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Indole-3-carbinol

Index Indole-3-carbinol

Indole-3-carbinol (C9H9NO) is produced by the breakdown of the glucosinolate glucobrassicin, which can be found at relatively high levels in cruciferous vegetables such as broccoli, cabbage, cauliflower, brussels sprouts, collard greens and kale. [1]

50 relations: Aflatoxin, Aflatoxin B1, Animal testing, Anticarcinogen, Antioxidant, Apoptosis, Atherosclerosis, Autoantibody, Autoimmune disease, Biochemical Pharmacology (journal), BRAF (gene), Broccoli, Brussels sprout, Cabbage, Cancer, Carbon, Carcinogen, Cauliflower, Cell culture, Cell cycle, Cell growth, Collard greens, Cruciferous vegetables, Dietary supplement, DNA, Estrogen, G1 phase, Glucobrassicin, Glucosinolate, Human papillomavirus infection, Hydrogen, Kale, Medical research, Melanoma, Metabolism, Metastasis, Methanol, Mouse, NEDD4, Neoplasm, Nitrogen, Oxygen, Protein kinase B, PTEN (gene), Rainbow trout, Randomized controlled trial, Rat, S phase, Systemic lupus erythematosus, V600E.

Aflatoxin

Aflatoxins are poisonous carcinogens that are produced by certain molds (Aspergillus flavus and Aspergillus parasiticus) which grow in soil, decaying vegetation, hay, and grains.

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Aflatoxin B1

Aflatoxin B1 is an aflatoxin produced by Aspergillus flavus and A. parasiticus.

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Animal testing

Animal testing, also known as animal experimentation, animal research and in vivo testing, is the use of non-human animals in experiments that seek to control the variables that affect the behavior or biological system under study.

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Anticarcinogen

An anticarcinogen (also known as a carcinopreventive agent) is a substance that counteracts the effects of a carcinogen or inhibits the development of cancer.

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Antioxidant

Antioxidants are molecules that inhibit the oxidation of other molecules.

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Apoptosis

Apoptosis (from Ancient Greek ἀπόπτωσις "falling off") is a process of programmed cell death that occurs in multicellular organisms.

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Atherosclerosis

Atherosclerosis is a disease in which the inside of an artery narrows due to the build up of plaque.

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Autoantibody

An autoantibody is an antibody (a type of protein) produced by the immune system that is directed against one or more of the individual's own proteins.

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Autoimmune disease

An autoimmune disease is a condition arising from an abnormal immune response to a normal body part.

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Biochemical Pharmacology (journal)

Biochemical Pharmacology is a peer-reviewed medical journal published by Elsevier.

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BRAF (gene)

BRAF is a human gene that encodes a protein called B-Raf.

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Broccoli

Broccoli is an edible green plant in the cabbage family whose large flowering head is eaten as a vegetable.

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Brussels sprout

The Brussels sprout is a member of the Gemmifera Group of cabbages (Brassica oleracea), grown for its edible buds.

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Cabbage

Cabbage or headed cabbage (comprising several cultivars of Brassica oleracea) is a leafy green, red (purple), or white (pale green) biennial plant grown as an annual vegetable crop for its dense-leaved heads.

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Cancer

Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.

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Carbon

Carbon (from carbo "coal") is a chemical element with symbol C and atomic number 6.

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Carcinogen

A carcinogen is any substance, radionuclide, or radiation that promotes carcinogenesis, the formation of cancer.

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Cauliflower

Cauliflower is one of several vegetables in the species Brassica oleracea in the genus Brassica, which is in the family Brassicaceae.

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Cell culture

Cell culture is the process by which cells are grown under controlled conditions, generally outside their natural environment.

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Cell cycle

The cell cycle or cell-division cycle is the series of events that take place in a cell leading to its division and duplication of its DNA (DNA replication) to produce two daughter cells.

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Cell growth

The term cell growth is used in the contexts of biological cell development and cell division (reproduction).

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Collard greens

Collard greens (collards) describes certain loose-leafed cultivars of Brassica oleracea, the same species as many common vegetables, including cabbage (Capitata Group) and broccoli (Botrytis Group).

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Cruciferous vegetables

Cruciferous vegetables are vegetables of the family Brassicaceae (also called Cruciferae) with many genera, species, and cultivars being raised for food production such as cauliflower, cabbage, garden cress, bok choy, broccoli, Brussels sprouts and similar green leaf vegetables.

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Dietary supplement

A dietary supplement is a manufactured product intended to supplement the diet when taken by mouth as a pill, capsule, tablet, or liquid.

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DNA

Deoxyribonucleic acid (DNA) is a thread-like chain of nucleotides carrying the genetic instructions used in the growth, development, functioning and reproduction of all known living organisms and many viruses.

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Estrogen

Estrogen, or oestrogen, is the primary female sex hormone.

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G1 phase

The g1 phase, or Gap 1 phase, is the first of four phases of the cell cycle that takes place in eukaryotic cell division.

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Glucobrassicin

Glucobrassicin is a type of glucosinolate that can be found in almost all cruciferous plants, such as cabbages, broccoli, mustards, and woad.

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Glucosinolate

The glucosinolates are natural components of many pungent plants such as mustard, cabbage, and horseradish.

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Human papillomavirus infection

Human papillomavirus infection is an infection by human papillomavirus (HPV).

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Hydrogen

Hydrogen is a chemical element with symbol H and atomic number 1.

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Kale

Kale or leaf cabbage are certain cultivars of cabbage (Brassica oleracea) grown for their edible leaves.

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Medical research

Biomedical research (or experimental medicine) encompasses a wide array of research, extending from "basic research" (also called bench science or bench research), – involving fundamental scientific principles that may apply to a ''preclinical'' understanding – to clinical research, which involves studies of people who may be subjects in clinical trials.

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Melanoma

Melanoma, also known as malignant melanoma, is a type of cancer that develops from the pigment-containing cells known as melanocytes.

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Metabolism

Metabolism (from μεταβολή metabolē, "change") is the set of life-sustaining chemical transformations within the cells of organisms.

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Metastasis

Metastasis is a pathogenic agent's spread from an initial or primary site to a different or secondary site within the host's body; it is typically spoken of as such spread by a cancerous tumor.

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Methanol

Methanol, also known as methyl alcohol among others, is a chemical with the formula CH3OH (a methyl group linked to a hydroxyl group, often abbreviated MeOH).

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Mouse

A mouse (Mus), plural mice, is a small rodent characteristically having a pointed snout, small rounded ears, a body-length scaly tail and a high breeding rate.

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NEDD4

E3 ubiquitin-protein ligase NEDD4 also known as neural precursor cell expressed developmentally down-regulated protein 4 (NEDD4) is an enzyme that in humans is encoded by the NEDD4 gene.

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Neoplasm

Neoplasia is a type of abnormal and excessive growth of tissue.

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Nitrogen

Nitrogen is a chemical element with symbol N and atomic number 7.

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Oxygen

Oxygen is a chemical element with symbol O and atomic number 8.

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Protein kinase B

Protein kinase B (PKB), also known as Akt, is a serine/threonine-specific protein kinase that plays a key role in multiple cellular processes such as glucose metabolism, apoptosis, cell proliferation, transcription and cell migration.

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PTEN (gene)

Phosphatase and tensin homolog (PTEN) is a protein that, in humans, is encoded by the PTEN gene.

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Rainbow trout

The rainbow trout (Oncorhynchus mykiss) is a trout and species of salmonid native to cold-water tributaries of the Pacific Ocean in Asia and North America.

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Randomized controlled trial

A randomized controlled trial (or randomized control trial; RCT) is a type of scientific (often medical) experiment which aims to reduce bias when testing a new treatment.

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Rat

Rats are various medium-sized, long-tailed rodents in the superfamily Muroidea.

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S phase

S phase (synthesis phase) is the part of the cell cycle in which DNA is replicated, occurring between G1 phase and G2 phase.

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Systemic lupus erythematosus

Systemic lupus erythematosus (SLE), also known simply as lupus, is an autoimmune disease in which the body's immune system mistakenly attacks healthy tissue in many parts of the body.

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V600E

V600E is a mutation of the BRAF gene in which valine (V) is substituted by glutamic acid (E) at aminoacid 600.

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Redirects here:

1H-indole-3-methanol, 3-hydroxymethylindole, 3-indolemethanol, 3-indolylcarbinol, C9H9NO, I3C, Indole-3-methanol.

References

[1] https://en.wikipedia.org/wiki/Indole-3-carbinol

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