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66 relations: Actinomycosis, Allergy, Amneal Pharmaceuticals, Amyotrophic lateral sclerosis, Anemia, Antifolate, Australia, BBC News, Bone marrow suppression, Brazil, Canada, Dapsone, Dihydrofolate reductase, Dihydrofolic acid, Dihydropteroate synthase, DNA, Dyscrasia, Folate, Folate deficiency, Folinic acid, Forbes, Generic drug, Gertrude B. Elion, GlaxoSmithKline, Glossitis, Health system, Hexosaminidase, HIV/AIDS, Hydrogen bond, Imprimis Pharmaceuticals, Isosporiasis, Kidney, Leukopenia, Liver, Malaria, Martin Shkreli, Medicines for Malaria Venture, Methotrexate, Nobel Prize, Online pharmacy, Plasmodium falciparum, Plasmodium vivax, Pneumocystis jirovecii, Pneumocystis pneumonia, RNA, SOD1, Steric effects, Sulfadiazine, Sulfadoxine/pyrimethamine, Sulfamethoxazole, ..., Sulfonamide (medicine), Switzerland, Sydney Grammar School, Tay–Sachs disease, Tetrahydrofolic acid, The Guardian, The New York Times, The Washington Post, Thrombocytopenia, Toxoplasmic chorioretinitis, Toxoplasmosis, Trimethoprim, Turing Pharmaceuticals, University of Sydney, WHO Model List of Essential Medicines, 4-Aminobenzoic acid. Expand index (16 more) »
Actinomycosis
Actinomycosis is a rare infectious bacterial disease caused by Actinomyces species.
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Allergy
Allergies, also known as allergic diseases, are a number of conditions caused by hypersensitivity of the immune system to typically harmless substances in the environment.
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Amneal Pharmaceuticals
Amneal Pharmaceuticals, Inc. is a publicly traded generics and specialty pharmaceutical company.
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Amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS), also known as motor neurone disease (MND), and Lou Gehrig's disease, is a specific disease which causes the death of neurons controlling voluntary muscles.
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Anemia
Anemia is a decrease in the total amount of red blood cells (RBCs) or hemoglobin in the blood, or a lowered ability of the blood to carry oxygen.
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Antifolate
Antifolates are a class of antimetabolite medications that antagonise (that is, block) the actions of folic acid (vitamin B9).
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Australia
Australia, officially the Commonwealth of Australia, is a sovereign country comprising the mainland of the Australian continent, the island of Tasmania and numerous smaller islands.
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BBC News
BBC News is an operational business division of the British Broadcasting Corporation (BBC) responsible for the gathering and broadcasting of news and current affairs.
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Bone marrow suppression
Bone marrow suppression also known as myelotoxicity or myelosuppression, is the decrease in production of cells responsible for providing immunity (leukocytes), carrying oxygen (erythrocytes), and/or those responsible for normal blood clotting (thrombocytes).
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Brazil
Brazil (Brasil), officially the Federative Republic of Brazil (República Federativa do Brasil), is the largest country in both South America and Latin America.
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Canada
Canada is a country located in the northern part of North America.
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Dapsone
Dapsone, also known as diaminodiphenyl sulfone (DDS), is an antibiotic commonly used in combination with rifampicin and clofazimine for the treatment of leprosy.
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Dihydrofolate reductase
Dihydrofolate reductase, or DHFR, is an enzyme that reduces dihydrofolic acid to tetrahydrofolic acid, using NADPH as electron donor, which can be converted to the kinds of tetrahydrofolate cofactors used in 1-carbon transfer chemistry.
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Dihydrofolic acid
Dihydrofolic acid (conjugate base dihydrofolate) (DHF) is a folic acid (vitamin B9) derivative which is converted to tetrahydrofolic acid by dihydrofolate reductase.
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Dihydropteroate synthase
Dihydropteroate synthase is an enzyme classified under.
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DNA
Deoxyribonucleic acid (DNA) is a thread-like chain of nucleotides carrying the genetic instructions used in the growth, development, functioning and reproduction of all known living organisms and many viruses.
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Dyscrasia
Dyscrasia (or dyskrasia) is a concept from ancient Greek medicine, meaning bad mixture.
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Folate
Folate, distinct forms of which are known as folic acid, folacin, and vitamin B9, is one of the B vitamins.
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Folate deficiency
Folate deficiency is a low level of folic acid and derivatives in the body.
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Folinic acid
Folinic acid, also known as leucovorin, is a medication used to decrease the toxic effects of methotrexate and pyrimethamine.
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Forbes
Forbes is an American business magazine.
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Generic drug
A generic drug is a pharmaceutical drug that is equivalent to a brand-name product in dosage, strength, route of administration, quality, performance, and intended use, but does not carry the brand name.
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Gertrude B. Elion
Gertrude Belle Elion (January 23, 1918 – February 21, 1999) was an American biochemist and pharmacologist, who shared the 1988 Nobel Prize in Physiology or Medicine with George H. Hitchings and Sir James Black.
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GlaxoSmithKline
GlaxoSmithKline plc (GSK) is a British pharmaceutical company headquartered in Brentford, London.
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Glossitis
Glossitis can mean soreness of the tongue, or more usually inflammation with depapillation of the dorsal surface of the tongue (loss of the lingual papillae), leaving a smooth and erythematous (reddened) surface, (sometimes specifically termed atrophic glossitis).
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Health system
A health system, also sometimes referred to as health care system or as healthcare system, is the organization of people, institutions, and resources that deliver health care services to meet the health needs of target populations.
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Hexosaminidase
Hexosaminidase (beta-acetylaminodeoxyhexosidase, N-acetyl-beta-D-hexosaminidase, N-acetyl-beta-hexosaminidase, N-acetyl hexosaminidase, beta-hexosaminidase, beta-acetylhexosaminidinase, beta-D-N-acetylhexosaminidase, beta-N-acetyl-D-hexosaminidase, beta-N-acetylglucosaminidase, hexosaminidase A, N-acetylhexosaminidase, beta-D-hexosaminidase) is an enzyme involved in the hydrolysis of terminal N-acetyl-D-hexosamine residues in N-acetyl-β-D-hexosaminides.
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HIV/AIDS
Human immunodeficiency virus infection and acquired immune deficiency syndrome (HIV/AIDS) is a spectrum of conditions caused by infection with the human immunodeficiency virus (HIV).
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Hydrogen bond
A hydrogen bond is a partially electrostatic attraction between a hydrogen (H) which is bound to a more electronegative atom such as nitrogen (N), oxygen (O), or fluorine (F), and another adjacent atom bearing a lone pair of electrons.
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Imprimis Pharmaceuticals
Imprimis Pharmaceuticals is a publicly traded pharmaceutical company based in San Diego.
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Isosporiasis
Isosporiasis, also known as cystoisosporiasis, is a human intestinal disease caused by the parasite Isospora belli (now known as Cystoisospora belli).
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Kidney
The kidneys are two bean-shaped organs present in left and right sides of the body in vertebrates.
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Leukopenia
Leukopenia is a decrease in the number of white blood cells (leukocytes) found in the blood, which places individuals at increased risk of infection.
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Liver
The liver, an organ only found in vertebrates, detoxifies various metabolites, synthesizes proteins, and produces biochemicals necessary for digestion.
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Malaria
Malaria is a mosquito-borne infectious disease affecting humans and other animals caused by parasitic protozoans (a group of single-celled microorganisms) belonging to the Plasmodium type.
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Martin Shkreli
Martin Shkreli (born 1983) is an American businessman, former hedge fund manager, and convicted felon.
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Medicines for Malaria Venture
Medicines for Malaria Venture (MMV), a not-for-profit public-private partnership, was established as a foundation in Switzerland in 1999.
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Methotrexate
Methotrexate (MTX), formerly known as amethopterin, is a chemotherapy agent and immune system suppressant.
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Nobel Prize
The Nobel Prize (Swedish definite form, singular: Nobelpriset; Nobelprisen) is a set of six annual international awards bestowed in several categories by Swedish and Norwegian institutions in recognition of academic, cultural, or scientific advances.
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Online pharmacy
An online pharmacy, Internet pharmacy, or mail-order pharmacy is a pharmacy that operates over the Internet and sends the orders to customers through the mail or shipping companies.
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Plasmodium falciparum
Plasmodium falciparum is a unicellular protozoan parasite of humans, and the deadliest species of Plasmodium that cause malaria in humans.
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Plasmodium vivax
Plasmodium vivax is a protozoal parasite and a human pathogen.
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Pneumocystis jirovecii
Pneumocystis jirovecii (previously P. carinii) is a yeast-like fungus of the genus Pneumocystis.
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Pneumocystis pneumonia
Pneumocystis pneumonia (PCP) is a form of pneumonia that is caused by the yeast-like fungus Pneumocystis jirovecii.
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RNA
Ribonucleic acid (RNA) is a polymeric molecule essential in various biological roles in coding, decoding, regulation, and expression of genes.
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SOD1
Superoxide dismutase also known as superoxide dismutase 1 or SOD1 is an enzyme that in humans is encoded by the SOD1 gene, located on chromosome 21.
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Steric effects
Steric effects are nonbonding interactions that influence the shape (conformation) and reactivity of ions and molecules.
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Sulfadiazine
Sulfadiazine is an antibiotic.
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Sulfadoxine/pyrimethamine
Sulfadoxine/pyrimethamine, sold under the brandname Fansidar, is a combination medication used to treat malaria.
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Sulfamethoxazole
Sulfamethoxazole (SMZ or SMX) is an antibiotic.
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Sulfonamide (medicine)
Sulfonamide (also called sulphonamide, sulfa drugs or sulpha drugs) is the basis of several groups of drugs.
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Switzerland
Switzerland, officially the Swiss Confederation, is a sovereign state in Europe.
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Sydney Grammar School
Sydney Grammar School (colloquially known as Grammar) is an independent, non-denominational, day school for boys, located in Darlinghurst, Edgecliff and St Ives, all suburbs of Sydney, Australia.
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Tay–Sachs disease
Tay–Sachs disease is a genetic disorder that results in the destruction of nerve cells in the brain and spinal cord.
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Tetrahydrofolic acid
Tetrahydrofolic acid, or tetrahydrofolate, is a folic acid derivative.
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The Guardian
The Guardian is a British daily newspaper.
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The New York Times
The New York Times (sometimes abbreviated as The NYT or The Times) is an American newspaper based in New York City with worldwide influence and readership.
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The Washington Post
The Washington Post is a major American daily newspaper founded on December 6, 1877.
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Thrombocytopenia
Thrombocytopenia is a condition characterized by abnormally low levels of thrombocytes, also known as platelets, in the blood.
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Toxoplasmic chorioretinitis
Toxoplasma chorioretinitis, more simply known as ocular toxoplasmosis, is probably the most common cause of infections in the back of the eye (posterior segment) worldwide.
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Toxoplasmosis
Toxoplasmosis is a parasitic disease caused by Toxoplasma gondii.
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Trimethoprim
Trimethoprim (TMP) is an antibiotic used mainly in the treatment of bladder infections.
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Turing Pharmaceuticals
Turing Pharmaceuticals is a pharmaceutical company incorporated in Zug, Switzerland, with offices in New York City.
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University of Sydney
The University of Sydney (informally, USyd or USYD) is an Australian public research university in Sydney, Australia.
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WHO Model List of Essential Medicines
The WHO Model List of Essential Medicines (EML), published by the World Health Organization (WHO), contains the medications considered to be most effective and safe to meet the most important needs in a health system.
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4-Aminobenzoic acid
4-Aminobenzoic acid (also known as para-aminobenzoic acid or PABA because the number 4 carbon in the benzene ring is also known as the para position) is an organic compound with the formula H2NC6H4CO2H.
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Redirects here:
ATC code P01BD01, C12H13ClN4, Darachlor, Daraclor, Darapram, Daraprim, Daraprime, Disulone, Erbaprelina, Khloridin, Malacid, Malocid, Malocide, Maloprim, Pirimecidan, Tindurin, Tinduring.
References
[1] https://en.wikipedia.org/wiki/Pyrimethamine
