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Codeine-6-glucuronide

Index Codeine-6-glucuronide

Codeine-6-glucuronide (C6G) is a major active metabolite of codeine and may be responsible for as much as 60% of the analgesic effects of codeine. [1]

Table of Contents

  1. 5 relations: Analgesic, Codeine, Glucuronic acid, Morphine-6-glucuronide, UGT2B7.

  2. Glucuronide esters
  3. Opioid metabolites

Analgesic

An analgesic drug, also called simply an analgesic, antalgic, pain reliever, or painkiller, is any member of the group of drugs used for pain management.

See Codeine-6-glucuronide and Analgesic

Codeine

Codeine is an opiate and prodrug of morphine mainly used to treat pain, coughing, and diarrhea.

See Codeine-6-glucuronide and Codeine

Glucuronic acid

Glucuronic acid (from Greek γλεῦκος "sweet wine, must" and οá½–ρον "urine") is a uronic acid that was first isolated from urine (hence the name "uronic acid").

See Codeine-6-glucuronide and Glucuronic acid

Morphine-6-glucuronide

Morphine-6-glucuronide (M6G) is a major active metabolite of morphine. Codeine-6-glucuronide and morphine-6-glucuronide are Glucuronide esters, mu-opioid receptor agonists, Opioid metabolites and Phenols.

See Codeine-6-glucuronide and Morphine-6-glucuronide

UGT2B7

UGT2B7 (UDP-Glucuronosyltransferase-2B7) is a phase II metabolism isoenzyme found to be active in the liver, kidneys, epithelial cells of the lower gastrointestinal tract and also has been reported in the brain.

See Codeine-6-glucuronide and UGT2B7

See also

Glucuronide esters

Opioid metabolites

References

[1] https://en.wikipedia.org/wiki/Codeine-6-glucuronide

Also known as C24H29NO9, C6G.