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13 relations: AMPA receptor, Anticonvulsant, Brain ischemia, Clinical trial, Derivative (chemistry), Drug, Epilepsy, IC50, International nonproprietary name, Neuropathic pain, Novartis, Quinoxalinedione, Receptor antagonist.
AMPA receptor
The α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (also known as AMPA receptor, AMPAR, or quisqualate receptor) is an ionotropic transmembrane receptor for glutamate that mediates fast synaptic transmission in the central nervous system (CNS).
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Anticonvulsant
Anticonvulsants (also commonly known as antiepileptic drugs or as antiseizure drugs) are a diverse group of pharmacological agents used in the treatment of epileptic seizures.
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Brain ischemia
Brain ischemia (a.k.a. cerebral ischemia, cerebrovascular ischemia) is a condition in which there is insufficient blood flow to the brain to meet metabolic demand.
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Clinical trial
Clinical trials are experiments or observations done in clinical research.
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Derivative (chemistry)
In chemistry, a derivative is a compound that is derived from a similar compound by a chemical reaction.
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Drug
A drug is any substance (other than food that provides nutritional support) that, when inhaled, injected, smoked, consumed, absorbed via a patch on the skin, or dissolved under the tongue causes a temporary physiological (and often psychological) change in the body.
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Epilepsy
Epilepsy is a group of neurological disorders characterized by epileptic seizures.
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IC50
The half maximal inhibitory concentration (IC50) is a measure of the potency of a substance in inhibiting a specific biological or biochemical function.
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International nonproprietary name
The International Nonproprietary Name (INN) is an official generic and non-proprietary name given to a pharmaceutical drug or an active ingredient.
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Neuropathic pain
Neuropathic pain is pain caused by damage or disease affecting the somatosensory nervous system.
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Novartis
Novartis International AG is a Swiss multinational pharmaceutical company based in Basel, Switzerland.
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Quinoxalinedione
Quinoxalinedione is an organic compound with the formula C6H4(NH)2(CO)2.
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Receptor antagonist
A receptor antagonist is a type of receptor ligand or drug that blocks or dampens a biological response by binding to and blocking a receptor rather than activating it like an agonist.
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