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AICA ribonucleotide

Index AICA ribonucleotide

5-Aminoimidazole-4-carboxamide ribonucleotide (AICAR) is an intermediate in the generation of inosine monophosphate. [1]

26 relations: Acadesine, Action potential, Adenosine, Adenosine monophosphate, AMP-activated protein kinase, ATP-sensitive potassium channel, De novo synthesis, French Anti-Doping Agency, GLUT4, Inflammation, Inosine monophosphate synthase, Inosinic acid, Ischemia, Ischemic preconditioning, Ligature (medicine), Myocyte, Nitric oxide, Nucleoside, Nucleotide, Reactive oxygen species, Reperfusion therapy, Sarcolemma, Structural analog, Vascular occlusion, World Anti-Doping Agency, 2009 Tour de France.

Acadesine

Acadesine (INN), also known as 5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside, AICA-riboside, and AICAR, is an AMP-activated protein kinase activator which is used for the treatment of acute lymphoblastic leukemia and may have applications in treating other disorders such as diabetes.

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Action potential

In physiology, an action potential occurs when the membrane potential of a specific axon location rapidly rises and falls: this depolarisation then causes adjacent locations to similarly depolarise.

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Adenosine

Adenosine is both a chemical found in many living systems and a medication.

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Adenosine monophosphate

Adenosine monophosphate (AMP), also known as 5'-adenylic acid, is a nucleotide.

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AMP-activated protein kinase

5' AMP-activated protein kinase or AMPK or 5' adenosine monophosphate-activated protein kinase is an enzyme (EC 2.7.11.31) that plays a role in cellular energy homeostasis.

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ATP-sensitive potassium channel

An ATP-sensitive potassium channel (or KATP channel) is a type of potassium channel that is gated by intracellular nucleotides, ATP and ADP.

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De novo synthesis

De novo synthesis refers to the synthesis of complex molecules from simple molecules such as sugars or amino acids, as opposed to recycling after partial degradation.

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French Anti-Doping Agency

The French Anti-Doping Agency (French: Agence française de lutte contre le dopage, AFLD) is an independent public authority formed in 2006 and charged with ensuring that participants in sports in France do not violate rules regarding doping.

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GLUT4

Glucose transporter type 4 (GLUT-4), also known as solute carrier family 2, facilitated glucose transporter member 4, is a protein encoded, in humans, by the SLC2A4 gene.

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Inflammation

Inflammation (from inflammatio) is part of the complex biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or irritants, and is a protective response involving immune cells, blood vessels, and molecular mediators.

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Inosine monophosphate synthase

Bifunctional purine biosynthesis protein PURH is a protein that in humans is encoded by the ATIC gene.

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Inosinic acid

Inosinic acid or inosine monophosphate (IMP) is a nucleoside monophosphate.

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Ischemia

Ischemia or ischaemia is a restriction in blood supply to tissues, causing a shortage of oxygen that is needed for cellular metabolism (to keep tissue alive).

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Ischemic preconditioning

Ischemic preconditioning (IPC) is an experimental technique for producing resistance to the loss of blood supply, and thus oxygen, to tissues of many types.

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Ligature (medicine)

In surgery or medical procedure, a ligature consists of a piece of thread (suture) tied around an anatomical structure, usually a blood vessel or another hollow structure (e.g. urethra) to shut it off.

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Myocyte

A myocyte (also known as a muscle cell) is the type of cell found in muscle tissue.

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Nitric oxide

Nitric oxide (nitrogen oxide or nitrogen monoxide) is a colorless gas with the formula NO.

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Nucleoside

Nucleosides are glycosylamines that can be thought of as nucleotides without a phosphate group.

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Nucleotide

Nucleotides are organic molecules that serve as the monomer units for forming the nucleic acid polymers deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), both of which are essential biomolecules within all life-forms on Earth.

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Reactive oxygen species

Reactive oxygen species (ROS) are chemically reactive chemical species containing oxygen.

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Reperfusion therapy

Reperfusion therapy is a medical treatment to restore blood flow, either through or around, blocked arteries, typically after a heart attack (myocardial infarction (MI)).

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Sarcolemma

The sarcolemma (sarco (from sarx) from Greek; flesh, and lemma from Greek; sheath) also called the myolemma, is the cell membrane of a striated muscle fiber cell.

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Structural analog

A structural analog, also known as a chemical analog or simply an analog, is a compound having a structure similar to that of another compound, but differing from it in respect to a certain component.

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Vascular occlusion

Vascular occlusion is a blockage of a blood vessel, usually with a clot.

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World Anti-Doping Agency

The World Anti-Doping Agency (WADA; Agence mondiale antidopage, AMA) is a foundation initiated by the International Olympic Committee based in Canada to promote, coordinate and monitor the fight against drugs in sports.

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2009 Tour de France

The 2009 Tour de France was the 96th edition of the Tour de France, one of cycling's Grand Tours.

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Redirects here:

5-Aminoimidazole-4-carboxamide ribotide, 5-aminoimidazole-4-carboxamide ribotide, Aminoimidazole carboxamide ribonucleotide, C9H15N4O8P, Z-nucleotide.

References

[1] https://en.wikipedia.org/wiki/AICA_ribonucleotide

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