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12 relations: DBL-583, Dopamine reuptake inhibitor, Dopamine transporter, GBR-12783, GBR-13069, GBR-13098, Ioflupane (123I), Isotopic labeling, Parkinson's disease, Piperazine, Tritium, Vanoxerine.
DBL-583
DBL-583 is a selective dopamine reuptake inhibitor of the piperazine chemical class.
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Dopamine reuptake inhibitor
A dopamine reuptake inhibitor (DRI) is a class of drug which acts as a reuptake inhibitor of the monoamine neurotransmitter dopamine by blocking the action of the dopamine transporter (DAT).
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Dopamine transporter
The dopamine transporter (also dopamine active transporter, DAT, SLC6A3) is a membrane-spanning protein that pumps the neurotransmitter dopamine out of the synaptic cleft back into cytosol.
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GBR-12783
GBR-12783 is a psychostimulant which acts as a selective dopamine reuptake inhibitor.
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GBR-13069
GBR-13069 is a psychostimulant and selective dopamine reuptake inhibitor.
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GBR-13098
GBR-13098 is a psychostimulant and selective dopamine uptake inhibitor.
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Ioflupane (123I)
Ioflupane (123I) is the International Nonproprietary Name of a phenyltropane compound which is a neuro-imaging radiopharmaceutical drug, used by nuclear medicine physicians for the diagnosis of Parkinson's disease and the differential diagnosis of Parkinson's disease over other disorders presenting similar symptoms.
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Isotopic labeling
Isotopic labeling (or isotopic labelling) is a technique used to track the passage of an isotope (an atom with a detectable variation) through a reaction, metabolic pathway, or cell.
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Parkinson's disease
Parkinson's disease (PD) is a long-term degenerative disorder of the central nervous system that mainly affects the motor system.
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Piperazine
Piperazine is an organic compound that consists of a six-membered ring containing two nitrogen atoms at opposite positions in the ring.
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Tritium
Tritium (or; symbol or, also known as hydrogen-3) is a radioactive isotope of hydrogen.
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Vanoxerine
Vanoxerine (GBR-12909) is a piperazine derivative which is a potent and selective dopamine reuptake inhibitor (DRI).
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