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24 relations: ANAPC7, Anaphase, Anaphase-promoting complex, BUB1B, CDC16, CDC27, Cyclin, Cyclin A1, Cyclin-dependent kinase, FBXO5, Gene, HDAC1, Heterotrimeric G protein, Histone deacetylase 2, Leland H. Hartwell, Mad2, MAD2L1, Mitosis, Proceedings of the National Academy of Sciences of the United States of America, Protein–protein interaction, Securin, Separase, Spindle checkpoint, WD40 repeat.
ANAPC7
Anaphase-promoting complex subunit 7 is an enzyme that in humans is encoded by the ANAPC7 gene.
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Anaphase
Anaphase (from the Greek ἀνά, "up" and φάσις, "stage"), is the stage of mitosis after the metaphase when replicated chromosomes are split and the daughter chromatids are moved to opposite poles of the cell.
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Anaphase-promoting complex
Anaphase-promoting complex (also called the cyclosome or APC/C) is an E3 ubiquitin ligase that marks target cell cycle proteins for degradation by the 26S proteasome.
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BUB1B
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta is an enzyme that in humans is encoded by the BUB1B gene.
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CDC16
Cell division cycle protein 16 homolog is a protein that in humans is encoded by the CDC16 gene.
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CDC27
Cell division cycle protein 27 homolog is a protein that in humans is encoded by the CDC27 gene.
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Cyclin
Cyclin is a family of proteins that control the progression of cells through the cell cycle by activating cyclin-dependent kinase (Cdk) enzymes.
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Cyclin A1
Cyclin-A1 is a protein that in humans is encoded by the CCNA1 gene.
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Cyclin-dependent kinase
Gap phase 2. The duration of mitosis in relation to the other phases has been exaggerated in this diagram Cyclin-dependent kinases (CDKs) are a family of sugar kinases first discovered for their role in regulating the cell cycle.
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FBXO5
F-box only protein 5 is a protein that in humans is encoded by the FBXO5 gene.
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Gene
In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.
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HDAC1
Histone deacetylase 1 (HDAC1) is an enzyme that in humans is encoded by the HDAC1 gene.
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Heterotrimeric G protein
"G protein" usually refers to the membrane-associated heterotrimeric G proteins, sometimes referred to as the "large" G proteins (as opposed to the subclass of smaller, monomeric small GTPases).
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Histone deacetylase 2
Histone deacetylase 2 (HDAC2) is an enzyme that in humans is encoded by the HDAC2 gene.
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Leland H. Hartwell
Leland Harrison (Lee) Hartwell (born October 30, 1939, in Los Angeles, California) is former president and director of the Fred Hutchinson Cancer Research Center in Seattle, Washington.
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Mad2
Mad2 (mitotic arrest deficient 2) is an essential spindle checkpoint protein.
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MAD2L1
Mitotic spindle assembly checkpoint protein MAD2A is a protein that in humans is encoded by the MAD2L1 gene.
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Mitosis
In cell biology, mitosis is a part of the cell cycle when replicated chromosomes are separated into two new nuclei.
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Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America (PNAS) is the official scientific journal of the National Academy of Sciences, published since 1915.
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Protein–protein interaction
Protein–protein interactions (PPIs) are the physical contacts of high specificity established between two or more protein molecules as a result of biochemical events steered by electrostatic forces including the hydrophobic effect.
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Securin
Securin is a protein involved in control of the metaphase-anaphase transition and anaphase onset.
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Separase
Separase, also known as separin, is a cysteine protease responsible for triggering anaphase by hydrolysing cohesin, which is the protein responsible for binding sister chromatids during the early stage of anaphase.
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Spindle checkpoint
During the process of cell division, the spindle checkpoint prevents separation of the duplicated chromosomes until each chromosome is properly attached to the spindle apparatus.
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WD40 repeat
The WD40 repeat (also known as the WD or beta-transducin repeat) is a short structural motif of approximately 40 amino acids, often terminating in a tryptophan-aspartic acid (W-D) dipeptide.
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References
[1] https://en.wikipedia.org/wiki/CDC20
