30 relations: Alanine, Amine, Amino acid, Capping enzyme, Carboxylic acid, Dehydration reaction, Endoplasmic reticulum, ER retention, Farnesyl pyrophosphate, G protein, Geranylgeranyl pyrophosphate, Glycine, Glycosylphosphatidylinositol, Lipid, Messenger RNA, N-terminus, Peptide, Post-translational modification, Prenylation, Prion, Protease, Protein, RNA polymerase II, RNA splicing, Secretion, Serine, Spliceosome, TopFIND, Transmembrane domain, Valine.
Alanine (symbol Ala or A) is an α-amino acid that is used in the biosynthesis of proteins.
In organic chemistry, amines are compounds and functional groups that contain a basic nitrogen atom with a lone pair.
Amino acids are organic compounds containing amine (-NH2) and carboxyl (-COOH) functional groups, along with a side chain (R group) specific to each amino acid.
A capping enzyme (CE) is an enzyme that catalyzes the attachment of the 5' cap to messenger RNA molecules that are in the process of being synthesized in the cell nucleus during the first stages of gene expression.
A carboxylic acid is an organic compound that contains a carboxyl group (C(.
In chemistry and the biological sciences, a dehydration reaction, also known as Zimmer's hydrogenesis, is a chemical reaction that involves the loss of a water molecule from the reacting molecule.
The endoplasmic reticulum (ER) is a type of organelle found in eukaryotic cells that forms an interconnected network of flattened, membrane-enclosed sacs or tube-like structures known as cisternae.
ER retention refers to proteins that are retained in the endoplasmic reticulum, or ER, after folding; these are known as ER resident proteins.
Farnesyl pyrophosphate (FPP), also known as farnesyl diphosphate (FDP), is an intermediate in both the mevalonate and non-mevalonate pathways used by organisms in the biosynthesis of terpenes, terpenoids, and sterols.
G proteins, also known as guanine nucleotide-binding proteins, are a family of proteins that act as molecular switches inside cells, and are involved in transmitting signals from a variety of stimuli outside a cell to its interior.
Geranylgeranyl pyrophosphate is an intermediate in the biosynthesis of diterpenes and diterpenoids.
Glycine (symbol Gly or G) is the amino acid that has a single hydrogen atom as its side chain.
Glycosylphosphatidylinositol, or glycophosphatidylinositol, or GPI in short, is a glycolipid that can be attached to the C-terminus of a protein during posttranslational modification.
In biology and biochemistry, a lipid is a biomolecule that is soluble in nonpolar solvents.
Messenger RNA (mRNA) is a large family of RNA molecules that convey genetic information from DNA to the ribosome, where they specify the amino acid sequence of the protein products of gene expression.
The N-terminus (also known as the amino-terminus, NH2-terminus, N-terminal end or amine-terminus) is the start of a protein or polypeptide referring to the free amine group (-NH2) located at the end of a polypeptide.
Peptides (from Gr.: πεπτός, peptós "digested"; derived from πέσσειν, péssein "to digest") are short chains of amino acid monomers linked by peptide (amide) bonds.
Post-translational modification (PTM) refers to the covalent and generally enzymatic modification of proteins following protein biosynthesis.
Prenylation (also known as isoprenylation or lipidation) is the addition of hydrophobic molecules to a protein or chemical compound.
Prions are misfolded proteins that are associated with several fatal neurodegenerative diseases in animals and humans.
A protease (also called a peptidase or proteinase) is an enzyme that performs proteolysis: protein catabolism by hydrolysis of peptide bonds.
Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.
RNA polymerase II (RNAP II and Pol II) is a multiprotein complex.
In molecular biology, splicing is the editing of the nascent precursor messenger RNA (pre-mRNA) transcript into a mature messenger RNA (mRNA).
Secretion is the movement of material from one point to another, e.g. secreted chemical substance from a cell or gland.
Serine (symbol Ser or S) is an ɑ-amino acid that is used in the biosynthesis of proteins.
A spliceosome is a large and complex molecular machine found primarily within the splicing speckles of the cell nucleus of eukaryotic cells.
TopFIND is the Termini oriented protein Function Inferred Database (TopFIND) is an integrated knowledgebase focused on protein termini, their formation by proteases and functional implications.
Transmembrane domain usually denotes a transmembrane segment of single alpha helix of a transmembrane protein.
Valine (symbol Val or V) is an α-amino acid that is used in the biosynthesis of proteins.
C terminal, C terminal end, C terminus, C-ter, C-term, C-terminal, C-terminal domain, C-terminal end, C-termini, COOH terminus, COOH-terminus, Carboxy terminus, Carboxy-Terminal Domain, Carboxy-terminal, Carboxy-terminus, Carboxyl terminal, Carboxyl terminus, Carboxyl-terminal, Carboxyl-terminus, Cooh terminus.