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11 relations: Allosteric modulator, Cannabinoid, Cannabinoid receptor type 1, CP 55,940, GAT100, PSNCBAM-1, Receptor (biochemistry), Receptor antagonist, Rimonabant, Second messenger system, ZCZ-011.
Allosteric modulator
In biochemistry and pharmacology, an allosteric modulator (allo- from the Greek meaning "other") is a substance which indirectly influences (modulates) the effects of a primary ligand that directly activates or deactivates the function of a target protein.
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Cannabinoid
A cannabinoid is one of a class of diverse chemical compounds that acts on cannabinoid receptors in cells that alter neurotransmitter release in the brain.
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Cannabinoid receptor type 1
The cannabinoid type 1 receptor, often abbreviated as CB1, is a G protein-coupled cannabinoid receptor located in the central and peripheral nervous system.
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CP 55,940
CP 55,940 is a cannabinoid which mimics the effects of naturally occurring THC (one of the psychoactive compounds found in cannabis).
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GAT100
GAT100 is a negative allosteric modulator of the cannabinoid CB1 receptor.
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PSNCBAM-1
PSNCBAM-1 is a negative allosteric modulator of the cannabinoid CB1 receptor.
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Receptor (biochemistry)
In biochemistry and pharmacology, a receptor is a protein molecule that receives chemical signals from outside a cell.
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Receptor antagonist
A receptor antagonist is a type of receptor ligand or drug that blocks or dampens a biological response by binding to and blocking a receptor rather than activating it like an agonist.
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Rimonabant
Rimonabant (also known as SR141716; trade names Acomplia, Zimulti) is an anorectic antiobesity drug that was first approved in Europe in 2006 but was withdrawn worldwide in 2008 due to serious psychiatric side effects; it was never approved in the United States.
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Second messenger system
Second messengers are intracellular signaling molecules released by the cell in response to exposure to extracellular signaling molecules—the first messengers.
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ZCZ-011
ZCZ-011 is a positive allosteric modulator of the cannabinoid CB1 receptor.
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