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15 relations: Acute myeloid leukemia, Alpha hydroxy acid, Alpha-Ketoglutaric acid, D2HGDH, Glioma, Glutaric acid, Histone methylation, Hydroxyacid-oxoacid transhydrogenase, Isocitrate dehydrogenase, L2HGDH, Oncogene, Tumor suppressor, 2-hydroxyglutarate dehydrogenase, 2-hydroxyglutarate synthase, 2-Hydroxyglutaric aciduria.
Acute myeloid leukemia
Acute myeloid leukemia (AML) is a cancer of the myeloid line of blood cells, characterized by the rapid growth of abnormal cells that build up in the bone marrow and blood and interfere with normal blood cells.
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Alpha hydroxy acid
α-Hydroxy acids, or alpha hydroxy acids (AHAs), are a class of chemical compounds that consist of a carboxylic acid substituted with a hydroxyl group on the adjacent carbon.
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Alpha-Ketoglutaric acid
α-Ketoglutaric acid (2-oxoglutaric acid) is one of two ketone derivatives of glutaric acid.
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D2HGDH
D-2-hydroxyglutarate dehydrogenase, mitochondrial is an enzyme that in humans is encoded by the D2HGDH gene.
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Glioma
A glioma is a type of tumor that starts in the glial cells of the brain or the spine.
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Glutaric acid
Glutaric acid is the organic compound with the formula C3H6(COOH)2.
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Histone methylation
Histone methylation is a process by which methyl groups are transferred to amino acids of histone proteins that make up nucleosomes, which the DNA double helix wraps around to form chromosomes.
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Hydroxyacid-oxoacid transhydrogenase
In enzymology, a hydroxyacid-oxoacid transhydrogenase is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are (S)-3-hydroxybutanoate and 2-oxoglutarate, whereas its two products are acetoacetate and (R)-2-hydroxyglutarate.
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Isocitrate dehydrogenase
Isocitrate dehydrogenase (IDH) and is an enzyme that catalyzes the oxidative decarboxylation of isocitrate, producing alpha-ketoglutarate (α-ketoglutarate) and CO2.
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L2HGDH
L-2-hydroxyglutarate dehydrogenase, mitochondrial is an enzyme that in humans is encoded by the L2HGDH gene, also known as C14orf160, on chromosome 14.
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Oncogene
An oncogene is a gene that has the potential to cause cancer.
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Tumor suppressor
A tumor suppressor gene, or antioncogene, is a gene that protects a cell from one step on the path to cancer.
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2-hydroxyglutarate dehydrogenase
2-hydroxyglutarage dehydrogenase may refer to.
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2-hydroxyglutarate synthase
In enzymology, a 2-hydroxyglutarate synthase is an enzyme that catalyzes the chemical reaction The 3 substrates of this enzyme are propanoyl-CoA, H2O, and glyoxylate, whereas its two products are 2-hydroxyglutarate and CoA.
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2-Hydroxyglutaric aciduria
2-hydroxyglutaric aciduria is a rare neurometabolic disorder characterized by the significantly elevated levels of hydroxyglutaric acid in ones urine.
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Redirects here:
(D)-2-hydroxyglutarate, 2-HG, 2-Hydroxyglutaric acid, 2-hydroxyglutarate, 2HG, Alpha-hydroxyglutarate, C5H8O5, Hydroxyglutaric acid.
References
[1] https://en.wikipedia.org/wiki/Alpha-Hydroxyglutaric_acid
