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28 relations: Alternative complement pathway, C5-convertase, C8 complex, CD59, Cell membrane, Cell wall, Classical complement pathway, Complement component 5, Complement component 6, Complement component 7, Complement component 9, Complement system, Cytolysin, Diffusion, Glycocalyx, Homology (biology), Hydrophile, Hydrophobe, Immune system, Lectin pathway, Lipid bilayer, Lysis, MACPF, Neisseria, Paroxysmal nocturnal hemoglobinuria, Pathogen, Protein, Terminal complement pathway deficiency.
Alternative complement pathway
The alternative pathway of the complement system is an innate component of the immune system's natural defense against infections.
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C5-convertase
C5 convertase is an enzyme belonging to a family of serine proteases that play key role in the innate immunity.
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C8 complex
Complement component 8 is a protein involved in the complement system.
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CD59
CD59 glycoprotein, also known as MAC-inhibitory protein (MAC-IP), membrane inhibitor of reactive lysis (MIRL), or protectin, is a protein that in humans is encoded by the CD59 gene.
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Cell membrane
The cell membrane (also known as the plasma membrane or cytoplasmic membrane, and historically referred to as the plasmalemma) is a biological membrane that separates the interior of all cells from the outside environment (the extracellular space).
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Cell wall
A cell wall is a structural layer surrounding some types of cells, just outside the cell membrane.
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Classical complement pathway
The classical complement pathway is one of three pathways which activate the complement system, which is part of the immune system.
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Complement component 5
Complement component 5 is a protein that in humans is encoded by the C5 gene.
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Complement component 6
Complement component 6 is a protein that in humans is encoded by the C6 gene.
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Complement component 7
Complement component 7 is a protein involved in the complement system of the innate immune system.
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Complement component 9
Complement component 9 (C9) is a protein involved in the complement system, which is part of the innate immune system.
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Complement system
The complement system is a part of the immune system that enhances (complements) the ability of antibodies and phagocytic cells to clear microbes and damaged cells from an organism, promotes inflammation, and attacks the pathogen's cell membrane.
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Cytolysin
Cytolysin refers to the substance secreted by microorganisms, plants or animals that is specifically toxic to individual cells, in many cases causing their dissolution through lysis.
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Diffusion
Diffusion is the net movement of molecules or atoms from a region of high concentration (or high chemical potential) to a region of low concentration (or low chemical potential) as a result of random motion of the molecules or atoms.
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Glycocalyx
The glycocalyx, also known as the pericellular matrix, is a glycoprotein and glycolipid covering that surrounds the cell membranes of some bacteria, epithelia, and other cells.
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Homology (biology)
In biology, homology is the existence of shared ancestry between a pair of structures, or genes, in different taxa.
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Hydrophile
A hydrophile is a molecule or other molecular entity that is attracted to water molecules and tends to be dissolved by water.
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Hydrophobe
In chemistry, hydrophobicity is the physical property of a molecule (known as a hydrophobe) that is seemingly repelled from a mass of water.
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Immune system
The immune system is a host defense system comprising many biological structures and processes within an organism that protects against disease.
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Lectin pathway
The lectin pathway is a type of cascade reaction in the complement system, similar in structure to the classical complement pathway, in that, after activation, it proceeds through the action of C4 and C2 to produce activated complement proteins further down the cascade.
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Lipid bilayer
The lipid bilayer (or phospholipid bilayer) is a thin polar membrane made of two layers of lipid molecules.
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Lysis
Lysis (Greek λύσις lýsis, "a loosing" from λύειν lýein, "to unbind") refers to the breaking down of the membrane of a cell, often by viral, enzymic, or osmotic (that is, "lytic") mechanisms that compromise its integrity.
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MACPF
The Membrane Attack Complex/Perforin (MACPF) superfamily, sometimes referred to as the MACPF/CDC superfamily, is named after a domain that is common to the membrane attack complex (MAC) proteins of the complement system (C6, C7, C8α, C8β and C9) and perforin (PF).
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Neisseria
Neisseria is a large genus of bacteria that colonize the mucosal surfaces of many animals.
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Paroxysmal nocturnal hemoglobinuria
Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, acquired, life-threatening disease of the blood characterized by destruction of red blood cells by the complement system, a part of the body's innate immune system.
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Pathogen
In biology, a pathogen (πάθος pathos "suffering, passion" and -γενής -genēs "producer of") or a '''germ''' in the oldest and broadest sense is anything that can produce disease; the term came into use in the 1880s.
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Protein
Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.
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Terminal complement pathway deficiency
Terminal complement pathway deficiency is a genetic condition affecting the complement membrane attack complex (MAC).
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References
[1] https://en.wikipedia.org/wiki/Complement_membrane_attack_complex
