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Cholesterol signaling

Index Cholesterol signaling

Cholesterol is a cell signaling molecule that is highly regulated in eukaryotic cell membranes. [1]

Table of Contents

  1. 31 relations: Activation, Amino acid, Astrocyte, Cardiovascular disease, Cell membrane, Cell signaling, Cholesterol, Enzyme, Eukaryote, Inflammation, Ion channel, LDL receptor, Ligand (biochemistry), Lipid, Lipid raft, Membrane vesicle trafficking, Metabolic syndrome, Molecule, Nerve, Neurodegenerative disease, Palmitoylation, Phosphatidylinositol 4,5-bisphosphate, Phospholipase D, Polyunsaturated fat, Protein, Saturated fat, Signal transduction, Statin, Steroid hormone, Sterol, Substrate presentation.

  2. Cholestanes

Activation

In chemistry and biology, activation is the process whereby something is prepared or excited for a subsequent reaction.

See Cholesterol signaling and Activation

Amino acid

Amino acids are organic compounds that contain both amino and carboxylic acid functional groups.

See Cholesterol signaling and Amino acid

Astrocyte

Astrocytes (from Ancient Greek,, "star" and,, "cavity", "cell"), also known collectively as astroglia, are characteristic star-shaped glial cells in the brain and spinal cord.

See Cholesterol signaling and Astrocyte

Cardiovascular disease

Cardiovascular disease (CVD) is any disease involving the heart or blood vessels.

See Cholesterol signaling and Cardiovascular disease

Cell membrane

The cell membrane (also known as the plasma membrane or cytoplasmic membrane, and historically referred to as the plasmalemma) is a biological membrane that separates and protects the interior of a cell from the outside environment (the extracellular space).

See Cholesterol signaling and Cell membrane

Cell signaling

In biology, cell signaling (cell signalling in British English) is the process by which a cell interacts with itself, other cells, and the environment.

See Cholesterol signaling and Cell signaling

Cholesterol

Cholesterol is the principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils. Cholesterol signaling and Cholesterol are Cholestanes.

See Cholesterol signaling and Cholesterol

Enzyme

Enzymes are proteins that act as biological catalysts by accelerating chemical reactions.

See Cholesterol signaling and Enzyme

Eukaryote

The eukaryotes constitute the domain of Eukarya or Eukaryota, organisms whose cells have a membrane-bound nucleus.

See Cholesterol signaling and Eukaryote

Inflammation

Inflammation (from inflammatio) is part of the biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or irritants.

See Cholesterol signaling and Inflammation

Ion channel

Ion channels are pore-forming membrane proteins that allow ions to pass through the channel pore.

See Cholesterol signaling and Ion channel

LDL receptor

The low-density lipoprotein receptor (LDL-R) is a mosaic protein of 839 amino acids (after removal of 21-amino acid signal peptide) that mediates the endocytosis of cholesterol-rich low-density lipoprotein (LDL).

See Cholesterol signaling and LDL receptor

Ligand (biochemistry)

In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose.

See Cholesterol signaling and Ligand (biochemistry)

Lipid

Lipids are a broad group of organic compounds which include fats, waxes, sterols, fat-soluble vitamins (such as vitamins A, D, E and K), monoglycerides, diglycerides, phospholipids, and others.

See Cholesterol signaling and Lipid

Lipid raft

The plasma membranes of cells contain combinations of glycosphingolipids, cholesterol and protein receptors organised in glycolipoprotein lipid microdomains termed lipid rafts.

See Cholesterol signaling and Lipid raft

Membrane vesicle trafficking

Membrane vesicle trafficking in eukaryotic animal cells involves movement of biochemical signal molecules from synthesis-and-packaging locations in the Golgi body to specific release locations on the inside of the plasma membrane of the secretory cell.

See Cholesterol signaling and Membrane vesicle trafficking

Metabolic syndrome

Metabolic syndrome is a clustering of at least three of the following five medical conditions: abdominal obesity, high blood pressure, high blood sugar, high serum triglycerides, and low serum high-density lipoprotein (HDL).

See Cholesterol signaling and Metabolic syndrome

Molecule

A molecule is a group of two or more atoms held together by attractive forces known as chemical bonds; depending on context, the term may or may not include ions which satisfy this criterion.

See Cholesterol signaling and Molecule

Nerve

A nerve is an enclosed, cable-like bundle of nerve fibers (called axons) in the peripheral nervous system.

See Cholesterol signaling and Nerve

Neurodegenerative disease

A neurodegenerative disease is caused by the progressive loss of neurons, in the process known as neurodegeneration.

See Cholesterol signaling and Neurodegenerative disease

Palmitoylation

Palmitoylation is the covalent attachment of fatty acids, such as palmitic acid, to cysteine (S-palmitoylation) and less frequently to serine and threonine (O-palmitoylation) residues of proteins, which are typically membrane proteins.

See Cholesterol signaling and Palmitoylation

Phosphatidylinositol 4,5-bisphosphate

Phosphatidylinositol 4,5-bisphosphate or PtdIns(4,5)P2, also known simply as PIP2 or PI(4,5)P2, is a minor phospholipid component of cell membranes.

See Cholesterol signaling and Phosphatidylinositol 4,5-bisphosphate

Phospholipase D

Phospholipase D (EC 3.1.4.4, lipophosphodiesterase II, lecithinase D, choline phosphatase, PLD; systematic name phosphatidylcholine phosphatidohydrolase) is an enzyme of the phospholipase superfamily that catalyses the following reaction Phospholipases occur widely, and can be found in a wide range of organisms, including bacteria, yeast, plants, animals, and viruses.

See Cholesterol signaling and Phospholipase D

Polyunsaturated fat

In biochemistry and nutrition, a polyunsaturated fat is a fat that contains a polyunsaturated fatty acid (abbreviated PUFA), which is a subclass of fatty acid characterized by a backbone with two or more carbon–carbon double bonds.

See Cholesterol signaling and Polyunsaturated fat

Protein

Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues.

See Cholesterol signaling and Protein

Saturated fat

A saturated fat is a type of fat in which the fatty acid chains have all single bonds between the carbon atoms.

See Cholesterol signaling and Saturated fat

Signal transduction

Signal transduction is the process by which a chemical or physical signal is transmitted through a cell as a series of molecular events. Cholesterol signaling and signal transduction are biochemistry.

See Cholesterol signaling and Signal transduction

Statin

Statins (or HMG-CoA reductase inhibitors) are a class of medications that reduce illness and mortality in people who are at high risk of cardiovascular disease.

See Cholesterol signaling and Statin

Steroid hormone

A steroid hormone is a steroid that acts as a hormone.

See Cholesterol signaling and Steroid hormone

Sterol

Sterol is an organic compound with formula, whose molecule is derived from that of gonane by replacement of a hydrogen atom on C3 position by a hydroxyl group.

See Cholesterol signaling and Sterol

Substrate presentation

Substrate presentation is a biological process that activates a protein.

See Cholesterol signaling and Substrate presentation

See also

Cholestanes

References

[1] https://en.wikipedia.org/wiki/Cholesterol_signaling