We are working to restore the Unionpedia app on the Google Play Store
OutgoingIncoming
🌟We've simplified our design for better navigation!
Instagram Facebook X LinkedIn

Cluster of differentiation

Index Cluster of differentiation

The cluster of differentiation (also known as cluster of designation or classification determinant and often abbreviated as CD) is a protocol used for the identification and investigation of cell surface molecules providing targets for immunophenotyping of cells. [1]

Table of Contents

  1. 83 relations: Acute myeloid leukemia, Adelaide, Alanine aminopeptidase, Antibody, Antigen, B cell, Barcelona, Blood (journal), Boston, CD135, CD14, CD16, CD19, CD2, CD20, CD22, CD24, CD3 (immunology), CD30, CD31, CD33, CD34, CD38, CD4, CD4+/CD8+ ratio, CD8, Cell adhesion, Cell adhesion molecule, Cell membrane, Cell signaling, Cell sorting, Chemokine, CXCR6, Cytotoxic T cell, Dendritic cell, Endothelium, Epitope, Expressivity (genetics), Flow cytometry, FOXP3, Gene expression, Glycoprotein, Granulocyte, Granulocyte colony-stimulating factor receptor, Growth factor, Harrogate, HIV, HIV/AIDS, IL2RA, Immune system, ... Expand index (33 more) »

  2. Antigens

Acute myeloid leukemia

Acute myeloid leukemia (AML) is a cancer of the myeloid line of blood cells, characterized by the rapid growth of abnormal cells that build up in the bone marrow and blood and interfere with normal blood cell production.

See Cluster of differentiation and Acute myeloid leukemia

Adelaide

Adelaide (Tarntanya) is the capital and most populous city of South Australia, and the fifth-most populous city in Australia. "Adelaide" may refer to either Greater Adelaide (including the Adelaide Hills) or the Adelaide city centre. The demonym Adelaidean is used to denote the city and the residents of Adelaide.

See Cluster of differentiation and Adelaide

Alanine aminopeptidase

Membrane alanyl aminopeptidase also known as alanyl aminopeptidase (AAP) or aminopeptidase N (AP-N) is an enzyme that in humans is encoded by the ANPEP gene.

See Cluster of differentiation and Alanine aminopeptidase

Antibody

An antibody (Ab) is the secreted form of a B cell receptor; the term immunoglobulin (Ig) can refer to either the membrane-bound form or the secreted form of the B cell receptor, but they are, broadly speaking, the same protein, and so the terms are often treated as synonymous.

See Cluster of differentiation and Antibody

Antigen

In immunology, an antigen (Ag) is a molecule, moiety, foreign particulate matter, or an allergen, such as pollen, that can bind to a specific antibody or T-cell receptor. Cluster of differentiation and antigen are antigens.

See Cluster of differentiation and Antigen

B cell

B cells, also known as B lymphocytes, are a type of white blood cell of the lymphocyte subtype.

See Cluster of differentiation and B cell

Barcelona

Barcelona is a city on the northeastern coast of Spain.

See Cluster of differentiation and Barcelona

Blood (journal)

Blood is a peer-reviewed medical journal published by the American Society of Hematology.

See Cluster of differentiation and Blood (journal)

Boston

Boston, officially the City of Boston, is the capital and most populous city in the Commonwealth of Massachusetts in the United States.

See Cluster of differentiation and Boston

CD135

Cluster of differentiation antigen 135 (CD135) also known as fms like tyrosine kinase 3 (FLT-3 with fms standing for "feline McDonough sarcoma"), receptor-type tyrosine-protein kinase FLT3, or fetal liver kinase-2 (Flk2) is a protein that in humans is encoded by the FLT3 gene.

See Cluster of differentiation and CD135

CD14

CD14 (cluster of differentiation 14) is a human protein made mostly by macrophages as part of the innate immune system. Cluster of differentiation and CD14 are clusters of differentiation.

See Cluster of differentiation and CD14

CD16

CD16, also known as FcγRIII, is a cluster of differentiation molecule found on the surface of natural killer cells, neutrophils, monocytes, macrophages, and certain T cells. Cluster of differentiation and CD16 are clusters of differentiation.

See Cluster of differentiation and CD16

CD19

B-lymphocyte antigen CD19, also known as CD19 molecule ('''C'''luster of '''D'''ifferentiation 19), B-Lymphocyte Surface Antigen B4, T-Cell Surface Antigen Leu-12 and CVID3 is a transmembrane protein that in humans is encoded by the gene CD19. Cluster of differentiation and CD19 are clusters of differentiation.

See Cluster of differentiation and CD19

CD2

CD2 (cluster of differentiation 2) is a cell adhesion molecule found on the surface of T cells and natural killer (NK) cells. Cluster of differentiation and CD2 are clusters of differentiation.

See Cluster of differentiation and CD2

CD20

B-lymphocyte antigen CD20 or CD20 is B lymphocyte cell-surface molecule. Cluster of differentiation and CD20 are clusters of differentiation.

See Cluster of differentiation and CD20

CD22

CD22, or cluster of differentiation-22, is a molecule belonging to the SIGLEC family of lectins.

See Cluster of differentiation and CD22

CD24

Signal transducer CD24 also known as cluster of differentiation 24 or heat stable antigen CD24 (HSA) is a protein that in humans is encoded by the CD24 gene.

See Cluster of differentiation and CD24

CD3 (immunology)

CD3 (cluster of differentiation 3) is a protein complex and T cell co-receptor that is involved in activating both the cytotoxic T cell (CD8+ naive T cells) and T helper cells (CD4+ naive T cells). Cluster of differentiation and CD3 (immunology) are clusters of differentiation.

See Cluster of differentiation and CD3 (immunology)

CD30

CD30, also known as TNFRSF8 (TNF receptor superfamily member 8), is a cell membrane protein of the tumor necrosis factor receptor family and a tumor marker.

See Cluster of differentiation and CD30

CD31

Platelet endothelial cell adhesion molecule (PECAM-1) also known as cluster of differentiation 31 (CD31) is a protein that in humans is encoded by the PECAM1 gene found on chromosome17q23.3. Cluster of differentiation and CD31 are clusters of differentiation.

See Cluster of differentiation and CD31

CD33

CD33 or Siglec-3 (sialic acid binding Ig-like lectin 3, SIGLEC3, SIGLEC-3, gp67, p67) is a transmembrane receptor expressed on cells of myeloid lineage.

See Cluster of differentiation and CD33

CD34

CD34 is a transmembrane phosphoglycoprotein protein encoded by the CD34 gene in humans, mice, rats and other species. Cluster of differentiation and CD34 are clusters of differentiation.

See Cluster of differentiation and CD34

CD38

CD38 (cluster of differentiation 38), also known as cyclic ADP ribose hydrolase is a glycoprotein found on the surface of many immune cells (white blood cells), including CD4+, CD8+, B lymphocytes and natural killer cells. Cluster of differentiation and CD38 are clusters of differentiation.

See Cluster of differentiation and CD38

CD4

In molecular biology, CD4 (cluster of differentiation 4) is a glycoprotein that serves as a co-receptor for the T-cell receptor (TCR). Cluster of differentiation and CD4 are clusters of differentiation.

See Cluster of differentiation and CD4

CD4+/CD8+ ratio

The CD4+/CD8+ ratio is the ratio of T helper cells (with the surface marker CD4) to cytotoxic T cells (with the surface marker CD8). Cluster of differentiation and CD4+/CD8+ ratio are clusters of differentiation.

See Cluster of differentiation and CD4+/CD8+ ratio

CD8

CD8 (cluster of differentiation 8) is a transmembrane glycoprotein that serves as a co-receptor for the T-cell receptor (TCR). Cluster of differentiation and CD8 are clusters of differentiation.

See Cluster of differentiation and CD8

Cell adhesion

Cell adhesion is the process by which cells interact and attach to neighbouring cells through specialised molecules of the cell surface.

See Cluster of differentiation and Cell adhesion

Cell adhesion molecule

Cell adhesion molecules (CAMs) are a subset of cell surface proteins that are involved in the binding of cells with other cells or with the extracellular matrix (ECM), in a process called cell adhesion.

See Cluster of differentiation and Cell adhesion molecule

Cell membrane

The cell membrane (also known as the plasma membrane or cytoplasmic membrane, and historically referred to as the plasmalemma) is a biological membrane that separates and protects the interior of a cell from the outside environment (the extracellular space).

See Cluster of differentiation and Cell membrane

Cell signaling

In biology, cell signaling (cell signalling in British English) is the process by which a cell interacts with itself, other cells, and the environment.

See Cluster of differentiation and Cell signaling

Cell sorting

Cell sorting is the process through which a particular cell type is separated from others contained in a sample on the basis of its physical or biological properties, such as size, morphological parameters, viability and both extracellular and intracellular protein expression.

See Cluster of differentiation and Cell sorting

Chemokine

Chemokines, or chemotactic cytokines, are a family of small cytokines or signaling proteins secreted by cells that induce directional movement of leukocytes, as well as other cell types, including endothelial and epithelial cells.

See Cluster of differentiation and Chemokine

CXCR6

C-X-C chemokine receptor type 6 is a protein that in humans is encoded by the CXCR6 gene. Cluster of differentiation and CXCR6 are clusters of differentiation.

See Cluster of differentiation and CXCR6

Cytotoxic T cell

A cytotoxic T cell (also known as TC, cytotoxic T lymphocyte, CTL, T-killer cell, cytolytic T cell, CD8+ T-cell or killer T cell) is a T lymphocyte (a type of white blood cell) that kills cancer cells, cells that are infected by intracellular pathogens (such as viruses or bacteria), or cells that are damaged in other ways.

See Cluster of differentiation and Cytotoxic T cell

Dendritic cell

A dendritic cell (DC) is an antigen-presenting cell (also known as an accessory cell) of the mammalian immune system.

See Cluster of differentiation and Dendritic cell

Endothelium

The endothelium (endothelia) is a single layer of squamous endothelial cells that line the interior surface of blood vessels and lymphatic vessels.

See Cluster of differentiation and Endothelium

Epitope

An epitope, also known as antigenic determinant, is the part of an antigen that is recognized by the immune system, specifically by antibodies, B cells, or T cells.

See Cluster of differentiation and Epitope

Expressivity (genetics)

In genetics, expressivity is the degree to which a phenotype is expressed by individuals having a particular genotype.

See Cluster of differentiation and Expressivity (genetics)

Flow cytometry

Flow cytometry (FC) is a technique used to detect and measure the physical and chemical characteristics of a population of cells or particles.

See Cluster of differentiation and Flow cytometry

FOXP3

FOXP3 (forkhead box P3), also known as scurfin, is a protein involved in immune system responses.

See Cluster of differentiation and FOXP3

Gene expression

Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product that enables it to produce end products, proteins or non-coding RNA, and ultimately affect a phenotype.

See Cluster of differentiation and Gene expression

Glycoprotein

Glycoproteins are proteins which contain oligosaccharide (sugar) chains covalently attached to amino acid side-chains.

See Cluster of differentiation and Glycoprotein

Granulocyte

Granulocytes are cells in the innate immune system characterized by the presence of specific granules in their cytoplasm.

See Cluster of differentiation and Granulocyte

Granulocyte colony-stimulating factor receptor

The granulocyte colony-stimulating factor receptor (G-CSF-R) also known as CD114 (Cluster of Differentiation 114) is a protein that in humans is encoded by the CSF3R gene. Cluster of differentiation and granulocyte colony-stimulating factor receptor are clusters of differentiation.

See Cluster of differentiation and Granulocyte colony-stimulating factor receptor

Growth factor

A growth factor is a naturally occurring substance capable of stimulating cell proliferation, wound healing, and occasionally cellular differentiation.

See Cluster of differentiation and Growth factor

Harrogate

Harrogate is a spa town in the district and county of North Yorkshire, England.

See Cluster of differentiation and Harrogate

HIV

The human immunodeficiency viruses (HIV) are two species of Lentivirus (a subgroup of retrovirus) that infect humans.

See Cluster of differentiation and HIV

HIV/AIDS

The human immunodeficiency virus (HIV) is a retrovirus that attacks the immune system.

See Cluster of differentiation and HIV/AIDS

IL2RA

The Interleukin-2 receptor alpha chain (also called TAC antigen, P55, and mainly CD25) is a protein involved in the assembly of the high-affinity Interleukin-2 receptor, consisting of alpha (IL2RA), beta (IL2RB) and the common gamma chain (IL2RG). Cluster of differentiation and IL2RA are clusters of differentiation.

See Cluster of differentiation and IL2RA

Immune system

The immune system is a network of biological systems that protects an organism from diseases.

See Cluster of differentiation and Immune system

Immune tolerance

Immune tolerance, also known as immunological tolerance or immunotolerance, refers to the immune system's state of unresponsiveness to substances or tissues that would otherwise trigger an immune response.

See Cluster of differentiation and Immune tolerance

Immunophenotyping

Immunophenotyping is a technique used to study the protein expressed by cells.

See Cluster of differentiation and Immunophenotyping

Integrin alpha L

Integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide), also known as ITGAL, is a protein that in humans is encoded by the ITGAL gene. Cluster of differentiation and Integrin alpha L are clusters of differentiation.

See Cluster of differentiation and Integrin alpha L

Integrin alpha M

Integrin alpha M (ITGAM) is one protein subunit that forms heterodimeric integrin alpha-M beta-2 (αMβ2) molecule, also known as macrophage-1 antigen (Mac-1) or complement receptor 3 (CR3).

See Cluster of differentiation and Integrin alpha M

Integrin beta 3

Integrin beta-3 (β3) or CD61 is a protein that in humans is encoded by the ITGB3 gene.

See Cluster of differentiation and Integrin beta 3

KIT (gene)

Proto-oncogene c-KIT is the gene encoding the receptor tyrosine kinase protein known as tyrosine-protein kinase KIT, CD117 (cluster of differentiation 117) or mast/stem cell growth factor receptor (SCFR).

See Cluster of differentiation and KIT (gene)

Kobe

Kobe (Kōbe), officially, is the capital city of Hyōgo Prefecture, Japan.

See Cluster of differentiation and Kobe

Ligand (biochemistry)

In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose.

See Cluster of differentiation and Ligand (biochemistry)

List of human clusters of differentiation

The following is a list of human clusters of differentiation (or CD) molecules. Cluster of differentiation and list of human clusters of differentiation are clusters of differentiation.

See Cluster of differentiation and List of human clusters of differentiation

Major histocompatibility complex

The major histocompatibility complex (MHC) is a large locus on vertebrate DNA containing a set of closely linked polymorphic genes that code for cell surface proteins essential for the adaptive immune system.

See Cluster of differentiation and Major histocompatibility complex

Monoclonal antibody

A monoclonal antibody (mAb, more rarely called moAb) is an antibody produced from a cell lineage made by cloning a unique white blood cell.

See Cluster of differentiation and Monoclonal antibody

Monocyte

Monocytes are a type of leukocyte or white blood cell.

See Cluster of differentiation and Monocyte

Natural killer cell

Natural killer cells, also known as NK cells or large granular lymphocytes (LGL), are a type of cytotoxic lymphocyte critical to the innate immune system.

See Cluster of differentiation and Natural killer cell

Neural cell adhesion molecule

Neural cell adhesion molecule (NCAM), also called CD56, is a homophilic binding glycoprotein expressed on the surface of neurons, glia and skeletal muscle. Cluster of differentiation and Neural cell adhesion molecule are clusters of differentiation.

See Cluster of differentiation and Neural cell adhesion molecule

Oxford

Oxford is a city and non-metropolitan district in Oxfordshire, England, of which it is the county town.

See Cluster of differentiation and Oxford

Paris

Paris is the capital and largest city of France.

See Cluster of differentiation and Paris

Phagocyte

Phagocytes are cells that protect the body by ingesting harmful foreign particles, bacteria, and dead or dying cells.

See Cluster of differentiation and Phagocyte

Platelet

Platelets or thrombocytes are a blood component whose function (along with the coagulation factors) is to react to bleeding from blood vessel injury by clumping, thereby initiating a blood clot.

See Cluster of differentiation and Platelet

PTPRC

Protein tyrosine phosphatase, receptor type, C also known as PTPRC is an enzyme that, in humans, is encoded by the PTPRC gene. Cluster of differentiation and PTPRC are clusters of differentiation.

See Cluster of differentiation and PTPRC

Receptor (biochemistry)

In biochemistry and pharmacology, receptors are chemical structures, composed of protein, that receive and transduce signals that may be integrated into biological systems.

See Cluster of differentiation and Receptor (biochemistry)

Regulatory T cell

The regulatory T cells (Tregs or Treg cells), formerly known as suppressor T cells, are a subpopulation of T cells that modulate the immune system, maintain tolerance to self-antigens, and prevent autoimmune disease.

See Cluster of differentiation and Regulatory T cell

Sialyl-Lewis X

Sialyl LewisX (sLeX), also known as cluster of differentiation 15s (CD15s) or stage-specific embryonic antigen 1 (SSEA-1), is a tetrasaccharide carbohydrate which is usually attached to O-glycans on the surface of cells. Cluster of differentiation and Sialyl-Lewis X are clusters of differentiation.

See Cluster of differentiation and Sialyl-Lewis X

Signal transduction

Signal transduction is the process by which a chemical or physical signal is transmitted through a cell as a series of molecular events.

See Cluster of differentiation and Signal transduction

Stem cell

In multicellular organisms, stem cells are undifferentiated or partially differentiated cells that can change into various types of cells and proliferate indefinitely to produce more of the same stem cell.

See Cluster of differentiation and Stem cell

T cell

T cells are one of the important types of white blood cells of the immune system and play a central role in the adaptive immune response.

See Cluster of differentiation and T cell

T helper cell

The T helper cells (Th cells), also known as CD4+ cells or CD4-positive cells, are a type of T cell that play an important role in the adaptive immune system.

See Cluster of differentiation and T helper cell

Thymus

The thymus (thymuses or thymi) is a specialized primary lymphoid organ of the immune system.

See Cluster of differentiation and Thymus

Transferrin receptor 1

Transferrin receptor protein 1 (TfR1), also known as Cluster of Differentiation 71 (CD71), is a protein that in humans is encoded by the TFRC gene. Cluster of differentiation and Transferrin receptor 1 are clusters of differentiation.

See Cluster of differentiation and Transferrin receptor 1

Transmembrane protein

A transmembrane protein is a type of integral membrane protein that spans the entirety of the cell membrane.

See Cluster of differentiation and Transmembrane protein

Transplant rejection

Transplant rejection occurs when transplanted tissue is rejected by the recipient's immune system, which destroys the transplanted tissue.

See Cluster of differentiation and Transplant rejection

Vienna

Vienna (Wien; Austro-Bavarian) is the capital, most populous city, and one of nine federal states of Austria.

See Cluster of differentiation and Vienna

White blood cell

White blood cells (scientific name leukocytes), also called immune cells or immunocytes, are cells of the immune system that are involved in protecting the body against both infectious disease and foreign invaders.

See Cluster of differentiation and White blood cell

Wollongong

Wollongong (Dharawal: Woolyungah) is a city located in the Illawarra region of New South Wales, Australia.

See Cluster of differentiation and Wollongong

See also

Antigens

References

[1] https://en.wikipedia.org/wiki/Cluster_of_differentiation

Also known as Antigens, cd, Cell marker, Cell surface marker, Cell surface markers, Classification determinant, Cluster differentiation, Cluster of designation, Clusters of differentiation, Human cell differentiation molecules, Leucocyte molecule.

, Immune tolerance, Immunophenotyping, Integrin alpha L, Integrin alpha M, Integrin beta 3, KIT (gene), Kobe, Ligand (biochemistry), List of human clusters of differentiation, Major histocompatibility complex, Monoclonal antibody, Monocyte, Natural killer cell, Neural cell adhesion molecule, Oxford, Paris, Phagocyte, Platelet, PTPRC, Receptor (biochemistry), Regulatory T cell, Sialyl-Lewis X, Signal transduction, Stem cell, T cell, T helper cell, Thymus, Transferrin receptor 1, Transmembrane protein, Transplant rejection, Vienna, White blood cell, Wollongong.