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Membrane transport protein

Index Membrane transport protein

A membrane transport protein (or simply transporter) is a membrane protein involved in the movement of ions, small molecules, or macromolecules, such as another protein, across a biological membrane. [1]

61 relations: Active transport, Adenine nucleotide translocator, Antiporter, Aquaporin, ATP synthase, ATP-binding cassette transporter, Atypical SLCs, Biological membrane, Colicin, Cotransporter, Cystic fibrosis transmembrane conductance regulator, Diphtheria toxin, Dopamine transporter, Electrochemical gradient, Electron transport chain, Enzyme, F-ATPase, Facilitated diffusion, Glucose transporter, GLUT1, Glutamate aspartate transporter, Glutamate transporter, Gramicidin, Holin, Integral membrane protein, Ion, Ion channel, Ionomycin, Ligand-gated ion channel, Macromolecule, Membrane protein, Molecule, Monoamine transporter, Na+/K+-ATPase, Nigericin, Norepinephrine transporter, P-glycoprotein, P-type ATPase, Permease, Phosphate, Phosphorylation, Plasma membrane Ca2+ ATPase, Protein, Protein kinase, Proton pump, Reverse transport, Rhodopsin, Riboflavin carrier protein, Serotonin transporter, SLC1A2, ..., Solute carrier family, Substrate (chemistry), Symporter, Translocase, Transmembrane protein, Transporter Classification Database, V-ATPase, Vesicular monoamine transporter, Vesicular transport protein, Voltage-gated ion channel, Walker motifs. Expand index (11 more) »

Active transport

Active transport is the movement of molecules across a membrane from a region of their lower concentration to a region of their higher concentration—in the direction against the concentration gradient.

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Adenine nucleotide translocator

Adenine nucleotide translocator (ANT), also known as the ADP/ATP translocator, exhanges free ATP with free ADP across the inner mitochondrial membrane.

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Antiporter

An antiporter (also called exchanger or counter-transporter) is a cotransporter and integral membrane protein involved in secondary active transport of two or more different molecules or ions across a phospholipid membrane such as the plasma membrane in opposite directions.

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Aquaporin

Aquaporins, also called water channels, are integral membrane proteins from a larger family of major intrinsic proteins that form pores in the membrane of biological cells, mainly facilitating transport of water between cells.

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ATP synthase

ATP synthase is an enzyme that creates the energy storage molecule adenosine triphosphate (ATP).

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ATP-binding cassette transporter

ATP-binding cassette transporters (ABC transporters) are members of a transport system superfamily that is one of the largest and is possibly one of the oldest families with representatives in all extant phyla from prokaryotes to humans.

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Atypical SLCs

Atypical SLCs are novel plausible secondary active or facilitative transansporter proteins that share ancestral background with the known solute carriers.

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Biological membrane

A biological membrane or biomembrane is an enclosing or separating membrane that acts as a selectively permeable barrier within living things.

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Colicin

A colicin is a type of bacteriocin produced by and toxic to some strains of Escherichia coli.

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Cotransporter

Cotransporters are a subcategory of membrane transport proteins (transporters) that couple the favorable movement of one molecule with its concentration gradient and unfavorable movement of another molecule against its concentration gradient.

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Cystic fibrosis transmembrane conductance regulator

Cystic fibrosis transmembrane conductance regulator (CFTR) is a membrane protein and chloride channel in vertebrates that is encoded by the CFTR gene.

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Diphtheria toxin

Diphtheria toxin is an exotoxin secreted by Corynebacterium diphtheriae, the pathogenic bacterium that causes diphtheria.

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Dopamine transporter

The dopamine transporter (also dopamine active transporter, DAT, SLC6A3) is a membrane-spanning protein that pumps the neurotransmitter dopamine out of the synaptic cleft back into cytosol.

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Electrochemical gradient

An electrochemical gradient is a gradient of electrochemical potential, usually for an ion that can move across a membrane.

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Electron transport chain

An electron transport chain (ETC) is a series of complexes that transfer electrons from electron donors to electron acceptors via redox (both reduction and oxidation occurring simultaneously) reactions, and couples this electron transfer with the transfer of protons (H+ ions) across a membrane.

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Enzyme

Enzymes are macromolecular biological catalysts.

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F-ATPase

F-ATPase, also known as F-Type ATPase (also called ATP synthase), is an ATPase found in bacterial plasma membranes, in mitochondrial inner membranes (in oxidative phosphorylation, where it is known as Complex V), and in chloroplast thylakoid membranes.

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Facilitated diffusion

Facilitated diffusion (also known as facilitated transport or passive-mediated transport) is the process of spontaneous passive transport (as opposed to active transport) of molecules or ions across a biological membrane via specific transmembrane integral proteins.

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Glucose transporter

Glucose transporters are a wide group of membrane proteins that facilitate the transport of glucose across the plasma membrane.

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GLUT1

Glucose transporter 1 (or GLUT1), also known as solute carrier family 2, facilitated glucose transporter member 1 (SLC2A1), is a uniporter protein that in humans is encoded by the SLC2A1 gene.

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Glutamate aspartate transporter

Solute carrier family 1 (glial high-affinity glutamate transporter), member 3, also known as SLC1A3, is a protein that, in humans, is encoded by the SLC1A3 gene.

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Glutamate transporter

Glutamate transporters are a family of neurotransmitter transporter proteins that move glutamate – the principal excitatory neurotransmitter – across a membrane.

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Gramicidin

Gramicidin is a heterogeneous mixture of three antibiotic compounds, gramicidins A, B and C, making up 80%, 6%, and 14%, respectively, all of which are obtained from the soil bacterial species Bacillus brevis and called collectively gramicidin D. Gramicidin D contains linear pentadecapeptides, that is chains made up of 15 amino acids.

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Holin

Holins are a diverse group of small proteins produced by dsDNA bacteriophages in order to trigger and control the degradation of the host's cell wall at the end of the lytic cycle.

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Integral membrane protein

An integral membrane protein (IMP) is a type of membrane protein that is permanently attached to the biological membrane.

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Ion

An ion is an atom or molecule that has a non-zero net electrical charge (its total number of electrons is not equal to its total number of protons).

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Ion channel

Ion channels are pore-forming membrane proteins that allow ions to pass through the channel pore.

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Ionomycin

Ionomycin is an ionophore produced by the bacterium Streptomyces conglobatus.

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Ligand-gated ion channel

Ligand-gated ion channels (LICs, LGIC), also commonly referred as ionotropic receptors, are a group of transmembrane ion-channel proteins which open to allow ions such as Na+, K+, Ca2+, and/or Cl− to pass through the membrane in response to the binding of a chemical messenger (i.e. a ligand), such as a neurotransmitter.

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Macromolecule

A macromolecule is a very large molecule, such as protein, commonly created by the polymerization of smaller subunits (monomers).

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Membrane protein

Membrane proteins are proteins that interact with, or are part of, biological membranes.

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Molecule

A molecule is an electrically neutral group of two or more atoms held together by chemical bonds.

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Monoamine transporter

Monoamine transporters (MATs) are protein structures that function as integral plasma-membrane transporters to regulate concentrations of extracellular monoamine neurotransmitters.

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Na+/K+-ATPase

-ATPase (sodium-potassium adenosine triphosphatase, also known as the pump or sodium–potassium pump) is an enzyme (an electrogenic transmembrane ATPase) found in the plasma membrane of all animal cells.

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Nigericin

Nigericin is an antibiotic derived from Streptomyces hygroscopicus.

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Norepinephrine transporter

The norepinephrine transporter (NET), also known as solute carrier family 6 member 2 (SLC6A2), is a protein that in humans is encoded by the SLC6A2 gene.

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P-glycoprotein

P-glycoprotein 1 (permeability glycoprotein, abbreviated as P-gp or Pgp) also known as multidrug resistance protein 1 (MDR1) or ATP-binding cassette sub-family B member 1 (ABCB1) or cluster of differentiation 243 (CD243) is an important protein of the cell membrane that pumps many foreign substances out of cells.

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P-type ATPase

The P-type ATPases, also known as E1-E2 ATPases, are a large group of evolutionarily related ion and lipid pumps that are found in bacteria, archaea, and eukaryotes.

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Permease

The permeases are membrane transport proteins, a class of multipass transmembrane proteins that allow the diffusion of a specific molecule in or out of the cell in the direction of a concentration gradient, a form of facilitated diffusion.

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Phosphate

A phosphate is chemical derivative of phosphoric acid.

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Phosphorylation

In chemistry, phosphorylation of a molecule is the attachment of a phosphoryl group.

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Plasma membrane Ca2+ ATPase

The plasma membrane Ca2+ ATPase (PMCA) is a transport protein in the plasma membrane of cells and functions to remove calcium (Ca2+) from the cell.

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Protein

Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.

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Protein kinase

A protein kinase is a kinase enzyme that modifies other proteins by chemically adding phosphate groups to them (phosphorylation).

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Proton pump

A proton pump is an integral membrane protein that builds up a proton gradient across a biological membrane.

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Reverse transport

Reverse transport, or transporter reversal, is a phenomenon in which the substrates of a membrane transport protein are moved in the opposite direction to that of their typical movement by the transporter.

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Rhodopsin

Rhodopsin (also known as visual purple) is a light-sensitive receptor protein involved in visual phototransduction.

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Riboflavin carrier protein

Riboflavin carrier proteins (RFCPs) together with human serum albumin transport flavin mononucleotide (FMN) in the blood circuit.

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Serotonin transporter

The serotonin transporter (SERT or 5-HTT) also known as the sodium-dependent serotonin transporter and solute carrier family 6 member 4 is a protein that in humans is encoded by the SLC6A4 gene.

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SLC1A2

Excitatory amino acid transporter 2 (EAAT2) also known as solute carrier family 1 member 2 (SLC1A2) and glutamate transporter 1 (GLT-1) is a protein that in humans is encoded by the SLC1A2 gene.

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Solute carrier family

The solute carrier (SLC) group of membrane transport proteins include over 400 members organized into 65 families.

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Substrate (chemistry)

In chemistry, a substrate is typically the chemical species being observed in a chemical reaction, which reacts with a reagent to generate a product.

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Symporter

A symporter is an integral membrane protein that is involved in the transport of many differing types of molecules across the cell membrane.

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Translocase

Translocase is a general term for a protein that assists in moving another molecule, usually across a membrane.

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Transmembrane protein

A transmembrane protein (TP) is a type of integral membrane protein that spans the entirety of the biological membrane to which it is permanently attached.

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Transporter Classification Database

The Transporter Classification Database (or TCDB) is an International Union of Biochemistry and Molecular Biology (IUBMB)-approved classification system for membrane transport proteins, including ion channels.

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V-ATPase

Vacuolar-type -ATPase (V-ATPase) is a highly conserved evolutionarily ancient enzyme with remarkably diverse functions in eukaryotic organisms.

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Vesicular monoamine transporter

The vesicular monoamine transporter (VMAT) is a transport protein integrated into the membrane of synaptic vesicles of presynaptic neurons.

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Vesicular transport protein

A vesicular transport protein, or vesicular transporter, is a membrane protein that regulates or facilitates the movement of specific molecules across a vesicle's membrane.

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Voltage-gated ion channel

Voltage-gated ion channels are a class of transmembrane proteins that form ion channels that are activated by changes in the electrical membrane potential near the channel.

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Walker motifs

The Walker A and Walker B motifs are protein sequence motifs, known to have highly conserved three-dimensional structures.

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Redirects here:

Carriage proteins, Carrier (protein), Carrier mediated transport, Carrier protein, Carrier proteins, Carrier-mediate transport, Carrier-mediated transport, Carrier-protein, Cell transporter, Cellular transport, Membrane transport proteins, Membrane transporter, Membrane transporter protein.

References

[1] https://en.wikipedia.org/wiki/Membrane_transport_protein

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