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16 relations: Boxed warning, Dyspareunia, Estrogen, Estrogen receptor, Estrogen receptor alpha, Estrogen receptor beta, Fispemifene, Food and Drug Administration, Menopause, New Drug Application, Oral administration, Progestin, Raloxifene, Selective estrogen receptor modulator, Shionogi, Vaginal epithelium.
Boxed warning
In the United States, a boxed warning (sometimes "black box warning", colloquially) is a type of warning that appears on the package insert for certain prescription drugs, so called because the U.S. Food and Drug Administration specifies that it is formatted with a 'box' or border around the text.
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Dyspareunia
Dyspareunia is painful sexual intercourse due to medical or psychological causes.
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Estrogen
Estrogen, or oestrogen, is the primary female sex hormone.
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Estrogen receptor
Estrogen receptors (ERs) are a group of proteins found inside cells.
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Estrogen receptor alpha
Estrogen receptor alpha (ERα), also known as NR3A1 (nuclear receptor subfamily 3, group A, member 1), is one of two main types of estrogen receptor, a nuclear receptor that is activated by the sex hormone estrogen.
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Estrogen receptor beta
Estrogen receptor beta (ER-β), also known as NR3A2 (nuclear receptor subfamily 3, group A, member 2), is one of two main types of estrogen receptor, a nuclear receptor which is activated by the sex hormone estrogen.
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Fispemifene
Fispemifene (INN, USAN) (developmental code name HM-101) is a nonsteroidal selective estrogen receptor modulator (SERM) of the triphenylethylene group that was developed for the treatment of male hypogonadism but was abandoned and never marketed.
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Food and Drug Administration
The Food and Drug Administration (FDA or USFDA) is a federal agency of the United States Department of Health and Human Services, one of the United States federal executive departments.
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Menopause
Menopause, also known as the climacteric, is the time in most women's lives when menstrual periods stop permanently, and they are no longer able to bear children.
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New Drug Application
The Food and Drug Administration's New Drug Application (NDA) is the vehicle in the United States through which drug sponsors formally propose that the FDA approve a new pharmaceutical for sale and marketing.
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Oral administration
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Progestin
A progestin is a type of medication which is used most commonly in hormonal birth control and menopausal hormone therapy.
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Raloxifene
Raloxifene, developed by Eli Lilly in 1997 and sold under the brand name Evista among others, is a medication which is used in the prevention and treatment of osteoporosis in postmenopausal women and to reduce the risk of breast cancer in postmenopausal women with osteoporosis or at high risk for breast cancer.
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Selective estrogen receptor modulator
Selective estrogen receptor modulators (SERMs) are a class of drugs that act on the estrogen receptor (ER).
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Shionogi
is a Japanese pharmaceutical company best known for developing Crestor.
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Vaginal epithelium
The vaginal epithelium is the aglandular inner lining of the vagina consisting of multiple layers of (squamous) cells.
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ATC code G03XC05, ATCvet code QG03XC05, C24H23ClO2, Osphena.
