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CXCR5

Index CXCR5

C-X-C chemokine receptor type 5 (CXC-R5) also known as CD185 (cluster of differentiation 185) or Burkitt lymphoma receptor 1 (BLR1) is a G protein-coupled seven transmembrane receptor for chemokine CXCL13 (also known as BLC) and belongs to the CXC chemokine receptor family. [1]

13 relations: B cell, Burkitt's lymphoma, Cluster of differentiation, CXC chemokine receptors, CXCL13, G protein–coupled receptor, Gene, Lymph node, MEF2C, Multiple sclerosis, P53, Single-nucleotide polymorphism, Spleen.

B cell

B cells, also known as B lymphocytes, are a type of white blood cell of the lymphocyte subtype.

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Burkitt's lymphoma

Burkitt lymphoma is a cancer of the lymphatic system, particularly B lymphocytes found in the germinal center.

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Cluster of differentiation

The cluster of differentiation (also known as cluster of designation or classification determinant and often abbreviated as CD) is a protocol used for the identification and investigation of cell surface molecules providing targets for immunophenotyping of cells.

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CXC chemokine receptors

CXC chemokine receptors are integral membrane proteins that specifically bind and respond to cytokines of the CXC chemokine family.

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CXCL13

chemokine (C-X-C motif) ligand 13 (CXCL13), also known as B lymphocyte chemoattractant (BLC) or B cell-attracting chemokine 1 (BCA-1), is a protein ligand that in humans is encoded by the CXCL13 gene.

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G protein–coupled receptor

G protein–coupled receptors (GPCRs), also known as seven-(pass)-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptor, and G protein–linked receptors (GPLR), constitute a large protein family of receptors that detect molecules outside the cell and activate internal signal transduction pathways and, ultimately, cellular responses.

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Gene

In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.

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Lymph node

A lymph node or lymph gland is an ovoid or kidney-shaped organ of the lymphatic system, and of the adaptive immune system, that is widely present throughout the body.

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MEF2C

Myocyte-specific enhancer factor 2C also known as MADS box transcription enhancer factor 2, polypeptide C is a protein that in humans is encoded by the MEF2C gene.

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Multiple sclerosis

Multiple sclerosis (MS) is a demyelinating disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged.

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P53

Tumor protein p53, also known as p53, cellular tumor antigen p53 (UniProt name), phosphoprotein p53, tumor suppressor p53, antigen NY-CO-13, or transformation-related protein 53 (TRP53), is any isoform of a protein encoded by homologous genes in various organisms, such as TP53 (humans) and Trp53 (mice).

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Single-nucleotide polymorphism

A single-nucleotide polymorphism, often abbreviated to SNP (plural), is a variation in a single nucleotide that occurs at a specific position in the genome, where each variation is present to some appreciable degree within a population (e.g. > 1%).

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Spleen

The spleen is an organ found in virtually all vertebrates.

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Redirects here:

BLR1, Burkitt lymphoma receptor 1, CD185, CXCR5 (gene).

References

[1] https://en.wikipedia.org/wiki/CXCR5

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