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Torcetrapib

Index Torcetrapib

Torcetrapib (CP-529,414, Pfizer) was a drug being developed to treat hypercholesterolemia (elevated cholesterol levels) and prevent cardiovascular disease. [1]

30 relations: Ammonium formate, Anacetrapib, Arteriosclerosis, Thrombosis, and Vascular Biology, Atorvastatin, Benzotriazole, Cardiovascular disease, CETP inhibitor, Cholesterol, Cholesterylester transfer protein, Dalcetrapib, Ethyl carbamate, Ethyl chloroformate, High-density lipoprotein, Hypercholesterolemia, Jeff Kindler, Journal of Lipid Research, Journal of the American College of Cardiology, Low-density lipoprotein, Medication, Merck & Co., Palladium, Pfizer, Phases of clinical research, Propionaldehyde, Sodium triacetoxyborohydride, Statin, The New England Journal of Medicine, The New York Times, Very low-density lipoprotein, Yahoo! News.

Ammonium formate

Ammonium formate, NH4HCO2, is the ammonium salt of formic acid.

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Anacetrapib

Anacetrapib is a CETP inhibitor which was being developed to treat elevated cholesterol levels in an effort prevent cardiovascular disease.

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Arteriosclerosis, Thrombosis, and Vascular Biology

Arteriosclerosis, Thrombosis, and Vascular Biology (ATVB) is a peer-reviewed medical journal published on behalf of the American Heart Association by Lippincott, an imprint of Wolters Kluwer.

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Atorvastatin

Atorvastatin, marketed under the trade name Lipitor among others, is a member of the medication class known as statins, which are used primarily as a lipid-lowering agent and for prevention of events associated with cardiovascular disease.

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Benzotriazole

Benzotriazole (BTA) is a heterocyclic compound containing three nitrogen atoms, with the chemical formula C6H5N3.

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Cardiovascular disease

Cardiovascular disease (CVD) is a class of diseases that involve the heart or blood vessels.

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CETP inhibitor

A CETP inhibitor is a member of a class of drugs that inhibit cholesterylester transfer protein (CETP).

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Cholesterol

Cholesterol (from the Ancient Greek chole- (bile) and stereos (solid), followed by the chemical suffix -ol for an alcohol) is an organic molecule.

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Cholesterylester transfer protein

Cholesteryl ester transfer protein (CETP), also called plasma lipid transfer protein, is a plasma protein that facilitates the transport of cholesteryl esters and triglycerides between the lipoproteins.

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Dalcetrapib

Dalcetrapib (INN, codenamed JTT-705) is a CETP inhibitor which was being developed by Hoffmann–La Roche until May 2012.

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Ethyl carbamate

Ethyl carbamate (also called urethane) is an organic compound with the formula CH3CH2OC(O)NH2.

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Ethyl chloroformate

Ethyl chloroformate is the ethyl ester of chloroformic acid.

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High-density lipoprotein

High-density lipoproteins (HDL) are one of the five major groups of lipoproteins.

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Hypercholesterolemia

Hypercholesterolemia, also called high cholesterol, is the presence of high levels of cholesterol in the blood.

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Jeff Kindler

Jeffrey B. Kindler (born May 13, 1955) is an American healthcare executive and private investor.

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Journal of Lipid Research

The Journal of Lipid Research is a monthly peer-reviewed scientific journal that was established in 1959.

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Journal of the American College of Cardiology

The Journal of the American College of Cardiology is a peer-reviewed medical journal covering all aspects of cardiovascular disease, including original clinical studies, translational investigations with clear clinical relevance, state-of-the-art papers, review articles, and editorials interpreting and commenting on the research presented.

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Low-density lipoprotein

Low-density lipoprotein (LDL) is one of the five major groups of lipoprotein which transport all fat molecules around the body in the extracellular water.

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Medication

A medication (also referred to as medicine, pharmaceutical drug, or simply drug) is a drug used to diagnose, cure, treat, or prevent disease.

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Merck & Co.

Merck & Company, Inc., d.b.a. Merck Sharp & Dohme (MSD) outside the United States and Canada, is an American pharmaceutical company and one of the largest pharmaceutical companies in the world.

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Palladium

Palladium is a chemical element with symbol Pd and atomic number 46.

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Pfizer

Pfizer Inc. is an American pharmaceutical conglomerate headquartered in New York City, with its research headquarters in Groton, Connecticut.

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Phases of clinical research

The phases of clinical research are the steps in which scientists do experiments with a health intervention in an attempt to find enough evidence for a process which would be useful as a medical treatment.

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Propionaldehyde

Propionaldehyde or propanal is the organic compound with the formula CH3CH2CHO.

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Sodium triacetoxyborohydride

Sodium triacetoxyborohydride, also known as sodium triacetoxyhydroborate, commonly abbreviated STAB, is a chemical compound with the formula Na(CH3COO)3BH.

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Statin

Statins, also known as HMG-CoA reductase inhibitors, are a class of lipid-lowering medications.

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The New England Journal of Medicine

The New England Journal of Medicine (NEJM) is a weekly medical journal published by the Massachusetts Medical Society.

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The New York Times

The New York Times (sometimes abbreviated as The NYT or The Times) is an American newspaper based in New York City with worldwide influence and readership.

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Very low-density lipoprotein

Very-low-density lipoprotein (VLDL), density relative to extracellular water, is a type of lipoprotein made by the liver.

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Yahoo! News

Yahoo! News is a news website that originated as an internet-based news aggregator by Yahoo!.

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Redirects here:

CETP Inhibitors, CP-529414.

References

[1] https://en.wikipedia.org/wiki/Torcetrapib

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