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Corticosteroids are a class of chemicals that includes the steroid hormones that are produced in the adrenal cortex of vertebrates as well as the synthetic analogues of these hormones. [1]

136 relations: Addison's disease, Adrenal cortex, Adrenal ferredoxin, Adrenal insufficiency, Adverse drug reaction, Aldosterone, Aldosterone synthase, Allergen of the Year, Allergy, Amcinonide, Anabolic steroid, Anxiety, Arthritis, Asthma, Beclometasone dipropionate, Betamethasone, Betamethasone dipropionate, Bile, Brain tumor, Budesonide, Candidiasis, Carbohydrate, Catabolism, Cataract, Central serous retinopathy, Cholesterol, Ciclesonide, Clobetasol propionate, Clobetasone, Colitis, Congenital adrenal hyperplasia, Corticosteroid, Corticosterone, Cortisol, Cortisone, Crohn's disease, Cushing's syndrome, Cutaneous condition, CYP17A1, Cytochrome P450, Depression (mood), Dermatitis, Desonide, Dexamethasone, Diabetes mellitus, Dioscorea mexicana, Diosgenin, Edward Calvin Kendall, Electrolyte, Enzyme, ..., Eosinophil granulocyte, Fludrocortisone, Flunisolide, Fluocinolone acetonide, Fluocinonide, Fluocortolone, Fluorometholone, Fluprednidene acetate, Fluticasone furoate, Fluticasone propionate, Fluticasone/salmeterol, Giant-cell arteritis, Glucocorticoid, Halcinonide, Halometasone, Hepatitis, Hormonal contraception, Hydrocortisone 17-butyrate, Hyperglycemia, Hypernatremia, Hypertension, Hypokalemia, Immune system, Inflammation, Inflammatory bowel disease, Insulin resistance, Kidney, Leukocyte extravasation, Leukotriene, Lewis Hastings Sarett, List of steroid abbreviations, Marker degradation, Medicine, Merck & Co., Metabolic alkalosis, Metabolism, Methylprednisolone, Mineralocorticoid, Mitochondrion, Mometasone furoate, Moon face, Mucous membrane, Nobel Prize, Ondansetron, Ox, Peptic ulcer, Percy Lavon Julian, Peripheral edema, Pharmaceutical drug, Philip Showalter Hench, Phospholipase A2, Phospholipid, Physiology, Prednicarbate, Prednisolone, Prednisone, Progesterone, Prostaglandin, Protein, Retinopathy, Rhinitis, Rhizopus, Russell Earl Marker, Sarcoidosis, Steroid, Steroid 11-beta-hydroxylase, Steroid hormone, Steroid-induced osteoporosis, Stress (biology), Syntex, Systematic review, Systemic lupus erythematosus, Tadeusz Reichstein, Teratology, Tixocortol pivalate, Tobramycin/dexamethasone, Triamcinolone, Triamcinolone acetonide, Ulcerative colitis, Upjohn, Uveitis, Vertebrate, Vitiligo, Zona fasciculata, Zona glomerulosa, 21-Hydroxylase. Expand index (86 more) »

Addison's disease

Addison’s disease (also Addison disease, chronic adrenal insufficiency, hypocortisolism, and hypoadrenalism) is a rare, chronic endocrine system disorder in which the adrenal glands do not produce sufficient steroid hormones (glucocorticoids and mineralocorticoids).

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Adrenal cortex

Situated along the perimeter of the adrenal gland, the adrenal cortex mediates the stress response through the production of mineralocorticoids and glucocorticoids, such as aldosterone and cortisol, respectively.

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Adrenal ferredoxin

Adrenal ferredoxin also known as adrenodoxin or adrenodoxin, mitochondrial or hepatoredoxin or ferredoxin-1 (FDX1) is a protein that in humans is encoded by the FDX1 gene.

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Adrenal insufficiency

Adrenal insufficiency is a condition in which the adrenal glands do not produce adequate amounts of steroid hormones, primarily cortisol; but may also include impaired production of aldosterone (a mineralocorticoid), which regulates sodium conservation, potassium secretion, and water retention.

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Adverse drug reaction

An adverse drug reaction (ADR) is an injury caused by taking a medication.

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Aldosterone is a steroid hormone (mineralocorticoid family) produced by the outer section (zona glomerulosa) of the adrenal cortex in the adrenal gland.

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Aldosterone synthase

Aldosterone synthase is a steroid hydroxylase cytochrome P450 enzyme involved in the biosynthesis of the mineralocorticoid aldosterone.

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Allergen of the Year

Allergen of the Year is an annual "award" of dubious distinction voted upon by the American Contact Dermatitis Society.

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Allergies, also known as allergic diseases, are a number of conditions caused by hypersensitivity of the immune system to something in the environment that normally causes little problem.

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Amcinonide (trade name Cyclocort) is a topical glucocorticoid used to treat itching, redness and swelling associated with several dermatologic conditions such as atopic dermatitis and allergic contact dermatitis.

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Anabolic steroid

Anabolic steroids, technically known as anabolic-androgenic steroids (AAS), are drugs that are structurally related to the cyclic steroid rings system and have similar effects to testosterone in the body.

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Anxiety is an emotion characterized by an unpleasant state of inner turmoil, often accompanied by nervous behavior, such as pacing back and forth, somatic complaints and rumination.

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Arthritis (from Greek arthro-, joint + -itis, inflammation; plural: arthritides) is a form of joint disorder that involves inflammation of one or more joints.

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Asthma (from the Greek ἅσθμα, ásthma, "panting") is a common chronic inflammatory disease of the airways characterized by variable and recurring symptoms, reversible airflow obstruction and bronchospasm.

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Beclometasone dipropionate

Beclometasone dipropionate (INN modified) or beclomethasone dipropionate (USAN, former BAN) is a potent glucocorticoid steroid.

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Betamethasone is a potent glucocorticoid steroid with anti-inflammatory and immunosuppressive properties.

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Betamethasone dipropionate

Betamethasone dipropionate is a glucocorticoid steroid with anti-inflammatory and immunosuppressive abilities.

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Bile or gall is a dark green to yellowish brown fluid, produced by the liver of most vertebrates, that aids the digestion of lipids in the small intestine.

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Brain tumor

A brain tumor or intracranial neoplasm occurs when abnormal cells form within the brain.

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Budesonide is a glucocorticoid steroid used in inhaled formulations for the treatment of asthma, COPD and non-infectious rhinitis (including hay fever and other allergies), and for treatment and prevention of nasal polyposis.

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Candidiasis is a fungal infection due to any type of Candida (a type of yeast).

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A carbohydrate is a biological molecule consisting of carbon (C), hydrogen (H) and oxygen (O) atoms, usually with a hydrogen:oxygen atom ratio of 2:1 (as in water); in other words, with the empirical formula (where m could be different from n).

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Catabolism (from Greek κάτω kato, "downward" and βάλλειν ballein, "to throw") is the set of metabolic pathways that breaks down molecules into smaller units that are either oxidized to release energy, or used in other anabolic reactions.

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A cataract is a clouding of the lens in the eye leading to a decrease in vision.

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Central serous retinopathy

Central serous retinopathy (CSR), also known as central serous chorioretinopathy (CSC), is an eye disease which causes visual impairment, often temporary, usually in one eye.

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Cholesterol, from the Ancient Greek chole- (bile) and stereos (solid) followed by the chemical suffix -ol for an alcohol, is an organic molecule.

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Ciclesonide is a glucocorticoid used to treat asthma and allergic rhinitis.

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Clobetasol propionate

Clobetasol propionate is a corticosteroid of the glucocorticoid class used to treat various skin disorders including eczema and psoriasis.

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Clobetasone (INN) is a corticosteroid used in dermatology, for treating such skin inflammation as seen in eczema, psoriasis and other forms of dermatitis, and ophthalmology.

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Colitis (pl. colitides) refers to an inflammation of the colon.

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Congenital adrenal hyperplasia

Congenital adrenal hyperplasia (CAH) are any of several autosomal recessive diseases resulting from mutations of genes for enzymes mediating the biochemical steps of production of cortisol from cholesterol by the adrenal glands (steroidogenesis).

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Corticosteroids are a class of chemicals that includes the steroid hormones that are produced in the adrenal cortex of vertebrates as well as the synthetic analogues of these hormones.

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Corticosterone, also known as 17-deoxycortisol and 11β,21-dihydroprogesterone, is a 21-carbon steroid hormone of the corticosteroid type produced in the cortex of the adrenal glands in rodents and other non-human animals.

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Cortisol is a steroid hormone, in the glucocorticoid class of hormones, and is produced in humans by the zona fasciculata of the adrenal cortex within the adrenal gland.

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Cortisone (or; 17-hydroxy-11-dehydrocorticosterone) is a 21-carbon steroid hormone.

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Crohn's disease

Crohn's disease, also known as Crohn syndrome and regional enteritis, is a type of inflammatory bowel disease (IBD) that may affect any part of the gastrointestinal tract from mouth to anus.

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Cushing's syndrome

Cushing's syndrome, also known as hypercortisolism, Itsenko-Cushing syndrome, and hyperadrenocorticism, is a collection of signs and symptoms due to prolonged exposure to cortisol.

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Cutaneous condition

A cutaneous condition is any medical condition that affects the integumentary system — the organ system that encloses the body and includes skin, hair, nails, and related muscle and glands.

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Cytochrome P450 17A1, or steroid 17-alpha-monooxygenase, or 17α-hydroxylase/17,20 lyase/17,20 desmolase is an enzyme that in humans is encoded by the CYP17A1 gene.

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Cytochrome P450

Cytochromes P450 (CYPs) belong to the superfamily of proteins containing a heme cofactor and, therefore, are hemoproteins.

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Depression (mood)

Depression is a state of low mood and aversion to activity that can affect a person's thoughts, behavior, feelings and sense of well-being.

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Dermatitis, also known as eczema, is inflammation of the skin.

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Desonide is the generic name of a low-potency topical corticosteroid that has been available since the 1970s.

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Dexamethasone is a type of steroid medication.

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Diabetes mellitus

Diabetes mellitus (DM), commonly referred to as diabetes, is a group of metabolic diseases in which there are high blood sugar levels over a prolonged period.

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Dioscorea mexicana

Dioscorea mexicana, Mexican yam or cabeza de negro is a species of yam in the genus Dioscorea.

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Diosgenin, a steroid sapogenin, is the product of hydrolysis by acids, strong bases, or enzymes of saponins, extracted from the tubers of Dioscorea wild yam, such as the Kokoro.

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Edward Calvin Kendall

Edward Calvin Kendall (March 8, 1886 – May 4, 1972) was an American chemist.

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An electrolyte (Etymology: Greek lytós able to be untied or loosened) is a substance that produces an electrically conducting solution when dissolved in a polar solvent, such as water.

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Enzymes are macromolecular biological catalysts.

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Eosinophil granulocyte

Eosinophil granulocytes, usually called eosinophils or eosinophiles (or, less commonly, acidophils), are white blood cells and one of the immune system components responsible for combating multicellular parasites and certain infections in vertebrates.

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Fludrocortisone (also called 9α-fluorocortisol or 9α-fluorohydrocortisone) is a synthetic corticosteroid with moderate glucocorticoid potency and much greater mineralocorticoid potency.

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Flunisolide (marketed as AeroBid, Nasalide, Nasarel) is a corticosteroid often prescribed as treatment for allergic rhinitis.

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Fluocinolone acetonide

Fluocinolone acetonide is a corticosteroid primarily used in dermatology to reduce skin inflammation and relieve itching.

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Fluocinonide (Fluonex, Lidex, Lidex-E, Lonide, Lyderm, and Vanos) is a potent glucocorticoid used topically as an anti-inflammatory agent for the treatment of skin disorders such as eczema and seborrhoeic dermatitis.

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Fluocortolone is a glucocorticoid used in the treatment of several conditions, including hemorrhoids.

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Fluorometholone is a corticosteroid, most often used after laser-based refractive surgery.

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Fluprednidene acetate

Fluprednidene acetate is a corticosteroid.

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Fluticasone furoate

Fluticasone furoate is a synthetic corticosteroid derived from fluticasone, marketed by GlaxoSmithKline as Veramyst (US) and Avamys (Australia, Canada, EU, South Africa, Mexico, Israel and South Korea) for the treatment of allergic rhinitis.

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Fluticasone propionate

Fluticasone propionate belongs to a class of drugs known as corticosteroids, specifically glucocorticoids, which are hormones that predominantly affect the metabolism of carbohydrates and, to a lesser extent, fat and protein.

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The combination preparation fluticasone/salmeterol is a formulation containing fluticasone propionate and salmeterol xinafoate, used in the management of asthma and chronic obstructive pulmonary disease (COPD).

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Giant-cell arteritis

Giant-cell arteritis (GCA or temporal arteritis or cranial arteritis) or Horton disease is an inflammatory disease of blood vessels most commonly involving large and medium arteries of the head, predominantly the branches of the external carotid artery.

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Glucocorticoids (GCs) are a class of steroid hormones which bind to the glucocorticoid receptor (GR), that is present in almost every vertebrate animal cell.

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Halcinonide is a high potency corticosteroid, in group II (second most potent group) under US classification.

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Halometasone is a potent (Group III) synthetic tri-halogenated corticosteroid for topical application possessing pronounced anti-inflammatory, antiexudative, antiepidermoplastic, antiallergic, and antipruritic properties.

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Hepatitis (plural: hepatitides) is a medical condition defined by the inflammation of the liver and characterized by the presence of inflammatory cells in the tissue of the organ.

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Hormonal contraception

Hormonal contraception refers to birth control methods that act on the endocrine system.

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Hydrocortisone 17-butyrate

Hydrocortisone 17-butyrate is a form of hydrocortisone butyrate.

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Hyperglycemia, or high blood sugar (also spelled hyperglycaemia or hyperglycæmia, not to be confused with the opposite disorder, hypoglycemia) is a condition in which an excessive amount of glucose circulates in the blood plasma.

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Hypernatremia or hypernatraemia is an elevated sodium level in the blood.

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Hypertension (HTN or HT), also known as high blood pressure or arterial hypertension, is a chronic medical condition in which the blood pressure in the arteries is persistently elevated.

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Hypokalemia (American English) or hypokalaemia (British English), also hypopotassemia or hypopotassaemia (ICD-9), refers to the condition in which the concentration of potassium (K+) in the blood is low.

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Immune system

The immune system is a system of many biological structures and processes within an organism that protects against disease.

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Inflammation (Latin, inflammatio) is part of the complex biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or irritants.

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Inflammatory bowel disease

Inflammatory bowel disease (IBD) is a group of inflammatory conditions of the colon and small intestine.

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Insulin resistance

Insulin resistance (IR) is a physiological condition in which cells fail to respond to the normal actions of the hormone insulin.

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The kidneys are bean-shaped organs that serve several essential regulatory roles in vertebrates.

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Leukocyte extravasation

Defination: Movement of circulating neutrphils into tissue is called extra vasation.

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Leukotrienes are a family of eicosanoid inflammatory mediators produced in leukocytes by the oxidation of arachidonic acid by the enzyme arachidonate 5-lipoxygenase.

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Lewis Hastings Sarett

Lewis Hastings Sarett (December 22, 1917 – November 29, 1999) was an American organic chemist.

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List of steroid abbreviations

The steroid hormones are referred to by various abbreviations in the biological literature.

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Marker degradation

The Marker degradation is a three-step synthetic route in steroid chemistry developed by American chemist Russell Earl Marker in 1938–40.

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Medicine (British English; American English) is the science and practice of the diagnosis, treatment, and prevention of disease.

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Merck & Co.

Merck & Co., Inc., d.b.a. Merck Sharp & Dohme (MSD) outside the United States and Canada, is an American pharmaceutical company and one of the largest pharmaceutical companies in the world.

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Metabolic alkalosis

Metabolic alkalosis is a metabolic condition in which the pH of tissue is elevated beyond the normal range (7.35-7.45).

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Metabolism (from μεταβολή metabolē, "change") is the set of life-sustaining chemical transformations within the cells of living organisms.

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Methylprednisolone is a synthetic glucocorticoid or corticosteroid drug.

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Mineralocorticoid(s) are a class of steroid hormones characterized by their influence on salt and water balances.

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The mitochondrion (plural mitochondria) is a double membrane-bound organelle found in most eukaryotic cells.

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Mometasone furoate

Mometasone furoate is a glucocorticosteroid used topically to reduce inflammation of the skin or in the airways.

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Moon face

Moon facies, or moon face, is a medical sign in which the face develops a rounded appearance due to fat deposits on the sides of the face.

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Mucous membrane

A mucous membrane or mucosa (plural, mucosae or mucosas; Latin tunica mucosa) is a lining of mostly endodermal origin.

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Nobel Prize

The Nobel Prize (Swedish definite form, singular: Nobelpriset; Norwegian: Nobelprisen) is a set of annual international awards bestowed in a number of categories by Swedish and Norwegian committees in recognition of academic, cultural and/or scientific advances.

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Ondansetron (INN), originally marketed under the brand name Zofran, is a serotonin 5-HT3 receptor antagonist used to prevent nausea and vomiting caused by cancer chemotherapy, radiation therapy, surgery and gastroenteritis.

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An ox (plural oxen), also known as a bullock in Australia and India, is a bovine trained as a draft animal.

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Peptic ulcer

Peptic ulcer disease (PUD), also known as a peptic ulcer or stomach ulcer, is a break in the lining of the stomach, first part of the small intestine, or occasionally the lower esophagus.

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Percy Lavon Julian

Percy Lavon Julian (April 11, 1899 – April 19, 1975) was an American research chemist and a pioneer in the chemical synthesis of medicinal drugs from plants.

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Peripheral edema

Peripheral edema is edema (accumulation of fluid causing swelling) in tissues perfused by the peripheral vascular system, usually in the lower limbs.

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Pharmaceutical drug

A pharmaceutical drug (also referred to as a medicinal product, medicine, medication, or medicament) is a drug used to diagnose, cure, treat, or prevent disease.

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Philip Showalter Hench

Philip Showalter Hench (February 28, 1896 – March 30, 1965) was an American physician.

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Phospholipase A2

Phospholipases A2 (PLA2s) are enzymes that release fatty acids from the second carbon group of glycerol.

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Phospholipids are a class of lipids that are a major component of all cell membranes.

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Physiology is the scientific study of the normal function in living systems.

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Prednicarbate is a relatively new topical corticosteroid drug.

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Prednisolone is a synthetic glucocorticoid, a derivative of cortisol, which is used to treat a variety of inflammatory and auto-immune conditions.

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Prednisone is a synthetic corticosteroid drug that is particularly effective as an immunosuppressant drug.

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Progesterone (abbreviated as P4), also known as pregn-4-ene-3,20-dione, is an endogenous steroid and progestogen sex hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species.

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The prostaglandins (PG) are a group of physiologically active lipid compounds having diverse hormone-like effects in animals.

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Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.

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Retinopathy is persistent or acute damage to the retina of the eye.

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Rhinitis or coryza is irritation and inflammation of the mucous membrane inside the nose.

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Rhizopus is a genus of common saprophytic fungi on plants and specialized parasites on animals.

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Russell Earl Marker

Russell Earl Marker (March 12, 1902 – March 3, 1995) was an American chemist who invented the octane rating system when he was working at the Ethyl Corporation.

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Sarcoidosis, also called sarcoid, is a disease involving abnormal collections of inflammatory cells (granulomas) that can form as nodules in multiple organs.

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A steroid is a type of organic compound that contains four cycloalkane rings arranged in a characteristic configuration.

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Steroid 11-beta-hydroxylase

Steroid 11β-hydroxylase is a steroid hydroxylase found in the zona glomerulosa and zona fasciculata.

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Steroid hormone

A steroid hormone is a steroid that acts as a hormone.

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Steroid-induced osteoporosis

Steroid-induced osteoporosis (SIOP) is osteoporosis arising due to use of glucocorticoids (steroid hormones) - analogous to Cushing's syndrome and involving mainly the axial skeleton.

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Stress (biology)

Physiological or biological stress is an organism's response to a stressor such as an environmental condition or a stimulus.

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Laboratorios Syntex SA was a pharmaceutical company formed in Mexico City in 1944 by Russell Marker to manufacture therapeutic steroids from the Mexican yams called cabeza de negro (Dioscorea mexicana) and Barbasco (Dioscorea composita).

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Systematic review

A systematic review (also systematic literature review or structured literature review, SLR) is a literature review focused on a research question that tries to identify, appraise, select and synthesize all high quality research evidence relevant to that question.

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Systemic lupus erythematosus

Systemic lupus erythematosus, often abbreviated as SLE or lupus, is a systemic autoimmune disease (or autoimmune connective tissue disease) in which the body’s immune system mistakenly attacks healthy tissue.

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Tadeusz Reichstein

Tadeusz Reichstein (20 July 1897 – 1 August 1996) was a Polish chemist residing in Switzerland and the Nobel Prize in Physiology or Medicine laureate (1950).

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Teratology is the study of abnormalities of physiological development.

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Tixocortol pivalate

Tixocortol pivalate is a corticosteroid.

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Tobramycin/dexamethasone (INNs, trade name Tobradex, Tobrason in Jordan) is a prescription medication in the form of eye drops and eye ointment, marketed by Alcon.

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Triamcinolone is a long-acting synthetic corticosteroid given orally, by injection, by inhalation, or as a topical ointment or cream.

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Triamcinolone acetonide

Triamcinolone acetonide is a synthetic corticosteroid used to treat various skin conditions, to relieve the discomfort of mouth sores, and in nasal spray form, to treat allergic rhinitis.

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Ulcerative colitis

Ulcerative colitis (Colitis ulcerosa, UC) is a form of inflammatory bowel disease (IBD) that causes inflammation and ulcers in the colon.

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The Upjohn Company was a pharmaceutical manufacturing firm founded in 1886 in Kalamazoo, Michigan by Dr. William E. Upjohn, an 1875 graduate of the University of Michigan medical school.

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Uveitis (also known as iridocyclitis) is the inflammation of the uvea, the pigmented layer that lies between the inner retina and the outer fibrous layer composed of the sclera and cornea.The uvea consists of the middle layer of pigmented vascular structures of the eye and includes the iris, ciliary body, and choroid.

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Vertebrates comprise any species of animals within the subphylum Vertebrata (chordates with backbones).

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Vitiligo is a chronic skin condition characterized by portions of the skin losing their pigment.

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Zona fasciculata

The zona fasciculata constitutes the middle zone of the adrenal cortex, sitting directly beneath the zona glomerulosa.

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Zona glomerulosa

The zona glomerulosa of the adrenal gland is the most superficial layer of the adrenal cortex, lying directly beneath the renal capsule.

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Steroid 21-hydroxylase is a cytochrome P450 enzyme that is involved with the biosynthesis of the steroid hormones aldosterone and cortisol.

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[1] https://en.wikipedia.org/wiki/Corticosteroid

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