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BIBP-3226

Index BIBP-3226

BIBP-3226 is a drug used in scientific research which acts as a potent and selective antagonist for both the Neuropeptide Y receptor Y1 and also the neuropeptide FF receptor. [1]

9 relations: Anorectic, Anxiogenic, British Journal of Pharmacology, Corticotropin-releasing hormone, Lead compound, Neuropeptide FF receptor, Neuropeptide Y, Neuropeptide Y receptor Y1, Receptor antagonist.

Anorectic

An anorectic or anorexic is a drug which reduces appetite, resulting in lower food consumption, leading to weight loss.

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Anxiogenic

An anxiogenic or panicogenic substance is one that causes anxiety.

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British Journal of Pharmacology

The British Journal of Pharmacology is a biweekly peer-reviewed medical journal covering all aspects of experimental pharmacology.

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Corticotropin-releasing hormone

Corticotropin-releasing hormone (CRH) (also known as corticotropin-releasing factor (CRF) or corticoliberin; corticotropin may also be spelled corticotrophin) is a peptide hormone involved in the stress response.

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Lead compound

A lead compound (i.e. a "leading" compound, not to be confused with various compounds of the metallic element lead) in drug discovery is a chemical compound that has pharmacological or biological activity likely to be therapeutically useful, but may nevertheless have suboptimal structure that requires modification to fit better to the target; lead drugs offer the prospect of being followed by back-up compounds.

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Neuropeptide FF receptor

The neuropeptide FF receptors are members of the G-protein coupled receptor superfamily of integral membrane proteins which bind the pain modulatory neuropeptides AF and FF.

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Neuropeptide Y

Neuropeptide Y (NPY) is a 36 amino-acid neuropeptide that is involved in various physiological and homeostatic processes in both the central and peripheral nervous systems.

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Neuropeptide Y receptor Y1

Neuropeptide Y receptor type 1 is a protein that in humans is encoded by the NPY1R gene.

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Receptor antagonist

A receptor antagonist is a type of receptor ligand or drug that blocks or dampens a biological response by binding to and blocking a receptor rather than activating it like an agonist.

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References

[1] https://en.wikipedia.org/wiki/BIBP-3226

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