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27 relations: Alanine aminopeptidase, Analgesic, Antidepressant, Antidiarrhoeal, Anxiolytic, British Journal of Pharmacology, Cholecystokinin, Cholecystokinin antagonist, Disulfide, Ecadotril, Enkephalin, Enkephalinase, Enzyme inhibitor, Hypoventilation, Ibuprofen, Δ-opioid receptor, Μ-opioid receptor, Journal of Pharmacology and Experimental Therapeutics, Leu-enkephalin, Met-enkephalin, Morphine, Neprilysin, Phenylalanine, Prodrug, Racecadotril, RB-120, RB-3007.
Alanine aminopeptidase
Membrane alanyl aminopeptidase also known as alanyl aminopeptidase (AAP) or aminopeptidase N (AP-N) is an enzyme that in humans is encoded by the ANPEP gene.
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Analgesic
An analgesic or painkiller is any member of the group of drugs used to achieve analgesia, relief from pain.
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Antidepressant
Antidepressants are drugs used for the treatment of major depressive disorder and other conditions, including dysthymia, anxiety disorders, obsessive–compulsive disorder, eating disorders, chronic pain, neuropathic pain and, in some cases, dysmenorrhoea, snoring, migraine, attention-deficit hyperactivity disorder (ADHD), addiction, dependence, and sleep disorders.
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Antidiarrhoeal
An anti-diarrhoeal drug (or anti-diarrheal drug in American English) is any medication which provides symptomatic relief for diarrhoea.
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Anxiolytic
An anxiolytic (also antipanic or antianxiety agent) is a medication or other intervention that inhibits anxiety.
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British Journal of Pharmacology
The British Journal of Pharmacology is a biweekly peer-reviewed medical journal covering all aspects of experimental pharmacology.
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Cholecystokinin
Cholecystokinin (CCK or CCK-PZ; from Greek chole, "bile"; cysto, "sac"; kinin, "move"; hence, move the bile-sac (gallbladder)) is a peptide hormone of the gastrointestinal system responsible for stimulating the digestion of fat and protein.
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Cholecystokinin antagonist
A cholecystokinin antagonist is a specific type of receptor antagonist which blocks the receptor sites for the peptide hormone cholecystokinin (CCK).
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Disulfide
In chemistry, a disulfide refers to a functional group with the structure R−S−S−R′.
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Ecadotril
Ecadotril is a neutral endopeptidase inhibitor ((NEP) EC 3.4.24.11) and determined by the presence of peptidase family M13 as a neutral endopeptidase inhibited by phosphoramidon.
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Enkephalin
An enkephalin (occasionally spelled encephalin) is a pentapeptide involved in regulating nociception in the body.
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Enkephalinase
Enkephalinases are enzymes that degrade endogenous enkephalin opioid peptides.
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Enzyme inhibitor
4QI9) An enzyme inhibitor is a molecule that binds to an enzyme and decreases its activity.
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Hypoventilation
Hypoventilation (also known as respiratory depression) occurs when ventilation is inadequate (hypo meaning "below") to perform needed gas exchange.
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Ibuprofen
Ibuprofen is a medication in the nonsteroidal anti-inflammatory drug (NSAID) class that is used for treating pain, fever, and inflammation.
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Δ-opioid receptor
The δ-opioid receptor, also known as delta opioid receptor or simply delta receptor, abbreviated DOR, is an inhibitory 7-transmembrane G-protein coupled receptor coupled to the G protein Gi/G0 and has enkephalins as its endogenous ligands.
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Μ-opioid receptor
The μ-opioid receptors (MOR) are a class of opioid receptors with a high affinity for enkephalins and beta-endorphin, but a low affinity for dynorphins.
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Journal of Pharmacology and Experimental Therapeutics
The Journal of Pharmacology and Experimental Therapeutics (a.k.a. JPET) is a peer-reviewed scientific journal covering pharmacology.
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Leu-enkephalin
Leu-enkephalin is an endogenous opioid peptide neurotransmitter with the amino acid sequence Tyr-Gly-Gly-Phe-Leu that is found naturally in the brains of many animals, including humans.
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Met-enkephalin
Met-enkephalin, also known as metenkefalin (INN), sometimes referred to as opioid growth factor (OGF), is a naturally occurring, endogenous opioid peptide that has opioid effects of a relatively short duration.
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Morphine
Morphine is a pain medication of the opiate variety which is found naturally in a number of plants and animals.
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Neprilysin
Neprilysin, also known as membrane metallo-endopeptidase (MME), neutral endopeptidase (NEP), cluster of differentiation 10 (CD10), and common acute lymphoblastic leukemia antigen (CALLA) is an enzyme that in humans is encoded by the MME gene.
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Phenylalanine
Phenylalanine (symbol Phe or F) is an α-amino acid with the formula.
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Prodrug
A prodrug is a medication or compound that, after administration, is metabolized (i.e., converted within the body) into a pharmacologically active drug.
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Racecadotril
Racecadotril, also known as acetorphan, is an antidiarrheal drug which acts as a peripherally acting enkephalinase inhibitor.
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RB-120
RB-120 ((N-((S)-2-benzyl-3-1-oxopropyl)-l-alanine benzyl ester) is an orally active analog of the drug RB-101. It acts as an enkephalinase inhibitor, which is used in scientific research.
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RB-3007
RB-3007 is an orally active analogue of RB-101.
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References
[1] https://en.wikipedia.org/wiki/RB-101
