50 relations: Alkyl, Alternating hemiplegia, Antihistamine, Antihypertensive drug, Bile, Biological half-life, Blood plasma, Blood proteins, Blood–brain barrier, Calcium channel blocker, Calmodulin, Canadian Pharmacists Association, Cell death, Contraindication, CYP2D6, Depression (mood), Derivative (chemistry), Dihydropyridine, Diltiazem, Diphenylmethylpiperazine, Dopamine receptor D2, Epilepsy, Extrapyramidal symptoms, Glucuronide, Heart arrhythmia, Hydrochloride, Hydroxy group, Hydroxyzine, Hypotension, Intracellular, Janssen Pharmaceutica, Japan, Migraine, Motor neuron, Muscle atrophy, Oral administration, Parkinson's disease, Peripheral artery disease, Pharmacodynamics, Pharmacokinetics, Sedative, Skeletal muscle, Spinal cord, Spinal muscular atrophy, Stroke, United States, Verapamil, Vertigo, Voltage-gated calcium channel, 5-HT receptor.
Alkyl
In organic chemistry, an alkyl substituent is an alkane missing one hydrogen.
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Alternating hemiplegia
Alternating hemiplegia is a form of hemiplegia that has an ipsilateral and contralateral presentation in different parts of the body.
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Antihistamine
Antihistamines are drugs which treat allergic rhinitis and other allergies.
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Antihypertensive drug
Antihypertensives are a class of drugs that are used to treat hypertension (high blood pressure).
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Bile
Bile or gall is a dark green to yellowish brown fluid, produced by the liver of most vertebrates, that aids the digestion of lipids in the small intestine.
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Biological half-life
The biological half-life of a biological substance is the time it takes for half to be removed by biological processes when the rate of removal is roughly exponential.
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Blood plasma
Blood plasma is a yellowish coloured liquid component of blood that normally holds the blood cells in whole blood in suspension; this makes plasma the extracellular matrix of blood cells.
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Blood proteins
Blood proteins, also termed plasma proteins, are proteins present in blood plasma.
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Blood–brain barrier
The blood–brain barrier (BBB) is a highly selective semipermeable membrane barrier that separates the circulating blood from the brain and extracellular fluid in the central nervous system (CNS).
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Calcium channel blocker
Calcium channel blockers (CCB), calcium channel antagonists or calcium antagonists are several medications that disrupt the movement of calcium through calcium channels.
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Calmodulin
Calmodulin (CaM) (an abbreviation for calcium-modulated protein) is a multifunctional intermediate calcium-binding messenger protein expressed in all eukaryotic cells.
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Canadian Pharmacists Association
The Canadian Pharmacists Association, previously known as the Canadian Pharmaceutical Association, was founded in 1907 in Toronto, Ontario.
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Cell death
Cell death is the event of a biological cell ceasing to carry out its functions.
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Contraindication
In medicine, a contraindication is a condition or factor that serves as a reason to withhold a certain medical treatment due to the harm that it would cause the patient.
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CYP2D6
Cytochrome P450 2D6 (CYP2D6) is an enzyme that in humans is encoded by the CYP2D6 gene.
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Depression (mood)
Depression is a state of low mood and aversion to activity that can affect a person's thoughts, behavior, tendencies, feelings, and sense of well-being.
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Derivative (chemistry)
In chemistry, a derivative is a compound that is derived from a similar compound by a chemical reaction.
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Dihydropyridine
Dihydropyridine is a molecule based upon pyridine, and the parent of a class of molecules that have been semi-saturated with two substituents replacing one double bond.
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Diltiazem
Diltiazem (INN) is a nondihydropyridine (non-DHP) calcium channel blocker used in the treatment of hypertension, angina pectoris, and some types of arrhythmia.
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Diphenylmethylpiperazine
1-(Diphenylmethyl)piperazine, also known as benzhydrylpiperazine, is a chemical compound and piperazine derivative.
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Dopamine receptor D2
Dopamine receptor D2, also known as D2R, is a protein that, in humans, is encoded by the DRD2 gene.
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Epilepsy
Epilepsy is a group of neurological disorders characterized by epileptic seizures.
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Extrapyramidal symptoms
Extrapyramidal symptoms (EPS), also known as extrapyramidal side effects (EPSE), are drug-induced movement disorders that include acute and tardive symptoms.
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Glucuronide
A glucuronide, also known as glucuronoside, is any substance produced by linking glucuronic acid to another substance via a glycosidic bond.
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Heart arrhythmia
Heart arrhythmia (also known as arrhythmia, dysrhythmia, or irregular heartbeat) is a group of conditions in which the heartbeat is irregular, too fast, or too slow.
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Hydrochloride
In chemistry, a hydrochloride is an acid salt resulting, or regarded as resulting, from the reaction of hydrochloric acid with an organic base (e.g. an amine).
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Hydroxy group
A hydroxy or hydroxyl group is the entity with the formula OH.
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Hydroxyzine
Hydroxyzine, sold under the brand names Atarax and Vistaril among others, is a first-generation antihistamine.
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Hypotension
Hypotension is low blood pressure, especially in the arteries of the systemic circulation.
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Intracellular
In cell biology, molecular biology and related fields, the word intracellular means "inside the cell".
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Janssen Pharmaceutica
Janssen Pharmaceutica is a pharmaceutical company headquartered in Beerse, Belgium.
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Japan
Japan (日本; Nippon or Nihon; formally 日本国 or Nihon-koku, lit. "State of Japan") is a sovereign island country in East Asia.
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Migraine
A migraine is a primary headache disorder characterized by recurrent headaches that are moderate to severe.
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Motor neuron
A motor neuron (or motoneuron) is a neuron whose cell body is located in the motor cortex, brainstem or the spinal cord, and whose axon (fiber) projects to the spinal cord or outside of the spinal cord to directly or indirectly control effector organs, mainly muscles and glands.
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Muscle atrophy
Muscle atrophy is defined as a decrease in the mass of the muscle; it can be a partial or complete wasting away of muscle, and is most commonly experienced when persons suffer temporary disabling circumstances such as being restricted in movement and/or confined to bed as when hospitalized.
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Oral administration
| name.
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Parkinson's disease
Parkinson's disease (PD) is a long-term degenerative disorder of the central nervous system that mainly affects the motor system.
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Peripheral artery disease
Peripheral artery disease (PAD) is a narrowing of the arteries other than those that supply the heart or the brain.
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Pharmacodynamics
Pharmacodynamics is the study of the biochemical and physiologic effects of drugs (especially pharmaceutical drugs).
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Pharmacokinetics
Pharmacokinetics (from Ancient Greek pharmakon "drug" and kinetikos "moving, putting in motion"; see chemical kinetics), sometimes abbreviated as PK, is a branch of pharmacology dedicated to determining the fate of substances administered to a living organism.
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Sedative
A sedative or tranquilliser is a substance that induces sedation by reducing irritability or excitement.
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Skeletal muscle
Skeletal muscle is one of three major muscle types, the others being cardiac muscle and smooth muscle.
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Spinal cord
The spinal cord is a long, thin, tubular bundle of nervous tissue and support cells that extends from the medulla oblongata in the brainstem to the lumbar region of the vertebral column.
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Spinal muscular atrophy
Spinal muscular atrophy (SMA) is a rare neuromuscular disorder characterised by loss of motor neurons and progressive muscle wasting, often leading to early death.
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Stroke
A stroke is a medical condition in which poor blood flow to the brain results in cell death.
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United States
The United States of America (USA), commonly known as the United States (U.S.) or America, is a federal republic composed of 50 states, a federal district, five major self-governing territories, and various possessions.
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Verapamil
Verapamil, sold under various trade names, is a medication used for the treatment of high blood pressure, angina (chest pain from not enough blood flow to the heart), and supraventricular tachycardia.
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Vertigo
Vertigo is a symptom where a person feels as if they or the objects around them are moving when they are not.
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Voltage-gated calcium channel
Voltage-gated calcium channels (VGCCs), also known as voltage-dependent calcium channels (VDCCs), are a group of voltage-gated ion channels found in the membrane of excitable cells (e.g., muscle, glial cells, neurons, etc.) with a permeability to the calcium ion Ca2+.
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5-HT receptor
5-hydroxytryptamine receptors or 5-HT receptors, or serotonin receptors, are a group of G protein-coupled receptor and ligand-gated ion channels found in the central and peripheral nervous systems.
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Redirects here:
ATC code N07CA03, ATCvet code QN07CA03, Apo-flunarizine capsules, C26H26F2N2, Flufenal, Fluvert, Issium, Novo-Flunarizine, Sibelium, Vertix, Zinasen.
References
[1] https://en.wikipedia.org/wiki/Flunarizine