverse drug reaction, Agonist, Agonist-antagonist, Alcohol (drug), Allergy, Alternative splicing, Benzodiazepine, Bile, Bile duct, Bioavailability, Biological activity, Biological half-life, Breastfeeding, Buccal administration, Buprenorphine-3-glucuronide, Buprenorphine/naloxone, Buprenorphine/samidorphan, Central sleep apnea, Chronic pain, Clinical trial, Cocaine dependence, Combination drug, Constipation, Controlled substance, Controlled Substances Act, CYP2C8, CYP3A4, Cytochrome P450, Diário Oficial da União, Drug Addiction Treatment Act, Drug-induced QT prolongation, Elimination (pharmacology), Enzyme, Equianalgesic, Euphoria, Excretion, Exon, First pass effect, Food and Drug Administration, Glucuronidation, Glucuronide, Health Canada, Heroin, Hydrochloride, Hypotension, Hypoventilation, IC50, Implant (medicine), ... Expand index (63 more) »

  2. Cat medications
  3. Delta-opioid receptor antagonists
  4. Dog medications
  5. Drugs developed by Schering-Plough
  6. Kappa-opioid receptor antagonists
  7. Nociceptin receptor agonists
  8. Nociceptin receptor antagonists
  9. Oripavines

Active metabolite

An active metabolite, or pharmacologically active metabolite is a biologically active metabolite of a xenobiotic substance, such as a drug or environmental chemical.

See Buprenorphine and Active metabolite

Adrenal insufficiency

Adrenal insufficiency is a condition in which the adrenal glands do not produce adequate amounts of steroid hormones.

See Buprenorphine and Adrenal insufficiency

Adverse drug reaction

An adverse drug reaction (ADR) is a harmful, unintended result caused by taking medication.

See Buprenorphine and Adverse drug reaction

Agonist

An agonist is a chemical that activates a receptor to produce a biological response.

See Buprenorphine and Agonist

Agonist-antagonist

In pharmacology the term agonist-antagonist or mixed agonist/antagonist is used to refer to a drug which under some conditions behaves as an agonist (a substance that fully activates the receptor that it binds to) while under other conditions, behaves as an antagonist (a substance that binds to a receptor but does not activate and can block the activity of other agonists).

See Buprenorphine and Agonist-antagonist

Alcohol (drug)

Alcohol, sometimes referred to by the chemical name ethanol, is one of the most widely used and abused psychoactive drugs in the world and falls under the depressant category. Buprenorphine and Alcohol (drug) are Euphoriants.

See Buprenorphine and Alcohol (drug)

Allergy

Allergies, also known as allergic diseases, are various conditions caused by hypersensitivity of the immune system to typically harmless substances in the environment.

See Buprenorphine and Allergy

Alternative splicing

Alternative splicing, or alternative RNA splicing, or differential splicing, is an alternative splicing process during gene expression that allows a single gene to produce different splice variants.

See Buprenorphine and Alternative splicing

Benzodiazepine

Benzodiazepines (BZD, BDZ, BZs), colloquially called "benzos", are a class of depressant drugs whose core chemical structure is the fusion of a benzene ring and a diazepine ring.

See Buprenorphine and Benzodiazepine

Bile

Bile (from Latin bilis), or gall, is a yellow-green fluid produced by the liver of most vertebrates that aids the digestion of lipids in the small intestine.

See Buprenorphine and Bile

Bile duct

A bile duct is any of a number of long tube-like structures that carry bile, and is present in most vertebrates.

See Buprenorphine and Bile duct

Bioavailability

In pharmacology, bioavailability is a subcategory of absorption and is the fraction (%) of an administered drug that reaches the systemic circulation.

See Buprenorphine and Bioavailability

Biological activity

In pharmacology, biological activity or pharmacological activity describes the beneficial or adverse effects of a drug on living matter.

See Buprenorphine and Biological activity

Biological half-life

Biological half-life (elimination half-life, pharmacological half-life) is the time taken for concentration of a biological substance (such as a medication) to decrease from its maximum concentration (Cmax) to half of Cmax in the blood plasma.

See Buprenorphine and Biological half-life

Breastfeeding

Breastfeeding, variously known as chestfeeding or nursing, is the process where breast milk is fed to a child.

See Buprenorphine and Breastfeeding

Buccal administration

Buccal administration is a topical route of administration by which drugs held or applied in the buccal area (in the cheek) diffuse through the oral mucosa (tissues which line the mouth) and enter directly into the bloodstream.

See Buprenorphine and Buccal administration

Buprenorphine-3-glucuronide

Buprenorphine-3-glucuronide (B3G) is a major active metabolite of the opioid modulator buprenorphine. Buprenorphine and buprenorphine-3-glucuronide are Oripavines and Tertiary alcohols.

See Buprenorphine and Buprenorphine-3-glucuronide

Buprenorphine/naloxone

Buprenorphine/naloxone, sold under the brand name Suboxone among others, is a fixed-dose combination medication that includes buprenorphine and naloxone. Buprenorphine and Buprenorphine/naloxone are drug rehabilitation, drugs developed by Merck & Co., drugs developed by Schering-Plough, kappa-opioid receptor antagonists, mu-opioid receptor agonists, Oripavines and Semisynthetic opioids.

See Buprenorphine and Buprenorphine/naloxone

Buprenorphine/samidorphan

Buprenorphine/samidorphan (developmental code name ALKS-5461) is a combination formulation of buprenorphine and samidorphan which is under development as an add on to antidepressants in treatment-resistant depression (TRD). Buprenorphine and Buprenorphine/samidorphan are Delta-opioid receptor antagonists, drug rehabilitation, kappa-opioid receptor antagonists, nociceptin receptor agonists, nociceptin receptor antagonists and Semisynthetic opioids.

See Buprenorphine and Buprenorphine/samidorphan

Central sleep apnea

Central sleep apnea (CSA) or central sleep apnea syndrome (CSAS) is a sleep-related disorder in which the effort to breathe is diminished or absent, typically for 10 to 30 seconds either intermittently or in cycles, and is usually associated with a reduction in blood oxygen saturation.

See Buprenorphine and Central sleep apnea

Chronic pain

Chronic pain or chronic pain syndrome is a type of pain that is also known by other titles such as gradual burning pain, electrical pain, throbbing pain, and nauseating pain.

See Buprenorphine and Chronic pain

Clinical trial

Clinical trials are prospective biomedical or behavioral research studies on human participants designed to answer specific questions about biomedical or behavioral interventions, including new treatments (such as novel vaccines, drugs, dietary choices, dietary supplements, and medical devices) and known interventions that warrant further study and comparison.

See Buprenorphine and Clinical trial

Cocaine dependence

Cocaine dependence is a neurological disorder that is characterized by withdrawal symptoms upon cessation from cocaine use.

See Buprenorphine and Cocaine dependence

Combination drug

A combination drug or a fixed-dose combination (FDC) is a medicine that includes two or more active ingredients combined in a single dosage form.

See Buprenorphine and Combination drug

Constipation

Constipation is a bowel dysfunction that makes bowel movements infrequent or hard to pass.

See Buprenorphine and Constipation

Controlled substance

A controlled substance is generally a drug or chemical whose manufacture, possession and use is regulated by a government, such as illicitly used drugs or prescription medications that are designated by law.

See Buprenorphine and Controlled substance

Controlled Substances Act

The Controlled Substances Act (CSA) is the statute establishing federal U.S. drug policy under which the manufacture, importation, possession, use, and distribution of certain substances is regulated.

See Buprenorphine and Controlled Substances Act

CYP2C8

Cytochrome P4502C8 (CYP2C8) is a member of the cytochrome P450 mixed-function oxidase system involved in the metabolism of xenobiotics in the body.

See Buprenorphine and CYP2C8

CYP3A4

Cytochrome P450 3A4 (abbreviated CYP3A4) is an important enzyme in the body, mainly found in the liver and in the intestine, which in humans is encoded by CYP3A4 gene.

See Buprenorphine and CYP3A4

Cytochrome P450

Cytochromes P450 (P450s or CYPs) are a superfamily of enzymes containing heme as a cofactor that mostly, but not exclusively, function as monooxygenases.

See Buprenorphine and Cytochrome P450

Diário Oficial da União

The Diário Oficial da União (literally Official Diary of the Union), abbreviated DOU, is the official journal of the federal government of Brazil.

See Buprenorphine and Diário Oficial da União

Drug Addiction Treatment Act

The Drug Addiction Treatment Act of 2000 (DATA 2000), Title XXXV, Section 3502 of the Children's Health Act, permits physicians who meet certain qualifications to treat opioid addiction with Schedule III, IV, and V narcotic medications that have been specifically approved by the Food and Drug Administration for that indication.

See Buprenorphine and Drug Addiction Treatment Act

Drug-induced QT prolongation

QT prolongation is a measure of delayed ventricular repolarisation, which means the heart muscle takes longer than normal to recharge between beats.

See Buprenorphine and Drug-induced QT prolongation

Elimination (pharmacology)

In pharmacology, the elimination or excretion of a drug is understood to be any one of a number of processes by which a drug is eliminated (that is, cleared and excreted) from an organism either in an unaltered form (unbound molecules) or modified as a metabolite.

See Buprenorphine and Elimination (pharmacology)

Enzyme

Enzymes are proteins that act as biological catalysts by accelerating chemical reactions.

See Buprenorphine and Enzyme

Equianalgesic

An equianalgesic chart is a conversion chart that lists equivalent doses of analgesics (drugs used to relieve pain).

See Buprenorphine and Equianalgesic

Euphoria

Euphoria is the experience (or affect) of pleasure or excitement and intense feelings of well-being and happiness. Buprenorphine and Euphoria are Euphoriants.

See Buprenorphine and Euphoria

Excretion

Excretion is elimination of metabolic waste, which is an essential process in all organisms.

See Buprenorphine and Excretion

Exon

An exon is any part of a gene that will form a part of the final mature RNA produced by that gene after introns have been removed by RNA splicing.

See Buprenorphine and Exon

First pass effect

The first pass effect (also known as first-pass metabolism or presystemic metabolism) is a phenomenon of drug metabolism at a specific location in the body which leads to a reduction in the concentration of the active drug before it reaches the site of action or systemic circulation.

See Buprenorphine and First pass effect

Food and Drug Administration

The United States Food and Drug Administration (FDA or US FDA) is a federal agency of the Department of Health and Human Services.

See Buprenorphine and Food and Drug Administration

Glucuronidation

Glucuronidation is often involved in drug metabolism of substances such as drugs, pollutants, bilirubin, androgens, estrogens, mineralocorticoids, glucocorticoids, fatty acid derivatives, retinoids, and bile acids.

See Buprenorphine and Glucuronidation

Glucuronide

A glucuronide, also known as glucuronoside, is any substance produced by linking glucuronic acid to another substance via a glycosidic bond.

See Buprenorphine and Glucuronide

Health Canada

Health Canada (HC; Santé Canada, SC)Health Canada is the applied title under the Federal Identity Program; the legal title is Department of Health.

See Buprenorphine and Health Canada

Heroin

Heroin, also known as diacetylmorphine and diamorphine among other names, is a morphinan opioid substance synthesized from the dried latex of the Papaver somniferum plant; it is mainly used as a recreational drug for its euphoric effects. Buprenorphine and Heroin are Euphoriants, mu-opioid receptor agonists and Semisynthetic opioids.

See Buprenorphine and Heroin

Hydrochloride

In chemistry, a hydrochloride is an acid salt resulting, or regarded as resulting, from the reaction of hydrochloric acid with an organic base (e.g. an amine).

See Buprenorphine and Hydrochloride

Hypotension

Hypotension, also known as low blood pressure, is a cardiovascular condition characterized by abnormally reduced blood pressure.

See Buprenorphine and Hypotension

Hypoventilation

Hypoventilation (also known as respiratory depression) occurs when ventilation is inadequate (hypo meaning "below") to perform needed respiratory gas exchange.

See Buprenorphine and Hypoventilation

IC50

Half maximal inhibitory concentration (IC50) is a measure of the potency of a substance in inhibiting a specific biological or biochemical function.

See Buprenorphine and IC50

Implant (medicine)

An implant is a medical device manufactured to replace a missing biological structure, support a damaged biological structure, or enhance an existing biological structure.

See Buprenorphine and Implant (medicine)

Injection (medicine)

An injection (often and usually referred to as a "shot" in US English, a "jab" in UK English, or a "jag" in Scottish English and Scots) is the act of administering a liquid, especially a drug, into a person's body using a needle (usually a hypodermic needle) and a syringe.

See Buprenorphine and Injection (medicine)

Intramuscular injection

Intramuscular injection, often abbreviated IM, is the injection of a substance into a muscle.

See Buprenorphine and Intramuscular injection

Intravenous therapy

Intravenous therapy (abbreviated as IV therapy) is a medical technique that administers fluids, medications and nutrients directly into a person's vein.

See Buprenorphine and Intravenous therapy

Isozyme

In biochemistry, isozymes (also known as isoenzymes or more generally as multiple forms of enzymes) are enzymes that differ in amino acid sequence but catalyze the same chemical reaction.

See Buprenorphine and Isozyme

Μ-opioid receptor

The μ-opioid receptors (MOR) are a class of opioid receptors with a high affinity for enkephalins and beta-endorphin, but a low affinity for dynorphins.

See Buprenorphine and Μ-opioid receptor

Kidney

In humans, the kidneys are two reddish-brown bean-shaped blood-filtering organs that are a multilobar, multipapillary form of mammalian kidneys, usually without signs of external lobulation.

See Buprenorphine and Kidney

Kidney failure

Kidney failure, also known as end-stage renal disease (ESRD), is a medical condition in which the kidneys can no longer adequately filter waste products from the blood, functioning at less than 15% of normal levels. Kidney failure is classified as either acute kidney failure, which develops rapidly and may resolve; and chronic kidney failure, which develops slowly and can often be irreversible.

See Buprenorphine and Kidney failure

Liver

The liver is a major metabolic organ exclusively found in vertebrate animals, which performs many essential biological functions such as detoxification of the organism, and the synthesis of proteins and various other biochemicals necessary for digestion and growth.

See Buprenorphine and Liver

Local anesthetic

A local anesthetic (LA) is a medication that causes absence of all sensation (including pain) in a specific body part without loss of consciousness, providing local anesthesia, as opposed to a general anesthetic, which eliminates all sensation in the entire body and causes unconsciousness.

See Buprenorphine and Local anesthetic

Medical imaging

Medical imaging is the technique and process of imaging the interior of a body for clinical analysis and medical intervention, as well as visual representation of the function of some organs or tissues (physiology).

See Buprenorphine and Medical imaging

Metabolism

Metabolism (from μεταβολή metabolē, "change") is the set of life-sustaining chemical reactions in organisms.

See Buprenorphine and Metabolism

Methadone

Methadone, sold under the brand names Dolophine and Methadose among others, is a synthetic opioid agonist used for chronic pain and also for opioid use disorder. Buprenorphine and Methadone are CYP2D6 inhibitors, drug rehabilitation, Euphoriants and mu-opioid receptor agonists.

See Buprenorphine and Methadone

Microdosing

Microdosing, or micro-dosing, involves the administration of sub-therapeutic doses of drugs to study their effects in humans, aiming to gather preliminary data on safety, pharmacokinetics, and potential therapeutic benefits without producing significant physiological effects.

See Buprenorphine and Microdosing

Miosis

Miosis, or myosis, is excessive constriction of the pupil.

See Buprenorphine and Miosis

Naloxone

Naloxone is an opioid antagonist: a medication used to reverse or reduce the effects of opioids. Buprenorphine and Naloxone are kappa-opioid receptor antagonists and Tertiary alcohols.

See Buprenorphine and Naloxone

Nasal administration

Nasal administration, popularly known as snorting, is a route of administration in which drugs are insufflated through the nose.

See Buprenorphine and Nasal administration

Neonatal withdrawal

Neonatal withdrawal or neonatal abstinence syndrome (NAS) or neonatal opioid withdrawal syndrome (NOWS) is a withdrawal syndrome of infants, caused by the cessation of the administration of licit or illicit drugs.

See Buprenorphine and Neonatal withdrawal

Netherlands

The Netherlands, informally Holland, is a country located in Northwestern Europe with overseas territories in the Caribbean.

See Buprenorphine and Netherlands

Nociceptin receptor

The nociceptin opioid peptide receptor (NOP), also known as the nociceptin/orphanin FQ (N/OFQ) receptor or kappa-type 3 opioid receptor, is a protein that in humans is encoded by the OPRL1 (opioid receptor-like 1) gene.

See Buprenorphine and Nociceptin receptor

Norbuprenorphine

Norbuprenorphine is a major active metabolite of the opioid modulator buprenorphine. Buprenorphine and Norbuprenorphine are ethers, mu-opioid receptor agonists, nociceptin receptor agonists, Phenols and Tertiary alcohols.

See Buprenorphine and Norbuprenorphine

Norbuprenorphine-3-glucuronide

Norbuprenorphine-3-glucuronide (N3G) is a major active metabolite of the opioid modulator buprenorphine. Buprenorphine and Norbuprenorphine-3-glucuronide are ethers, Phenols and Tertiary alcohols.

See Buprenorphine and Norbuprenorphine-3-glucuronide

Opioid

Opioids are a class of drugs that derive from, or mimic, natural substances found in the opium poppy plant.

See Buprenorphine and Opioid

Opioid agonist therapy

Opioid agonist therapy (OAT) is a treatment in which prescribed opioid agonists are given to patients who live with Opioid use disorder (OUD). Buprenorphine and opioid agonist therapy are mu-opioid receptor agonists.

See Buprenorphine and Opioid agonist therapy

Opioid modulator

An opioid modulator (or opioid receptor modulator) is a drug which has mixed agonist and antagonist actions at different opioid receptors and thus cannot clearly be described as either an opioid agonist or antagonist.

See Buprenorphine and Opioid modulator

Opioid receptor

Opioid receptors are a group of inhibitory G protein-coupled receptors with opioids as ligands.

See Buprenorphine and Opioid receptor

Opioid use disorder

Opioid use disorder (OUD) is a substance use disorder characterized by cravings for opioids, continued use despite physical and/or psychological deterioration, increased tolerance with use, and withdrawal symptoms after discontinuing opioids.

See Buprenorphine and Opioid use disorder

Opioid withdrawal

Opioid withdrawal is a set of symptoms (a syndrome) arising from the sudden withdrawal or reduction of opioids where previous usage has been heavy and prolonged. Buprenorphine and opioid withdrawal are drug rehabilitation.

See Buprenorphine and Opioid withdrawal

Opium Law

The Opium Law (Opiumwet in Dutch) is the section of the Dutch law which covers nearly all psychotropic drugs.

See Buprenorphine and Opium Law

Oral administration

| name.

See Buprenorphine and Oral administration

Orthostatic hypotension

Orthostatic hypotension, also known as postural hypotension, is a medical condition wherein a person's blood pressure drops when standing up or sitting down.

See Buprenorphine and Orthostatic hypotension

P-glycoprotein

P-glycoprotein 1 (permeability glycoprotein, abbreviated as P-gp or Pgp) also known as multidrug resistance protein 1 (MDR1) or ATP-binding cassette sub-family B member 1 (ABCB1) or cluster of differentiation 243 (CD243) is an important protein of the cell membrane that pumps many foreign substances out of cells.

See Buprenorphine and P-glycoprotein

Pain

Pain is a distressing feeling often caused by intense or damaging stimuli.

See Buprenorphine and Pain

Pain management

Pain management is an aspect of medicine and health care involving relief of pain (pain relief, analgesia, pain control) in various dimensions, from acute and simple to chronic and challenging.

See Buprenorphine and Pain management

Partial agonist

In pharmacology, partial agonists are drugs that bind to and activate a given receptor, but have only partial efficacy at the receptor relative to a full agonist.

See Buprenorphine and Partial agonist

Perioperative

The perioperative period is the period of a patient's surgical procedure.

See Buprenorphine and Perioperative

Physical dependence

Physical dependence is a physical condition caused by chronic use of a tolerance-forming drug, in which abrupt or gradual drug withdrawal causes unpleasant physical symptoms.

See Buprenorphine and Physical dependence

Positron emission tomography

Positron emission tomography (PET) is a functional imaging technique that uses radioactive substances known as radiotracers to visualize and measure changes in metabolic processes, and in other physiological activities including blood flow, regional chemical composition, and absorption.

See Buprenorphine and Positron emission tomography

Pregnancy

Pregnancy is the time during which one or more offspring develops (gestates) inside a woman's uterus (womb).

See Buprenorphine and Pregnancy

Psychological dependence

Psychological dependence is a cognitive disorder that involves emotional–motivational withdrawal symptoms – such as anxiety or anhedonia – upon cessation of prolonged drug abuse or certain repetitive behaviors.

See Buprenorphine and Psychological dependence

Receptor antagonist

A receptor antagonist is a type of receptor ligand or drug that blocks or dampens a biological response by binding to and blocking a receptor rather than activating it like an agonist.

See Buprenorphine and Receptor antagonist

Reckitt

Reckitt Benckiser is a British-Dutch multinational consumer goods company headquartered in Slough, United Kingdom, and Hoofddorp, Netherlands.

See Buprenorphine and Reckitt

Rectal administration

Rectal administration (colloquially known as boofing or plugging) uses the rectum as a route of administration for medication and other fluids, which are absorbed by the rectum's blood vessels,The rectum has numerous blood vessels available to absorb drugs: upwards 2/3rds of the dose bypasses first-pass metabolism through systemic distribution and the rest is taken through the liver and metabolized via the hepatic portal system.

See Buprenorphine and Rectal administration

Samidorphan

Samidorphan (developmental code names ALKS-33, RDC-0313) is an opioid antagonist that in the form of olanzapine/samidorphan (brand name Lybalvi) is used in the treatment of schizophrenia and bipolar disorder.

See Buprenorphine and Samidorphan

Seizure

A seizure is a period of symptoms due to abnormally excessive or synchronous neuronal activity in the brain.

See Buprenorphine and Seizure

Sigma receptor

Sigma receptors (σ-receptors) are protein receptors that bind ligands such as 4-PPBP (4-phenyl-1-(4-phenylbutyl) piperidine), SA 4503 (cutamesine), ditolylguanidine, dimethyltryptamine, and siramesine.

See Buprenorphine and Sigma receptor

Sigma-1 receptor

The sigma-1 receptor (σ1R), one of two sigma receptor subtypes, is a chaperone protein at the endoplasmic reticulum (ER) that modulates calcium signaling through the IP3 receptor.

See Buprenorphine and Sigma-1 receptor

Sigma-2 receptor

The sigma-2 receptor (σ2R) is a sigma receptor subtype that has attracted attention due to its involvement in diseases such as neurological diseases, neurodegenerative, neuro-ophthalmic and cancer.

See Buprenorphine and Sigma-2 receptor

Subcutaneous administration

Subcutaneous administration is the insertion of medications beneath the skin either by injection or infusion.

See Buprenorphine and Subcutaneous administration

Sublingual administration

Sublingual (abbreviated SL), from the Latin for "under the tongue", refers to the pharmacological route of administration by which substances diffuse into the blood through tissues under the tongue.

See Buprenorphine and Sublingual administration

The New Republic

The New Republic is an American publisher focused on domestic politics, news, culture, and the arts, with ten magazines a year and a daily online platform.

See Buprenorphine and The New Republic

Thebaine

Thebaine (paramorphine), also known as codeine methyl enol ether, is an opiate alkaloid, its name coming from the Greek Θῆβαι, Thēbai (Thebes), an ancient city in Upper Egypt. Buprenorphine and Thebaine are ethers.

See Buprenorphine and Thebaine

Therapeutic Goods Administration

The Therapeutic Goods Administration (TGA) is the medicine and therapeutic regulatory agency of the Australian Government.

See Buprenorphine and Therapeutic Goods Administration

Toll-like receptor 4

Toll-like receptor 4 (TLR4), also designated as CD284 (cluster of differentiation 284), is a key activator of the innate immune response and plays a central role in the fight against bacterial infections.

See Buprenorphine and Toll-like receptor 4

Transdermal

Transdermal is a route of administration wherein active ingredients are delivered across the skin for systemic distribution.

See Buprenorphine and Transdermal

Transdermal patch

A transdermal patch is a medicated adhesive patch that is placed on the skin to deliver a specific dose of medication through the skin and into the bloodstream.

See Buprenorphine and Transdermal patch

Treatment-resistant depression

Treatment-resistant depression (TRD) is a form of major depressive disorder (MDD) in which an affected person does not respond adequately to a course of appropriate antidepressant medication.

See Buprenorphine and Treatment-resistant depression

UDP glucuronosyltransferase 1 family, polypeptide A1

UDP-glucuronosyltransferase 1-1 also known as UGT-1A is an enzyme that in humans is encoded by the UGT1A1 gene.

See Buprenorphine and UDP glucuronosyltransferase 1 family, polypeptide A1

UGT1A3

UDP-glucuronosyltransferase 1-3 is an enzyme that in humans is encoded by the UGT1A3 gene.

See Buprenorphine and UGT1A3

UGT2B7

UGT2B7 (UDP-Glucuronosyltransferase-2B7) is a phase II metabolism isoenzyme found to be active in the liver, kidneys, epithelial cells of the lower gastrointestinal tract and also has been reported in the brain.

See Buprenorphine and UGT2B7

Urinary retention

Urinary retention is an inability to completely empty the bladder.

See Buprenorphine and Urinary retention

Voltage-gated sodium channel

Voltage-gated sodium channels (VGSCs), also known as voltage-dependent sodium channels (VDSCs), are a group of voltage-gated ion channels found in the membrane of excitable cells (e.g., muscle, glial cells, neurons, etc.) with a permeability to the sodium ion Na+.

See Buprenorphine and Voltage-gated sodium channel

WHO Model List of Essential Medicines

The WHO Model List of Essential Medicines (aka Essential Medicines List or EML), published by the World Health Organization (WHO), contains the medications considered to be most effective and safe to meet the most important needs in a health system.

See Buprenorphine and WHO Model List of Essential Medicines

Wired (magazine)

Wired (stylized in all caps) is a monthly American magazine, published in print and online editions, that focuses on how emerging technologies affect culture, the economy, and politics.

See Buprenorphine and Wired (magazine)

See also

Cat medications

Delta-opioid receptor antagonists

Dog medications

Drugs developed by Schering-Plough

Kappa-opioid receptor antagonists

Nociceptin receptor agonists

Nociceptin receptor antagonists

Oripavines

References

[1] https://en.wikipedia.org/wiki/Buprenorphine

Also known as ATC code N02AE01, ATC code N07BC01, ATCvet code QN02AE01, ATCvet code QN07BC01, Belbuca, Brixadi, Bupe, Bupernorphine, Bupomorphine, Bupredermal, Buprel, Buprenex, Buprenorphine Hydrochloride, Buprinex, Bupronorphine, Butrans, Buvidal, C29H41N1O4, C29H41NO4, Norspan, Probuphine, Sixmo, Sublocade, Subutex, Temgesic, Transtec, Vetergesic, Vetergesic multidose, Zorbium.

, Injection (medicine), Intramuscular injection, Intravenous therapy, Isozyme, Μ-opioid receptor, Kidney, Kidney failure, Liver, Local anesthetic, Medical imaging, Metabolism, Methadone, Microdosing, Miosis, Naloxone, Nasal administration, Neonatal withdrawal, Netherlands, Nociceptin receptor, Norbuprenorphine, Norbuprenorphine-3-glucuronide, Opioid, Opioid agonist therapy, Opioid modulator, Opioid receptor, Opioid use disorder, Opioid withdrawal, Opium Law, Oral administration, Orthostatic hypotension, P-glycoprotein, Pain, Pain management, Partial agonist, Perioperative, Physical dependence, Positron emission tomography, Pregnancy, Psychological dependence, Receptor antagonist, Reckitt, Rectal administration, Samidorphan, Seizure, Sigma receptor, Sigma-1 receptor, Sigma-2 receptor, Subcutaneous administration, Sublingual administration, The New Republic, Thebaine, Therapeutic Goods Administration, Toll-like receptor 4, Transdermal, Transdermal patch, Treatment-resistant depression, UDP glucuronosyltransferase 1 family, polypeptide A1, UGT1A3, UGT2B7, Urinary retention, Voltage-gated sodium channel, WHO Model List of Essential Medicines, Wired (magazine).