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Burimamide

Index Burimamide

Burimamide is an antagonist at the H2 and H3 histamine receptors. [1]

10 relations: Cimetidine, GlaxoSmithKline, Histamine, Histamine H2 receptor, Histamine H3 receptor, Metiamide, Peptic ulcer disease, Receptor (biochemistry), Receptor antagonist, Thiourea.

Cimetidine

Cimetidine, sold under the brand name Tagamet among others, is a histamine H2 receptor antagonist that inhibits stomach acid production.

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GlaxoSmithKline

GlaxoSmithKline plc (GSK) is a British pharmaceutical company headquartered in Brentford, London.

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Histamine

Histamine is an organic nitrogenous compound involved in local immune responses, as well as regulating physiological function in the gut and acting as a neurotransmitter for the brain, spinal cord, and uterus.

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Histamine H2 receptor

H2 receptors are positively coupled to adenylate cyclase via Gs.

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Histamine H3 receptor

Histamine H3 receptors are expressed in the central nervous system and to a lesser extent the peripheral nervous system, where they act as autoreceptors in presynaptic histaminergic neurons, and also control histamine turnover by feedback inhibition of histamine synthesis and release.

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Metiamide

Metiamide is a histamine H2 receptor antagonist developed from another H2 antagonist, burimamide.

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Peptic ulcer disease

Peptic ulcer disease (PUD) is a break in the lining of the stomach, first part of the small intestine or occasionally the lower esophagus.

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Receptor (biochemistry)

In biochemistry and pharmacology, a receptor is a protein molecule that receives chemical signals from outside a cell.

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Receptor antagonist

A receptor antagonist is a type of receptor ligand or drug that blocks or dampens a biological response by binding to and blocking a receptor rather than activating it like an agonist.

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Thiourea

Thiourea is an organosulfur compound with the formula SC(NH2)2.

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Redirects here:

C9H16N4S.

References

[1] https://en.wikipedia.org/wiki/Burimamide

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