22 relations: Cluster of differentiation, Cytokine, Dendritic cell, Gene, Glycosylphosphatidylinositol, Granulocyte-macrophage colony-stimulating factor, Innate immune system, Interleukin 4, Ligand, Lipopolysaccharide, Lipopolysaccharide binding protein, Liver, Lymphocyte antigen 96, Macrophage, Monocyte, Neutrophil, Pattern recognition receptor, Protein, Protein–protein interaction, TLR4, Toll-like receptor, Unified atomic mass unit.
The cluster of differentiation (also known as cluster of designation or classification determinant and often abbreviated as CD) is a protocol used for the identification and investigation of cell surface molecules providing targets for immunophenotyping of cells.
Cytokines are a broad and loose category of small proteins (~5–20 kDa) that are important in cell signaling.
Dendritic cells (DCs) are antigen-presenting cells (also known as accessory cells) of the mammalian immune system.
In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.
Glycosylphosphatidylinositol, or glycophosphatidylinositol, or GPI in short, is a glycolipid that can be attached to the C-terminus of a protein during posttranslational modification.
Granulocyte-macrophage colony-stimulating factor (GM-CSF), also known as colony-stimulating factor 2 (CSF2), is a monomeric glycoprotein secreted by macrophages, T cells, mast cells, natural killer cells, endothelial cells and fibroblasts that functions as a cytokine.
The innate immune system, also known as the non-specific immune system or in-born immunity system, is an important subsystem of the overall immune system that comprises the cells and mechanisms involved in the defense of the host from infection by other organisms.
The interleukin 4 (IL4, IL-4) is a cytokine that induces differentiation of naive helper T cells (Th0 cells) to Th2 cells.
In coordination chemistry, a ligand is an ion or molecule (functional group) that binds to a central metal atom to form a coordination complex.
Lipopolysaccharides (LPS), also known as lipoglycans and endotoxins, are large molecules consisting of a lipid and a polysaccharide composed of O-antigen, outer core and inner core joined by a covalent bond; they are found in the outer membrane of Gram-negative bacteria.
Lipopolysaccharide binding protein is a protein that in humans is encoded by the LBP gene.
The liver, an organ only found in vertebrates, detoxifies various metabolites, synthesizes proteins, and produces biochemicals necessary for digestion.
Lymphocyte antigen 96, also known as "MD2," is a protein that in humans is encoded by the LY96 gene.
Macrophages (big eaters, from Greek μακρός (makrós).
Monocytes are a type of leukocyte, or white blood cell.
Neutrophils (also known as neutrocytes) are the most abundant type of granulocytes and the most abundant (40% to 70%) type of white blood cells in most mammals.
Pattern recognition receptors (PRRs) play a crucial role in the proper function of the innate immune system.
Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.
Protein–protein interactions (PPIs) are the physical contacts of high specificity established between two or more protein molecules as a result of biochemical events steered by electrostatic forces including the hydrophobic effect.
Toll-like receptor 4 is a protein that in humans is encoded by the TLR4 gene.
Toll-like receptors (TLRs) are a class of proteins that play a key role in the innate immune system.
The unified atomic mass unit or dalton (symbol: u, or Da) is a standard unit of mass that quantifies mass on an atomic or molecular scale (atomic mass).